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Jurnal Farmasi
Published by Sekolah Tinggi Ilmu Kesehatan Nasional
ISSN : 23027436     EISSN : 26568950     DOI : https://doi.org/10.37013/jf
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
JURNAL FARMASI (Journal Of Pharmacy) adalah jurnal ilmiah resmi yang dikeluarkan oleh Sekolah Tinggi Ilmu Kesehatan Nasional dengan nomor p-ISSN 2302-7436 e-ISSN 2656-8950. JURNAL FARMASI (Journal Of Pharmacy) berisikan jurnal-jurnal ilmiah dalam semua aspek ilmu pengetahuan dan teknologi di bidang Farmasi dan kesehatan antara lain: Farmakognosi dan Fitokimia meliputi Pengembangan Simplisia, Budidaya Tanaman Obat, Isolasi, Skrining Fitokimia, dan Identifikasi Obat Bahan Alam Indonesia. Biologi meliputi Biologi Molekuler, Bioteknologi, Mikrobiologi, Immunologi, Parasitologi, Biomedisinal Teknologi Farmasi meliputi Farmasetika, Teknologi dan Formulasi Sediaan Obat, Teknologi dan Formulasi Sediaan Obat Bahan Alam Indonesia. Ilmu Kimia meliputi Kimia Analisa, Kimia Organik, Sintesa Obat, Kimia Medisinal, Pemodelan Molekul, Biokimia, dan Kimia Lingkungan. Farmakologi meliputi Farmakologi, Farmakokinetik, Farmakoterapi, dan Toksikologi. Farmasi Klinik dan Komunitas meliputi Farmakoekonomi, Farmakovigilan, Analisis dan Evaluasi Penggunaan Obat, Monitoring Efek Samping Obat, Analisa Kebijakan Kefarmasian, Evaluasi kegiatan Kefarmasian, Evaluasi Efektifitas Penggunaan Obat, Evaluasi Kualitas Hidup Pasien.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 189 Documents
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GAMBARAN TINGKAT PENGETAHUAN SWAMEDIKASI VITAMIN C MAHASISWA D-III FARMASI STIKES WIDYA DHARMA HUSADA TANGERANG PADA PANDEMI COVID-19 TAHUN 2022 Dwi Krisiyowati, Anis
Jurnal Farmasi (Journal of Pharmacy) Vol. 12 No. 1 (2023): Jurnal Farmasi (Journal of Pharmacy), April 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/pjwke876

Abstract

Vitamin C is an essential water-soluble vitamin that is widely used as a body supplement. Misuse of the dosage will cause unwanted side effects such as nausea vomiting, diarrhea, increasing the risk of diabetes. This study is to find out an overview of the level of knowledge on self-medicating the use of vitamin C for D III Pharmacy students of STIKes Widya Dharma Husada Tangerang during the Covid-19 pandemic. This study is a descriptive study with 96 respondents taken by the cross- sectional method. Data were obtained through questionnaires and analyzed using percentages. The results obtained in this study are the characteristics of respondents based on age Most of them are found at the age of 17-25 years, namely 87.5%, based on gender Most of them are found in women, namely 84.37%, based on work more than half of them are found in those who are not working, namely 52.08%, and based on a history of exposure to covid-19 more than half of them are found in those who have been exposed to covid-19, namely 73.96%, while the characteristics of respondents' knowledge about the use of well-informed vitamin C were highest based on the age of 17-25 years as much as 84.37%, in the female sex as much as 81.25%, in unemployed work as much as 50%, in the history of exposure to covid-19 who had been exposed to covid-19 as much as 70.83%. Conclusion: The results of this study show that the concentration of the level of knowledge on self-medicating the use of vitamin C for D III Pharmacy students of STIKes Widya Dharma Husada Tangerang during the Covid-19 pandemic was 96.88% included in the "Good" category.
Hubungan Usia dan Konsumsi Makanan Berlemak dengan Kolesterol Total Pada Lansia Kelurahan Serengan Surakarta Cisillia Adhiyani
Jurnal Farmasi (Journal of Pharmacy) Vol 2, No 1 (2013): Oktober
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v2i1.15

Abstract

Masa lanjut usia membawa penurunan fisik dan kecenderungan angka kesakitan meningkat, salah satunya penyakit jantung koroner. Penyakit ini menjadi penyebab utama dari total kematian penduduk Indonesia dan salah satu faktor resikonya adalah hiperkolesterolemia. Hiperkolesterolemia dipengaruhi diet, keturunan, usia, jenis kelamin, obesitas, stress, alkohol, dan aktivitas fisik. Penelitian ini bertujuan untuk mengetahui hubungan usia dan konsumsi makanan berlemak dengan kolesterol total. Jenis penelitian analitik deskriptif dengan pendekatan cross sectional. Metode sampling menggunakan purposive sampling. Data penelitian dianalisis dengan program SPSS versi 16.0  Jumlah lansia laki-laki  13 orang dan lansia perempuan 88 dari total lansia n=101 orang. Lansia perempuan cenderung memiliki kolesterol total meningkat sejumlah 28 orang  daripada laki-laki. Kisaran umur 55-64 tahun memiliki kadar kolesterol meningkat ada 16 orang dibandingkan umur lainnya. Lansia gemar konsumsi makanan berlemak memiliki kadar kolesterol total meningkat ada 21 orang, lansia yang tidak gemar konsumsi makanan berlemak ada 8 orang yang meningkat kolesterol totalnya. Hasil pemeriksaan kolesterol total terhadap 101 sampel darah didapat kadar terendah 107 mg/dl dan tertinggi 301 mg/dl dengan rata-rata 184 mg/dl. Lansia dengan resiko sedang PJK ada 19 orang dan resiko tinggi PJK ada 10 orang berdasarkan hasil kolesterol totalnya. Hasil analisis statistik disimpulkan tidak terdapat hubungan  signifikan usia dengan kolesterol total (p=0.067; α=0.05), tidak terdapat hubungan signifikan konsumsi makanan berlemak dengan kolesterol total (p=0.057; α=0.05) dan tidak terdapat hubungan signfikan usia, konsumsi makanan berlemak dengan kolesterol total (p=0.185; α=0.05)
Analisis Pengaruh Pelaksanaan Standar Pelayanan Kefarmasian Terhadap Kepuasan Pasien Pada Program Rujuk Balik di Kota Yogyakarta Novi Dwi
Jurnal Farmasi (Journal of Pharmacy) Vol 4, No 1 (2015): Oktober
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v4i1.31

Abstract

Standar pelayanan kefarmasian sebagai acuan pelaksanaan pelayanan kefarmasian di apotek ditujukan untuk meningkatkan mutu pelayanan kefarmasian.Rujuk Balik merupakan salah satu program BPJS kesehatan untuk penderita penyakit kronis. Obat program ini diambil di apotek diluar biaya kapitasi.Karakteristik individu berhubungan dengan kepuasan. Penelitian ini bertujuan untuk mengetahui pengaruh pelaksanaan standar pelayanan kefarmasian terhadap kepuasan pasien di apotek pada program rujuk balik dan hubungan antara karakteristik dengan kepuasan pasien. Penelitian ini merupakan penelitian deskriptif analitik dengan metode pengumpulan data dilakukan dengan cara survey.Data diperoleh melalui kuesioner yang berisi karakteristik responden, persepsi responden terhadap pelaksanaan standar pelayanan kefarmasian dan kepuasan  Penelitian, dilengkapi data kualitatif hasil wawancara tentang pendapat dan masukan. Lokasi penelitian di apotek Rujuk Balik di Kota Yogkakarta yang berjumlah 4 lokasi dengan sampel yang digunakan sebanyak 101 responden yang terbagi secara proporsional. Terdapat pengaruh pelaksanaan standar pelayanan kefarmasian terhadap kepuasan pasien di Apotek pada Program Rujuk Balik. Pengaruh signifikan pada aspek pelayanan farmasi klinis (p=0,000) dan sumber daya kefarmasian (p=0,000) sedangkan aspek pengelolaan barang tidak berpengaruh secara signifikan terhadap kepuasan (p=0,436). Karakteristik pasien yang berhubungan dengan kepuasan adalah umur dan jarak antara tempat tinggal dengan apotek, sedangkan karakteristik jenis kelamin, pendidikan, pekerjaan, penyakit tidak berhubungan dengan kepuasan pasien.
PENGARUH RASIONALITAS PENGGUNAAN ANTIHIPERTENSI DENGAN STANDART GUIDELINE JNC 8 TERHADAP KEBERHASILAN TERAPI HIPERTENSI DI RS PANTI WALUYO SURAKARTA Dian Anggraini, Truly; Wisnu Kusuma, Eka; Diandari, Deswinda
Jurnal Farmasi (Journal of Pharmacy) Vol. 6 No. 1 (2017): Jurnal Farmasi (Journal of Pharmacy), October 2017
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Hypertension is one of the main problems of public health in the whole world and a factor tersering the risks of cardiovascular diseases .The prevalence of hypertension in the population of 18 years and older age of 29,8 % .An epidemiological data shows that a rise in blood pressure will increase the cardiovascular diseases, must be treated with proper and hypertension. The study aimed to identify the influence of rationality use of antihypertensives to the standard guideline jnc 8 to successful therapy hypertension in the hospital at waluyo surakarta year 2016 . The research is research cohort where over the withdrawal of funds data was undertaken in the manner of a retrospective from the records of record medical exam patients hypertension as an in patient in the year 2016 .After the recent retrieval of so sample will be analyzed the usage patterns antihypertensive drug as well as rationality the use of antihypertensive drug with a standard guideline jnc 8 have been analyzed in the manner of a diskriptif, the influence of rationality the use of antihypertensive drug with a standard guideline jnc 8 to successful ( therapy the point of view of achieve the target of the pressure of the blood patients ) have been analyzed is statistically use chi-square. The results of the study , 84 patients get therapy hypertension that is rational in accordance with guideline jnc 8 and 16 patients get therapy hypertension that is irrational with guideline jnc 8. The pattern of an antihypertensive drug, 52 patients prescribed an antihypertensive drug only begotten or unique son, 43 patients a combination 2 an antihypertensive dru , this is more than the patients prescribed more than 2 antihypertensive drug .The success of thera, 65 the patient from 84 cases of patients who get therapy hypertension that is rational managed to reach the target the pressure of the blood and he received treatment therapy assessed as being successful. A significant relation exists between rationality therapy hypertension with guideline jnc 8 against ketercapaian the success of therapy ( p<0,05 ).
Uji Penentuan Nilai SPF (Sun Protection Factor) Fraksi Bunga Rosela (Hibiscus Sabdariffa L.) Sebagai Zat Aktif Tabir Surya Nopiyanti, Vivin; Aisiyah , Siti
Jurnal Farmasi (Journal of Pharmacy) Vol. 9 No. 1 (2020): Jurnal Farmasi (Journal of Pharmacy), April 2020
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Sun Protection Factor or SPF is defined as the ratio between the amount of sunlight energy (in this case UV-B) needed to cause minimal erythema on sun-protected skin with the amount of energy needed to cause minimal erythema on skin that is not protected by sunscreen. Rosela flowers contain flavonoids, anthocyanes, and polyphenols. Flavonoids compound have the potential as sunscreens because they have a chromophore group (single conjugated double bond) that is able to absorb UV-A and UV-B rays so that it reduces the intensity of the skin. This research was conducted to find out the SPF value of the n-hexane fraction, the ethyl acetate fraction and the water fraction from the rosela flower. And it is known that the faction that has the highest SPF value can be used as sunscreen. Rosela flower extract then fractionated with n hexane, ethyl acetate and water solvents. The resulting fractions in the form of n-hexane fraction, ethyl acetate fraction and water and extract fractions were measured for their SPF values. SPF measurements can be done in vitro using UV-Vis spectrophotometry. In vitro testing was useful for preliminary tests in the process of developing sunscreen products. The SPF value of the extract, the n-hexane fraction, the ethyl acetate fraction and the water fraction from the rosela flower extract, respectively 6,63±0,23; 10,11±0,61; 13,83±1,50; 11,15±0,47. The ethyl acetate fraction was the fraction that has the highest SPF value that can be used as a sunscreen.
Pengaruh Metode Ekstraksi Terhadap Kadar Total Fenolik dan Kadar Total Flavonoid Daun Talas (Colocasia esculenta L.) Septiana Laksmi Ramayani; Devi Hildhania Nugraheni; Antonius Robertin Evan Wicaksono
Jurnal Farmasi (Journal of Pharmacy) Vol 10, No 1 (2021): Maret
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v10i1.115

Abstract

Daun talas (Colocasia esculenta L.) diketahui dapat digunakan sebagai antidiabetes, karena adanya kandungan senyawa bioaktif senyawa fenolik dan flavonoid. Aktivitas farmakologis suatu ekstrak bergantung pada kadar senyawa aktif yang terkandung, semakin besar kadar senyawa maka semakin tinggi pula aktivitasnya. Metode ekstraksi mempengaruhi konsentrasi atau hilangnya efek terapi dari simplisia karena beberapa simplisia bersifat relatif tidak stabil dan dapat terurai. Tujuan penelitian ini adalah mengetahui pengaruh perbedaan metode ekstraksi terhadap kadar total senyawa fenolik dan kadar total senyawa flavonoid ekstrak daun talas. Ekstraksi daun talas menggunakan pelarut etanol 96% menggunakan metode maserasi, Microwave Assisted Extraction (MAE) dan sokletasi. Penetapan kadar total senyawa Fenolik menggunakan metode Folin Ciocalteau dengan baku pembanding asam galat. Penetapan kadar total flavonoid menggunakan metode kolorimetri dengan pereaksi AlCl3 dan baku pembanding kuersetin. Metode ekstraksi berpengaruh signifikan terhadap kadar total fenolik dan kadar total flavonoid ekstrak daun talas dengan nilai p<0,05. Kadar total fenolik dan kadar total flavonoid tertinggi pada metode ekstraksi sokletasi yaitu sebesar 10,39 mgGAE/g ekstrak dan 12,44 mgKE/g ekstrak.
Penetapan Kadar Metilparaben dan Propilparaben dalam Hand and Body Lotion secara High Performance Liquid Chromatography Dhurhania, Crescentiana Emy
Jurnal Farmasi (Journal of Pharmacy) Vol. 1 No. 1 (2012): Jurnal Farmasi (Journal of Pharmacy), October 2012
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Metilparaben dan Propilparaben merupakan bahan antibakteri dan antifungi yang efektif. Banyak produk kosmetik menggunakan metilparaben dan propilparaben sebagai bahan pengawet, salah satunya adalah hand and body lotion. Keputusan Kepala Badan Pengawas Obat dan Makanan (POM) Republik Indonesia No.HK.00.05.1745, tanggal 5 Mei 2003 tentang kosmetik menyebutkan bahwa batas maksimum kadar metilparaben dan propilparaben adalah 0,4 % sebagai pengawet tunggal dan 0,8 % sebagai pengawet campuran. Namun berdasarkan pengamatan penulis, produsen hand and body lotion tidak mencantumkan kadar metilparaben dan propilparaben pada labelnya. Penelitian inii dilakukan untuk mengetahui kadar metilparaben dan propilparaben yang digunakan dalam hand and body lotion dan untuk mengetahui apakah kadar tersebut memenuhi persyaratan yang ditentukan. Penelitian ini merupakan penelitian non eksperimental deskriptif, menggunakan metode High Performance Liquid Chomatography (HPLC) fase terbalik dengan kolom Water Novopac C18, fase gerak metanol : akuabides (4:6), kecepatan alir 1,2 ml/menit, dan detektor UV 257 nm. Parameter yang digunakan untuk menyatakan validitas metode analisis adalah selektivitas, akurasi, presisi, linieritas, batas deteksi dan batas kuantitasi. Hasil validasi metode analisis menunjukkan bahwa metode HPLC dapat dinyatakan valid untuk analisis metilparaben dan propilparaben dalam hand and body lotion. Berdasarkan analisis hasil yang dilakukan pada taraf kepercayaan 95 %, diperoleh bahwa ketiga hand and body lotion yang digunakan pada penelitian ini mengandung metilparaben dan propilparaben dengan kadar rata-rata sebagai berikut : sampel merk “A” adalah (0,24 ± 0,003)%;merk “B” adalah (0,19 ± 0,004)%; dan merk “C” adalah (0,08 ± 0,001) % untuk propilparaben. Dengan demikian kadar metilparaben dan propilparaben dalam ketiga merk hand and body lotion, baik dinyatakan sebagai kadar masing-masing maupun kadar jumlah, masih memenuhi persyaratan yang telah ditentukan oleh Badan POM
Penelusuran Potensi Aktivitas Antibakteri dan Antioksidan Fraksi Kulit Pohon Faloak (Sterculia quadrifida R.Br) Rollando Rollando
Jurnal Farmasi (Journal of Pharmacy) Vol 4, No 1 (2015): Oktober
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v4i1.26

Abstract

Penduduk Nusa Tenggara Timur memanfaatkan kulit batang tumbuhan Faloak (Sterculia quadrifida R.Br.) sebagai tumbuhan obat untuk mengobati penyakit liver, gastroentritis, dan penambah stamina. Kulit batang Faloak mengandung senyawa fenol, flavonoid, dan terpenoid. Penelitian ini bertujuan menganalisis daya antibakteri dan antioksidan dari fraksi hasil pemisahan ekstrak etanol kulit Faloak. Fraksi 3 menunjukan aktivitas antibakteri yang tinggi (IC50) pada bakteri B. subtilis (90.51 µg/mL), E. coli (80.12 µg/mL), S.aureus (77,87 μg/mL), dan S.thypi (61.23 µg/mL). Uji aktivitas antioksidan menunjukan bahwa fraksi 2 mempunyai aktivitas antioksidan dan kandungan fenolik total yang paling tinggi (34,16 ± 0,76 mg GAE).
PENGARUH TiO2 DAN pH PADA FOTOREDUKSI ION Cu(II) DALAM LARUTAN YANG MENGANDUNG PARACETAMOL Ingrid A, Devina; Angeliasari , S.
Jurnal Farmasi (Journal of Pharmacy) Vol. 5 No. 1 (2016): Jurnal Farmasi (Journal of Pharmacy), October 2016
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Research on photoreduction of Hg(II) solution containing p-chlorophenol has been done. In photocatalitic approach, this study tried to overcome environmental problem due to Hg-polluted water that is still a seriuous problem now. Photocatalist material, such as TiO2 have been developed to support the effort in solving such a problem. One of negative impact of industrial development is disposal of waste water generated from industrial activities. Industrial waste water may contain inorganic and organic chemicals. Anorganic waste such as Cu(II) in the aquatic environment has a threshold of 1 mg/L that present together with organic waste such as paracetamol. This study is purposed to determine the effect of TiO2 mass and pH, and optimum conditions of TiO2 catalyzed Cu(II) photoreduction effectiveness. Photocatalysis combines ultraviolet irradiation and semiconductor particles as photocatalysts in chemical proccess. Cu(II) photoreduction process was conducted in a closed reactor equipped with a magnetic stirre and UV lamp black light blue (BLB). After process solution was then analyzed by Atomic Absorption Spectrophotometer (AAS) to determine the remaining Cu(II) concentration and visible spectrophotometer to determine the remaining paracetamol. Results show that Cu(II ion was reduced increasingly withy mass of TiO2. Within TiO­2 range of 20 to 25 mg Cu(II) reduction increase moderately, TiO2 mass of 30 to 50 mg was reduction was decreased. Variation of solution pH, within pH 3 to 5 shows the reduction occure effectively, while it would decrease at pH 5 to 11. Reaction conditions that produce the the most effective process are pH 5, Cu(II) concentration of 10 mg/L 25 mL, with the addition of 25 mL paracetamol 300 mg/L, TiO­2 of 25 mg, with irradiation time of 30 minutes. In these conditions Cu(II) ion was reduce effectively by 98.70% and paracetamol degraded by 14.61%.
Pemberian Metode Progressive Muscle Relaxation Exercise Terhadap Kadar Hemoglobin (Hb) pada Remaja Putri Amarseto, Binuko; Ariyanti, Lilik; Awanis, Almas
Jurnal Farmasi (Journal of Pharmacy) Vol. 8 No. 1 (2019): Jurnal Farmasi (Journal of Pharmacy), October 2019
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Teenage age is a transition from childhood to adulthood. In adolescence many changes occur, namely physical changes due to increased muscle mass, increased fat tissue in the body, hormonal changes also occur. Adolescent girls are one of the groups who are prone to suffering from iron nutritional anemia due to menstruation or periodic periods that release iron every month. One technique for relaxation is PMR Jacobson's technique. PMR according to Jacobson is a skill that is learned and used to reduce or eliminate tension and cause a sense of comfort without depending on the subject outside himself. PMR is used to reduce anxiety, stress, or tension.This study aims to determine the effect of the provision of progressive muscle relaxation exercise methods on hemoglobin (Hb) levels in young women. This research is a pre-experimental study using a one group pretest-posstest design. Data collection was carried out using a questionnaire. The research sample is adolescents, amounting to 90 people using simple random sampling technique. Data analysis using the Wilcoxon test with a significance level of 5%.The results of the study found that the highest number of respondents was the 10 study groups with 32 respondents (35.6%) while the number of respondents in the 11 study groups was 30 respondents (33.3%) and the most 12 study groups consisted of 28 respondents (31.1%) . showed that there was an effect of the administration of progressive muscle relaxation exercise methods to hemoglobin (Hb) levels in adolescent girls (p <0.05). From the results of this study it can be concluded that progressive muscle relaxation exercise can increase the influence of hemoglobin (Hb) levels in adolescent girls. Physical activity can affect hemoglobin levels because the nutrients consumed enter the body are assisted by the process for the formation of hemoglobin (Hb).

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