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Andika Aliviameita
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Medicra (Journal of Medical Laboratory Science/Technology)
Published by Universitas Muhammadiyah Sidoarjo
ISSN : 25807730     EISSN : 25807730     DOI : https://doi.org/10.21070/medicra
Core Subject : Health,
Health Professions Public Health
Focus : to facilitate scholar, researchers, and lecturers for publishing the original articles of review articles. Scope : Medicra publishes research articles in the field of “medical laboratory (science/technology)” with the following scope: Clinic Chemical Hematology Microbiology Parasitology Immunology Food and beverage analysis Chemical Molecular Diagnostics Toxicology Cytology Histology Epidemiology Laboratory Management Laboratory Quality Control
Arjuna Subject : Profesi Kesehatan - Teknologi Laboratorium Medis
Articles 129 Documents
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Analysis of The Presence of Pathogen Bacteria in Rectal Swab of Food Handler at The Yogyakarta Health and Calibration Laboratory: Analisis Keberadaan Bakteri Patogen pada Rectal Swab Penjamah Makanan di Balai Laboratorium Kesehatan dan Kalibrasi Yogyakarta Ratna Kusumaningtyas; Dhiah Novalina; Irfani, Farida Noor
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 7 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v7i2.1760

Abstract

Food handlers are workers who are responsible for handling food from preparation to serving. In accordance with the Regulation of the Minister of Health of the Republic of Indonesia Number 1096/MENKES/PER/VI/2011, food handlers must be checked periodically every six months by carrying out anal swabs to find out whether the food handler is free. of pathogenic bacteria and act as carriers or not. This study aims to find out whether food handlers who work at Food Management Places (TPM) in Yogyakarta act as careers or not through identifying pathogenic bacteria in rectal swab samples. The type of research used was descriptive qualitative with a cross-sectional approach by taking data at BLKK Yogyakarta from January to December 2023. The sample in this study amounted to 86 data using a purposive sampling technique based on inclusion and exclusion criteria. Data were analyzed for frequency distribution and Chi-Square and Odds Ratio statistical tests were carried out. The results of the study showed that the examination was dominated by the TPM type, namely catering class B (hospital) as many as 4 (40,0%) applicants, the early adult age group (18-40 years) as many as 73 (84,9%) and gender men were 44 (51,2%) food handlers. The results of the rectal swab examination showed positive Escherichia coli bacteria (carrier) in 33 (38,4%) food handlers and there was a significant relationship between the results of the examination for pathogenic bacteria and TPM sanitation (p-value 0,023), but there was no significant relationship between results of examination of pathogenic bacteria with age (p-value 0,531) and gender (p-value 0,695).
Protein Profile of Cod Fish (Euthynnus affinis) Preserved with Pineapple Peel Vinegar (Ananas comosus)-NaCl Formulation Based on Soaking Variations: Profil Protein Ikan Tongkol (Euthynnus affinis) Yang Di Awetkan Dengan Formulasi Cuka Kulit Nanas (Ananas comosus) Dan NaCl Berdasarkan Variasi Perendaman Mardiyah, Siti; Jannah, Faiqotul; Kartikorini, Nastiti; Supatmi, Supatmi
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 7 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v7i2.1762

Abstract

Fish is a food source that is easily damaged. The quality of fish is easily reduced because the water and protein content in fish is quite high so that it rots easily. Therefore, fish require preservation that can maintain the quality of fish, some fishermen usually use formalin as a preservative to preserve fish, but formalin is not allowed in food ingredients because formalin is harmful to health. The use of natural preservatives is an alternative choice for preserving fish. Pineapple skin vinegar is one of the natural preservatives that can be used because it contains acetic acid which functions as an antimicrobial that prevents the growth of bacteria in fish. The purpose of this study was to analyze the description of the protein content of Tuna fish (Euthynnusaffinis) preserved with pineapple skin vinegar (AnanasComosus) and NaCl formulations based on soaking variations. This type of research is descriptive research conducted by grouping fish to determine the protein content of fish incubated for 12 hours in each group. The results showed that 15-minute soaking got an average value of 9.3504%, while 20-minute soaking got an average value of 17.6214%. The conclusion is that the soaking time of pineapple skin vinegar and NaCl got different average values.
Prevalence of Human Immunodeficiency Virus (HIV) Antibody Detection in Men Who Have Sex with Men (MSM): Prevalensi Deteksi Antibodi Human Immunodeficiency Virus (HIV) Pada Kelompok Lelaki Seks Lelaki (LSL) Haq, Fhasya Algina Hawatul; Amelia, Ria; Sari, Elfira Maya; Luhulima, Danny Ernest Jonas
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 7 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v7i2.1764

Abstract

Human Immunodeficiency Virus (HIV) infection is one of the infectious infections caused by HIV that attacks the lymphocytes T tipe CD4 and can cause a decrease in the immune system. Male Sex Men (MSM) have a higher risk of HIV infection due to MSM behavior, such as having direct anal sex without using condoms or lubricant products and are more likely to change sex partners frequently. This study aims to find out the results of rapid testing of HIV antibodies on MSM in Rawalumbu and Jaka Mulya urban village. This research uses cross sectional research design, its type of research is descriptive with selection and data collection purposively sampling that carried out in February – June 2024 in Rawalumbu and Jaka Mulya urban village. Thirty-five respondents were collected. The result from a rapid test of early HIV antibodies with rapid Reagen 1 (R1) in 35 respondents, 6 respondents (17%) were reactive and 29 respondents (83%) were non-reactive. HIV antibody reactive results is 6 respondents (17%) of total 35 respondents, the most reactive outcomes in the age category 26 – 36 years.
Correlation Isocitrate Dehydrogenase Level and Triglyceride Level in Rats Stimulated with Ethanol Extract of Moringa Leaf: Hubungan Kadar Isositrat Dehidrogenase dengan Kadar Trigliserida pada Tikus yang Distimulasi dengan Ekstrak Etanol Daun Kelor Fitriana Sari, Devi; Wulandari, Devyana Dyah; Wardany, Nadya Ika; Baskara, Muhamad Damar; Nadzarillah, Najmatul Jannah
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 7 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v7i2.1768

Abstract

Food substances are oxidized through mitochondria to produce chemical energy in the form of adenosine triphosphate (ATP), which is used as energy. The Krebs cycle uses the energy produced by the body to make adenosine triphosphate. A class of enzymes known as dehydrogenases including isocitrate dehydrogenase (IDH) is responsible for electron transport from substrate to electron receiver. In addition, IDH is involved in various cellular processes, including lipogenesis, which is part of lipid metabolism. This study aimed to investigate the relationship between triglyceride (TG) levels and mitochondrial IDH enzyme activity with respect to taking ethanol extract of Moringa oleifera leaves. This type of research is experimental with a control group design. The samples in this study were 20 white rats divided into 5 treatment groups, namely Negative Control (K-) rats with normal conditions, Positive Control (K+) rats with tired conditions, Standard Group (STD) rats with creatinine drug induction, Treatment 1 (P1) rats given 250 mg/kgBB dose of Moringa oliefera leaf extract, Treatment 2 (P2) rats given 500 mg/kgBB dose of Moringa Oliefera leaf extract. The results of statistical analysis of the correlation test p value 0.147 ≥0.05 can be concluded that there is no relationship between IDH enzymes and TG.
Factors Contributing to the Failure of In Vitro Fertilization (IVF): A Review of Male, Female, and Laboratory-Related Causes Abdolhussein M, Mudhafar
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 8 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v8i1.1771

Abstract

Infertility is big problem with some couples, infertility is an inability to get pregnancy and live birth after one year of marriage. There are many causes for this problem. In vitro fertilization (IVF) is one of the process to treat infertility. In vitro fertilization is includes induction of the ovaries to produce numerous oocytes, than fertilize the oocytes and development of the embryo, finally transfer the embryo. The most important reasons for repeated failure in vitro fertilization (IVF) cycle are related to the male characteristics, such as low semen concentration low sperm motility and morphology of sperm, there is a relationship between sperm quality and IVF outcome. Most of the maternal factors that contribution in decrease implantation and IVF cycle are uterine anomalies, adhesions, septa, and many more. Other factors such as body mass index (BMI), and smoking status for failure IVF. In this study review some of the causes of failure In vitro fertilization.
Influence of Hydrocortisone on Blood Profile, Total Protein, And Glucose in Female Rabbits Ali, Wasfi Dhahir Abid
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 8 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v8i1.1783

Abstract

The purpose of this study is to examine how hydrocortisone affects a few blood parameters in female rabbits. Ten local rabbits were split into two equal and random groups. As a control, the first group was employed. The second group received daily intramuscular injections of hydrocortisone at a dose of 0.1 mg/kg B.W. Blood serum was collected every day from the first day and evaluated for total cholesterol, HDL (high-density lipoprotein), LDL (low-density lipoprotein), TG (triglycerides), and total protein after five weeks. The findings demonstrated that hydrocortisone reduced total protein and cholesterol.
Effectiveness of Mangrove Kateng Leaf Extract (Avicennia lanata Ridl.) as a Natural Preservative for Fresh Vannamei Shrimp Meat (Litopenaeus vannamei): Efektivitas Ekstrak Daun Kateng Mangrove (Avicennia lanata Ridl.) sebagai Pengawet Alami Daging Segar Udang Vannamei (Litopenaeus vannamei) Pramudya, Arkan Setia; Yachya, Arif; Suparman, Suparman
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 8 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v8i1.1781

Abstract

Vannamei shrimp (Litopenaeus vannamei) is a mainstay export fishery product. Its meat is rich in protein and fat, but the quality is easy to reduce due to decay over storage time. Decay occurs due to bacterial activity and oxidation. The freezing preservation method requires relatively expensive costs, so it often uses hazardous materials for substitution, such as formalin as a preservative. Therefore, it is necessary to research the effectiveness of natural materials sourced from plant organs as relatively safe preservatives. One of the plants is Kateng (Avicennia lanata), whose leaves are rich in secondary metabolite compounds that inhibit growth and kill bacteria. This study aims to determine the effectiveness of A. lanata water extract as a natural preservative for fresh Vannamei shrimp meat. The research was an experimental laboratory study using a completely randomized design with three repetitions. The concentrations of the A. lanata water extract solution tested were 0, 25, 50, 75, and 100% (w/v). Variations in the storing time of shrimp meat after being soaked in the test extract solution were 2 and 4 hours. The storage was at room temperature. The parameters of shrimp meat quality observed at the end of the storage period included total bacterial population, hydrogen sulfide gas (H2S) production, acidity level (pH), and trimethylamine (TMA) content. The results showed that the quality of fresh Vannamei shrimp meat depends on various concentrations of A. lanata water extract solution (0-100% w/v) and storage periods (2 and 4 hours). Water extract of A. lanata leaves at a concentration of 75% (w/v) with 2 hours of storage is the optimal concentration and storage time to preserve fresh L. vannamei shrimp meat naturally.
Sex Determination Based on Finger Bones: A Systematic Review: Penentuan Jenis Kelamin Berdasarkan Tulang Jari: Tinjauan Sistematis ur Rahman, Ateeq; Kristianto, Sonny; Widodo, Wimbuh Tri; Rayditya Milanio, Roderikus; ur Rahman, Anees; Setiawardani, Alvina; ul Haq, Ihtisham
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 8 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v8i1.1754

Abstract

Sex determination is a crucial step in forensic investigations, particularly when skeletal remains are incomplete. This study aims to evaluate the accuracy of using finger bones as indicators of sex through a systematic review approach. The literature selection followed PRISMA guidelines, with data retrieved from PubMed and Google Scholar using relevant keywords. Out of 95 identified articles, only 10 met the inclusion criteria and were further analyzed. Findings indicate that the length and proportion of finger bones—especially the ring and little fingers—differ significantly between males and females. Classification accuracy based on phalangeal and metacarpal measurements ranged from 80% to 94%. Additionally, hormonal influences such as testosterone contribute to these morphological differences. These results support the effectiveness of finger bones as an alternative method for sex estimation, particularly when pelvis or skull bones are unavailable in forensic contexts.
Assessment of Nitrate, Nitrite, and Ammonia Levels In Palu Bay and Its Impact on Health: Analisis Kandungan Nitrat, Nitrit dan Amonia di Perairan Teluk Palu dan Dampaknya Bagi Kesehatan Paundanan, Matius; Hikmah, Sitti Ainun
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 8 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v8i1.1775

Abstract

Water pollution due to nitrate, nitrite, and ammonia content has become a significant issue in Indonesian waters, including Palu Bay, which has the potential to affect water quality and human health. This study aims to analyze the levels of nitrate, nitrite, and ammonia in Palu Bay waters and their impacts on human health. Water samples were collected from 10 observation stations in Palu Bay and then brought to the laboratory for analysis. The laboratory results were compared with the Water Quality Standards as set by the Minister of Environment Regulation of the Republic of Indonesia No. 51 of 2004 concerning Marine Water Quality Standards for Marine Biota. The results of the study show that nitrate concentrations varied between 0.326 mg/l and 1.199 mg/l, exceeding the established standard of 0.008 mg/l. Meanwhile, nitrite was found at very low levels (<0.003 mg/l) and was only slightly detected at a few stations, while ammonia concentrations ranged from <0.03 mg/l to 0.06 mg/l, still within the standard limit of 0.3 mg/l. High nitrate levels have the potential to cause water pollution and negatively impact aquatic ecosystems as well as human health, particularly through respiratory and digestive issues, and pose a risk to infants consuming nitrate-contaminated water. Although nitrite and ammonia levels were not significant, the presence of these compounds still requires monitoring. This study suggests the need for better water quality management to prevent long-term health impacts and damage to aquatic ecosystems. 
Journal Review: Potential of Gotu Kola Leaves (Centella asiatica) as Antibacterial Against Staphylococcus aureus: Jurnal Review: Potensi Daun Pegagan (Centella Asiatica) Sebagai Antibakteri Terhadap Staphylococcus aureus Ernanda, Hafid; Mukhtar, Diniwati; Purwaningsih, Endang; Hakim, Jasir
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 8 No. 2 (2025): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v8i1.1779

Abstract

Herbal substances used worldwide include pegagan (Centella asiatica). Triterpenoids and saponins found in this plant have various medicinal benefits. Staphylococcus aureus has long been the most common cause of diseases present in society globally. The aimof this study is to outline the results of a literature review on the effectiveness of pegagan leaves (Centella asiatica). A literature review is the method used in this research. The selected journals are sourced from several national journal databases, resulting in 10 articles that meet the inclusion and exclusion criteria. The review findings indicate that pegagan leaves possess antibacterial activity against Staphylococcus aureus. Pegagan leaves have the potential to act as an antibacterial agent against Staphylococcus aureus with an effective extract concentration, specifically a high concentration of pegagan leaf extract.

Page 12 of 13 | Total Record : 129

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