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Jurnal Riset Kefarmasian Indonesia
Published by Asosiasi Pendidikan Diploma Farmasi Indonesia
ISSN : 2656131x     EISSN : 26558289     DOI : https://doi.org/10.33759/jrki
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
JURNAL RISET KEFARMASIAN INDONESIA adalah jurnal yang diterbitkan online dan diterbitkan dalam bentuk cetak. Jurnal ini diterbitkan 3 kali dalam 1 tahun (Januari, Mei dan September) Jurnal ini diterbitkan oleh APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) Lingkup jurnal ini mencakup Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Organik Bahan Alami, Biokimia, Analisis Kimia, Kimia Fisik, Biologi, Mikrobiologi, Kultur Jaringan, Botani dan hewan yang terkait dengan produk farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Nutrisi dan Kesehatan Masyarakat.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 121 Documents
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PENETAPAN KADAR ALKALOID TOTAL PADA EKSTRAK N-HEKSAN DAN ETANOL BIJI KETUMBAR (Coriandrum sativum) MENGGUNAKAN SPEKTROFOTOMETER UV-Vis lindawati setyaningrum; Dhina Ayu Susanti
Jurnal Riset Kefarmasian Indonesia Vol 4 No 3 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i3.268

Abstract

Coriander (Coriandrum sativum) is one of the medicinal plants which is known to contain secondary metabolites such as flavonoids, tannins, terpenoids, saponins, steroids, and alkaloids. Alkaloids have therapeutic effects as antimalarials and cancer. Research in determining the alkaloids in coriander was carried out by separating the alkaloids from other substances using the soxhlet method extraction with two solvents ethanol and n-hexane. The total alkaloid content is determined using a UV-VIS spectrophotometer at wavelength 351,5 nm. The reaction of alkaloids with Bromocresol green (BCG) is obtained to form a yellow product. The use of berberine standard was obtained the total alkaloid content of ethanol and n-hexane extract in coriander seed (Coriandrum sativum) were 0.524% and 0.583% respectively, and the ratio of total alkaloid content of ethanol extract was smaller than that of n-hexane extract.
UJI RESISTENSI BAKTERI Escherichia coli DARI SUMBER AIR BAKU DI KARAWANG TERHADAP ANTIBIOTIK SIPROFLOKSASIN Fuji Ayu Diniarti; Ahsanal Kasasiah; Indah Laily Hilmi
Jurnal Riset Kefarmasian Indonesia Vol 4 No 3 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i3.281

Abstract

Infectious diseases are included in the ten most common diseases in Indonesia. The disease can be overcome by the use of antimicrobials, one of which is antibiotics. Antibiotics are drugs used to treat infections caused by bacteria. Excessive use of antibiotics without clear indications can have an impact on the occurrence of bacterial resistance to these antibiotics. One of the bacteria that is resistant to antibiotics is Escherichia coli. This study aims to determine the sensitivity of Escherichia coli isolated from raw water sources in Karawang to the antibiotic ciprofloxacin. Samples were obtained from irrigation water which is the source of raw water for one branch of Perumdam in Karawang. The samples were tested using Lactose Broth (LB) media, then confirmed using Eosin Methylene Blue (EMBA) media to confirm the presence of Escherichia coli bacteria equipped with Gram stain. Bacterial resistance test was carried out using Mueller Hinton Agar (MHA) media with disc diffusion method. The results showed that the average diameter of the clear zone formed around the paper disc was 30.16 mm. The isolates showed intermediate results against the antibiotic ciprofloxacin.
EVALUASI FORMULASI MASKER CLAY DARI EKSTRAK ETANOl DAUN PEPAYA (CARICA PAPAYA L.) SEBAGAI ANTI JERAWAT Fauziah Fauziah; Nurliza Alvanny; Kiki Andalia
Jurnal Riset Kefarmasian Indonesia Vol 4 No 3 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i3.283

Abstract

Papaya Leaf Extract is known to contain alkaloid and flavonoid compounds that can inhibit the preparation of peptidoglycan in bacterial cells and reduce immunity in target organisms. For ease of use of papaya leaf extract, it is formulated in the form of a mask. This study aims to formulate a clay mask from papaya leaf ethanol extract and the effectiveness of anti-acne use of clay mask preparation of papaya leaf ethanol extract for 4 weeks. The method used in this study is an experimental method carried out at the AKAFARMA laboratory in Banda Aceh. The samples used were Formula 0, Formula 1, Formula 2 and Formula 3 masks of papaya leaf ethanol extract with concentrations for Formula 1 (2.5 %), Formula 2 (5%) and Formula 3 (7%). The results of the research on the physical properties and stability of the clay mask preparation on organoleptic testing showed that all formulas did not change color and odor for 4 weeks, but there was a change in shape at F0, FI, and FII on the 28th day. The homogeneity test of all preparations showed a homogeneous arrangement. The resulting pH test is 5.7-6.5, the resulting dispersion test is 5-5.5. The dried preparation test resulted in 25-30 minutes. and the anti-acne effectiveness test of each mask preparation F0, FI, FII, and FIII the average percentage reduction in the number of acne was 20.83%, 22.63%, 28.75%, and 50%. Papaya leaf ethanol extract clay mask FIII (7.5%) was the maximum in reducing the number of pimples on the volunteers' faces. The conclusion in this study is that papaya leaves can be formulated as a clay mask.
FORMULASI DAN EVALUASI FISIK MASKER GEL PEEL OFF DARI SERBUK SISIK IKAN MUJAIR (Oreochromis mossambicus) Mutmainnah Mutmainnah; Abulkhair Abdullah; Muvida Syawie
Jurnal Riset Kefarmasian Indonesia Vol 4 No 3 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i3.290

Abstract

Masker gel peel off merupakan salah satu kosmetik yang digunakan untuk perawatan kulit yang dapat memutihkan, mengecilkan pori-pori, melembabkan dan menutrisi kulit. Salah satu bahan yang dapat dijadikan bahan utama masker gel peel off adalah sisik ikan mujair (Oreochromis mossambicus). Sisik ikan mujair mengandung kolagen yang bermanfaat sebagai antiaging. Penelitian ini bertujuan untuk mendapatkan formula masker gel peel off dari sisik ikan yang terbaik dengan memvariasikan konsentrasi PVA (5% dan 10%) dan HPMC (2% dan 4%). Dalam penelitian ini dibuat 4 formula yang berbeda. Pada sediaan dilakukan pengujian karakteristik yang meliputi uji organoleptis, uji homogenitas, uji pH, uji daya sebar, uji waktu mengering, dan uji hedonik. Hasil penelitian menunjukkan sediaan yang dibuat sudah memenuhi kriteria. Semua formula memiliki tekstur semi padat, beraroma jeruk, dan berwarna abu-abu dan semua formula menunjukkan homogenitas yang baik. Hasil uji pH diperoleh: F1 (5,0), F2 (5,6), F3 (5,5), dan F4 (5,4). Hasil uji daya lekat diperoleh: F1 (400 g : 5,2 cm), F2 (600 g : 5,2 cm), F3 (600 g : 5,4 cm), dan F4 (600 g : 5,4 cm). hasil uji waktu mengering: F1 (55 menit), F2 (33 menit), F3 (33,3 menit), F4 (56,3 menit). Dapat disimpulkan bahwa serbuk sisik ikan mujair dapat dijadikan sediaan masker gel peel off. Formula 2 menjadi formula terbaik dengan konsentrasi PVA 10% dan HPMC 2%.
FORMULASI LULUR BODY SCRUB BERAS KETAN HITAM (ORYZA SATIVA VAR. GLUTINOSA) DENGAN PERPADUAN YOGURT SEBAGAI ZAT AKTIF Shelly Dwi Agata; Lukky Jayadi
Jurnal Riset Kefarmasian Indonesia Vol 4 No 3 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i3.293

Abstract

Scrub is a cosmetic preparation for skin care that functions as an abrasive in the form of scurb granules that can remove dead skin cells from the epidermis. The scrub used in this study was derived from black glutinous rice (Oryza Sativa Var. Glutinosa) which contains antioxidant components and can help activate vitamin B1 which helps maintain healthy skin and helps skin look brighter. In addition, the components of the active substance are also needed. Yogurt was chosen as the active ingredient of the preparation because it has Alpha Hydroxy Acid (AHA) which can help the exfoliation process and help remove dead skin cells and increase the skin's natural moisture factor. The purpose of making body scrub preparations using yogurt as an active substance with varying concentrations of 0%, 5%, 10% and 15%. This research was conducted experimentally. The physical quality test of the preparation includes organoleptic test, homogeneity test, pH test, adhesion test, dispersibility test, stability test, and emulsion type test. The results show that the preparations made meet the physical evaluation of the scrub preparations meet the quality requirements, meet the organoleptic quality evaluation, namely the formulation of the scrub preparations F0, F1, F2, and F3 with semi-solid texture, purplish gray color with a mixture of black glutinous rice and yogurt. Each preparation is homogeneous. Emulsion type o/w. pH ranged from 7, 45 - 6, 74. It complies with the quality requirements of the spreadability test and has good emulsion stability. The conclusion of this study is that the F3 formulation with the addition of 15% yogurt has the best physical quality in the organoleptic test, homogeneity test, pH test, dispersibility test, stability test, and emulsion type test.
STUDI TINGKAT PENGETAHUAN DAN PERILAKU SWAMEDIKASI OBAT ANALGESIK PADA PASIEN DI APOTEK KOTA SAMARINDA Aprilia Diah Susanti; Sinta Ratna Dewi
Jurnal Riset Kefarmasian Indonesia Vol 4 No 3 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i3.298

Abstract

Self-medication is a behavior of the community to perform health treatment for themselves without having to consult with health workers. Analgesic is a non-steroidal anti-inflammatory drug (NSAID) group that is used to relieve pain, so it is often used by people to treat pain without losing awareness. This study aimed to describe the study of the level of knowledge and behavior of self-medication of analgesic drugs at the Samarinda City Pharmacy. This research is a type of quantitative research with the cross-sectional method. Sampling using non-probability sampling by purposive sampling. The sample used in this study was 147 respondents. The results showed that the majority of respondents on drug selection indicators (89.1%), drug class (83.65%), how to use (92.5%), and drug storage (75.96%) with behavioral levels on the selection indicator. drug (89.8%), drug class (87.1%), method of use (83.7%), and drug storage (77.5%). The patient's level of knowledge and the behavior of self-medication of analgesic drugs is included in the good category.
PENGARUH KOMBINASI SODIUM LAURIL SULFAT DAN NATRIUM KLORIDA TERHADAP KARAKTERISTIK SAMPO EKSTRAK LIDAH BUAYA Luh Nela Andriani; I Gusti NAWW Putra; I Ketut Tunas
Jurnal Riset Kefarmasian Indonesia Vol 4 No 3 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i3.304

Abstract

The shampoo industry in Indonesia is growing. The shampoo formulation contains 2 main ingredients, namely sodium lauryl sulfate (SLS) and sodium chloride (NaCl). One example of natural ingredients in the manufacture of shampoo is Aloe Vera (Aloe vera L.). This study aims to determine the effect of variations in the concentration of SLS and NaCl on the physical and chemical properties of shampoo. This research is an experimental study with 8 formulas. Includes organoleptic test, homogeneity test, viscosity test, foam height test, specific gravity test, and pH test. Making shampoo preparations by weighing all ingredients according to each formulation, leaving the shampoo for 1 day before testing for 4 weeks of storage.The results showed that the organoleptic test and the homogeneity test of NaCl and SLS had no effect on shampoo. In the specific gravity test and the pH test of NaCl and SLS there was no dominant influence on the specific gravity of shampoo. In the foam height test, the SLS coefficient value is higher than NaCl so that SLS dominantly affects the height of the shampoo foam. In the viscosity test the coefficient value of NaCl is higher than SLS so that NaCl dominantly affects the viscosity of the shampoo. The conclusion from this research is that NaCl has a dominant influence on the physical properties, namely viscosity, while SLS has a dominant influence on the physical properties, namely the height of the shampoo foam.
FORMULASI SEDIAAN SABUN CAIR EKSTRAK LIDAH BUAYA (Aloe vera L.) Made Galih Dwi Mahayuni; I Gusti Ngurah Agung Windra Wartana Putra; Ni Putu Wintariani
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.309

Abstract

Skin is the external part of body which protects internal organs from external interference, such as bacteria, viruses, cold air, hot sun, exposure to UV radiation, pressure, etc. Maintain clean skin is an important thing to do to prevent skin diseases. The way to keep our skin clean is use a mild soap which is good for the skin. Soap is one of the preparations commonly used in daily life. The ingredients of liquid soap are made up of surfactants, thickeners, preservatives and pH regulators. The presence of surface-active agents in soap is important for cleansing the dirt from the skin. Thickeners are important in the soap to obtain the required viscosity of the formulation. The aim of this study was to determine the characteristics of aloe vera (Aloe Vera L.) liquid soap. This type of research is an experimental study with a completely randomized design. The formula will be tested for physical and chemical properties which include organoleptic tests, viscosity tests, specific gravity tests, foam stability tests, and pH tests. Aloe vera liquid soap in all formulas has physical and chemical characteristics that meet the standards where the viscosity values obtained are 2616-4188 cP, specific gravity 1.067-1.082, foam resistance 61-70%, and pH 6.1-7
PENGARUH VARIASI KONSENTRASI HPMC TERHADAP SIFAT FISIK GEL EKSTRAK KULIT PISANG AGUNG SEMERU (Musa paradisiaca L.) Mikhania Christiningtyas Eryani; Hadi Barru Hakam Fajar Siddiq; Dewi Rashati; Risma Khoiro Safitri
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.320

Abstract

The aims of this study was to determine the effect of HPMC variation concentration to the physical properties of Semeru Agung banana (Musa paradisiaca L.) skin extract gel. Gel was formulated with various HPMC concentration namely F1 (2%), F2 (3%) and F3 (4%). Gel was evaluated organoleptic, homogeinity, pH, viscosity, spreadbility and adhesion value. The results showed that F2 meet the organoleptic requirements while F1 and F3 did not meet. All formulas are homogeneous. The results of the pH test showed that the pH value of F1 was 5.9 ± 0; F2 of 5.8± 0 ; F3 of 5.9 ± 0. The results of the viscosity test showed that the viscosity value of F1 was 150 ± 0 dPas; F2 of 250 ± 0 dPas; F3 of 300 ± 0 dPas. The results of the dispersion test showed that the dispersion value of F1 was 5.6 ± 0.06 cm; F2 of 5.3 ± 0.29 cm ; F3 is 4.0 ± 0.12 cm. The results of the adhesion test showed that the value of the F1 adhesiveness was 11.04 ± 0.43 seconds; F2 of 17.4 ± 1.47 seconds; F3 is 24.2 ± 2.44 seconds. It is known that variations in HPMC concentration affect gel texture, viscosity, spreadability and adhesion, and have no effect on gel smell, color and pH.
ANALISIS DESKRIPTIF TERKAIT PENGETAHUAN PENGGUNAAN ANTIBIOTIK PADA WARGA RW 009 KELURAHAN DUREN SAWIT PERIODE MEI-JUNI 2022 Fachdiana Fidia; Farida Tuahuns; Harum Andini Putri Niode
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.323

Abstract

Infectious diseases remain one of the world's public health concerns, particularly in developing countries. Excessive and inappropriate antibiotics use can lead to the emergence of bacterial resistance and increase the economic burden of health care; additionally. According to a preliminary survey conducted on residents of 009 Community Unit, Duren Sawit Sub-district aged 17-65 in January 2022, it demonstrated that 60% residents believed that antibiotics could treat fever and could be purchased without a prescription 40%. This research aimed to describe the knowledge of antibiotic use in the residents of 009 Community Unit, Duren Sawit Village. The study employed a descriptive quantitative type, where data collection was performed using a questionnaire. This research comprised 237 respondents, who were selected employing the proportional random sampling technique and required the inclusion criteria. The study’s findings indicated that out of 237 respondents, 99 individuals (42%) had good comprehension, 88 individuals (37%) had sufficient comprehension, and 50 individuals (21%) had inadequate comprehension. In summary, suppose described in each indicator, the level of public knowledge for the three indicators was as follows: 118 respondents (50%) have a good understanding of the meaning of antibiotics,104 respondents (44%) have a good understanding of the use of antibiotics, and 140 respondents (59%) had a good understanding of the undesirable effects of the use of antibiotics. The 4 most consumed antibiotics were Amoxicillin (55.7%), Fg Troches (14.3%), Cefixime (8.4%) and Azithromycin (8.4%). While the dose of taking antibiotics ranges from 1x to 4x a day, depends on the type of antibiotics.

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