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Gedung Dharma Pengabdian, Department of Chemistry, Faculty of Engineering, Kampus Tepadu Universitas Bangka Belitung Balunijuk, Kab. Bangka, Prov. Kep. Bangka Belitung
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Stannum : Jurnal Sains dan Terapan Kimia
ISSN : 2714674X     EISSN : 27148173     DOI : https://doi.org/10.33019/jstk
Jurnal Sains dan Terapan Kimia published research article, minireview/review, and short communication that included studies in Inorganic Chemistry, Organic Chemistry, Analitycal Chemistry, Biochemistry, Physical Chemistry, Computational Chemistry, Chemical Engineering, and Applied Chemistry.
Articles 94 Documents
Modelling of Flavanoid Derivatives from Leucaena leucocephala as Anti-UV Alfanaar, Rokiy; Manurung, Tety Wahyuningsih; Ariefin, Mokhamat
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 1 (2024): April 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i1.4396

Abstract

While UV light has benefits for life, excessive exposure to UV light also has negative effects on humans. Examples of the negative effects of UV exposure include cancer. Therefore, the exploration for materials that can be used as anti-UV continues to grow. One of them is extract from Leucaena leucocephala leaves. To study the potential of a compound as anti-UV, one method can use a molecular modeling approach using the semi-empirical method. Based on this, 8 flavone-derived compounds contained in L. leucocephala leaf extract were modeled with a semi-empirical approach using the PM3 method, and electronic-transition was calculated using ZINDO/S. The geometry optimization results showed that the bond length between carbon atoms in flavonoid tururnans did not change significantly with the difference in functional groups. However, there is a significant difference in the dihedral angle of the compound due to the repulsion of functional groups. The results of the electronic transition calculation showed that all flavonoid derivatives 1-8 are active in the UV A, UV B, and UV C regions. So it can be said that flavones 1-8 have potential as anti-UV. In addition, the energy level of HOMO-LUMO compounds was also calculated. Flavonoid 1 has the smallest Eg while flavonoid 8 has the largest Eg
Ekstrak Daun Meniran (Phyllanthus niruri L.) : Bagaimana Pengaruhnya Terhadap Jumlah Trombosit di Dalam Darah? Sumiati, Risma Laila; Baehaki, Farhan; Nurdin, Nurdin; Pakpahan, Suyarta Efrida
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 1 (2024): April 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i1.4401

Abstract

Thrombocytopenia is a condition in which the platelet count is below normal (<150,000-450,000 cells/mm3). Until now, the treatment of thrombocytopenia has not yet found a specific drug and there are side effects from chemical treatment, so alternative solutions are needed, one of which is the use of meniran leaves (Phyllanthus niruri L.). The meniran plant is a wild plant that is often found in the wild, on the streets, as well as vacant land so that people can easily get these plants. The aim of this research was to determine the effect of meniran leaf extract (Phyllanthus niruri L.) on the number of platelets in mice induced by sodium phenytoin. The method used in this research was True Experimental with Pretest and Posttest with Control Group Design consisting of 5 groups which aimed to determine the effect of meniran leaf extract on platelet counts. The data collection technique used in this study used primary data, which was obtained from the results of examining platelet counts on day 0, day 3 after induction and day 7 after treatment with meniran leaf extract (Phyllanthus niruri L.). Then the data obtained was tested using SPSS with the non-parametric Kruskal-Wallis and Mann-Whitney tests. From 25 experimental animals, the results showed that there was a relatively significant increase in the number of platelets after being given therapy with meniran leaf extract (Phyllanthus niruri L.) but there was no difference between each dose. Based on the research results, it can be concluded that meniran leaf extract (Phyllanthus niruri L.) has an effect on increasing the number of platelets.
The Pirdot Leaves Extract (Saurauia vulcani Korth) As Natural Antioxidant to Inhibit Oxidation Reaction of Crude Palm Oil (CPO): Ekstrak Daun Pirdot (Saurauia vulcani Korth) sebagai Antioksidan Alami untuk Menghambat Reaksi Oksidasi pada Crude Palm Oil (CPO) Musa, Weny J A; Harianja, Lokky Sardomu; Sriwijayanti, Sriwijayanti; Yulianti, Nani; Situmeang, Boima
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 2 (2024): October 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i2.4464

Abstract

The Pirdot plant (Saurauia vulcani Korth) is a wild plant that grows abundantly in tropical regions such as in North Sumatra. The active compounds found in Pirdot plant leaves are known to have good antioxidant activity. The aim of this research is to evaluate the n-hexane and methanol extracts of Pirdot plant leaves in inhibiting oxidation in crude palm oil (CPO). In this study, the Pirdot plant leaves were extracted using n-hexane (EHP) and methanol (EMP) solvents. The effectiveness of adding both extracts to the quality of CPO was tested for eight days using the parameters of free fatty acid content and peroxide value. The results of the effectiveness test for adding both extracts to CPO showed a good inhibitory effect on the oxidation reaction in CPO. The EMP extract at a concentration of 5000 ppm was more effective in maintaining the quality of CPO for 8 days, with a free fatty acid content of 3.09% and a peroxide value of 14.03 meq O2/kg.
Ionic Conductivity Test of Chitosan Solid Electrolyte Polymer Membrane with the Addition of Ionic Liquid Multazam, Multazam; Ridwan, Mohammad Ibnu; Ndruru, Sun Theo C.L.
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 1 (2024): April 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i1.4491

Abstract

Lithium ion batteries are an alternative choice for fulfillment as an energy source. Beside that, lithium ion batteries are also use as energy storage. However, lithium ion batteries still use a liquid electrolyte which has the advantages of being toxic, explosive, and corrosive. So we need an alternative to replace liquid electrolyte, namely solid electrolyte membranes. The aim of this research is to determine the effect of adding ionic liquid [EMIm]Ac to chitosan polymer as a solid electrolyte polymer (SEP) membranes. Based on the resulta obtained, chitosan has been successfully isolated from chitin. Chitin isolated from shrimp shells. Based on the ionic conductivity value, the SEP membrane with the addition of 15% [EMIm]Ac ionic liquid has the highest ionic conductivity value, namely 5.02 x 10-5 S cm-1.
Utilization Analysis of the Ethyl Acetate Fraction of Cumin Leaves (Plectranthus amboinicus) as an Antimicrobial against Staphylococcus aureus using LC-MS Martha, Rahma Diyan; Fajri, Ayu Insa; Danar, Danar; Kholifah, Siti Nurriyatul; Parbuntari, Hesty
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 2 (2024): October 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i2.4528

Abstract

The research investigates the antibacterial potential of cumin leaves due to their rich composition of flavonoid compounds, alkaloids, saponins, and tannins. The study's objectives encompass assessing the antibacterial efficacy of cumin leaf's ethyl acetate fraction against Staphylococcus aureus bacteria, identifying the concentration of this fraction yielding the most substantial inhibition zone, and characterizing the compound composition within the fractionated cumin leaf extract. Extraction involved maceration using 96% ethanol and fractionation through water, n-hexane, and ethyl acetate solvents. The ethyl acetate fraction's phytochemical screening affirmed the presence of flavonoids, alkaloids, saponins, and tannins. Liquid chromatography-mass spectrometer (LC-MS) analysis pinpointed the top two peaks as flavonoid compounds. Antibacterial assessments, executed via paper disc diffusion method, employed concentrations of 15%, 20%, and 25% of the ethyl acetate cumin leaf extract against Staphylococcus aureus, each repeated thrice. The 20% concentration exhibited the most substantial inhibition zone, averaging 23.1mm, compared to 16.8mm for 15% and 19.6mm for 25%, indicating its optimal efficacy against S. aureus growth. Statistical analysis employing ANOVA testing underscored the significance of the ethyl acetate cumin leaf fraction's concentration variations on S. aureus, as evidenced by a p-value of 0.00 (below the significance threshold of 0.05). This underscores the impact of the ethyl acetate cumin leaf fraction's concentrations on inhibiting S. aureus growth. The findings shed light on the potential of cumin leaves as a source of antimicrobial agents, with the 20% ethyl acetate fraction exhibiting notable effectiveness, opening avenues for further exploration and applications in antibacterial research.
Analysis Of Caffeine In Packaged Drinks Using Thin Layer Chromatography (TLC) and Spectrophotometry Method Munir, Muhammad Abdurrahman; Emelda, Emelda; Fatmawati, Annisa; Nurhidayanti, Nurhidayanti
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 1 (2024): April 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i1.4564

Abstract

Caffeine is a natural alkaloid compound found in plants in the leaves, seeds and fruit. The decision of the Food and Drug Supervisory Agency regarding provisions for supervision of supplements in Chapter VIII Article 18 paragraph two states that caffeine levels must not exceed 150 mg/day. The aim of this research was to find out caffeine level in energy beverages. This research method applied the UV-Vis spectrophotometry method and the TLC method. The maximum wavelength obtained in this study was 272.55 nm and the linear results and correlation coefficient obtained were obtained. The linearity value obtained at y= 0.0381x + 0.3285 with the correlation equation R2= 0.9389. Caffeine levels obtained from “brand A” energy drink powder samples for first replicate at 49.59 mg/g, second replicate was 48.78 mg/g, third replicate was 47.15 mg/g, and “brand B” sample for first replicate was 31.5625 mg/g, second replicate at 32.375 mg/g. The caffeine levels obtained in the “brand C” sample from first replicate at 59.43 mg/g, second replicate was 60.28 mg/g, and third replicate was 60.09 mg/g. The results of the standard Rf value for caffeine standard were 0.7, the “brand A” energy drink powder sample was 0.75, the “brand B” sample was 0.75 and the “brand C” was 0.75. The conclusion from this research was that the maximum wavelength was 272.55 nm, which was slightly different from the theoretical maximum wavelength of pure caffeine, namely 273 nm. The caffeine levels obtained for samples of energy drink powder from brands A and B met the requirements because it was <50 mg/package and brand C did not meet the requirements because it was >50mg/package. The Rf value results are satisfactory because they were at range 0.2-0.8.
Concentration Effect of MgO/K2O Catalyst on Transesterification of Castor Seed (Ricinus communis) Oil: Pengaruh Konsentrasi Katalis MgO/K2O pada Transesterifikasi Minyak Biji Jarak (Ricinus communis) Santoso, Aman; Sumari, Sumari; Asrori, Muhammad Roy; Ni’mah, Irsyadatun
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 2 (2024): October 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i2.4692

Abstract

Fatty acid methyl esters can be obtained from the synthesis of vegetable oil with methanol using a base catalyst. Vegetable oil has the potential as biodiesel feedstock, the methyl ester character of various vegetable oils is different as from castor seed oil. Synthesis of methyl esters by transesterification reaction with the addition of a heterogeneous catalyst, namely MgO/K2O. The purpose of this study was to synthesize methyl esters from castor seed oil with MgO/K2O catalyst and to determine the yield and character. The research went through 6 stages which included (1) isolation of castor seed oil, (2) determination of free fatty acid (ALB) levels of castor seed oil, (3) manufacture of MgO/K2O catalyst (4) esterification of castor seed oil with H2SO4 catalyst (5) transesterification of jatropha seed oil with methanol and various variations in the concentration of the catalyst MgO/K2O 1%, 2%, 3%, (6) characterization of the synthesized methyl ester which includes tests of density, viscosity, acid number, refractive index and moisture content. The results showed that the concentration of MgO/K2O had an effect on the synthesis of methyl esters from castor seed oil, where the optimization condition was achieved at a concentration of 2% MgO/K2O with a yield of 97.99%. The methyl ester character which is synthesized from castor seed oil with a 2% MgO/K2O catalyst is having a density of 1.0244 g/mL, a viscosity of 22.531 cSt, an acid number of 2.81 g KOH/g methyl ester, a refractive index of 1.456, and a moisture content. 0.035%.
In Silico Study of Pomegranate Peel Polyphenols as Breast Anticancer Ummah, Khoirotul; Zummah, Atiqoh
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 1 (2024): April 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i1.4817

Abstract

Breast cancer is one of the causes of women’s death. Estrogen-α receptors are one of the targets for breast cancer treatment because it plays a role in cancer cell proliferation. Several studies have stated that Flavonoid compounds have high activity in inhibiting the growth of breast cancer cells. This study aims to inhibit polyphenolic compounds in pomegranate peel (gallic acid, cafeic acid, ellagic acid, and chlorogenic acid) against estrogen receptors-α through molecular docking. The 3D structures of the polyphenolic compounds were obtained from the PubChem database and the estrogen-α receptors from the Protein Data Base. Molecular docking simulations were carried out using AutoDock Vina and supporting software such as Biovia Discovery Studio Client 4.1, AutoDockTools 1.5.6, PyMOL, and LigPlot. The results showed that the four polyphenolic compounds had a better potential to inhibit estrogen-α receptors than tamoxifen. The inhibitory potential is evidenced by the low affinity of ligand-protein binding energy (approximately -5.4 to -9.0 kcal/mol). The phenol group of polyphenolic compounds can strengthen the ligand-protein interactions through hydrogen bonds with the active site of ER-ꭤ proteins. Hydrophobic and π-π stacking interactions between polyphenolic and the active site of proteins also support the inhibition potential of polyphenolic compounds. The conclusion is that the polyphenolic compounds in pomegranate peel have the potential as breast anticancers.
Utilization of Iron (Stainless Steel) Waste for Making Prussian Blue Pigment: Pengaruh Konsentrasi Katalis MgO/K2O pada Transesterifikasi Minyak Biji Jarak (Ricinus communis) Shohih, Esa Nur; Yudha, Cornelius Satria; Gustiana, Himmah Sekar Eka Ayu; Pradifta, Dian Rama; Simatupang, Ilmi Utari; Maharani, Kristina Dewi; Sa’adah, Muftiyasfu Tahshilus
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 2 (2024): October 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i2.4862

Abstract

The increasing use of household materials made of stainless steel also causes more metal waste to be produced. Stainless waste is considered dangerous because it contains several heavy metal compounds such as Ci, Pb, Ni, Fe, and others, so it is necessary to treat stainless waste. Stainless slag and stainless dust can be processed into products with high selling value such as pigments or dyes. In this research, Prussian Blue pigment was synthesized from Fe waste obtained from iron fiber waste. Apart from knowing the yield of the Prussian Blue synthesis, the effect of adding TiO2 on the intensity of the resulting color was observed. This study used a hydrometallurgical method using acid leaching to produce Prussian blue color pigments. The Prussian blue pigment conversion value produced in experiment 1 was 79.63%, experiment 2 was 80.36%, experiment 3 was 83.63%, and experiment 4 was 82.40%. The yield value of Prussian blue pigment in experiment 1 was 1.230 gram Prussian blue/gram iron, experiment 2 was 1.142 gram Prussian blue/gram iron, experiment 3 was 1.305 gram prussian blue/gram iron, and experiment 4 was 1.807 gram prussian blue/gram iron. Overall this method can process waste iron (stainless steel) into Prussian blue color pigment.
Analysis of Diazo Quinolinone Complexes with Various Metal Ions Rumengan, Stefan Marco; Ummah, Khoirotul; Mardliyah, Ana; Wijaya, Jefry; Tambalean, Febrindah Ester; Tengker, Soenandar Milian; Saiya, Abdon; Karundeng, Marlina; Paat, Vlagia Indira
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 1 (2024): April 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i1.4882

Abstract

Quinolones are heterocyclic compounds that are important in medicine and materials for DSSCs or OLEDs. One thing that is rarely studied is the ability to detect metal ions. Diazo groups have an important role in forming complexes with metal ions. This research aims to obtain initial information regarding the metal detection capabilities of diazo quinolinone compounds. The compound 7-[(2,4-dihydroxyphenyl)diazenyl]-4-methyl-2-quinolinone is the test target. Tests were carried out with various metal ions in MeOH. Next, the wavelength of the complex was determined using a UV-Vis spectrophotometer. The results of complex analysis of Compound 2 with various metal ions show the potential to be an indication of the presence of metal ions.

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