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INDONESIA
Jurnal Farmasi dan Sains Indonesia (JFSI)
Published by Sekolah Tinggi Ilmu Farmasi Nusaputera
ISSN : 26219360     EISSN : 26863529     DOI : https://doi.org/10.52216
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology Neuroscience
Focus and Scope Jurnal Farmasi & Sains Indonesia is an open-access journal that published twice a year by Sekolah Tinggi Ilmu Farmasi Nusaputera. This journal is a media of research publication on all aspects of pharmaceutical & science that is innovative, creative, original and based on scientific. Articles published in this journal about drug discovery, drug delivery systems and drug development with specific field include: 1. Medicinal chemistry 2. Pharmacology 3. Pharmacokinetics 4. Pharmacodynamics 5. Pharmaceutical analysis 6. Drug delivery systems 7. Pharmaceutical technology 8. Pharmaceutical biotechnology 9. Herbal medicines and active components 10. Clinical evaluation of the medicine
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 244 Documents
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FORMULASI DAN UJI AKTIVITAS KRIM ANTI AGING EKSTRAK DAUN SIRIH (Piper betle L.) DENGAN VARIASI KONSENTRASI GLISERIN DAN PROPILEN GLIKOL PADA KULIT PUNGGUNG KELINCI PUTIH NEW ZAELAND Wicaksono, Salsabila Melia Putri; Ekowati, Dewi; Handayani, Sri Rejeki
Jurnal Farmasi & Sains Indonesia Vol 5 No 2 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no2p38-47

Abstract

Aging is a natural event of living things caused by extrinsic factors, one of which is ultraviolet light. Aging causes human skin to become wrinkled. In this study, the formulation of an anti-aging cream preparation of betel leaf extract (Piper betle L.) and the anti-aging activity test on the back skin of white rabbits in New Zaeland will be carried out. In previous studies, researchers used extraction using methanol as a solvent. This study aims to determine the healing of wrinkles on the back skin of rabbits due to exposure to UV-A rays. The extraction method used is the maceration method. Betel leaf extract was tested for water content and chemical content. The betel leaf extract was made into a cream formulation and then tested for the physical quality of the cream, namely organoleptic, cream type, homogeneity, pH, spreadability, adhesion, viscosity, and stability. Primary and ocular irritation test and anti-aging activity test were perfomed on the backs of 5 rabbits with 5 treatments. The skin on the rabbit’s back was smeared with negative control cream, positive control cream, betel leaf extract cream with variations of glycerin 5% propylene glycol 15%, glycerin 10% propylene glycol 10%, glycerin 15% propylene glycol 5%. The results of the study obtained that the yield of betel leaf extract was 12.04%. For stability results on cream of betel leaf extract, it was found that all physical quality tests were stable. The results of the irritation test using the Draize method showed that the betel leaf extract cream did not irritate the skin. Anti-aging activity test showed that betel leaf extract cream with various concentrations of glycerin 10% propylene glycol 10% and glycerin 5% propylene glycol 15% was the most effective in reducing wrinkles on the rabbit’s back skin
Formulasi Dan Evaluasi Fisik Sediaan Salep Dari Variasi Ekstrak Buah Delima (Punica Granatum L.) Usman, Wilda Fhitriany; Widianti, Reika Aqni; Shaleh, Aries Badrus
Jurnal Farmasi & Sains Indonesia Vol 7 No 1 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no1p240-247

Abstract

Pomegranate is one of the fruits mentioned by Allah in the Koran and has many health benefits. In the Qur'an, Allah calls it al-rumman or what we usually call pomegranate. Red pomegranate (Punica granatum L.) contains flavonoids and phenols which are thought to be effective as antibacterials. The ointment is a semi-solid preparation that is easy to apply and is used as an external medicine, has direct access to the tissue and has greater aesthetic value. In this study, ointment preparations were formulated with variations of red pomegranate extract (Punica granatum L.) and propylene glycol in 7 ointment formulas. The evaluation tests carried out were organoleptic tests, spreadability tests, adhesiveness tests, pH tests, viscosity tests, stability tests and hedonic tests. The optimum preparation uses Simplex Lattice Design (SLD). The results of the physical evaluation of 7 formulas for various ointment preparations of pomegranate extract weighing 100 grams using PEG 400 and PEG 4000 bases and also the comparison of Propylene Glycol showed that 1 optimum formula was close to the recommended concentration based on the results of analysis using SLD, namely formulas 1 & 7 with concentration of pomegranate extract 5% and Propylene glycol 2% with 3 replications of the test. The evaluation results obtained were a semi-solid ointment evaluation test, typical rose smell, homogeneous, pH value 5.22, adhesion test 6.57 seconds, spreadability test 2.8 & 2.5 cm, viscosity test 3612 & 3611
Evaluasi Pengelolaan Obat pada Tahap Perencanaan, Pengadaan, Penyimpanan dan Pendistribusian di Puskesmas X Kampar, Riau Pratiwi, Denia; Adetian, Vini
Jurnal Farmasi & Sains Indonesia Vol 7 No 2 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no2p212-217

Abstract

The importance of a series of drug management in a health care system cannot be ignored, because if it is not done efficiently, it will have a negative impact on the health centre both in medical, social and economic terms. This study was conducted to determine the suitability of drug management related to the processes of planning, procurement, storage and distribution of drugs at the Puskesmas X Kampar with the Pharmaceutical Service Standards (PSS) 2019. This study uses a type of qualitative research using interview techniques, observation and completion of checklist sheets. The data from the checklist sheet, observation sheet and interview guidelines were processed and analysed using the content analysis method. The results showed that Puskesmas X Kampar in planning was not in accordance with the Pharmaceutical Service Standards (PSS) 2019, in drug procurement and distribution Puskesmas X Kampar was in accordance with the PSS at Puskesmas. For storage, there were still some that were not in accordance with the PSS 2019 such as not having pallets, high alert drugs were not specially marked, flammable materials such as pharmaceutical preparations and consumable medical materials (CMM) were not stored in a separate place from other drugs and the refrigerator was in a damaged.
HUBUNGAN POLIFARMASI DAN TEMUAN POTENSI INTERAKSI OBAT PADA PERESEPAN PASIEN ANAK DI APOTEK BUKIT SARI SEMARANG TAHUN 2021 Dariyati, Nita; Suwarni, Sri; Pitarisa, Agustina Putri; Serang, Yithro; Leki, Karol Giovani Battista
Jurnal Farmasi & Sains Indonesia Vol 5 No 2 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no2p14-19

Abstract

Polypharmacy is still frequent and very common in pediatric prescribing. Polypharmacy can increase the potential for drug interactions. Most of which have a detrimental impact on patient therapy. Drug interactions are considered clinically important when they result in increased toxicity or reduced therapeutic effectiveness. This study aims to determine the relationship between polypharmacy and the potential for drug interactions in the prescription of pediatric patients at Bukit Sari Pharmacy Semarang for the 2021 period. This research is a type of quantitative descriptive analysis research. Research data were obtained retrospectively in the period January - December 2021 which is based on the prescription data of pediatric patients at Bukit Sari Pharmacy Semarang for the 2021 period. The sampling technique used proportional random sampling method where samples were taken from pediatric patient prescriptions that met the inclusion criteria. Of the 270 prescription sheets analyzed, 160 prescription sheets experienced polypharmacy. Percentage of drug interaction events drug interaction was 36.7%. Statistical analysis using the Spearmans Test obtained a p value
PROMOSI KESEHATAN DENGAN METODE BEHAVIORAL CHANGE PADA ANGKA TEMUAN PASIEN SKABIES DI SEMUA CABANG KLINIK DERMA JAWA TENGAH Ernada, Nindya Widyani; Suwarni, Sri; Indrasari, Ferika; Leki, Karol Giovani Battista; Kusumaningtyas, Aprilia
Jurnal Farmasi & Sains Indonesia Vol 5 No 2 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no2p48-56

Abstract

Clinics as health care facilities also play a role in promotive and preventive. Scabies is an infectious skin disease caused by Sarcoptes scabei variant hominis which can be transmitted through direct human contact. This study aims to determine the effect of knowledge level and public health status to change patient behavior to live clean and healthy with behavioral change analysis of scabies rates in all branches of Kinik Derma Central Java. This type of research is observational with cross sectional design, purposive sampling technique. The population is all patients who come to the Derma clinic with a diagnosis of scabies in the January-April 2021 period. This research instrument uses a questionnaire sheet with the application of behavioral change measurement indicators, while for the diagnosis of scabies using the results of medical examination records. Data presentation is presented in the form of Histograms and percentages. The average knowledge of people with scabies answering about scabies disease is 78.02% answering correctly and for the average healthy and clean behavior (personal hygine) is 70.20%. Providing health promotion for the application of behavioral change methods used health promotion by providing brochures and IEC (Information Communication and Education) at the time of drug collection. When waiting for the medicine, it is also expected to see video shows on the Derma Clinic television screen. After a period of 2 months from the initial findings, the number of patients with scabies in all branches of Derma Clinic Central Java decreased by 24 patients or 20% of the number of patients at the beginning of the study.
IMPLEMENTASI MANAJEMEN RISIKO DI INSTALASI FARMASI RUMAH SAKIT UMUM DAERAH DR. R. SOEDJATI SOEMODIARDJO PURWODADI GROBOGAN Toyo, Eleonora Maryeta; Maryana, Mega; Suwarni, Sri; Rustaman, Heri; Susilawati, Linda
Jurnal Farmasi & Sains Indonesia Vol 5 No 2 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no2p57-68

Abstract

Risk is a state of uncertainty and can be measured quantitatively. Every service activity in the Pharmacy Installation contains risk. Risk management is a process of identifying, measuring, analyzing, and handling risks that may arise during service delivery. The implementation of risk management is expected to reduce and or eliminate losses incurred for the continuity of health services. This study aims to determine the implementation of risk management in the Pharmacy Installation of the Regional General Hospital Dr. R. Soedjati Soemodiardjo Purwodadi Grobogan. This research is a non-experimental research with descriptive method, namely retrospective data collection with total sampling technique. Samples were taken from the Quality Control Agency at the Regional General Hospital Dr. R. Soedjati Soemodiardjo Purwodadi Grobogan in the January-December 2020 period. The data obtained were tabulated, presented, and reported in percentage form for further qualitative and quantitative analysis. From the research results obtained, it is known that the most common type of incident is KPC in the prescription service category. This is influenced by factors including human resources, infrastructure, standard operating procedures, and formularies. The implementation of Risk Management in the Pharmacy Installation of the Regional General Hospital Dr. R. Soedjati Soemodiardjo Purwodadi Grobogan is still not effective, because it still experiences obstacles in several stages of the Risk Management process.
ANALISIS KEBUTUHAN TENAGA TEKNIS KEFARMASIAN BERDASARKAN BEBAN KERJA PADA PELAYANAN RESEP DI INSTALASI FARMASI RAWAT JALAN RS ROEMANI MUHAMMADIYAH SEMARANG Darsono, Dwi Aryaningtyas; Suwarni, Sri; Indrasari, Ferika; Rosita, Dian; Roslianti, Rini
Jurnal Farmasi & Sains Indonesia Vol 5 No 2 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no2p69-76

Abstract

One indicator of the success of an effective and efficient hospital is the availability of a sufficient number of human resources (HR) with high quality and professionalism in accordance with the functions and duties of each personnel. The Hospital Pharmacy Installation is a unit that plays a major role in supporting hospital operations. The purpose of the study was to determine the ratio of pharmaceutical technical personnel needs based on WISN analysis in the outpatient pharmaceutical installation of Roemani Muhammadiyah Hospital Semarang. This research is included in the type of descriptive qualitative research whose data management uses descriptive quantitative research studies. The method used workload indicators of staffing need (WISN) this method is accurately used to calculate the needs of human resources (HR) based on the real workload. The results showed that the need for pharmaceutical technical personnel at Roemani Muhammadiyah Hospital Semarang was 25 people, the comparison of reality and needs (ratio) of pharmaceutical technical personnel was 0.9, which showed that the number of pharmaceutical technical personnel was not in accordance with the existing workload. Factors underlying the need for pharmaceutical technical personnel in the outpatient installation include many prescriptions that accumulate in crowded hours, the work system is not yet appropriate, the pharmacy layout is not effective efficient, and the number of prescriptions served is not proportional to the current number of pharmaceutical technical personnel.
HUBUNGAN RASIONALITAS PENGGUNAAN ANTIBIOTIK DENGAN TINGKAT PENGETAHUAN PADA MASYARAKAT SEMARANG UTARA Wijianto, Deshinta Putri; Suwarni, Sri; Indrasari, Ferika; Ristita, Cinthya Nisha; Santoso, Arifin
Jurnal Farmasi & Sains Indonesia Vol 5 No 2 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no2p77-87

Abstract

Antibiotics have side effects of resistance if not used appropriately and rationally, Antibiotic resistance occurs because antibiotics lack the ability to control or kill microbial growth. Thus, to prevent the occurrence of antibiotic resistance must be taken appropriately. Knowledge in the correct use of antibiotics is an important role in the success of treatment process. The correct level of knowledge about antibiotics will affect the rationality in using antibiotics. The purpose of the study was to determine the relationship between the level of public knowledge on the rationality of antibiotics in North Semarang Community. This research was conducted with survey research method prospective survey research method with the population in this study is the community in North Semarang Subdistrict which amounted to 125,352 people, a sample of 405 was taken by purposive random sampling, by purposive random sampling. The data obtained were analyzed using the Spearman correlation test statistical test. Results of community knowledge level in North Semarang Sub-district North Semarang Subdistrict as a whole was categorized as “moderate” as many as 191 respondents (47.2%). respondents (47.2%). People in North Semarang Sub-district as a whole used antibiotics rationally as many as 211 respondents (52.1%). The level of knowledge influenced the rational use of antibiotics in North Semarang District (0.000 < 0.050) there is a significant correlation between the two variables. variables that are connected. The correlation coefficient value is 0.614 the strength of the correlation obtained is included in the strong category. There is a relationship between knowledge level on the rationality of antibiotic use in the community of North Semarang District.
KEPATUHAN PELAPORAN TEMUAN MEDICATION ERROR OLEH TENAGA KEFARMASIAN PADA IMPLEMENTASI BUDAYA PATIENT SAFETY DI LIMA PUSKESMAS KOTA SEMARANG Dewi, Adinta Citra; Suwarni, Sri; Indrasari, Ferika; Roslianti, Rini; Septiyana, Ria
Jurnal Farmasi & Sains Indonesia Vol 5 No 2 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no2p88-96

Abstract

Patient safety is a new discipline in health care that prioritizes the reporting, analysis, and prevention of medical errors that often lead to adverse events in health care. Prescription screening activities carried out by pharmaceutical personnel to prevent the occurrence of medication errors (Medication error) the purpose of the study was to determine the implementation of reporting the findings of medication error in prescription services on Patient Safety Culture reporting at five Primary Healthcare in Semarang City. This study is a non-experimental study, this study uses observational methods with quantitative data. Data collection with structured observation sheet instruments using the parameters of the Indonesian Minister of Health Regulation No. 11 of 2017 concerning Patient safety, the population of this study was the Patient Safety Team in five Primary Healthcare in Semarang city, namely 24 officers with total sampling technique. Analyze the results with a percentage range classification to determine the level of implementation. Compliance with reporting incident findings / medication errors as a form of implementation of patient safety culture in five Primary Healthcare in Semarang City has a high compliance value of 84.81% from the perspective of pharmaceutical personnel and is included in the high category.
KEPUASAN PASIEN PADA PEMBERIAN PIO PENJUALAN SWAMEDIKASI TERHADAP CUSTOMER LOYALTY DI APOTEK SYARINA KABUPATEN SEMARANG Fitriani, Sefia; Suwarni, Sri; Wulandar, Ratna; Rustaman, Heri; Kusumaningtyas, Aprilia
Jurnal Farmasi & Sains Indonesia Vol 6 No 1 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no1p144-153

Abstract

Pharmaceutical services are currently developing along with increasing public awareness of the importance of health. A pharmacy is a means for carrying out pharmaceutical work and a means for serving pharmaceutical supplies to the community. One of the pharmaceutical jobs carried out in pharmacies is Drug Information Services. The purpose of this study was to analyze the relationship between patient satisfaction in giving drugs informations for self-medication sales to customer loyalty at the Syarina Pharmacy, Semarang Regency. This research is a quantitative research using survey method. Data was collected by purposive sampling method and using the Slovin formula to determine the sample size and population. The research subjects were all customers who received drug information services on self-medication at the Syarina Pharmacy, Semarang Regency using the Pearson correlation analysis method. The results of the analysis show that there is a relationship between the level of patient satisfaction and customer loyalty at the Syarina Pharmacy with siq = 0.00

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