cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
dwi rizki febrianti
Contact Email
dwirizkyfeby@gmail.com
Phone
+6285222400404
Journal Mail Official
jifi@stikes-isfi.ac.id
Editorial Address
Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin Jl. Flamboyan III/7C Kayu Tangi 70123 Banjarmasin Kalimantan Selatan Telepon: (0511)-3301610, 3300221 Email: jifi@stikes-isfi.ac.id
Location
Kota banjarmasin,
Kalimantan selatan
INDONESIA
Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 358 Documents
 32   33   34   35   36 
PROFIL FINGERPRINTING KLT DAN PENENTUAN AKTIVITAS PENANGKAL RADIKAL BEBAS (DPPH) FRAKSI METANOL, ETIL ASETAT, DAN N-HEKSAN DAUN DADANGKAK (Hydrolea spinosa L.) Dwi Rizki Febrianti; Desy Ayu Lestari PRAMUDITO; Rakhmadhan Niah PRAMUDITO; Eka Kumalasari; Inderiyani; Novia Ariani; Subagus Wahyuono; Siska Musiam
Jurnal Insan Farmasi Indonesia Vol 9 No 1 (2026): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/4r6vja90

Abstract

Dadangkak leaves (Hydrolea spinosa L.) contain various secondary metabolites with potential antioxidant activity. This study aimed to evaluate the thin-layer chromatography (TLC) fingerprinting profile and antioxidant activity of the n-hexane, ethyl acetate, and methanol fractions of Dadangkak leaf extract. Extraction was performed using ethanol followed by fractionation based on solvent polarity. Compound profiling was analyzed by TLC under UV light at 254 and 366 nm using several spray reagents. Antioxidant activity was assessed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method with UV-Vis spectrophotometric measurement at 517 nm to determine IC₅₀ values. The results demonstrated that the methanol fraction exhibited the most comprehensive chromatographic profile, showing positive responses to all spray reagents, indicating a higher diversity of secondary metabolites compared with the other fractions. All fractions showed free radical scavenging activity against DPPH radicals. The IC₅₀ values were 0.110 ppm for the n-hexane fraction, 0.245 ppm for the ethyl acetate fraction, and −1.588 ppm for the methanol fraction. Furthermore, the methanol fraction showed the highest coefficient of determination (R²), indicating the strongest linear relationship between concentration and inhibition percentage. These findings suggest that the methanol fraction possesses the greatest potential as a natural antioxidant source.
EKSPLORASI POTENSI ANTIBAKTERI DAUN PIDADA MERAH (SONNERATIA CASEOLARIS) TERHADAP BAKTERI PENYEBAB JERAWAT PROPIONIBACTERIUM ACNES Eka Kumalasari; Rizki Arianto; Dwi Rizki Febrianti; Novia Ariani; Muhammad Ma'ruf
Jurnal Insan Farmasi Indonesia Vol 9 No 1 (2026): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/v1f3zg64

Abstract

Acne that appears on the face can cause changes in the form of swelling, redness, pus and cause pain so that it will cause an impression that is less attractive in appearance and affects beauty. One of the causes of acne is due to the activity of Propionibacterium acnes bacteria. Pidada Merah leaves are one of the plants that contain antibacterial compounds. It is said to contain compounds as antibacterial because it contains secondary metabolites including flavonoids, alkaloids, tannins, saponins, and phenols. The purpose of this study was to determine the antibacterial activity and the diameter of the inhibition zone of Pidada Merah leaf extract against the growth of Propionibacterium acnes.This type of research is not experimental using the well method. This study was divided into seven groups; the extract group with various concentrations (20%, 40%, 60%, and 80%), the positive control group (clindamycin 0.1%) and the negative control group (Aquadest). The results showed that the Pidada Merah leaf extract had antibacterial activity against the growth of Propionibacterium acnes. The diameter of the inhibition zone formed at concentrations of 20%, 40%, 60%, and 80%, respectively 11.51 mm (strong), 11.73 mm (strong), 12 mm (strong), 12.4 mm (strong).
KETEPATAN PENGGUNAAN TURBUHALER DAN TINGKAT KONTROL ASMA PADA PASIEN ASMA: STUDI POTONG LINTANG DI RS X Sri Suprapti; Nurul Kusumawardani; Rizal Fauzi; Ishak; Fitriah Ramadani; Widhowati Destiathree Supardi; Emelda
Jurnal Insan Farmasi Indonesia Vol 9 No 1 (2026): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/s8n1n127

Abstract

Asthma is a chronic inflammatory disease requiring long-term inhalation therapy. Treatment success depended on both the prescribed medication and the correct use of the inhaler. This study aimed to evaluate the accuracy of the Turbuhaler technique and its association with asthma control. A prospective cross-sectional study was conducted among 39 adult outpatients using a Turbuhaler at a hospital in Yogyakarta, Indonesia. Inhaler technique was evaluated using a checklist, and asthma control was assessed with the Asthma Control Test (ACT). The association was analyzed using Fisher's exact test. The results showed that 76.92% of patients used the Turbuhaler incorrectly and that 79.49% did not achieve asthma control. A significant association was found between correct technique and asthma control (p < 0.001), with a prevalence ratio of 9.00 (95% confidence interval [CI], 1.42–57.12). Patients who performed the technique correctly were nine times more likely to achieve control. The most frequently missed steps were holding one's breath after inhaling, rinsing one's mouth, and taking a deep breath. Correct Turbuhaler technique is a key determinant of asthma control. Pharmacist-led education focusing on these critical steps is essential to optimize treatment outcomes and prevent adverse effects.
Analisis Hubungan Tekanan Darah dan Penyakit Penyerta terhadap Kualitas Hidup Pasien Hipertensi Abdul Mahmud Yumassik; Muhammad Faqih; Fitrah Shafran Ilahi; Nordin; Anshar Timur Samudra; Noor Aisyah
Jurnal Insan Farmasi Indonesia Vol 9 No 1 (2026): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/xfx5f967

Abstract

Hypertension is a chronic condition that may reduce patients’ quality of life, particularly when accompanied by uncontrolled blood pressure and comorbid diseases. This study aimed to assess the quality of life of patients with hypertension and to analyze the relationship between blood pressure, comorbidities, and quality of life. A cross-sectional study design was used, with prospective data collection using the SF-6D instrument. A total of 305 respondents who visited the North Banjarmasin Public Health Center and met the inclusion criteria were selected using consecutive sampling. Quality of life was calculated using the SF-6D index calculator, while the relationship between variables was analyzed using the Pearson Chi-Square test. The results showed that the mean utility score of hypertensive patients receiving treatment was 0.7835. Statistical analysis indicated a significant association between quality of life and blood pressure, with p=0.016, as well as between quality of life and comorbidities, with p=0.037. Therefore, blood pressure and comorbidities are associated with the quality of life of patients with hypertension.
TINJAUAN NARATIF EFEKTIVITAS DAN KEAMANAN ANTIRETROVIRAL PADA PASIEN DENGAN KOINFEKSI HIV-HBV Rizky Yuliatus Solicha; Vitarani Dwi Ananda Ningrum
Jurnal Insan Farmasi Indonesia Vol 9 No 1 (2026): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/phqp4b95

Abstract

HIV-HBV coinfection remains a major global health challenge associated with increased morbidity and mortality. Various studies have evaluated the effectiveness and safety of antiviral therapies in coinfected patients; however, the findings remain inconsistent. This narrative review aimed to summarize the current evidence regarding the effectiveness and safety of antiretroviral therapy in patients with HIV-HBV coinfection. Literature searches were conducted through PubMed and Google Scholar for studies published between 2014 and 2025 using keywords related to HIV, hepatitis B, nucleos(t)ide analogues, interferon alfa, effectiveness, and safety. The findings demonstrated that the TLD regimen (tenofovir, lamivudine, and dolutegravir) showed superior virological outcomes compared with TLE (tenofovir, lamivudine, and efavirenz), including higher viral suppression rates and greater CD4 cell recovery. Nucleos(t)ide analogues such as entecavir and telbivudine effectively reduced HBV DNA levels and improved liver function markers. However, several adverse drug reactions were reported, including dizziness, nausea, vomiting, metabolic disturbances, and renal impairment, particularly with tenofovir-containing regimens. Interferon alfa also demonstrated potential benefits in enhancing seroconversion. Overall, TLD is considered the preferred regimen due to its superior efficacy and resistance profile, although careful monitoring for adverse effects remains essential.
STUDI TENTANG PENGGUNAAN TUMBUHAN OBAT OLEH MASYARAKAT SUKU MUNA DI PULAU MUNA, SULAWESI TENGGARA Rimala Sanipurnama Kindkasman; Djoko Santosa; Nanang Fakhrudin; Akhmad Riski
Jurnal Insan Farmasi Indonesia Vol 9 No 1 (2026): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/vpdg3a81

Abstract

The use of medicinal plants still plays an important role in traditional medicine practices in Indonesia, including in the Muna Tribe on Muna Island, Southeast Sulawesi. This research aims to identify the types of medicinal plants used, the parts of the plants used, the processing methods, and the types of diseases treated based on the local genius of the community. The research method used was snowball sampling technique, with data collection through interviews with the Muna Tribe using questionnaires. The question includes information about the type of disease, herb or single plant used, local name, part used, and the method of treatment. Each mentioned plant is then identified through a determination process to obtain its Latin name, and is documented in the form of a herbarium. The results of the study show that Muna Tribe on Muna Island, Southeast Sulawesi Province, has used as many as 29 plant species from 18 families as medicinal ingredients. The most dominant part of the plant used is the leaves. The most common method of using plants or herbs is boiled, the boiled water is drunk. This method is the most commonly applied practice by the local community in using plants as traditional medicine.
STUDI PENAMBATAN MOLEKUL SENYAWA METABOLIT SEKUNDER EKSTRAK AKAR TAWAR SERIBU (Bauhinia purpurea L) SEBAGAI POTENSI INHIBITOR  α-Glukosidase Nurul Fajeriyati; Rizka Mulya Miranti; Yulianita Pratiwi Indah Lestari
Jurnal Insan Farmasi Indonesia Vol 9 No 1 (2026): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/kmrfn388

Abstract

Diabetes mellitus is a disease characterized by elevated blood glucose levels due to impaired insulin secretion or action. A therapeutic development strategy involves inhibiting the α-glucosidase enzyme. Bauhinia purpurea, L. is known to contain various compounds with potential antidiabetic activity. This study aims to investigate the potential of secondary metabolites from Bauhinia purpurea, L. extract as α-glucosidase inhibitors using an in silico molecular docking approach and ADMET prediction. Test compounds were obtained from LC-MS identification results, and their three-dimensional structures were downloaded from the PubChem database. The protein structure was obtained from the Protein Data Bank (PDB ID: 3L4W). The molecular docking process utilized the AutoDock Tools software, yielding a validation result of 1.9 Å. The results showed ΔG values ranging from -4.00 kcal/mol to -8.26 kcal/mol. ADMET prediction results indicated high HIA values >90%, Caco2 permeability in the low permeability category (<4 nm·s⁻¹), low BBB values, and AMES test results classified as non-mutagenic for all test compounds. Based on these results, the secondary metabolites contained in the Bauhinia purpurea, L. extract show potential as α-glucosidase inhibitors with favorable pharmacokinetic parameters, making them suitable for development into drug candidates through pharmaceutical or chemical structural modifications.
BEYOND THERAPEUTIC BENEFITS: KAJIAN FARMAKOVIGILANS EFEK SAMPING KORTIKOSTEROID DI INDONESIA Senya Puteri Amalia; Farida Istiqamah; Nur Ainah; Desy Ayu Lestari
Jurnal Insan Farmasi Indonesia Vol 9 No 1 (2026): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/vv82rt22

Abstract

Corticosteroids are widely used in clinical practice in Indonesia for the treatment of various diseases. However, prolonged and/or high-dose corticosteroid therapy may lead to serious adverse effects that negatively affect patients’ quality of life. Monitoring of corticosteroid-related adverse drug reactions in Indonesia remains limited, highlighting the need for a pharmacovigilance approach to identify, assess, monitor, and prevent undesirable drug-related events. This review aimed to provide a comprehensive overview of adverse effects associated with corticosteroid use in Indonesia as a basis for safe, effective, and rational therapeutic decision-making. Literature searches were conducted through ScienceDirect, PubMed, Google Scholar, and manual searches using the keywords “pharmacovigilance,” “corticosteroid,” “side effect,” “adverse effect,” and “Indonesia” based on predefined inclusion and exclusion criteria. A total of eight eligible articles were critically analyzed, covering various corticosteroid dosage forms, patient characteristics, and the types and severity of adverse effects. The findings showed that adverse reactions ranged from mild to severe, with increased risk associated with long-term and high-dose corticosteroid use. This review emphasizes the importance of pharmacovigilance in improving healthcare professionals’ awareness and promoting rational corticosteroid use in Indonesia

Page 36 of 36 | Total Record : 358

 32   33   34   35   36 

Filter by Year

2018 2026


Reset
Filter By Issues
All Issue Vol 9 No 1 (2026): Jurnal Insan Farmasi Indonesia Vol 8 No 2 (2025): Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia Vol 6 No 1 (2023): Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia Vol 4 No 2 (2021): Jurnal Insan Farmasi Indonesia Vol 4 No 1 (2021): Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019) Vol 2 No 1 (2019) Vol 1 No 2 (2018) Vol 1 No 1 (2018) More Issue