cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Supomo
Contact Email
jurnal.apdfi@gmail.com
Phone
+6281347065975
Journal Mail Official
jurnal.apdfi@gmail.com
Editorial Address
APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) Jl. Buaran II No. 30 A, I Gusti Ngurah Rai, Klender Jakarta Timur, Indonesia Telp. 021 - 86615593, 4244486. Email : apdfi.2013@gmail.com
Location
Kota adm. jakarta timur,
Dki jakarta
INDONESIA
Jurnal Riset Kefarmasian Indonesia
Published by Asosiasi Pendidikan Diploma Farmasi Indonesia
ISSN : 2656131x     EISSN : 26558289     DOI : https://doi.org/10.33759/jrki
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
JURNAL RISET KEFARMASIAN INDONESIA adalah jurnal yang diterbitkan online dan diterbitkan dalam bentuk cetak. Jurnal ini diterbitkan 3 kali dalam 1 tahun (Januari, Mei dan September) Jurnal ini diterbitkan oleh APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) Lingkup jurnal ini mencakup Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Organik Bahan Alami, Biokimia, Analisis Kimia, Kimia Fisik, Biologi, Mikrobiologi, Kultur Jaringan, Botani dan hewan yang terkait dengan produk farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Nutrisi dan Kesehatan Masyarakat.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 121 Documents
 9   10   11   12   13 
UJI AKTIVITAS ANTIBAKTERI NANOPARTIKEL EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J.R. Forst & G. Forst) TERHADAP BAKTERI Streptococcus mutans Nelsa Fahira; Yayuk Putri Rahayu; Haris Munandar Nasution; M Pandapotan Nasution
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.327

Abstract

Streptococcus mutans is one of the bacteria that plays an important role in the formation of dental caries. One of the plants known to have antibacterial compounds are matoa leaves (Pometia pinnata J.R. Forst & G. Forst) family Sapindaceae. The objective of this research was to determine the antibacterial activity of matoa leaves ethanolic extract nanoparticles is better than matoa leaves ethanolic extract against S. mutans bacteria. The research method was carried out experimentally. Free variables, namely the concentration of matoa leaf ethanol extract (KEDM 25% ; KEDM 50%; and KEDM 75%) and the concentration of nanoparticles of matoa leaf ethanol extract (KNDM 2.5%; KNDM 5%; and KNDM 7.5%). Bound variables are antibacterial activity of ethanol extract and nanoparticles of matoa leaf ethanol extract against S. mutans bacteria. The nanoparticle size of the extract was characterized using a Particle Size Analyzer (PSA). Test of antibacterial activity of ethanol extract and matoa leaf ethanol extract nanoparticles against S. mutans using the diffusion method to Kirby Bauer. The result of the extract nanoparticle size characterization was 324.97 nm. Zone of Inhibition (ZOI) values of antibacterial ethanol extract of matoa leaves against S. mutans were 12.00 mm (KEDM 25%), 12.50 mm (KEDM 50%), and 12.60 mm (KEDM 75%). The antibacterial ZOI values of matoa leaf ethanol extract nanoparticles against S. mutans were 8.00 mm (KNDM 2.5%), 9.06 mm (KNDM 5%), and 10.10 mm (KNDM 7.5%). The conclusion is that ethanol extract of matoa leaves can be used as extract nanoparticles, where the extract nanoparticle concentration of 7.5% already has the ability of antibacterial activity that is close to the concentration of 25% ethanol extract, so that it can be said that the extract nanoparticle preparation can reduce the dose of a drug even though it is in the resistant category compared to Amoxicillin 25 g with the susceptible category.
UJI AKTIVITAS ANTIBAKTERI NANOPARTIKEL EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J.R. Forst & G. Forst) TERHADAP BAKTERI Escherichia coli Huzeila Nisa Siregar; Yayuk Putri Rahayu; Haris Munandar Nasution; M Pandapotan Nasution
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.329

Abstract

Escherichia coli was one of the bacteria that causes diarrhea. Matoa leaves (Pometia pinnata J.R. Forst & G. Forst) ) is a plant from the Sapindaceae family and is known to have antibacterial compounds. This study aims to make ethanol extract of matoa leaves into extract nanoparticles and to determine the antibacterial activity of ethanol extract nanoparticles better than ethanol extract of matoa leaves against E. coli bacteria. This research was conducted experimentally with free variables, namely the concentration of matoa leaf ethanol extract (KEDM 25%; KEDM 50%; and KEDM 75%), and the nanoparticle concentration of matoa leaf ethanol extract (KNDM 2.5%; KNDM 5%; and KNDM 7.5%). The bound variable was the antibacterial activity of ethanol extract and nanoparticles of ethanol extract of matoa leaves against E. coli bacteria. Nanoparticle manufacturing uses the ionic glassing method with chitosan 0.1% and Na-TPP 0.1% (1:1). The nanoparticle size characterization of the extract used a Particle Size Analyzer (PSA). Antibacterial activity test using the diffusion method of Kirby Bauer's agar. The result of the characterization of the extract nanoparticles obtained a size of 324.97 nm. The value of the antibacterial Zone Of Inhibition (ZOI) of matoa leaf ethanol extract was 13.9 mm (KEDM 25%); 14.6 mm (KEDM 50%); and 18 mm (KEDM 75%). The antibacterial ZOI value of the ethanol extract nanoparticles was 6.6 mm (KNDM 2.5%); 7.2 mm (KNDM 5%); and 7.7 mm (KNDM 7.5%). The conclusion of this research was that matoa leaf ethanol extract can be used as an extract nanoparticle, where with a concentration of 2.5% extract nanoparticles already has antibacterial activity capability which is equivalent to half the dose of 25% ethanol extract concentration of matoa leaves, so it can be said that the extract nanoparticle preparation can reduce the dose of a drug by up to half the dose, even though it is in the resistant category compared to Tetracycline 30 μg.
FORMULASI DAN UJI STABILITAS SEDIAAN TONER WAJAH EKSTRAK BUAH PARE (Momordica charantia L) SEBAGAI ANTI JERAWAT DENGAN VARIASI SURFAKTAN Muhammad Noor; Siti Malahayati; Kunti Nastiti
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.330

Abstract

Bitter gourd extract (Momordica charantia L) contains secondary metabolites such as flavonoids, alkaloids, and saponins that can be antibacterial against acne-causing bacteria (Propionibacterium acnes). Momordica charantia L., could make into facial toner preparations to prevent the emergence and worsen acne. It is formulated with various concentrations of polysorbate 20 and performs stability testing. This study aimed at the optimal formula and analyzed the variations in the concentration effect of polysorbate 20 on the bitter gourd extract facial toner preparation. Bitter gourd extract would make into facial toner preparation with variations in the concentration of polysorbate 20. The accelerated stability test with the cycling test method includes before and after organoleptic, homogeneity, viscosity, and pH tests. The organoleptic stability result shows both stable formulas had the same liquid form, clear brown color, and characteristic rose odor. All formulations are stable on homogeneity, in which the particles are evenly mixed. The Formula I viscosity value is constantly stabilized and meets the parameters, while formula II is not but meets the parameters. The pH stability values of both formulas are stable and meet the parameters. Formula I is more optimal than formula II and the difference in surfactant concentration of polysorbate 20 has no effect on organoleptic, homogeneity, and pH but will affect viscosity.
EVALUASI FISIK KRIM ANTIINFLAMASI EKSTRAK KULIT BAWANG MERAH DENGAN VARIASI KONSENTRASI TRIETANOLAMIN DAN ASAM STEARAT April Nuraini; Dianita Rahayu Puspitasari; Ratri Rokhani
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.338

Abstract

Inflammation is the body's defense function against the entry of organisms and other disturbances. The drugs used often have an effect on gastrointestinal disorders, so other alternative treatments are being developed that can minimize side effects. The quarcetin content of shallot skin extract, which has anti-inflammatory activity, is formulated in a cream dosage form. The emulsifiers in the m/a cream formula are stearic acid and triethanolamine (TEA). This study aims to determine the physical evaluation of an anti-inflammatory cream containing shallot skin extract with variations in concentrations of TEA and stearic acid. The method used in this study is the experimental method. Formulations I, II, and III with varying concentrations of TEA and stearic acid (2:8%, 3:10%, and 4:12%) were used. Tests carried out included organoleptic tests, homogeneity, pH, spreadability, and adhesion. The cream formula passed the organoleptic test with a distinctive shallot smell, semi-solid form, brownish red color, all formulas were homogeneous, pH 5.264-6.417, spreadability 3.849-6.251 cm, and adhesion 83-132 seconds. Higher concentrations of TEA and stearic acid had an effect on adhesion and spreadability but had no effect on organoleptic properties, homogeneity, or pH. Onion skin extract cream with a concentration of TEA:2%:8% stearic acid gave the best physical quality.
PROFIL PENGETAHUAN PENDUDUK TERHADAP OBAT GENERIK, MEREK DAN PATEN Mexsi Mutia Rissa; Nabila Ayu Puspita
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.339

Abstract

Republic of Indonesia Law Number 36 of 2009 states that medicine is a combination of ingredients, including biological products that are used to affect or investigate physiological systems or pathological conditions in the framework of establishing a diagnosis, prevention, cure, recovery, health promotion and contraception for humans. Generic drugs are drugs whose patents have expired, so all pharmaceutical companies can produce them without the need to pay for patents. Branded drugs are drugs that are marketed under certain trade names registered by the manufacturer. Patented drugs are drugs that have just been produced and marketed by a pharmaceutical company that has had patents for 20 years. The purpose of this study was to determine the profile of the population's knowledge of generic drugs, branded drugs, and patent drugs. The descriptive observational research method by collecting primary data through questionnaires. The results of the study showed that 45 respondents (64.70%) had enough knowledge and 25 respondents (35.70%) had less knowledge. This shows that the profile of the population's knowledge of generic drugs, branded drugs, and patent drugs is considered quite good. The conclusion of this study is that the population's knowledge profile of generic drugs, branded drugs, and patented drugs is included in the sufficient category, namely 64.70%.
FORMULASI DETERJEN RAMAH LINGKUNGAN DENGAN SERBUK SIMPLISIA DAUN WARU (Hibiscus tilliaceus L.) DAN BUAH LERAK (Sapindus rarak DC.) SEBAGAI SURFAKTAN Iif Hanifa Nurrosyidah; Erica Novia Putri; Berlian Adi Satria
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.346

Abstract

The purpose of this study was to develop an environmentally friendly detergent formula containing simplicial powder of hibiscus leaf (Hisbiscus tiliaceus L.) and lerak fruit (Sapindus rerak DC.) and combined with biodegradable surfactants (Decyl Glucoside and Lauryl Glucoside) so that they are easy to biodegrade. The research method includes making liquid detergent using three formulas, namely F I, F II, and F III with variations in the concentration of hibiscus leaf and lerak fruit simplicial powder used. Physical characteristic test of liquid detergent according to the quality requirements of SNI SNI 06-4075-1996 includes organoleptic, pH, foam stability test, and contamination analysis by determining the total plate number (ALT). Based on the results of this study, the three detergent formulas have physical characteristics according to the quality requirements of SNI
PENGARUH KONSELING APOTEKER TERHADAP TINGKAT KEPATUHAN MINUM OBAT DAN KADAR GULA DARAH PASIEN DIABETES MELLITUS Annis Rahmawaty; Nanda Widia Anggraeni
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.349

Abstract

Background: Diabetes mellitus is a metabolic disorder characterized by high blood sugar levels. The level of adherence to taking medications plays a very important role in achieving successful treatment and maintaining blood sugar levels within normal ranges, as well as pharmacist counseling is very important in handling DM. Objective: The purpose of this study was to determine the effect of pharmacist counseling on the level of adherence to taking oral antidiabetic drugs in diabetes mellitus patients at the Ngembal Kulon Kudus Health Center. Method: This study is a pre-experimental study designed by One Group Pretest Posttest with cross-sectional data retrieval. Data collection was carried out in March-April 2022 at the Ngembal Kulon Kudus Health Center. Result: This study used spearman correlation test with 0.000 results obtained, wilcoxon test obtained 0.000 results and the paried T-test obtained results of 0.000 which were said to be significantly different before and after pharmacist counseling. Conclusion: Counseling there was a change in compliance in diabetes mellitus patients there was an effect of providing pharmacist counseling on the level of adherence to taking oral antidiabetic drugs using the MGL MAQ questionnaire (p 0.000) and blood sugar levels in demographic data (p 0.000) in diabetes mellitus patients.
UJI EFEK ANALGESIK EKSTRAK DAUN SIRIH HIJAU BANYUWANGI (Piper betle L.) PADA MENCIT PUTIH JANTAN (Mus musculus) Ima Fitria Lestari; Junieta Fara Syafirah; Dita Amanda Deviani
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.351

Abstract

The content of flavonoid compounds in betel leaf is used as a protection as analgesic. The purpose of this study was to test the analgesic effects of Banyuwangi green betel leaf extract (Piper betle L.) on male white mice (Mus musculus). The doses of green betel leaf ethanol extract that were used were 4.696 mg, 9.392 mg and 18.784 mg and the positive control were mefenamic acid. The test animals used in this study were white male mice (Mus musculus) that were adapted for about 3 days in experimental environmental conditions. Based on the results of the study, the analgesic effect test of green betel leaf extract (Piper betle L.) can provide analgesic effectiveness on mice (Mus musculus). Ethanol extracts of green betel leaf (Piper betle L.) at doses of 4.696 mg/kgBW were able to provide a good analgesic effect with good responses to white male mice (Mus musculus). The percentage of analgesic power that was close to the percentage of analgesic power of the gold standard which is 69.23%.
PENYEBAB OBAT KEDALUARSA, OBAT RUSAK DAN DEAD STOCK (STOK MATI) DI GUDANG PERBEKALAN FARMASI GUDANG PERBEKALAN FARMASI RUMAH SAKIT X SURABAYA Diah Nurcahyani; Arina Ayuningtyas; Leo Eladisa G
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.353

Abstract

Drug processing problems in each hospital often occur nowadays, so it is necessary to carry out continuous evaluation to create optimal services in providing good quality patient health. This study aims to describe and analyze the occurrence of expired drugs, damaged drugs and dead stock, to provide policy recommendations for improving drug processing. This study uses a descriptive method, namely research that describes an object in relation to the actual situation. The sample used in this study is the number of expired drugs, damaged drugs and dead stock for the period June - August 2021 compared to the total number of drugs in the hospital. The percentage results for expired drugs were 0.002%, damaged drugs were 0%, dead stock were 0.022%, this was due to changes in prescribing patterns, expiration dates that were too short when receiving drugs from PBF and not maximally checking expired drugs in each unit, so it is necessary to do checking between planning and drug needs as well as improving the ED drug processing system and evaluating the system and evaluating the drug acceptance system in hospitals.
KANDUNGAN BORAKS PADA PENTOL BAKSO DI KECAMATAN BALONGBENDO KABUPATEN SIDOARJO DENGAN METODE SPEKTROFOTOMETRI Adinda Puspita Sari; Herni Setyawati; Djelang Zaenudin
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.354

Abstract

Sodium Tetraborate, also known as Borax, is a chemical compound which is a derivative of metal boron gas (B), used as an antifungal compound, wood preservative, and an antiseptic compound in cosmetics. The use of Borax as a preservative in food has been banned by the government. The purpose of this study was to help and remove the levels of borax found in meatball bulbs. Sampling was determined in Balongbendo District, Sidoarjo Regency. Analysis of the content of Borax compounds in meatball bulbs was carried out qualitatively using the flame method and the tumeric paper test. Quantitative test using the UV-Vis Spectrophotometer method. Based on the results of an analysis of 60 samples of meatball bulbs sold in Balongbendo District, Sidoarjo Regency, 1 sample was positively identified as containing a Borax compound with an average level of 0.162 ppm.

Page 11 of 13 | Total Record : 121

 9   10   11   12   13 

Filter by Year

2019 2023


Reset
Filter By Issues
All Issue Vol 5 No 2 (2023): Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia Vol 4 No 3 (2022): Jurnal Riset Kefarmasian Indonesia Vol 4 No 2 (2022): Jurnal Riset Kefarmasian Indonesia Vol 4 No 1 (2022): Jurnal Riset Kefarmasian Indonesia Vol 3 No 3 (2021): Jurnal Riset Kefarmasin Indonesia Vol 3 No 2 (2021): Jurnal Riset Kefarmasian Indonesia Vol 3 No 1 (2021): Jurnal Riset Kefarmasian Indonesia Vol 2 No 3 (2020): Jurnal Riset Kefarmasian Indonesia Vol 2 No 2 (2020): Jurnal Riset Kefarmasian Indonesia Vol 2 No 1 (2020): Jurnal Riset Kefarmasian Indonesia Vol 1 No 3 (2019): Jurnal Riset Kefarmasian Indonesia Vol 1 No 2 (2019): Jurnal Riset Kefarmasian Indonesia Vol 1 No 1 (2019): Jurnal Riset Kefarmasian Indonesia More Issue