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Contact Name
Prof. Dr. Syafruddin Ilyas, M.Biomed
Contact Email
syafruddin6@usu.ac.id
Phone
+628126555198
Journal Mail Official
ijoep@usu.ac.id
Editorial Address
Jln. Bioteknologi No.1, Kampus USU Padang Bulan, Medan
Location
Kota medan,
Sumatera utara
INDONESIA
IJOEP : International Journal of Ecophysiology
ISSN : -     EISSN : 26560674     DOI : -
Core Subject : Agriculture,
International Journal of Ecophysiology (IJOEP) is a peer-reviewed biannual journal (February and July) published by TALENTA Publisher and organized by Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara (USU) as an open-access journal. It welcomes full research articles in the field of Biological Sciences from the following subject area: Anatomy, Comparative anatomy, Histology, Astrobiology, Biochemistry, Biological engineering, Biogeography, Bioinformatics, Biolinguistics, Biomechanics, Biomedical research, Biophysics, Biotechnology, Synthetic biology, Botany, Phycology, Plant physiology, Cell biology, Chronobiology, Cognitive biology, Conservation biology, Cryobiology, Developmental biology, Embryology, Gerontology, Ecology, Evolutionary biology, Genetics, Genomics, Epigenetics, Immunology, Marine biology, Microbiology, Bacteriology, Mycology, Parasitology, Virology, Molecular biology, Nanobiology, Neuroscience, Paleontology, Pathobiology, Pharmacology, Physiology, Phytopathology, Psychobiology, Quantum biology, Systems biology, Structural biology, Theoretical biology, Zoology, Ethology, Entomology, Herpetology, Ichthyology, Mammalogy, and Ornithology. Each publication will contain 10 (ten) manuscripts.
Articles 114 Documents
Study of Esterification between Oleic Acid and 2-Ethyl Hexanol by using the Microwave Method Hana Melyana Pertiwi Manurung; Juliati Br. Tarigan; Cut Fatimah Zuhra
International Journal of Ecophysiology Vol. 5 No. 2 (2023): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v5i2.13601

Abstract

Oleic acid is an unsaturated fatty acid, has a rancid odor and the main component of palm oil. To increase the value of oleic acid which has a C18 chain, it has the potential as a raw material for making long chain fatty acid esters. This fatty acid ester from vegetable oil is an emollient ester which is biodegradable which was synthesized with 2-ethyl hexanol using the Microwave method. In the last ten years, the microwave method has been widely used in organic synthesis. This esterification reaction was carried out using a modified home microwave by making a hole on top as a place for the ball cooler equipped with a stirrer, and using an acid catalyst. Characteristics of long chain fatty acid esters will be tested by FTIR and GC-MS. FTIR test results showed absorption of specific functional groups, while GC-MS was able to show the presence of long chain fatty acid ester compounds.
Antioxidant Activity Assay of Eucalyptus pellita Leaf Extract Sovia Lenny; Murni Suryani Lumbantoruan; Helmina Br. Sembiring
International Journal of Ecophysiology Vol. 5 No. 2 (2023): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v5i2.13715

Abstract

In pharmacy, eucalyptus leaves are used for various pharmacological activities because they contain phenolic compounds. This study aims to detect phytochemical compounds and test the antioxidant activity of Eucalyptus pellita leaf extract. The dry powder of E. pellita leaves (1900 g) was macerated first with methanol solvent. The concentrated methanol extract was then subjected to partition extraction with n - hexane solvent. The methanol layer was concentrated and then partitioned with ethyl acetate solvent. Methanol extract was obtained as much as 176.75 g (9,30%), n-hexane extract 13.77 g (0.72%), and ethyl acetate extract 27.93g (1.47%). The three extracts were subjected to phytochemical screening, methanol extract and ethyl acetate extract were positive for flavonoids. These three extracts did not contain alkaloids but were positive for tannins and saponins. Antioxidant activity was tested using the DPPH (1,1 diphenyl-2-picrylhydrazyl) method with UV-vis spectrophotometer (max wavelength 517 nm). Sample concentration variations were 12.5; 25; 50; 100; and 200 ppm. Ethyl acetate extract, methanol extract and n - hexane extract have antioxidant activity with IC50 values of 6.811; 17.923; and 31.109 µg/mL, respectively. This shows that E. pellita leaf extract has very strong antioxidant activity and ethyl acetate extract has more antioxidant activity.
PLASMA β-SECRETASE1 (BACE1) LEVELS AS MARKER OF COGNITIVE FUNCTION DECLINE IN ELDERLY Syahfira A Syahna; Muhammad Ichwan; Nuraiza Meutia; Jelita Siregar; Zulham Yamamoto
International Journal of Ecophysiology Vol. 5 No. 2 (2023): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v5i2.14129

Abstract

BACE1 which forms amyloid plaques consisting of amyloid β peptides is a typical neuropathological lesion in the brain of Alzheimer's disease. Many studies have shown that β-amyloid is central to the pathophysiology of Alzheimer's disease and may play an early role in neurodegenerative disorders. The BACE1 enzyme forms amyloid β plaques. The BACE1 protein is detectable in plasma and its levels are significantly increased in patients with mild cognitive impairment and future Alzheimer's. This Aβ peptide accumulates into senile plaques causing the characteristics of Alzheimer's disease, can cause neuronal death and cognitive decline
Potential of Rhizophora apiculata Blume. in Phytoremediation of Heavy Metals Pb and Cu in the Mangrove Forest Nature Reserve East Coast, Alang-Alang Village, Tanjung Jabung Timur, Jambi Juswardi; Septiantika; Singgih Triwardana; Endri Junaidi; Sarno
International Journal of Ecophysiology Vol. 5 No. 2 (2023): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v5i2.14130

Abstract

The Mangrove Forest Nature Reserve East Coast (CAHBPT) in Jambi Province has functions, one of which is to improve water quality by absorbing dangerous heavy metals such as Pb and Cu which come from various human activities around the waters. This absorption can be done by using hyperaccumulator plants such as Rhizophora apiculata Blume. This study aims to determine the potential and mechanism of R. apiculata in the phytoremediation of heavy metals Pb and Cu in the CAHBPT area, Alang-Alang Village, Tanjung Jabung Timur Regency, Jambi Province. Sampling was carried out using the purposive sampling method at three stations. The calculation of the Bioconcentration Factor (BCF) aims to determine the potential of R. apiculata in phytoremediation Pb and Cu metals, as well as the calculation of the Translocation Factor (TF) to determine the phytoremediation mechanism of R. apiculata. The results of this research found that the accumulation of Pb and Cu metals in sediments ranged from 11.04-12.36 mg/kg and 7.93-9.08 mg/kg. The accumulation of Pb and Cu metals in the roots of R. apiculata ranges from 2.34-2.65 mg/kg and 1.56-2.93 mg/kg. The accumulation of Pb and Cu metals in the shoots of R. apiculata ranged from 2.77-3.16 mg/kg and 0.61-1.05 mg/kg. The phytoremediation potential of R. apiculata at the research site is included in the excluder category or plants still limit the accumulation of heavy metals entering the body (BCF<1). R. apiculata at the research site translocated Pb metal using a phytoextraction mechanism (TF>1) and Cu metal using a phytostabilization mechanism (TF<1).
WATER QUALITY PLAYS AN IMPORTANT ROLE IN THE SOCIO-ECONOMIC CONDITION OF THE LOCAL COMMUNITY: A STUDY ON THE KUSHIARA RIVER Monjur Morshed; Abdullah Al Fatta; Binay Kumar Chakraborty; Tanvir Rahman
International Journal of Ecophysiology Vol. 6 No. 1 (2024): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v6i1.13644

Abstract

In Bangladesh around 7.5% of the fish is harvested from the rivers, being one of the main sources of fish in the country. The water quality of the river must be within standard values to maintain aquatic biodiversity. In this study, water quality, available spaces for fish, and socio-economic status of fishermen were analyzed to find their relationships in Kushiara River, Fenchuganj, Sylhet. Samples of water quality and fish species were collected from August 2017 to September 2021. At the same time, fishermen were surveyed to find out their economic status. The water quality analysis showed all the parameters analyzed (pH, Dissolved Oxygen (DO), Biochemical Oxygen Demand (BOD), Chemical Oxygen Demand (COD) and Total Dissolved Solid (TDS)) are within the range of international and Bangladesh standards for surface water. The pH, DO, BOD, COD, TDS was respectively 7.1 - 7.99, 5.5 mg/l to 8.4 mg/l, 1 to 4.6 mg/l, 17 to 32 mg/l, 30 to 70 mg/l. Where the local standard is 6.5 - 8.5, more than 5 mg/l, less than 6 mg/l, 17 to 32 mg/l for pH, DO and BOD. The international standard is less than 34.2 mg/l. and 30 to 70 mg/l for COD and TDS in that order. A total of 40 species of fish are recorded in 2017 and 49 in 2021. The average income of a fisherman was 3 USD to 15 USD in the off pick season (December- February), and 7 USD to 30 USD in the peak season (September-November). The fish merchant's daily income was 4 USD to 20 USD in the off-peak season and 7 USD to 30 USD in the peak season. It is concluded that the water quality was adequate for fish diversity and to sustain the socioeconomic condition of the fishermen and fish traders in the Kushiara River.
Plasma Sirt-1 Level in Various Frailty Degree in Elderly Outpatients at Prof. Chairudin P. Lubis Hospital, Medan Fadhilah Hayati; Dedi Ardinata; Nuraiza Meutia; Ririe Fachrina Malisie; Muhammad Ichwan
International Journal of Ecophysiology Vol. 5 No. 2 (2023): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v5i2.13681

Abstract

Frailty is a physical aging syndrome characterized by health vulnerability. Diagnosis is established incorrectly based on three or more of the five criteria: weakness, decreased walking speed, fatigue, decreased physical activity, and weight loss. Sirtuin 1 plays a role in weakness, particularly in the elderly, acting as a protective factor during weakness, and its activation could provide a novel therapeutic approach. However, research in this area is still very limited. A cross-sectional method with observation or measurement of study subjects was employed in this research, involving a total of 118 elderly subjects selected through non-probability sampling. Pearson correlation test indicates a relationship between the polymorphism genotype (rs2273773) in the SIRT1 gene and the frailty scale (p-value < 0.05), while no relationship was found between plasma SIRT1 levels and the frailty scale (p-value > 0.05). Furthermore, the F-test reveals a significant simultaneous relationship between the polymorphism genotype (rs2273773) and plasma SIRT1 levels with frailty (p-value < 0.05).
Conflict Mitigation Practices and Conservation Awareness of Orangutans: A Case Study from Tangkahan Ecotourism, Leuser Ecosystem, Indonesia Rahmadi Sitompul; Kaniwa Berliani; Stanislav Lhota
International Journal of Ecophysiology Vol. 6 No. 1 (2024): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v6i1.14274

Abstract

Killing orangutans in human-orangutan conflicts threatens their populations. Individuals with high conservation awareness tend to tolerate orangutans' crop foraging. In our study in Tangkahan ecotourism, Leuser Ecosystem, Indonesia, we examined local community mitigation methods and their understanding of orangutan conservation. We utilized a convenience sampling method for this study, primarily serving as a pilot study to test the questionnaire we had designed. This questionnaire consisted of open-ended questions used in semi-structured interviews. We conducted interviews with 16 respondents, all of whom willingly participated and allowed us to record their responses. Our findings revealed that the most commonly employed mitigation methods by the local community were the use of firecrackers and traditional crop guarding. Notably, these methods were non-lethal in nature, which aligns with the respondents' overall conservation awareness. All participants demonstrated knowledge of the protected status of orangutans, and some provided further insights into their rarity, endangerment, population decline, habitat degradation, and endemism. Their positive attitude likely stems from the impact of ecotourism.
Genetic Diversity of Durian (Durio zibethinus Murr.) from North and South Nias using Simple Sequence Repeat (SSR) Ndruru, Indah Fiyar; Saleha Hannum; Suci Rahayu
International Journal of Ecophysiology Vol. 5 No. 2 (2023): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v5i2.14314

Abstract

Durian is a tropical fruit that has economic value for Nias Island especially in North and South Nias. Anthropogenic activity already occured in Nias and caused disturbance resulting in destruction and extinction of various durian. The aim of the research was to analyzed the genetic diversity of Durian from North and South Nias using SSR primers namely: Dz844, DzGCCG01, DzGCAG01, and DzMTb021. Total DNA was successfully isolated from 20 accessions. The DNA was successfully amplified resulting in DNA alleles sizing from 170-1100 bp. All primers showed 33 alleles with 28 polymorphic bands. The DNA profile were further analyzed with Ntsys which showed that 20 accession has coefficient of similarity 0.66-0.94 and clustered into nine groups at the similarity coefficient of 0.80. The research showed that the ninth accession of durian from North and South Nias has a high genetic diversity.
Antimicrobial Properties of Pliek U as Traditional Acehnese Fermented Spices Fauzi Satria; Tri Widyawati; Taufik Sungkar
International Journal of Ecophysiology Vol. 6 No. 1 (2024): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v6i1.15987

Abstract

The high prevalence of antimicrobial resistance globally has increased the burden of disease. The phenomenon demands urgency to explore new antimicrobial drugs, one of which is sourced from natural ingredient, spices. Pliek U, as one of the spices traditionally processed by Acehnese, has attracted researchers to explore its potential source for antimicrobial substances. The objective of this literature review is to explore the characteristic, production, chemical composition, and antimicrobial mechanism of Pliek U. A literature search was carried out on PubMed, Science Direct, Springer Link, and Google Scholar using the keywords "Pliek U”, “Coconut Flesh”, and “Antimicrobial”. The articles obtained were then screened based on predetermined criteria. The results of the analysis were displayed in tabular and narrative form. The final result was 8 main articles and 10 additional articles after screening 65 articles obtained from the database. Pliek U powder is traditionally produced and has unique characteristics that make it easy to recognize. Pliek U mechanism of action based on the chemical composition and the role of lactic acid bacteria in the fermentation process. Analysis shows that Pliek U is a promising antimicrobial source, so it needs to be researched and developed further in the pre-clinical to clinical phases.
Moringa oleifera Leaf Extract and (Amorphophallus muelleri Blume.) Glucomannan Effects on Obese White Rat Feed Intake and Body Weight Wati, Dini Prastyo; Endang Setyaningsih
International Journal of Ecophysiology Vol. 6 No. 1 (2024): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v6i1.15990

Abstract

Obesity significantly raises the rates of illness and death in humans due to its association with several health conditions such as cardiovascular disease, hypertension, hypercholesterolemia, type 2 diabetes mellitus, osteoporosis, depression, breast cancer, and colon cancer. This study aims to determine the effect of Moringa oleifera leaf extract and glucomannan (Amorphophallus muelleri Blume.) on feed intake and body weight of obese white rats. This study used an experimental method with a pretest-posttest-only control grub design using 24 white male rats of the Wistar strain aged 8 weeks which were divided into 2 control groups, namely positive(K1) and negative(K2) and six treatment groups with extract doses Moringa oleifera leaves and glucomannan (Amorphophallus muelleri Blume.) 100mg/kgBW:100mg/kgBW(K3), 80mg/kgBW:120mg/kgBW(K4), 120mg/kgBW: 80mg/kgBW(K5), 50mg/kgBW:50mg/kgBW(K6), 40mg/kgBW:60mg/kgBW(K7), and 60mg/kgBW:40mg/kgBW(K8). Data analysis on body weight and feed intake used the SPSS ANOVA test and paired T-test. The results of the paired T-test (p<0.05) showed that Moringa oleifera leaf extract and glucomannan (Amorphophallus muelleri Blume.) significantly reduced body weight and feed intake. In conclusion, administration of Moringa oleifera leaf extract and glucomannan (Amorphophallus muelleri Blume.) in group K4 (80 mg/kgBW Moringa oleifera leaf extract: 120 mg/kgBW glucomannan Amorphophallus muelleri Blume) can reduce feed intake (4.29 g) and body weight (36.67 g) effectively.

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