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Novena Yety Lindawati
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Jurnal Farmasi
Published by Sekolah Tinggi Ilmu Kesehatan Nasional
ISSN : 23027436     EISSN : 26568950     DOI : https://doi.org/10.37013/jf
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
JURNAL FARMASI (Journal Of Pharmacy) adalah jurnal ilmiah resmi yang dikeluarkan oleh Sekolah Tinggi Ilmu Kesehatan Nasional dengan nomor p-ISSN 2302-7436 e-ISSN 2656-8950. JURNAL FARMASI (Journal Of Pharmacy) berisikan jurnal-jurnal ilmiah dalam semua aspek ilmu pengetahuan dan teknologi di bidang Farmasi dan kesehatan antara lain: Farmakognosi dan Fitokimia meliputi Pengembangan Simplisia, Budidaya Tanaman Obat, Isolasi, Skrining Fitokimia, dan Identifikasi Obat Bahan Alam Indonesia. Biologi meliputi Biologi Molekuler, Bioteknologi, Mikrobiologi, Immunologi, Parasitologi, Biomedisinal Teknologi Farmasi meliputi Farmasetika, Teknologi dan Formulasi Sediaan Obat, Teknologi dan Formulasi Sediaan Obat Bahan Alam Indonesia. Ilmu Kimia meliputi Kimia Analisa, Kimia Organik, Sintesa Obat, Kimia Medisinal, Pemodelan Molekul, Biokimia, dan Kimia Lingkungan. Farmakologi meliputi Farmakologi, Farmakokinetik, Farmakoterapi, dan Toksikologi. Farmasi Klinik dan Komunitas meliputi Farmakoekonomi, Farmakovigilan, Analisis dan Evaluasi Penggunaan Obat, Monitoring Efek Samping Obat, Analisa Kebijakan Kefarmasian, Evaluasi kegiatan Kefarmasian, Evaluasi Efektifitas Penggunaan Obat, Evaluasi Kualitas Hidup Pasien.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 189 Documents
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HUBUNGAN ANTARA ANEMIA DAN PRESTASI BELAJAR DENGAN INDEKS MASSA TUBUH PADA REMAJA PUTRI KELAS VIII DI SURAKARTA Widhiyastuti, Endang
Jurnal Farmasi (Journal of Pharmacy) Vol. 6 No. 1 (2017): Jurnal Farmasi (Journal of Pharmacy), October 2017
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Adolescents aged 13-15 years old were transition from early adolescence to late adolescence which is a period of identity search so easily affected the surrounding environment. Therefore, adolescents at high risk of nutritional disorders because in adolescents experienced increased nutritional needs, the habit of limiting the consumption of food and consumption patterns that often deviate from the rules of nutrition science.Status nutrition and anemia are factors that affect the development of the brain. Brain damage due to nutritional disturbances leads to cognitive impairment, impaired IQ development and impaired learning abilities that subsequently affect learning achievement. Objective: This study aims to determine the correlation between anemia and learning achievement with body mass index (BMI) in adolescent girls of class VIII in Surakarta. Research method: The research design used was observational with cross sectional approach, the population of junior high school girls 3 and SMP Negeri 7 Surakarta even semester of 2015/2016, aged 13-15 years. Research subjects amounted to 120 taken by random sampling. Data obtained through questionnaire, nutritional status measured by z-score. Anemia was measured by Hb levels using cyanmethemoglobin method. Learning achievement is measured from the final exam score. Furthermore, the collected data is processed by using bivariate analysis. Result of research: The value of r = 0,201, odd ratio 4,255 and p = 0,35, this means there was correlation between anemia with body mass indeks (IMT) in junior high school girl of class VIII in Surakarta. While the relation between learning achievement with IMT class of females VIII obtained r = 0.093 with odd ratio = 0,307 and p = 0999. This means there was no relationship between learning achievement and BMI. Conclusion: There is a significant relationship between BMI with anemia No relation between IMT and learning achievement.
Evaluasi Tindakan Aseptis Tenaga Teknis Kefarmasian pada Proses Rekonstitusi dan Penyimpanan Injeksi Antibiotik di Ruang Rawat Inap RS UNS Rahma Noviyanti, Eka; Murtisiwi, Lusia
Jurnal Farmasi (Journal of Pharmacy) Vol. 11 No. 1 (2022): Jurnal Farmasi (Journal of Pharmacy), April 2022
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/6k4vac70

Abstract

This study aims to evaluate the application of aseptic measures by Pharmaceutical Technical Personnel (TTK) during reconstitution and storage of antibiotics, including personal protective equipment (PPE), room and equipment, mixing process, and storage of antibiotic injections in the inpatient unit of UNS Hospital. This research is a non-experimental research with a descriptive design. Data collection was carried out by direct observation to health workers who carried out reconstitution and storage of antibiotic injections in the inpatient unit of UNS Hospital. The research sample was 49 respondents. The analysis in this study was carried out quantitatively by calculating the percentage of compliance with the Standard Operating Procedure (SOP) at the UNS Hospital Inpatient and then presented descriptively. The results showed that the process of reconstitution and storage of antibiotic injections in the inpatient installation of UNS Hospital was in accordance with the percentage of conformity of preparation procedures of 89%, mixing procedures of 82%, storage procedures of 90%, distribution procedures of 76%.
Tinjauan Pola Penggunaan Antibiotik Pada Pasien Anak Demam Tifoid di Instalasi Rawat Inap RSUP dr. Kariadi Semarang Tahun 2009 Dian Anggraini, Truly
Jurnal Farmasi (Journal of Pharmacy) Vol. 2 No. 1 (2013): Jurnal Farmasi (Journal of Pharmacy), October 2013
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Typhoid fever including one of disease the infection found many in developing countries with high density and also health of low environment. Pursuant to report WHO mentioned that Indonesia is one of the State with number occurence of high typhoid fever, that is > 100 per 100.000 resident per year. Epidemiology study is recently show to start the existence of risk multi drug resisten (MDR) at usage of antibiotic for the medication of typhoid fever. So that this research is done to know the pattern usage of antibiotic at typhoid fever child patient in Installation of Hospitalization RSUP Dr. Kariadi Semarang in the year 2009. This research is non-experimental. The data was collected retrospectively from patient medical records. Counted 100 sampel obtained, and the results were analyzed using descriptive non-analytic method. Patterns of use of antibiotics for typhoid fever seen through a class of antibiotics used, the presence or absence of antibiotics during replacement therapy, a combination of antibiotics given, route of administration, duration of antibiotics, antibiotic side effects, and drug interactions that occur due to the use of antibiotics. Research result indicate that at period of year of 2009 in Installation of Hospitalization RSUP Dr. Kariadi typhoid fever predominated by men patient at spanning the age of 6-10 year. The Antibiotic faction at most used is from faction sefalosporin equal to 55,22%, from 100 case of 35 between natural it’s of replacement antibiotic, usage of antibiotic combination equal to 50%, supply of antibiotic more given in the form of hypodermic and for the giving of antibiotic there are to don’t according giving of antibiotic at patient with written Standard Procedure Operational that is much more brief.
Formulasi dan Evaluasi Tablet Floating furosemida Gastroretentif Menggunakan Kitosan Dari Cangkang Keong Mas (Pomacea canaliculata) Setiawan, Iwan; Hartono
Jurnal Farmasi (Journal of Pharmacy) Vol. 4 No. 1 (2015): Jurnal Farmasi (Journal of Pharmacy), October 2015
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Chitosan is kind of a natural polymer which is a product of deacetylation of chitin which can be obtained from the shells of golden snails (Pomacea canaliculata). Gastroretentive drug delivery systems can help improve the bioavailability, can maintain contact time of the drug longer with the gastrointestinal mucosa cause bioavailability of the drug will be higher, the efficacy of therapy, reducing the time interval of drug administration, reduce therapeutic doses and will ultimately improve patient compliance. The objective of the present study was to develop and evaluate gastroretentive floating tablet of furosemida using chitosan of shell golden snails. Chitosan which is isolated from the shells of snails formulated as polymer concentration variation in the formula of making floating tablets furosemide. The results showed shells of snails obtained from chitosan yield of 10.8%. Furosemide tablets containing chitosan polymers produce good powder and meets the requirements include the flow time, angle of repose and compressibility index, uniformity of weight, hardness, friability and disintegration time. The Formulation F3 containing (Furosemide with the highest concentration of chitosan) was found to the best. The test results mainly floating tablet hardness and Buoyancy / floating test showed significantly different results with furosemide tablets containing no polymer chitosan. This suggests that the natural polymer chitosan derived from the shells of golden snails are potentially as the building blocks of making tablets with gastroretentive drug delivery systems.
Ancaman Zoonosis : Infeksi Plasmodium knowlesi pada Manusia Saroh, Dewi; Haryatmi, Dwi
Jurnal Farmasi (Journal of Pharmacy) Vol. 8 No. 1 (2019): Jurnal Farmasi (Journal of Pharmacy), October 2019
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Plasmodium knowlesi is one of the blood protozoa that can cause malaria. P. knowlesi initially only infected long-tailed macaques, but now it can cause zoonoses and infect humans. P. knowlesi can infect human body singly or mix infection with other parasites. This paper aims to provide a review of the morphology, prevalence, diagnosis, and treatment of P. knowlesi infections. The results of the review found that diagnosis of P. knowlesi can be established by PCR examination because diagnosis by microscopic can cause misidentification and lead to errors in diagnosis. Transmission of P. knowlesi to humans can occur through the bite of Anopheles Leucosphyrus Group mosquito. The prevalence of P. knowlesi to date has been found in the Southeast Asian region specifically in Malaysia. Treatment of malaria due to P. knowlesi without complications can be given with ACT therapy or with a combination of chloroquine and primaquine.
Penentuan Kadar Enzim Kolinesterase pada Petani Pengguna Pestisida Organofosfat Berdasarkan Frekuensi Penyemprotan Yoga Saputra, Devi; Purwati; Harningsih, Tri
Jurnal Farmasi (Journal of Pharmacy) Vol. 9 No. 2 (2020): Jurnal Farmasi (Journal of Pharmacy), October 2020
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Pesticides are generally interpreted as toxic chemicals that are used to control pests that harm humans. Pesticides have been used to increase agricultural production, plantations and eradicate disease vectors. The frequency of spraying and the high volume of pesticides used indicates the decisive role of these pesticides in crop production, these pesticides cannot be released from agricultural planting. Most farmers spray themselves and have their own sprayers so that they have the flexibility to spray. Vegetable growers have a high risk of pesticide poisoning. This research uses the literature study method. Data collection uses secondary data taken from scientific journals and scientific papers with the last 10 years vulnerable. Data analysis uses descriptive analysis. Cholinesterase enzyme is an enzyme found in celluloid fluid. It used to stop the action of acetylcholine by hydrolyzing into colin and acetic acid. Acetylcholine is an introductory nerve located in the entire central nervous system, autonomic nerve (sympathetic and parasymatic) and the somatic nervous system. The results of the study stated that 4 journals stated that there was a correlation between the frequency of spraying on the enzyme level cholinesterase, while 2 journals stated that there was no relationship. The frequency of spraying affects the decrease in the level of theenzyme cholinesterase in organophosphate pesticide farmers.
PERBANDINGAN KUALITAS AIR DI PULAU JAWA DAN KALIMANTAN (REVIEW JURNAL) Rida Yuliani; Witiyasti Imaningsih
Jurnal Farmasi (Journal of Pharmacy) Vol 9, No 1 (2020): Maret
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v9i1.101

Abstract

Ulasan mengenai kualitas air dari hasil penelitian di Pulau Jawa dan Kalimantan telah dilakukan untuk mendapatkan ilustrasi mengenai tingkat pencemaran air (air minum isi ulang, air PDAM, dan air sumur) oleh bakteri Coliform. Data diperoleh dari sumber sekunder berupa hasil penelitian dari beberapa daerah di Pulau Jawa dan Kalimantan. Hasil perbandingan kualitas air dari kedua pulau disajikan dalam bentuk persentase. Berdasarkan hasil yang ada, tingkat pencemaran air di Pulau Jawa lebih tinggi dibandingkan Pulau Kalimantan. Persentase rata-rata cemaran Coliform pada air di Pulau Jawa yaitu 61,42% dan hanya sebesar 42,26% di Pulau Kalimantan. Tingginya persentase cemaran air oleh bakteri Coliform di Pulau Jawa dikarenakan Pulau Jawa memiliki keberadaan sumber pencemar yang lebih tinggi. Keberadaan sumber Coliform dipengaruhi oleh jumlah penduduk dan perumahan serta produksi sampah organik.
Optimasi Kapsul Bawang Putih (Allium sativum Linn) sebagai Terapi Alternatif Pengobatan TBC Novena Yety Lindawati; Hartono Hartono
Jurnal Farmasi (Journal of Pharmacy) Vol 2, No 1 (2013): Oktober
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v2i1.16

Abstract

Bawang putih (Allium sativum Linn) terbukti aktif terhadap Mycobacterium tuberculosis. Senyawa alisin yang terkandung dalam bawang putih (Allium sativum Linn) berfungsi sebagai antimikroba spektrum luas yang mampu menghambat bakteri penyebab TBC. Kapsul bawang putih (Allium sativum Linn) harus memenuhi persyaratan sesuai dengan Keputusan Menteri Kesehatan Republik Indonesia No: 661/MENKES/SK/VII/1994 tentang persyaratan obat tradisional.  Hasil penelitian menunjukkan ekstrak bawang putih memiliki khasiat sama dengan bawang puting lanang, pada dosis 240 µg/ml medium (setara dengan 600 mg ekstrak bawang putih per kapsul) memiliki potensi paling besar dalam menghambat pertumbuhan Mycobacterium tuberculosis (diambil dari koloni biakan murni dari kultur sputum pasien yang menderita TBC jenis BTA +2,  kultur positif 9, resisten  terhadap rifampisin) dibanding dosis 320 dan 400 µg/ml media. Ekstrak kering bawang putih (Allium sativum Linn) memenuhi persyaratan sebagai bahan isi kapsul obat tradisional, antara lain angka lempeng total 1.5 (dipersyaratkan tidak lebih dari 10); angka kapang dan khamir ekstrak bawang putih 6.102 (dipersyaratkan tidak lebih dari 104); tidak mengandung mikroba patogen (tidak terkontaminasi bakteri coliform, Eschericia coli, Salmonella sp, dan Staphylococcus aureus); tidak terdeteksi adanya aflatoxin (dipersyaratkan tidak lebih dari 30 bpj); kadar air rata-rata sebesar 1 sampai 2 % (dipersyaratkan tidak lebih dari 10 %).  Kapsul ekstrak kering bawang putih (Allium sativum Linn) memenuhi persyaratan farmasetika untuk sediaan kapsul obat tradisional hasil uji waktu hancur kurang lebih 13 menit (dipersyaratkan tidak lebih dari 15 menit) dan memenuhi keseragaman bobot yang dipersyaratkan untuk sediaan kapsul.
Pengembangan Formula Gel Ekstrak Teh Hijau (Camellia sinensis L.) sebagai Penyubur Rambut Yety Lindawati, Novena; Murtisiwi, Lusia; C.E. Dhurhania
Jurnal Farmasi (Journal of Pharmacy) Vol. 3 No. 1 (2014): Jurnal Farmasi (Journal of Pharmacy), October 2014
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Hair loss is can be a fashionable matter. Green tea extract which the concentration is about 5% can stimulate hair growing (Sumakdjaja, et.al.,2008). The compound in green tea extract are catecine and their derivate. They are epicatecine (EC), epicatecine galat (ECG), and epigalocatecine (EGCG). In green tea axtract there are also contains galat acid, galocatecine galat (GCG), galocatecine (GC), catecine galat (CG), catecine (C), vitamin B and vitamin C (Agus, 2007) which can make hair root stronger, prefent hair loss, to inhibit free radical, neutralize poisson, and protect head skin from infection. People more interest to use cosmetics and foods with green tea extract. There is no hair growth stimulating gel with green tea extract in the market. This is the reason of this research, is to develope hair growth stimulating gel formula. There are four formula in this research. They are formula I (Carbopol 1%, TEA0 3%, and glycerine 1%), formula II (CMC Na 3% and glycerine 1%), formula III (PEG 400 72%, PEG 4000 8%, and glycerine 1%) and formula IV (carbopol 0,75%, TEA 2%, PEG 400 12%, and glycerine 1%). The concentration of green tea axtract in each formula are 5%. In each formula contains 0,1% nipagin as a preservative, and 0,1% sodium metabisulfit. The quality of each gel formula tested by organoleptic test, homogenity test, pH test, spread test, thickening test, protection test, primary iritation test, aceptability test, and hair growth stimulating activity test.
PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN SIRIH MERAH (Piper Crocatum Ruiz & Pav) TERHADAP EKSPRESI GLUKOSA TRANSPORTER 2 PADA HATI DAN PANKREAS YANG DIINDUKSI STREPTOZOTOCIN-NIKOTINAMIDA Wisnu Kusuma, Eka; Herowati, Rina; Nurrochmad, Arief
Jurnal Farmasi (Journal of Pharmacy) Vol. 6 No. 1 (2017): Jurnal Farmasi (Journal of Pharmacy), October 2017
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Diabetes mellitus is a metabolic disease characterized by hyperglycemia, decreased expression of GLUT-2 in pancreatic, and increased expression of GLUT-2 in liver. Red betel leaf seed is useful for treatment of diabetes. This study aims to determine the effect of antihyperglycemic, increased expression of GLUT-2 in pancreas, and decrease in liver of the red betel leaf ethanol extract in STZ-NA induced rats. This research used 25 male white wistar rats, which randomly divided into five groups, normal control, negative control, positive control, EEDSM dose of 50 mg/kg bw and 100 mg/kg bw. Induced STZ-NA days 0, measured glucose levels next day 5 and treated were for 14 days. Measured parameters were GLUT-2 expression in pancreas and liver. The results showed that EEDSM for 14 days qualitatively able to increase the expression of GLUT-2 in pancreatic cells with those in the normal control, negative control, positive control, EEDSM 50 mg/kg bw, and 100 mg/kg bw respectively to 100%, 32,31%, 67,67%, 52,73% and 60,01%. EEDSM qualitatively able to reduce the expression of GLUT-2 in liver cells with those in the normal control, negative control, positive control, EEDSM 50 mg/kg bw, and 100 mg/kg bw respectively to 13,21%, 100%, 52,05%, 87,08%, dan 78, 09%.

Page 8 of 19 | Total Record : 189

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