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Indian Journal of Forensic Medicine & Toxicology
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Articles 5,497 Documents
A Study of Acute Renal Failure in the Users of Proton Pump Inhibitors Amir M. Shumran; Fakhir M Alzubaidy; Faidh Y. Ahmed
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14803

Abstract

Background: Proton pump inhibitors are one of the most common classes of medications that act by inhibitinggastric H+/K+ adenosine triphosphatase via covalent binding to the cysteine residues of the proton pump,they provide the most potent acid suppression available. Lansoprazole, pantoprazole, and dexlansoprazolehave the greatest bioavailability and achieve the highest plasma levels. Rabeprazole is the most acid-labilePPI and therefore the most potent, whereas pantoprazole is the least reactive and therefore the least potentPatients and methods: Research data were collected from Al-zahraa teaching hospital/ Wasit province andMorgan teaching hospital/ Babylon province, they include patients with acute renal failure who used/ usingproton pump inhibitors compared with those do not use proton pump inhibitors to know the probable relationbetween acute renal failure and the use of proton pump inhibitors. Results and discussion: Results showedthat only 30 patients of 120 patients with acute renal failure consult the hospital were PPIs users, this mayrefer to presence of a relationship between proton pump inhibitor and acute Renal failure . Previous studiesin this field referred to a similar relationship, a case reports and a recent case series implicating these drugsin acute interstitial nephritis (AIN) and progression to acute renal failure.
Evidentiary Value of Forensic Report in Criminal Liability in Jordanian Law Moayad Hosni Ahmed Al-Khawaldah; Abdullah Ahmed Al-Khasilat
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14804

Abstract

Forensic medicine is an important part of criminal justice, which the judiciary resort to, with the purposeof deciding on a number of cases. One of the most important of these cases, in which forensic medicine isthe basis for determining criminal responsibility or not, is the case of allegation or suspicion of death bymurder or unknown reasons that lead to suspicion of murder. This research will address the evidentiary valueof the forensic physician’s report, as it is a means of proof or a means of assessing evidence or an auxiliaryprocedure for the judge. It will also address the authority of the criminal judge in assessing the forensic reportand the position of the Jordanian Court of Cassation on that. A number of findings and recommendationsemerged, the most important of which is that the Jordanian legislator has set up the reports and medicalcommittees system No. 13 of 2014 and its amendments. This system deals with many medical committees,including the forensic committee. The Jordan legislator has also defined the system of expertise beforeregular courts for 2018 and its amendments, according to Article 11 / c which states that a forensic physicianshall be appointed either from forensic physicians appointed in the Ministry of Health, the Royal MedicalServices, official university hospitals, or from those retired among them. I wish the Jordanian legislatorwill set up a legal system for forensic physicians, which shall be independent of the medical reports andcommittees system No. 13 of 2014 and its amendments and the expertise system before regular courts of2018 and its amendments. The proposed system is the Judicial Committee system for forensic physicians,and the reason for this is because the experience of forensic physicians is often the source of the basis for thejudge’s ruling, especially in cases of murder for unknown and suspicious reasons.
Immunoinformatics Analysis of SARS-CoV-2 Isolated from Karst of Bats in Malang, Indonesia Moch Irfan Hadi; Aditya Sukma Prawira; Khuliyah Candraning Diyanah; Dedy Suprayogi; Soedjajadi Keman; Yudied Agung Mirasa; M Yusuf Alamudi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14805

Abstract

In December 2019, cases of mysterious pneumonia were first reported in Wuhan, Initially, the diseasewas temporarily named as 2019 novel coronavirus (2019-nCoV), then WHO announced a new name onFebruary 11, 2020, namely Coronavirus Disease (COVID-19) which is caused by a virus Severe AcuteRespiratory Syndrome Coronavirus-2 (SARS-CoV-2). This virus can be transmitted from person toperson and has spread widely in China and more than 190 other countries and territories. Meanwhile inIndonesia, up to September 2020, 203 thousand cases of COVID-19 were found and 8336 deaths. Batsact as important disease reservoirs for various etiologic agents of disease that can be transmitted betweenspecies, infecting humans and mammals, both domestic and wild. The purpose of this study was to analyzeSARS-CoV-2 immunoinformatics in bats in Karst Malang Indonesia as the basis for making SARS-CoV-2vaccines. This research method is SARS-CoV-2 amino acid bats in Karst Malang, Indonesia analyzed byimmunoinformatics. From the research results, it was found that SARS-CoV-2 protein from Malang Karstbats were antigen, non-allergen and non-toxin, so that they could be used as vaccine candidates, diagnostickits and immunotherapy.
Does Virtual Brain Autopsy Could be Used as a Clue for Detection of Personal Identity? Mohamed A M; Ghada M E; Sherin S G; Makloph MG
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14806

Abstract

Background: virtual autopsy nowdays show great success in human identification. Nowdays singleComputerized tomography of the brain could help answering many questions regarding the identity ofhumans, it could lead us to the gender ,weight and height roughly of the person in question.Patients and Methods: cross- sectional study during the period April 2019 till Mars2020 , One hundredand fifty participant aged between 15 and 29 years old were envolved in the current study after taking theirwritten and verbal consent or their caregiver and doing C T Brain for every one of the studied participant.Results: brain volume is statistically significant with weight , height, gender of the studied participant hencewe could use CT Brain to know the brain volume and then we could suspect weight , height and even genderso we can reach to the identity of the individual.Conclusion: We me be no longer in need of doing autopsy where virtual autopsy could find the answer tomany questions in research, where a correlation was found between brain volume ,gender, weight and height.
Genotyping of Human Papilloma Virus Causing Skin Wart among Iraqi Patients Mohammed Ghani Madlu; Wissam Saleh Abood
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14807

Abstract

The papillomaviruses are a large group of tiny, non-enveloped DNA viruses that in several differentanatomical locations can cause squamous epithelial tumor’s (warts and papilloma’s). There is a closeassociation between HPV and cervical uterine cancer . The genome is composed of 7200–8000 base pairsand is divided into three parts, early region (E) comprising of E1, E2, E4–E8 and reflecting 50 percent of theL1 and L2 genome, Genomic DNA from wart tissue samples were extracted by using gSYAN DNA mini kitextraction kit . The Real Time PCR primers for detection and genotyping of DNA Human papillomavirustype 1 and type3 and type6 based on L1 gene that designed in this study using NCBI-Genbank Sequencedatabase and primer 3 plus . The genetic study included analysis of a common DNA to HPV that was foundin 20 % of cases and DNA fragment specific to HPV type 1, 3 and 6 based on real time PCR. Type 1 HPVwas not approved to present in any sample in the study. Type 3 HPV was identified in a single case. HPV 6was identified in 8 cases, Therefore, type 6 HPV is the most common genotype, followed by type 3.
Microbial Infections Associated with Diabetic Foot Ulcer in Nasiriyah City Muna F. Jahad; Mohammed Hashim AL-Yasiri
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14808

Abstract

Diabetic foot ulcers (DFUs) are a major complication of diabetes lead to development of gangrene associatedwith reduced patient quality of life, lower-extremity amputation, hospitalization, and high morbidity andmortality. This study was aimed to identify the pathogenic microorganisms in diabetic foot ulcers and to testtheir antibiotic susceptibility. A total of 134 patients with diabetic foot ulcers (DFU) attending to Diabeticcenter/ Thi-Qar province, South of Iraq were randomly selected. Samples were cultured for isolating bacteriaspecies and Fungi species. Antibiotic sensitivity testing for bacteria species was done by Kirby Bauer discdiffusion method. Elderly diabetic males were frequently observed to develop foot ulcers higher than female.The most of patients 56 (41.79%) were in the age group 51 to 60 years followed by the 36 (26.86%) patientswere in age group 41 to 50 years. Out of 162 isolates, bacteria species was 116 (71.6%) more than Fungispecies 46 (28.4%). The most isolated bacteria was Proteus mirabilis 25 (15.43%) followed by Enterobactercloacae 22 (13.58%) and both Escherichia coli and Staphylococcus epidermidis 17 (10.49%). Diabetic footinfections are life-threatening. Many pathogens associated with diabetic foot ulcers.
Genotyping of Human Adenovirus Causing Conjunctivitis and Correlation to Age and Gender in Al-Diwaniyah Province in Iraq Muntadher A. Hawass; Wisam S. Alrubaye; Haider Aswad Layikh
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14810

Abstract

Human conjunctival swab samples from 108 patients were male 58 (53.7 %) and female 50 (46.3 %) witha male to female ratio of 1.16:1.for the period from October 2019 to February 2020. Patients were selectedaccording to clinical diagnosis by a specialist ophthalmologist. Diagnosis was confirmed by real time PCRthat showed 84 patients (77.8%) with positive result; %).The study groups were divided into groups withdifferent age and gender. Those aged 15–40 years had much likely to be infected than those aged 55 years.Positive rate in mild cases was 8 (26.7 %), in moderate cases was 40(95.2 %) and in severe cases was 36(100.0 %). Phylogenetic tree analysis of local conjunctivitis based on the Hexon gene partial sequence ofhuman adenovirus show genetic relation to human adenovirus 8 and 56 hexon gene .
Study How People Are Ready To Be Infected with the Corona Virus (COVID-19) in Najaf Province/Iraq Nadia Habeeb Sarhan; Zainab Abdullah Waheed
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14812

Abstract

The current study was designed to investigate some variables that affect the individual’s readiness to contractcoronavirus (COVID-19) for a specific sample in the Najaf governorate. About 70 cases have participatedin the questionnaire that was put on social media for the period from (1 March 2020) to (1 May 2020) ofthe population of the Najafi community – Iraq. The ages ranged between (16-70) years. The overall resultsobtained in this study showed that a group of variables showed a high willingness in the individual tocontract Coronavirus, such as not taking vitamins, zinc, and complementary minerals and less exposure tothe sun to support the immune system at a rate of (58.57%), The use of surgical masks instead of masks N95and the use of Dettol at a high rate when studying the study to get rid of the virus and eliminate it by ratios(88.57%, 47.14%) respectively At a probability level (P < 0.05 ). In addition, there was a lack of awarenessof preventive methods, such as continuing to wash hands with soap and water in the proportion (8.57%)of the total sample. Use of tissue during sneezing in the public, with average proportions (37.14%) withthe participation of samples from most of the Residential neighborhoods in Najaf. The results also showedthe variance of the mean value according to each axis which were, first axis (health activities), second axis(Commitment to prevention methods) and third axis (Commitment to instructions in light of the conditionsof society and instructions) with values of 2.12, 2.75 and 2.22, respectively, beside the relationship andconnection among them.
Detection of Mycotoxigenic Fungi on Food from Markets with the Polymerase Chain Reaction Method for Halal and Thoyiban Food Mohammad Sukmanadi; Retno Sri Wahjuni; Kadek Rachmawati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14813

Abstract

Secondary metabolites of filamentous mold are mycotoxins, which in some situations can develop on foodsderived from plants or from animals. Fusarium, Aspergillus, and Penicillium are the most common types ofmold that produce mycotoxins and also often contaminate human food and animal feed. Aflatoxins includingaflatoxin B1, B2, G1 and G2 are produced by A. flavus and A. parasiticus. M1 and M2 aflatoxins arefound in dairy products. In this study, we used PCR to detect and identify mycotoxigenic fungi material infoods from traditional markets and supermarkets in Surabaya, Indonesia. Samples of chicken meat from atraditional market and from a supermarket (10 pieces each) were placed in a conical tube and crushed in PBS.The crushed samples were centrifuged and the supernatants were cultured on potato dextrose agar (PDA)media and observed using a reverse microscope. DNA was isolated from cultured samples and subjectedto PCR with primers specific for genes encoding aflatoxins. Interestingly, we revealed that the PolymeraseChain Reaction (PCR) analysis showed A. flavus and A. ochraceus were present on chicken meat sold attraditional markets and supermarkets. In sum, enhanced precautions may be needed to ensure that foods soldin traditional markets and supermarkets are free from molds that have the potential to produce mycotoxins.Further studies are needed to detect and identify the prevalence of mycotoxins in the food supply.
Differential Diagnosis for Pericoronal Radiolucencies affecting Jaws – A Case Report on Dentigerous Cyst Mohana Bhoraskar; Ceena Denny E; R. Arvind; Ravikiran Ongole; Almas Binnal; Nidhi Manaktala
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14814

Abstract

Most of the times it is difficult for the clinicians to confirm the clinical diagnosis without investigationsas the clinical picture of oral lesions may be similar to many other conditions. Hence, appropriate clinicalexamination, coupled with radiological and histopathological investigations could aid in appropriatediagnosis and management of the lesions. This article elaborates on differential diagnosis for pericoronalradiolucencies affecting the jaws in a patient presented for a routine dental examination. Differentialdiagnosis helps us to diagnose a specific lesion by eliminating those lesions which appear clinically similar.As advanced diagnostic aids are available, decision-making has become much easier for these lesions.