cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Masriadi
Contact Email
arimasriadi@gmail.com
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Unknown,
Unknown
INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 371   372   373   374   375 
Diagnostic Value of Mid Regional Proadrenomedullin as a Sepsis Biomarker in Pediatric Patients with Cancer-Related Chemotherapy Joko Susanto; Muhammad Robiul Fuadi; Mia Ratwita Andarsini
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17569

Abstract

The aim of this study was to analyze the diagnostic value of mid regional proadrenomedullin as a sepsisbiomarker in pediatric patients with cancer-related chemotherapy. This cross-sectional observationalstudy was located in General Hospital Dr. Soetomo Surabaya from September until December 2020.International Pediatric Sepsis Consensus Conference criteria was used to define sepsis term on 2 studygroups. Serum mid regional proadrenomedullin has been drawn from 60 subjects (41 in-ward pediatricpatients) and measured on sandwich enzyme-linked immunosorbent assay from Elabscience® HumanMid Regional Proadrenomedullin. Humareader Single Plus® was used to measure the optical density.ROC analysis was used to find out cut off value, sensitivity, specificity, positive predictive value, negativepredictive value, negative likelihood ratio, positive likelihood ratio, and accuracy, respectively. Statisticsdeclared significant if p<0.05 (95% CI). Between groups, temperature and heart rate were statisticallydifferent (p<0.001; 95% CI). The median difference of mid regional proadrenomedullin between groupswas significant (p<0.05; 95% CI). Cut off value 2,88 nmol/L, sensitivity 60.0%, specificity 56.67%,positive predictive value 58.06%, negative predictive value 58.62%, positive likelihood ratio 1.38,negative likelihood ratio 0.71 and diagnostic accuracy 59.33% was obtained while area under curvewas 0.707, respectively. Sepsis in children with cancer –related chemotherapy has not well diagnosedby serum mid regional proadrenomedullin.
The Effect of Adiponectin Recombinant in Rattus Norvegicus with Polycystic Ovarium Syndrome Model on Anti-Müellerian Hormone Expression Joseph Chandra Relmasira; Jimmy Yanur Annas; Widjiati
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17570

Abstract

Background: Polycystic Ovary Syndrome (PCOS) is an important disease that causes various healthproblems in women. Ovulation - infertility disorders are found in 60-85% woman with PCOS. Anti-Muellerian Hormone (AMH), a protein from Transforming Growth-b Family, often increased in patientwith PCOS and associated with severity and poor prognosis for assisted reproductive outcome. Dietaryand lifestyle changes are the first-line therapies but consistent application of this method is difficult toattain for people with PCOS. Adiponectin, a product by adipose cells have a significant reduction inobese and women with PCOS. The purpose of this study was to see the differences in AMH expressionbetween mice with polycystic ovary model treated with adiponectin recombinant and mice withpolycystic ovary model treated with placebo and control.Method: This research is an experimental study with a Post Test Only Control Group design. Thesample of this study was 3 months female Rattus norvegicus Wistar strain weighing 110-120 g. Thesample size was 36, which were divided into three groups, K0 (control group of mice with polycysticovary model), K1 (group of mice with polycystic ovary model that received placebo injection), and K2(group of mice with polycystic ovary model that received 5 μg/ml injection of recombinant adiponectin).Polycystic ovary model made by injecting 10 mg/Kg body weight testosterone propionate for 14 days.The injection is carried out at the proestrous stage. The three groups of mice in a period of 3 weeks aftertreatment, were surgically removed according to the sampling procedure, then the ovaries were given acode and immunohistochemical staining was performed to see the AMH expression in the ovaries. Thedata were collected, then statistical analysis was carried out using SPSS software.
Demographic Profile of Deaths Due to Drowning in and Around Vijayawada, Andhra Pradesh K. Ravimuni; K. Usha Rani
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17571

Abstract

Drowning is a leading and preventable cause of death that has suffered an attention deficit. The WorldHealth Organization identifies data collection as a key strategy underpinning effective interventions.The circumstances leading to drowning are complex. People interact with water primarily for recreationand often interact with water due to daily life or occupational endeavours. A Significant reductionthe number of drowning deaths among young children in private swimming pools has been achievedthrough over 30 years of focused work on the epidemiology and risk factors for drowning in privateswimming pools among young children. Proposed contributory factors for drowning in rivers includea lack of barriers controlling access to water, an absence of adult supervision for young children, poorswimming skills, minimal awareness of the dangers, the consumption of alcohol, transportation onwater, a lack of safe water supply, and disasters related to flooding.
The Role of K and Ca Channels in Hydrogen Sulfide Induced Relaxation in Arteries Feeding Human Colorectal Cancer Kamaran. H. Mohammed; Omar A. M. Al-Habib; Sardar H. Arif
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17572

Abstract

This study was designed to find out the vasorelaxant effects of hydrogen sulfide (H2S) on arteries feedinghuman colon cancer. In addition, it also included the study of the possible roles of potassium (K+) andcalcium (Ca2+) channel types in H2S-induced relaxation in the isolated arteries. Sodium sulfide (Na2S)showed a potent dose-dependent relaxant effect on Norepinephrine (1X10-5 M) precontracted arteries.The use of different specific K+ channel blockers (BaCl2, 4-AP, GLIB, and TEA) individually indicatedH2S-induced relaxation was affected by all K channel types participated to a various extent, except Kvchannels. Both Kca2+ and Kir channels played a major role in the induced relaxation, while KATP playeda minor and non-significant role. On the other hand, Kv channel played no direct role, and the inducedresponse curve was very close to that of the control. Possible combinations of K channel blockersshowed that some produced synergistic effect to different extent, whereas others produced mild andnon-significant effect except at the highest doses used on dose-response curves. Thus, combinations of(GLIB+4-AP), (GLIB+BaCl2) and (BaCl2+TEA) caused a highly significant blocking in the inducedresponse curve, while (BaCl2 +4-AP) and (TEA+4-AP) produced a mild inhibition except at the highestdoses used in which the inhibition was significant.
The Influence of Safety Management Practices on Safety Performance in Nurses of Emergency Installation on The Government Hospital of Surabaya Khaulah Syahidah; Noeroel Widajati; Nurhayati Saridewi
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17573

Abstract

Introduction: Hospital is one of the high-risk workplaces in terms of safety and health. Nurses arethe most vulnerable health workers to work accidents because they have the most number in a hospitaland most often interact with patients. Safety performance is very important for the prevention of workaccidents. This research aimed to analyze the influence of safety management practices on safetyperformance in nurses of the emergency installation at X Hospital of Surabaya.Methods: This research was an observational research with the cross-sectional design. It was conductedin May to June 2019. The population in this study was 208 nurses and the sample obtained using asimple random sampling technique involving 68 nurses. In assessing safety management practices andsafety performance, the researcher used questionnaires, observation, and interviews.Results: The results presented that safety training which was a dimension of safety managementpractices affected on the safety performance with a p-value 0.000. Suggestions in this research, toimprove safety performance, management can conduct specific and periodic safety training, holdingsafety briefing and safety talk on a regular basis, and implementing a safety award by applying a systemof reward and punishment.Conclusion: Hospital management still needs to schedule a specific and periodic safety training fornurses. Furthermore, to improve safety performance, management can holding safety briefing andsafety talk on a regular
Immediate Postoperative Radiographic Assessment of Hip Arthroplasty Khitam Hamid Kamil; Safwan Saeed Mohammad; Mohammad Saeed Mohammad
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17574

Abstract

Radiograph is the keystone in the assessment of hip arthroplasty, as it is available with no metalartifact , at a low cost, and facilitating longitudinal comparison. Pelvic radiograph is significant toassess post-operative hip arthroplasty. So we aim to assess the outcome of the operation throughimmediate radiography for hip arthroplasty and to determine the different types of hip arthroplasty.This prospective study were conducted at surgical specialized hospital and nursing home hospital /medical city complex / Iraq-Baghdad at radiological departments by seimens x.ray machines , in theperiod between ( October 2020 – march 2021) . Fifty patients were included . The results showedafter radiographic evaluation of hip arthroplasty , 90.0% of cases was Equal Leg length. The higherpercentage of vertical center was (90.0 %) for similar compared to lower percentage was(10.0%) nonsimilar , (96.0%) of horizontal center was similar compared (4.0%) non similar .The higher percentageof acetabular inclination was (78.0%) for angle 45degree compared to lower percentage was(6.0%) forangle 50 degree , the higher percentage of acetabular anterversion was (30.0%) for angle 25 degreecompared to lower percentage was(2.0%) for angle 30 degree. The percentage for femoral stem positionwas (100.0%) for neutral alignment . (90.0%) not used of cement mantle compared to (10.0%) usedcement mantle , the thickness in range 2-3mm . (94.0%) was no any early complications compared to(6.0%) was Superficial infection.
The Effects of Chemicals Used For Suicide on Insect Succession, Diversity and Development: An Animal Model Kianoush Ghiasvand; Niloofar Soltanian; Maryam Naghshzan; Simin Pouladian; Amin Hoseinpour; Aboozar Soltani
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17576

Abstract

It has proven that the presence of different chemicals can affect the succession patterns of necrophagousinsects. A comprehensive study was designed on the effects of nortriptyline, diazinon, and aluminumphosphate on arthropod’s succession and diversity on cadavers.Sixteen rabbits in two groups were used as a model in this study, 12 of them were treated with the drugsand were placed in two habitats (sun and shade) based on the study design. For each group, one cagewas considered as control. Insects were collected twice a day from the cadavers and identified.In total, 549 necrophagous insects from five families, were collected from all the carcasses. Chrysomyaalbiceps was the dominant insect on all cadavers, expect for one treated with diazinon, in which it wasdisplaced by Dermestes frischii. The highest number of insects were collected on the sixth day for allcadavers. The majority were collected from the shaded cages.Generally, the species diversity was higher for all the cadavers treated with the drugs compared to thecontrol cadavers. The results showed that the presence of diazinon in the cadaver can repel necrophagousinsects, on the contrary nortriptyline seems to attract more species/specimen.
Hippocampal Volume and Entorhinal Cortex Thickness in Alzheimer’s Disease Leon Agung Manurung; Widiana Ferriastuti; Bambang Soeprijanto; Hartono Yudi Sarastika
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17577

Abstract

Magnetic Resonance Imaging (MRI) is the standard imaging evaluations in Alzheimer’s Disease (AD).Information regarding hippocampus and entorhinal cortex sizes plays an important role in Alzheimer’sdisease. This study aims to determine hippocampal volume and entorhinal cortex thickness inAlzheimer’s disease obtained from a group of patients who underwent head MRI.This study was an observational study with retrospective approach in patients who were diagnosedwith AD and had available head MRI examination results. A total of 14 patients were diagnosed by aneurologist with AD using MMSE, Hachinsky, and NIA-AA criteria.From head MRI measurement in AD patients, we found that the mean volume of right, left, andtotal hippocampal was 1700±0.395 cm3; 1.670±0.349 cm3; and 3.370±0.725 cm3, respectively. Themean thickness of right, left, and total entorhinal cortex was 1.821±0.459 mm; 1.463±0.369 mm; and3.285±0.791 mm, respectively. There is a possible difference between the early and late stages of AD inthe same patient. Further studies with larger cohorts are needed to examine these correlations.
The Higher Level of Neutrophil – Lymphocyte Ratio (NLR) and Serum Syndecan-1 Based on Timeline (First, Sixth, and Twenty-Fourth Hour) in Sepsis-Induced Acute Kidney Injury Lila Tri Harjana; Eddy Rahardjo; Windhu Purnomo; Lilik Herawati; Nancy Margarita Rehatta
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17578

Abstract

This study aims to analyze the difference between the NLR and serum syndecan-1 level at the first,sixth, and twenty-fourth hours with the incidence of acute kidney injury (AKI) and non-AKI in sepsis.We observed thirty-one adult sepsis patients who admitted to the emergency room and ICU of Dr.Soetomo General Academic Hospital, Surabaya, Indonesia from March 30, 2020, to July 5, 2020 (fourmonth),and differentiated into two groups, AKI group (n=14) and non-AKI group (n=17). All septicpatients have been given the standard treatment based on Survival Sepsis Campaign 2018. The resultsshowed that the NLR at 1st-hours, 6th-hours, and 24th-hours in the non-AKI group were lower thanthose in the AKI group (1st: 15.9±2.6 vs 33.0±11.3; 6th: 14.2±1.8 vs 19.3±3.8; and 24th: 11.6±1.3 vs19.9±3.8) (p <0.00). Almost NLR at every groups based on serial hours were decreasing, except in theAKI group, the NLR at the 24th-hour group was higher than the NLR at 6-hour group, but still lowerthan the NLR at 1st-hours. Serum syndecan-1 levels were lower in the non-AKI group than in theAKI group, at 1st, 6th, and 24th-hours, (1st: 532.5±72.0 ng/mL vs 597.2±85.8 ng/mL; 6th: 557.6±71.6ng/mL vs 612.0±73.9 ng/mL; and 24th: 548.4±76.6 ng/mL vs 586.4±84.6 ng/mL) (p <0.05). It canbe concluded that the neutrophil-lymphocyte ratio (NLR) and serum syndecan-1 levels at 1st, 6th,and 24th hours is higher in the AKI compared to non-AKI groups in sepsis. Hence, NLR and serumsyndecan-1 have a potential biomarkers for sepsis-induced AKI.
The Potential of A Balinese Traditional Medicine Kelor Leaves (Moringa oleifera) For Male Infertility Treatment : A Mini Review Luh Putu Widiastini; I. G. Agung Manik Karuniadi; I Nyoman Mangku Karmaya; I Gede Widhiantara
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17579

Abstract

Infertility is one of the causes of reproductive welfare disorders of married couples around the world.One of the causes of infertility at the molecular level is Oxidative Stress (OS) because the products ofReactive Oxygen Species (ROS), both endogenous and exogenous, exceed the levels of antioxidants inthe body. The aims of this review is to find out the potential of traditional medicinal from Bali, Indonesiawith local name Kelor (Moringa oleifera) leaves in preventing the occurrence of potential infertilityin men based on the results of research in vivo using animal trials. The method used by the writer is aliterature study.The results of this literature review found that kelor/moringa had a positive effect onsexual behavior, especially an increase in libido. In addition, it has a positive effect on spermatogenesis,the quality of spermatozoa especially increases sperm motility, sperm count/volume, germ cell count,renews endogenous antioxidant enzyme activity, reduces levels of ROS, and provides a protectiveeffect on the testes from damage. Moringa oleifera contains many free radical blocking molecules.Some phytochemical test results show that moringa contains powerful antioxidants, including alkaloids,flavonoids, saponins, triterpenoids/steroids, tannins.

Page 373 of 550 | Total Record : 5497

 371   372   373   374   375 

Filter by Year

2020 2022


Reset
Filter By Issues
All Issue Vol. 16 No. 3 (2022): Indian Journal of Forensic Medicine and Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology More Issue