Articles
GAMBARAN KADAR HEMOGLOBIN PADA PEROKOK AKTIF DI TERMINAL KAYURINGIN KOTA BEKASI
Ramadhanti, Moudy;
Amelia, Ria;
Luhulima, Danny
Jurnal Mitra Kesehatan Vol 2, No 1 (2019)
Publisher : STIKes Mitra Keluarga
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Perilaku merokok berdampak yang buruk terhadap kesehatan. Salah satu zat berbahaya dalam asap rokok yaitu karbon monoksida. Karbon monoksida yang sangat mudah berikatan dengan hemoglobin dibandingkan dengan oksigen maupun karbondioksida. Ikatan karbon monoksida dengan hemoglobin dapat beresiko terjadinya kondisi hipoksia. Jika kondisi ini dibiarkan maka dapat menyebabkan kematian sel. Penelitian ini dilakukan untuk melihat gambaran kadar hemoglobin pada perokok aktif di Terminal Kayuringin Kota Bekasi. Jenis penelitian yang dilakukan adalah penelitian deskriptif dengan menggunakan desain penelitian cross sectional. Jumlah responden sebanyak 31 perokok aktif yang diperoleh melalui wawancara dan kadar hemoglobin diperiksa dengan menggunakan alat hematology analyzer ABX Micros 60. Hasil penelitian kadar hemoglobin pada 31 responden perokok aktif diperoleh nilai rata-rata sebesar 14,5 g/dL, dengan standar deviasi 1,0942 g/dL, nilai tertinggi 16,9 g/dL dan nilai terendah 12,3 g/dL. Berdasarkan hasil tersebut dapat disimpulkan bahwa kadar hemoglobin pada 31 responden perokok aktif masih dalam kadar normal. Kadar hemoglobin normal pada perokok aktif diduga sebagai respon tubuh untuk memenuhi oksigen dan menjaga homeostatis agar metabolisme tubuh berjalan normal. Kata kunci : hematology analyzer, kadar hemoglobin, perokok aktif
FORMULATION AND PHYSICAL CHARACTERIZATION OF BLACK SOYBEAN (Glycine Max L.) VARIETY OF DETAM II TABLETS WITH DRY GRANULATION METHOD
Amelia, Ria
International Journal of Natural Science and Engineering Vol 5, No 1 (2021)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat
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DOI: 10.23887/ijnse.v5i1.33441
Black Soybeans (Glycine max L.) Detam II varieties have a higher protein content than other varieties. The high protein content in soybeans (Glycine max L.) is directly proportional to the levels of flavonoid compounds. Flavonoid compounds have been known to have potential as antioxidant compounds that can be beneficial for health. This study aims to obtain a tablet formulation of black soybean (Glycine max L.) detam II varieties . The research was conducted from February to October 2020 at the Pharmaceutical Technology Laboratory STIKes Mitra Keluarga. Preparation of black soybean (Glycine max L.) tablet of detam II variety by slugging method. Detam II black soybean tablets (Glycine max L.) were made into 5 formulas with 250 mg black soybean powder (Glycine max L.) content of detam II varieties in each formula. the differentiated variable is the tablet excipient compound in each formula. Evaluation of black soybean (Glycine max L.) tablet granules of detam II variety by testing water content,compressibility, flow time, angle of rest and tablet evaluation by testing organoleptic, weight, hardness, brittleness and disintegration time. The results showed that a formula 3, 4 and 5 are the recommended formulations for the manufacture of black soybean tablets (Glycine max L.) detam II varieties even though all formula ( F1-F5) were below the friability value requirements due to several factors. Gelatin excipient and PVP K30 for the manufacture of black soybean tablets (Glycine max L.) detam II varieties are the best choices as tablet fillers.
A sign of acute inflammation in type 2 diabetes mellitus patients in Kota Baru and Kalibaru subdistricts, Bekasi
Ria Amelia;
Neni Arshita;
Siti Nur Fajriah;
Chandra Vina Dwi Astuti;
Islamiyah Nurul Fitri
Acta Biochimica Indonesiana Vol. 2 No. 2 (2019): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology
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DOI: 10.32889/actabioina.v2i2.38
Background: During the development of chronic type 2 diabetes mellitus (T2DM), inflammatory signals are elevated which can cause microvascular damage. C-Reactive Protein (CRP) is one of acute phase proteins stimulated under inflammatory conditions and creatinine is a waste product used to measure the glomerular filtration rate (GFR). Both of these compounds are considered as biomarkers of acute kidney damage among people with T2DM. Objective: The purpose of this study was to determine relationship between CRP and creatinine levels in T2DM patients. Methods: We conducted analytic cross-sectional study in Kota Baru and Kalibaru sub-districts, Bekasi, from January until February 2019. Creatinine was measured using the jaffe method and CRP was measured using a latex agglutination technique. The correlation between CRP and creatinine was analyzed with Spearman test. Results: Spearman correlation test from 55 samples showed a weak positive correlation (r = 0.289 ; p < 0.05) between CRP levels and creatinine levels. These results indicate that high CRP levels are directly proportional to creatinine levels in the serum of T2DM patients. Creatinine and CRP levels can be used as clinical parameters as biomarker for acute microvascular damage in nephron cells that can develop into complications due to T2DM. Conclusion: There was a significant, weak positive correlation between CRP levels and creatinine levels in T2DM patients in Kota Baru and Kalibaru districts, Bekasi
Cross-Reaction Antibody Test between SARS-CoV-2 and Dengue Hemorrhagic Fever in Indonesia
Danny Luhulima;
Tri Soetowo;
Ria Amelia
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 27, No 2 (2021)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory
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DOI: 10.24293/ijcpml.v27i2.1681
Coronaviruses are a family of viruses that cause illness from the common cold to severe diseases such as Severe AcuteRespiratory Syndrome (SARS-CoV). In December 2019, forty new cases of pneumonia of unknown etiology have beenreported in Wuhan, China. The disease resembles Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and hasbeen subsequently named the 2019-novel Coronavirus Disease (COVID-19). The antibody test is a blood test that providesquantitative and qualitative detection of IgG and IgM antibodies against the SARS-CoV-2. Reported a male, 43-year oldsuffering from DHF, but the results of an IgG and IgM rapid test were COVID-19 reactive. Also, reviewed rapid tests forCOVID-19 and the results showed that only IgG was reactive. This explained that the patient already had SARS Cov-2antibodies but was not suffering from the disease. The rapid test COVID-19 IgM result was deemed to be a false positive.
Deteksi Dini Penyakit Gout Pada Lansia di Wilayah Kerja Puskesmas Kalibaru Bekasi
Ria Amelia
Dinamisia : Jurnal Pengabdian Kepada Masyarakat Vol. 5 No. 2 (2021): April 2021, Dinamisia: Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Lancang Kuning
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DOI: 10.31849/dinamisia.v5i2.4250
Gout caused by hyperuricemia is a condition of high of uric acid in the blood. The condition of hyperuricemia in elderly is related to metabolic syndrome which is caused by slow rate of the body's metabolism. This activity aims to determine a prevalence of hyperuricemia in elderly at four Posbindu as a working area of Kalibaru Health Center. Type of research is cross sectional with a simple random sampling method. The activity was carried out in August 2019. The method to measurement of uric acid levels by the strip method. The Descriptive test results showed a modus of the elderly is at the age of 65 years and the oldest at the age of 89 years. The percentage of elderly people who experience hyperuricemia based on WHO 2013 criteria as many as 8.8% from a total of 68 elderly. The conclusion of this activity indicates that 90% of elderly in the working area of the Kalibaru Helath Center have normal of uric acid levels.
Gambaran Histologi Pankreas Tikus dengan Diabetes Melitus Tipe 2 yang Diberikan Tablet Kedelai Detam II
Maya Uzia Beandrade;
Ria Amelia;
Wahyu Nuraini Hasmar
Jurnal Kedokteran dan Kesehatan Vol 18, No 2 (2022): JURNAL KEDOKTERAN DAN KESEHATAN
Publisher : Faculty of Public Health, Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta
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DOI: 10.24853/jkk.18.2.240-248
Kondisi hiperglikemia pada penyakit diabetes mellitus tipe 2 dapat menyebabkan kematian sel baik pada sel β pankreas maupun sel lain. Pencegahan kematian sel tersebut diperlukan untuk mencegah terjadinya komplikasi pada DMT2. Salah satu cara pencegahannya melalui konsumsi zat antioksidan. Kacang kedelai hitam varietas detam II memiliki kandungan senyawa flavonoid tinggi dan berperan dalam antioksidan. Penelitian dilakukan selama 9 bulan dari bulan Februari- Oktober 2020 di Laboratorium Farmakologi dan Sitohistoteknologi STIKes Mitra Keluarga. Metode penelitian yang digunakan yaitu Randomized Controlled Pretest-posttest design. Kelompok sampel terbagi menjadi 5 kelompok yaitu kontrol negatif, positif, perlakukan dengan kadar tablet 500 mg/BB, 750 mg/BB, 1.000mg/BB, pembuatan preparat dengan metode paraffin dan pewarnaan HE. Hasil pewarnaan menunjukkan perbaikan jaringan pankreas yang optimum terdapat pada kelompok tikus yang diberikan tablet kedelai hitam varietas detam II 750 mg/BB. Hasil penelitian ini menunjukkan kedelai hitam varietas detam 2 memiliki kemampuan mencegah kerusakan sel akibat kondisi stress oksidatif.
GAMBARAN KADAR HEMOGLOBIN PADA PEROKOK AKTIF DI TERMINAL KAYURINGIN KOTA BEKASI
Moudy Ramadhanti;
Ria Amelia;
Danny Luhulima
Jurnal Mitra Kesehatan Vol. 2 No. 1 (2019): Jurnal Mitra Kesehatan
Publisher : STIKes Mitra Keluarga
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DOI: 10.47522/jmk.v2i1.30
Pendahuluan: Perilaku merokok berdampak yang buruk terhadap kesehatan. Salah satu zat berbahaya dalam asap rokok yaitu karbon monoksida. Karbon monoksida yang sangat mudah berikatan dengan hemoglobin dibandingkan dengan oksigen maupun karbondioksida. Ikatan karbon monoksida dengan hemoglobin dapat beresiko terjadinya kondisi hipoksia. Jika kondisi ini dibiarkan maka dapat menyebabkan kematian sel. Penelitian ini dilakukan untuk melihat gambaran kadar hemoglobin pada perokok aktif di Terminal Kayuringin Kota Bekasi. Metode: Jenis penelitian yang dilakukan adalah penelitian deskriptif dengan menggunakan desain penelitian cross sectional. Jumlah responden sebanyak 31 perokok aktif yang diperoleh melalui wawancara dan kadar hemoglobin diperiksa dengan menggunakan alat hematology analyzer ABX Micros 60. Hasil: Hasil penelitian kadar hemoglobin pada 31 responden perokok aktif diperoleh nilai rata-rata sebesar 14,5 g/dL, dengan standar deviasi 1,0942 g/dL, nilai tertinggi 16,9 g/dL dan nilai terendah 12,3 g/dL. Kesimpulan: Berdasarkan hasil tersebut dapat disimpulkan bahwa kadar hemoglobin pada 31 responden perokok aktif masih dalam kadar normal. Kadar hemoglobin normal pada perokok aktif diduga sebagai respon tubuh untuk memenuhi oksigen dan menjaga homeostatis agar metabolisme tubuh berjalan normal.
Cross-Reaction Antibody Test between SARS-CoV-2 and Dengue Hemorrhagic Fever in Indonesia
Danny Luhulima;
Tri Soetowo;
Ria Amelia
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 27 No. 2 (2021)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory
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DOI: 10.24293/ijcpml.v27i2.1681
Coronaviruses are a family of viruses that cause illness from the common cold to severe diseases such as Severe Acute Respiratory Syndrome (SARS-CoV). In December 2019, forty new cases of pneumonia of unknown etiology have been reported in Wuhan, China. The disease resembles Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and has been subsequently named the 2019-novel Coronavirus Disease (COVID-19). The antibody test is a blood test that provides quantitative and qualitative detection of IgG and IgM antibodies against the SARS-CoV-2. Reported a male, 43-year oldsuffering from DHF, but the results of an IgG and IgM rapid test were COVID-19 reactive. Also, reviewed rapid tests for COVID-19 and the results showed that only IgG was reactive. This explained that the patient already had SARS Cov-2 antibodies but was not suffering from the disease. The rapid test COVID-19 IgM result was deemed to be a false positive.
Increasing Public Awareness Related To Early Detection Of Diabetes Mellitus In Jatimekar Bekasi Village
Maulin inggraini;
Noor Andryan Ilsan;
Siti Nurfajriah;
Ria Amelia;
Elfira Maya Sari
Jurnal Masyarakat Religius dan Berwawasan Vol 2, No 1 (2023): Masyarakat Religius dan Berwawasan
Publisher : Universitas Islam Negeri Mahmud Yunus Batusangkar
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DOI: 10.31958/mrw.v2i1.8703
Noncommunicable Diseases (NCDs) are a serious threat not only for the elderly but also for the young. Based on a report from the International Diabetes Federation (IDF) by 2022 that 1.57 million of the 8.75 million people living with type 1 diabetes worldwide in 2022 are less than 20 years old. This shows the importance of increasing public awareness about Diabetes Mellitus (DM). This PKM is carried out by providing education about the prevention and dangers of DM, then followed by a Temporary Blood Sugar (TBS) examination in the Jatimekar Bekasi village using brochure media. The increas in participants’s knowledge was carried out by analyzing the pre-test and post-test descriptively. The results of the study showed an increase in public knowledge about DM. this can be seen from the increase in post-test result compared to pre-test scores. GDS examination results include risk characteristics of 86.96% (110-200 mg/dL) and DM 13.04 % (>200 mg/dL). There are 3 counseling participants who suffer from DM and have a history of unhealthy eating patterns and not doing physical activity.
EDUKASI DAN PELATIHAN PEMERIKSAAN INFEKSI SALURAN KEMIH (ISK) PADA SISWA SMK TEKNOLOGI LABORATORIUM MEDIS (TLM) DI KOTA BEKASI
Reza Anindita;
Siti Nurfajriah;
Ria Amelia;
Noor Andryan Ilsan;
Maulin Inggraini;
Elfira Maya Sari
Jurnal Abdi Insani Vol 10 No 4 (2023): Jurnal Abdi Insani
Publisher : Universitas Mataram
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DOI: 10.29303/abdiinsani.v10i4.1180
Urinary Tract Infection (UTI) is an infectious disease caused by bacterial colonization in the urinary tract. The bacteria most commonly found in UTI patients is E. coli. UTI is more common in women (79%) than men (21%) aged 17-35 years. The problem of UTIs causes an increase in morbidity (illness) rates, thereby increasing medical costs. Therefore, early prevention efforts are needed, one of which is through education and the introduction of UTI examinations through Community Service (PKM) activities for secondary school students. The aim of this PKM is to provide simple education and training regarding UTI examination for vocational school students majoring in TLM in Bekasi City. This PKM also provides students with experience in carrying out UTI examinations in the laboratory. This activity was carried out at the family partner STIKES with a total of 43 students majoring in TLM vocational schools. This activity stage includes planning, implementation and evaluation. Data analysis was carried out using descriptive and comparative tests for 2 samples using a paired t-test. The results of this activity showed that there were 37 (86.04%) female participants while there were 6 (13.95%) male participants. The average pre-test score was 3.48 while the post-test was 8.76 or an increase of 15.17%. The results of the paired t-test showed a significant difference between the pre-test and post-test with a significance value of (0.306<0.05). The conclusion of this PKM is that an evaluation using test instruments (pre test and post test) in the form of 10 multiple choice questions was able to significantly increase knowledge about UTI for 43 students of the TLM Department of Health Vocational Schools in Bekasi City.