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Andika Aliviameita
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Medicra (Journal of Medical Laboratory Science/Technology)
Published by Universitas Muhammadiyah Sidoarjo
ISSN : 25807730     EISSN : 25807730     DOI : https://doi.org/10.21070/medicra
Core Subject : Health,
Health Professions Public Health
Focus : to facilitate scholar, researchers, and lecturers for publishing the original articles of review articles. Scope : Medicra publishes research articles in the field of “medical laboratory (science/technology)” with the following scope: Clinic Chemical Hematology Microbiology Parasitology Immunology Food and beverage analysis Chemical Molecular Diagnostics Toxicology Cytology Histology Epidemiology Laboratory Management Laboratory Quality Control
Arjuna Subject : Profesi Kesehatan - Teknologi Laboratorium Medis
Articles 129 Documents
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Acute Toxicity Test Against Mice (Mus Musculus) On The Lempuyang Gajah Extract (Zingiber Zerumbet (L.) Roscoe Ex Sm.) With Sgot Sgpt Parameters: Uji Toksisitas Akut Terhadap Mencit (Mus Musculus) Pada Ekstrak Lempuyang Gajah (Zingiber Zerumbet (L.) Roscoe Ex Sm.) Dengan Parameter SGOT SGPT Sofi Rahayu, Bella; Rohmah, Jamilatur; Rini, Chylen Setiyo; Puspitasari
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 7 No. 1 (2024): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v7i1.1656

Abstract

Lempuyang Gajah (Zingiber zerumbet (L.) Roscoe ex Sm) is a medicinal plant that has many benefits in the medicinal industry. Useful as a tonic, external medicine, anti-seizure and appetite enhancer. This study aims to determine the toxicity of the lempuyang gajah. This research uses laboratory experimental methods. The lempuyang gajah plant was obtained in the village of Terungkulon, Krian. The initial stage was the administration of lempuyang gajah extract with various doses of 4000, 5000 and 6000 mg/kg BB orally, consisting of 5 treatment groups. Parameters observed, changes in toxic symptoms, macroscopic examination and parameters of SGOT, SGPT. The results were analyzed using the One Way ANOVA test. The results of the study after giving the extract did not cause death so it was included in the non-toxic category, there were several symptoms such as weakness and seizures. The levels of SGOT, SGPT showed normal average results, statistically there was no effect (p > 0.05). Macroscopic results showed no changes or abnormalities in the liver. So that the ethanol extract of lempuyang gajah can be said to be safe for humans.
Relationship Between Blood Glucose Levels With Albumin and HDL (High-Density Lipoprotein) Levels In Diabetic Ulcers: Hubungan Kadar Glukosa Darah Terhadap Kadar Albumin dan Kadar Kolesterol HDL (High-Density Lipoprotein) Pada Pasien Ulkus Diabetikum Ilmi, Isyfa'ul; Puspitasari, Puspitasari
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 6 No. 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v6i2.1658

Abstract

Diabetes mellitus is a disease caused by disorders of the body’s metabolism, because blood glucose levels have a increased or hyperglycemia. According to the IDF in 2021 DM sufferers have increased from 463 million people (9.3%) to 537 million people (10.5%) in 2021. The purpose of this study was to determine the relationship between blood glucose levels and blood albumin and HDL cholesterol in diabetic ulcer patients. The design of this study was a cross-sectional method, in 30 respondents with diabetes mellitus with diabetic ulcers who were undergoing treatment at the Sidoarjo Luka Home. Examination of glucose, albumin and HDL cholesterol was carried out using the enzymatic method using a photometer, on 28 May – 20 June 2022. The results of the study were analyzed using Pearson’s Parametric Correlation statistics. Blood glucose levels with blood albumin levels have a strong correlation with a negative correlation direction (r = -0.470 p= 0.009), while blood glucose levels with HDL (High-Density Lipoprotein) cholesterol levels have a weak correlation with a negative correlation direction (r=-0.375 p=0.041).
Comparation of n-Heksan and Etanol in Bawang Dayak (Elutherine palmifolia L. Merr) Extraction for Inhibiting Pseudomonas aeruginosa: Penggunaan n-Heksan dan Etanol dalam Ekstraksi Bawang Dayak (Elutherine palmifolia L. Merr) Terhadap Kemampuan Daya Hambat Pseudomonas aeruginosa Putri, Ananda Ghufron Yuana; Prayekti, Endah
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 6 No. 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v6i2.1662

Abstract

Pseudomonas aeruginosa is one of the bacteria that causes nosocomial infections. The incidence of nosocomial infections caused by Pseudomonas aeruginosa is around 10-15%. Nosocomial infections caused by these bacteria are increasingly difficult to treat. This happens because more and more strains are resistant to several antibiotics (Multidrug Resistance), so the selection of antibiotics against Pseudomonas aeruginosa is very difficult. This study aims to determine and analyze the effect of using polar and nonpolar solvents on Dayak onion bulb extract on the inhibitory ability of Pseudomonas aeruginosa. The method used in this study was Kirby-Bauer disk diffusion using 8 sample and 5 replication with assay solvent 96% ethanol and n-hexane extract of Dayak onion bulbs (Eleutherine palmifolia L. Merr) with concentration variations of 75%, 80%, and 85%. Positive control used ciprofloxacin 5 µg and positive control DMSO 10%. The results showed that on phytochemical screening of solvent ethanol 96% contained flavonoids and n-hexane contained triterpenoids. Ethanol 96% solvent obtained a higher presentase yield than n-heksan solvents and the highest inhibition zone diameter was 85% concentration in 96% ethanol solvent. The results of statistical analysis with Mann Whitney test showed a significant difference between the treatment groups (p<0.05).
The Effect Of Serum StorageTime On Room Temperature On Creatinine And Uric Acid: Pengaruh Lama Penyimpanan Serum Pada Suhu Ruang Terhadap Kadar Kreatinin Dan Asam Urat Lestari, Dzulia; Aliviameita, Andika
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 6 No. 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v6i2.1675

Abstract

The examination parameters used as a detection of impaired kidney function are ureum, creatinine, and uric acid. The purpose of this study was to determine the effect of serum storage duration at room temperature on creatinine and uric acid levels. The study was conducted by experimental method using 32 serum samples. The data obtained by one wayAnova statistical analysis on creatinine examination showed a significance value of p = 0.009 (p<0.05) meaning that there was an influence of the length of serum storage on creatinine levels at room temperature, while in uric acid levels showed a significance value of p = 0.047 (p<0.05) meaning that there was an influence of serum storage duration on uric acid levels at room temperature. The conclusions on the examination of creatinine and uric acid levels had a significant effect on the delay of the treatment group of 0 hours and 24 hours.
An Overview of Serologic Test Results in Covid-19 Patients: Gambaran Hasil Pemeriksaan Serologi pada Pasien Covid-19 Kesuma, Suryanata
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 7 No. 1 (2024): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v7i1.1682

Abstract

Coronavirus Disease 2019 (Covid-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). SARS-CoV-2 protein and antibody/serology assays can be used for sero-surveillance studies and analyze the epidemiology and virology of SARS-CoV-2. This study aims to review the results of serological tests in Covid-19 patients with the parameters of IgM and IgG antibodies, C-Reactive Protein, procalcitonin, and serum ferritin through literacy studies. This research is descriptive. The study was conducted by collecting and reviewing data on the results of serological examinations in Covid-19 patients contained in articles and journals. After collecting data, 10 journals were obtained that matched the inclusion criteria set by the researcher. The conclusion of this study was that there was an increase in c-reactive protein and procalcitonin levels in Covid-19 patients, serum ferritin levels were also found to tend to increase. IgM antibodies were found to increase earlier than IgG antibodies, but their levels decreased more quickly. An increase in IgG antibodies occurs around the second week after the onset of symptoms.
The Relationship Of Lead (Pb) Levels With The Number Of Blood Platelets At SPBU Officers : Hubungan Kadar Timbal (Pb) Dengan Jumlah Trombosit Darah Pada Petugas SPBU Putri, Mardiana Prasetyani; Purnadianti, Mely
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 6 No. 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v6i2.1705

Abstract

Lead (Pb) is the main pollutant in the environment. Lead in fuel is an additive that is added to a gasoline mixture with the aim of increasing combustion so that vehicle performance increases. Lead is a type of heavy metal that can cause poisoning. Lead is easily absorbed in the body and can accumulate in human tissues. Lead can enter the human body through the respiratory system, orally, or through the skin surface. High lead levels in the blood can cause low platelets. This is because lead can interfere with the heme system in the blood, causing anemia. The aim of the study was to determine the relationship between lead (Pb) levels and blood platelet counts at gas stations in Mekikis Village. The research design in this study used a cross sectional approach. The research sample consisted of 10 gas station attendants. The sampling technique used was purposive sampling. Based on the examination, the average lead and platelet levels for gas station workers were 0.4344 ppm and 293,500 /UL respectively. Based on the results of the Spearman correlation test, a significant value of 0.391 was obtained where the sign value was > 0.05, which means that there is no relationship between lead levels and the number of platelets in the blood of Mekikis Village gas station attendants.
Tuberculosis Testis In Middle-Aged Male As A Rare Case Of Genitourinary Tuberculosis: A Case Report: Tuberkulosis Testis Pada Pria Dewasa Muda Sebagai Kasus Langka Tuberkulosis Genitourinari: Laporan Studi Kasus Surya, Prima Ardiansah; Faadilah, Ashifa Hasna; Indarjadi, Ignasius; Wirjopranoto, Soetojo; Jamhari, Muhammad Arif Hakim; Azmi, Yufi Aulia
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 6 No. 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v6i2.1720

Abstract

Introduction: Testicular tuberculosis is a very rare type of urogenital TB. Case Presentation: A 36 year old man came to the emergency room because of pain in the right testicle accompanied by swelling and discharge. Orchiectomy on the dextra testis was continued with treatment using category 1 OAT for 9 months after the diagnosis was made using anatomic pathology examination. Discussion: The physical examination needs to be done carefully because most general practitioners consider testicular enlargement to be a malignancy. Urogenital tuberculosis requires 6 months of treatment and 9 months of treatment in patients with certain conditions. Conclusion: Prompt and precise diagnosis if testicular TB is necesssary to prevent infertility, the most common complication
The Effect of Green Grape Extract on Serum Triglyceride Levels in Rats: Pengaruh Pemberian Ekstrak Anggur Hijau terhadap Kadar Triglierida Serum pada Tikus Bekti, Heri Setiyo; Dewi, Ni Nyoman Astika; Rinawati, Luh Putu; Dewi, Ni Wayan Rika Kumara; Hadi, Mochammad Choirul
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 7 No. 1 (2024): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v7i1.1721

Abstract

Cardiovascular disease, one of which is coronary heart disease (CHD) is the main cause of death and morbidity caused by blockages in the coronary arteries (atherosclerosis). Elevated serum triglyceride levels can encourage the formation of atherosclerosis. Statins are the drugs most commonly used to lower triglyceride levels but have side effects, so new treatment are needed. Grapes are fruits that has many bioactive compounds such as proanthocyanidins and resveratrol which are believed to reduce triglyceride levels in serum. The purpose of this study was to determine the effect of green grape extract (Vitis vinifera) on triglyceride levels in male Wistar rats which were divided into 5 groups, namely P0 (fed with standard feed), P1 (fed with high cholesterol and then standard feed), P2 (fed with high cholesterol and simvastatin 0.2mg/200mgBW/day), P3 (fed with high cholesterol and grape extract at a dose of 500mg/200mgBW/day), and P4 (fed with high cholesterol and 250mg/200mgBW/day grape extract). Examination of triglyceride levels was carried out using the GPO-PAP method. Data analysis was performed with Annova test followed by Bonferroni test. The statistical test results showed that there were significant differences between each treatment group. The P3 group showed a lower average triglyceride level than P4 although it was still higher than P2. This showed that administration of green grape extract has an effect on decreasing serum triglyceride levels in all.
Analysis Of Bacterial Contamination By Total Plate Number (ALT) Method In Smoked Fish At One Of The Market Traders: Analisis Cemaran Bakteri Metode Angka Lempeng Total (ALT) pada Ikan Asap di Salah Satu Pedagang Pasar Safitri, Yunita Diyah; Widodo, Wimbuh Tri; Azizah, Yunita Dwi Nur
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 6 No. 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v6i2.1723

Abstract

Bacterial contamination can come from the environment as a result of food production processes in the form of biological, chemical and foreign matter contaminants that can interfere with, harm and endanger human health. One of the problems in the processed food sector is the high level of bacterial contamination in the food served on the market. The condition of open food is also the main factor causing food to be contaminated with bacteria. The Total Plate Count (ALT) or total plate count (TPC) is an examination used to determine the number of microorganisms both bacteria and fungi using solid media with the final result being colonies. The aim of the study was to determine bacterial contamination and to determine the total plate number (ALT) of bacterial colonies in smoked fish sold at Ngemplak Market, Tulungagung. This research used a Simple Random Design (RAS) method with four treatments and 3 repetitions. The results showed that for menot fish it was 16.2 x 105 cfu/g, for tuna it was 10.5 x 105 cfu/g, for tuna it was 9.4 x 105 cfu/g, for bader fish it was 16.4 x 105 cfu/g. g, and in whitefish 20.5 x 105 cfu/g. The conclusion is that the bacterial contamination of smoked fish sold at the Ngemplak Market using the ALT method exceeds the normal limit value set by SNI 2725:2013.
Capacity of Mangrove Fruit Macerate (Sonneratia alba) as a Preservative Fresh Vannamei Shrimp (Litopenaeus vannamei) Meat: Kapasitas Maserat Buah Mangrove (Sonneratia alba) sebagai Pengawet Daging Udang Vannamei (Litopenaeus vannamei) Segar Wicaksono, Agung; Pramudya, Arkan Setia; Zaki, Ekiq Naufal; yachya, Arif
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 6 No. 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v6i2.1725

Abstract

Mangrove fruit (Sonneratia alba) is known to contain tannins. This flavonoid has antibacterial properties. It makes this fruit macerate has potential as a preservative for shrimp meat. This study aimed for determining the ability of S. alba fruit macerate to maintain the quality of vannamei shrimp meat. The study was conducted in a laboratory by exposing fresh vannamei shrimp meat to S. alba fruit macerate. Exposure was carried out by soaking shrimp meat. The concentrations of macerate used were 25, 50, 75, and 100%. The duration of soaking was 60 and 120 minutes. Bacterial population (total plate count), presence of hydrogen sulfide gas (H2S), acidity value (pH), and score of organoleptic were used as indicators of Shrimp meat quality. The tests were conducted after 24 hours of incubating shrimp meat at room temperature. The results showed the concentration of macerate and the time of soaking affected the quality of the shrimp meat. These effects were in the form of inhibition of bacterial populations, production of H2S and maintaining organoleptic properties, while the pH values ​​of all treatments were the same. Finally, the best concentration of macerate to maintain the quality of fresh vannamei shrimp meat is 100% with 60 minutes of soaking time.

Page 10 of 13 | Total Record : 129

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