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Jurnal Health Sains
Published by Syntax Corporation Indonesia
ISSN : 27236927     EISSN : 27234339     DOI : http://doi.org/10.36418
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Jurnal Health Sains adalah jurnal yang diterbitkan sebulan sekali oleh Ridwan Institute. Jurnal Health Sains akan menerbitkan artikel ilmiah dalam lingkup ilmu kesehatan. Artikel yang diterbitkan adalah artikel dari penelitian, studi atau studi ilmiah kritis dan komprehensif tentang isu-isu penting dan terkini atau ulasan buku-buku ilmiah.
Arjuna Subject : Profesi Kesehatan - Bimbingan Kesehatan dan Transkripsi
Articles 764 Documents
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The Relationship Between Occupation and Incidence of Various Types of Melanocytic Nevi Riyanto, Puguh; Alexander, Lim
Jurnal Health Sains Vol. 6 No. 7 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i7.2671

Abstract

Melanocytic nevi (MN) are benign proliferations of melanocytes influenced by genetic and environmental factors, particularly ultraviolet (UV) radiation. Occupational exposure to sunlight may contribute to the development of different nevus types, but this relationship remains underexplored. This study aimed to examine the association between occupation and the incidence of various melanocytic nevi types. A descriptive observational study with a cross-sectional design was conducted among 20 participants in Semarang, Indonesia, from April to May 2025. Data were collected via validated questionnaires covering occupation (indoor/outdoor), protective measures (sunscreen, long-sleeved clothing), and nevus types (junctional, compound, intradermal). Statistical analysis was performed using SPSS. Results showed that 60% of participants had indoor occupations, while 40% worked outdoors. Among nevus types, 50% had compound nevi, 16% had junctional nevi, and 10% had intradermal nevi. A significant association was found between outdoor occupations and compound nevi (p = 0.010, RR = 3.50). No significant links were observed for junctional or intradermal nevi. Protective measures, such as sunscreen use, showed no significant impact, possibly due to low adherence (70% non-users). The findings suggest that occupational UV exposure may elevate the risk of compound nevi. Further research with larger samples and additional variables (e.g., sun exposure duration) is recommended to validate these results and to inform preventive strategies for at-risk populations.
Gingival Enlargement as Initial Manifestation of Acute Myeloid Leukemia : A Case Report Suparthika, Ni Putu Radha Premaiswari
Jurnal Health Sains Vol. 6 No. 7 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i7.2672

Abstract

Acute myeloid leukemia (AML) is a disease of hematopoietic stem cells in the bone marrow that proliferates and differentiates abnormally. AML can develop aggressively and cause a variety of complaints due to bone marrow suppression and symptoms of inflection to individual organs. Symptoms and signs of AML can be caused due to the suppression of the bone marrow resulting in ineffective erythropoesis. The oral cavity can show the first clinical manifestations of leukemia. Individuals with leukemia may show lesions such as enlarged gums. Case Presentation: A 31-year-old female patient was referred from the Dental Polyclinic of Tabanan Hospital with complaints of enlarged gums since 1 month ago. Enlargement occurs in the gums behind which incisors enlarge rapidly. Other complaints include fever up and down, weakness, bleeding through the anus. The results of the Complete Blood test found a very high WBC value, with bicytopenia, with BMP examination showing AML with M4 morphology. Conclusions: In a 31-year-old female patient, gum enlargement was found as an early manifestation of acute myeloid leukemia (AML) accompanied by constitutional symptoms such as fever, weakness, spleenomegaly. Clinical manifestations of AML can include symptoms of suppression of the bone marrow by malignant cells, and infiltration into organ systems. Oral manifestations of AML can include enlargement of the gums, discoloration of the mucous membranes to bluish or pale, ulcers, erosion, bleeding, ecchymosis, which can be mistaken for manifestations of other diseases.
Clinical Features and Management of Community-Acquired Pneumonia (CAP) In The Elderly Arimbi, Muzaijadah Retno; Amori, Lakcandra Amar; Soetedjo, Farida Anggraini; Haryanti, Elizabeth; Yaniari, Roethmia
Jurnal Health Sains Vol. 6 No. 8 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i8.2657

Abstract

Community-Acquired Pneumonia (CAP) or pneumonia acquired outside health facilities is one of the main causes of morbidity and mortality in the elderly age group. As we age, immune function decreases and is accompanied by comorbidities such as diabetes, heart disease, and chronic lung disease that worsen the course of the disease. This study aims to find out the clinical picture and management of Community-Acquired Pneumonia (CAP) in the elderly. This study uses qualitative research methods. The data collection technique in this study is by studying case report documents. The data that has been collected is then analyzed in three stages, namely data reduction, data presentation and drawing conclusions. The results show that Community-Acquired Pneumonia (CAP) in the elderly is a complex condition with challenges in diagnosis and management, as the symptoms are often atypical and involve various risk factors. Clinical guidelines emphasize the importance of basic supporting examinations such as thoracic imaging and organ function evaluations, as well as prompt and appropriate administration of empirical antibiotics. Treatment should be adjusted to the severity of the patient's frailty, comorbidities, and frailty status. Supportive therapy plays an important role in recovery, while an individualized approach based on risk factors such as malnutrition, sarcopenia, and aspiration is needed to improve prognosis and lower mortality in the elderly with CAP.
Clinical Manifestations and Prognosis Factors in Severe Cutaneous Adverse Drug Reaction (Scadr) Oktavriana, Triasari; Lauda, Benedikta; Putri, Osdatilla Esa
Jurnal Health Sains Vol. 6 No. 8 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i8.2674

Abstract

Severe Cutaneous adverse drug reaction (SCADR) is a severe skin reaction due to the use of drugs that can be life-threatening. This article describes the clinical manifestations and prognosis factors that affect SCADR patients. The most common types of SCADR were Stevens-Johnson Syndrome (SSJ) and Toxic Epidermal Necrolysis (TEN). The drugs that most often trigger are antibiotics and anticonvulsants. The main clinical manifestations include erythematosa skin lesions, epidermal necrolysis, and mucosal involvement. Significant prognosis factors include the extent of the affected skin area, internal organ involvement, and SCORTEN score. Patients with high SCORTEN scores have a greater risk of mortality. Early treatment and discontinuation of trigger drugs are key factors in improving clinical outcomes. The conclusion is early recognition of clinical manifestations of SCADR as well as assessment of prognosis factors can be helpful in patient management and reduce the risk of serious complications. The study also highlights the importance of educating medical personnel in detecting and managing severe drug reactions.
The Silent Revolution: A Holistic Strategy To Address Prehypertension In Young And Active Populations Yunus, Moch.; Supriyadi, Supriyadi; Wahjuni, Endang Sri
Jurnal Health Sains Vol. 6 No. 8 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i8.2675

Abstract

Prehypertension is an increasingly prevalent condition among young individuals, particularly those who are physically active. Although not as severe as hypertension, prehypertension can elevate the risk of future cardiovascular diseases. Therefore, it is crucial to implement a holistic approach that integrates exercise, stress management, and dietary changes to manage prehypertension effectively. This study aims to analyze the effectiveness of a holistic approach in addressing prehypertension among young populations through a Systematic Literature Review (SLR). The research methodology follows the PRISMA guidelines by analyzing 32 accredited and relevant international publications. The analysis results indicate that regular physical activity, such as aerobic exercise and High-Intensity Interval Training (HIIT), can significantly reduce blood pressure. Additionally, stress management techniques like meditation, yoga, and progressive relaxation have also proven effective in lowering blood pressure. Dietary modifications, including reduced sodium intake, increased potassium consumption, and adherence to healthy eating patterns, contribute positively to managing prehypertension. In conclusion, a holistic approach that combines exercise, stress management, and healthy eating can serve as an effective strategy for preventing and managing prehypertension in young individuals.
Persistent Hypoglycemia: A Rare Case Report Of Clinically Diagnosed Insulinoma Putri, Hesti Andika; Febryan, Reza
Jurnal Health Sains Vol. 6 No. 8 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i8.2676

Abstract

Insulinoma is a rare disease, with an incidence of approximately 4 cases per 1 million people per year. It is a pancreatic tumor that produces insulin and is classified as one of the functional pancreatic neuroendocrine tumors, originating from the pancreatic ductal cells. In insulinoma, insulin is produced abnormally and continuously, leading to persistent hypoglycemia due to excessive insulin levels. We report a case of a 49-year-old female patient who presented to the emergency department with a chief complaint of generalized weakness. The weakness was persistent and typically occurred before meals, improving after the consumption of sugar water. The patient also reported dizziness, cold sweats, blurred vision, and tremors. Laboratory tests revealed a random blood glucose level of 35 mg/dL, a fasting insulin level of 82.4 µIU/mL, and a C-peptide level of 1.07 ng/mL. Abdominal CT scan did not detect a pancreatic mass, and MRI findings were also inconclusive. Therefore, further evaluation with Endoscopic Ultrasound (EUS) and GLP-1R PET/CT was recommended. The diagnosis of insulinoma was made based on clinical and biochemical findings, fulfilling Whipple’s triad and the diagnostic criteria of blood glucose < 55 mg/dL, insulin ≥ 55 µIU/mL, and C-peptide ≥ 0.6 ng/mL. The therapeutic algorithm for clinically and biochemically confirmed insulinoma includes: stabilization of hypoglycemia, evaluation of tumor resectability, and administration of medical therapies such as everolimus, peptide receptor radionuclide therapy (PRRT) with Lu-177, chemotherapy, and local ablation techniques in cases of refractory disease.
Scoping Review: Factors Causing Claim Pending in Indonesian Hospitals Zalukhu, Linna Asni; Permanasari, Vetty Yulianty
Jurnal Health Sains Vol. 6 No. 9 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i9.2679

Abstract

Pending claims are one of the crucial problems often faced by hospitals in the National Health Insurance (JKN) financing system. This condition not only causes disruptions to hospital cash flow but also reflects weaknesses in the claims management system administratively, technically, and systemically. This study aims to identify and map various factors causing pending BPJS Kesehatan claims in Indonesian hospitals through a scoping review approach. The review process was carried out with reference to the Arksey and O'Malley framework and the PRISMA-ScR guidelines, using literature sources from Google Scholar, Garuda, PubMed, and Neliti databases. Article selection was conducted systematically for publications from 2022–2024, in Indonesian, available in full-text form, and indexed at least SINTA 3. Of the 268 articles identified, 10 met the inclusion criteria and were further analyzed. The results of the synthesis show that the causative factors of pending claims can be grouped into five main themes: inaccuracy in coding diagnosis and procedures, incompleteness of claim documents, limitations of information systems, low competence of human resources, as well as inconsistencies in the implementation of SOPs and weak coordination between units. This study concludes that pending claims are multifactorial and interrelated, requiring comprehensive intervention in the form of strengthening human resource capacity, optimizing the digital claims system, and improving hospital claims policies and governance systemically.
The Influence of Defecation Behavior, Drinking Water Sources, and Handwashing Habits N Stunting in the Work Area of Merek Community Health Center Perangin-angin, Susanti Br; Sembiring, Haesti; Manik, Erba Kalto
Jurnal Health Sains Vol. 6 No. 9 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i9.2681

Abstract

This research was conducted due to the low motivation of the community in the work area of the Brand Health Center to build CTPS facilities, healthy latrines, and clean water management systems. The limited ownership of these facilities is a major factor contributing to the failure to achieve key indicators of STBM, such as the high prevalence of open defecation. This study employed an action research design with an observational approach and educational interventions. The process began with problem identification through observation and surveys, followed by community education and assistance in constructing CTPS facilities, managing clean water, and building latrines. Before the intervention, residents in several villages within the Brand Health Center area were less motivated to develop CTPS facilities, clean water systems, and latrines, due to low knowledge, financial constraints, and limited awareness of the importance of a clean and healthy lifestyle. After direct education and mentoring, there was an increase in motivation and independent efforts by the community to establish these facilities. The results showed improvements such as a reduction in open defecation, the adoption of handwashing with soap, and better practices in managing drinking water. To ensure sustainability, it is recommended that regular supervision and continued assistance be provided so that these achievements remain consistent in the long term.
Comparison of the of Operative Treatment and Sclerotherapy Injection in the Management of Hemorrhoids: A Meta-Analysis of Randomized Controlled Trials Wiyardhani, Laras; Sander, Tara; Wibriansyah, Akbar
Jurnal Health Sains Vol. 6 No. 9 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i9.2695

Abstract

Rubber-band ligation (RBL) and sclerotherapy are the two most widely used office-based interventions for symptomatic haemorrhoidal disease, yet their comparative benefits remain uncertain. This systematic review and meta-analysis evaluated the relative efficacy and safety of sclerotherapy versus operative treatments (primarily RBL and excisional procedures). The primary objective of this systematic review and meta-analysis was to evaluate the relative efficacy and safety of sclerotherapy versus operative treatments (primarily RBL and excisional procedures) in the management of hemorrhoidal disease. Treatment success was 78.2% in operative arms (701/896) versus 74.1% with sclerotherapy (665/897); pooled RR = 1.03 (95% CI 0.91–1.17; I² = 85%), indicating non-inferiority of sclerotherapy. Recurrence in two trials (n = 302) showed lower recurrence after sclerotherapy (12.9%) than after operative treatment (28.4%); RR = 2.22 (95% CI 1.37–3.58; I² = 0%). Pain in three trials (n = 335) reported a higher risk of significant pain following operative procedures (RR = 1.17, 95% CI 1.02–1.34; I² = 60%) and greater mean pain intensity (SMD = 0.96, 95% CI 0.22–1.71; I² = 89%). Sclerotherapy achieves comparable short-term symptom control to operative treatments while offering superior durability and a more favorable pain profile. Given its minimal invasiveness and ease of repetition, modern sclerotherapy should be considered a first-line option for grade I–III haemorrhoids. High between-study heterogeneity underscores the need for standardized protocols and longer follow-up.
The Effectiveness of Android-Based Simantb (TB Monitoring Information System) on Medication Compliance of Pulmonary TB Patients in Ende Regency, East Nusa Tenggara Susanti, Maria; Arwani, Arwani; Widiyanto, Budi
Jurnal Health Sains Vol. 6 No. 9 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i9.2696

Abstract

Tuberculosis (TB) is an infectious disease and one of the leading causes of death worldwide. One indicator of the TB control program's success is the treatment success rate. Various factors are believed to hinder the success of TB treatment, including therapy failure due to non-adherence, which is one of the main factors. Therefore, appropriate interventions are needed to monitor and evaluate TB patient medication adherence using suitable media that are easy to use and accessible anytime and anywhere through mobile health technology. This study aimed to analyze the effectiveness of the Android-based SIMANTB application on medication adherence in pulmonary TB patients. The research employed a Research and Development (R&D) design with a pre-experimental approach using a static group comparison, conducted over 28 days (1 month). The sampling technique used was simple random sampling, consisting of 30 respondents divided into intervention and control groups. Research data were analyzed using the Shapiro-Wilk and Mann-Whitney tests. The SIMANTB application was found to be highly suitable for tuberculosis patients, with material feasibility percentages of 93.06% and 93.75%. The use of the Android-based SIMANTB application significantly increased medication adherence in TB patients (p = 0.004). The development of the Android-based SIMANTB application is expected to provide a solution for health workers (doctors, nurses, TB officers) to support TB patients in monitoring and motivating their treatment, thereby increasing the success rate of treatment.

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