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Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 2502647X     EISSN : 25031902     DOI : https://doi.org/10.36387/jiis
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 429 Documents
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SOSIOEKONOMI, PENGETAHUAN PENYAKIT DIARE DAN PENGETAHUAN SWAMEDIKASI DIARE PADA IBU BALITA DI YOGYAKARTA Faridah Baroroh; Ana Hidayati; Siti Nurbayanti; Intan Tin Sari; Atikah Zain; Redy Redy; Siwi Retnaning Dyahayu
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.047 KB) | DOI: 10.36387/jiis.v6i2.715

Abstract

In Indonesia, the prevalence of diarrhea is highest among children under five. Economic factors and maternal knowledge are, in this case, significantly related to diarrhea incidence, and the latter substantially defines self-medication measures taken for acute diarrhea treatment. The research was intended to determine the extent to which socioeconomic conditions and diarrheal knowledge formed comprehension of such treatment. For this purpose, it employed a cross-sectional study with 504 research subjects, namely, mothers of children under five in the Special Region of Yogyakarta, Indonesia. Data were collected using a validated questionnaire consisting of items on socioeconomic details (education, employment, income), diarrheal knowledge, and relevant self-medication knowledge. Afterward, education and post-test were conducted using the same list of questions. Analytical techniques were carried out to identify how significant socioeconomic characteristics determined knowledge of diarrheal disease and self-medication.Results showed that, socioeconomically, a large proportion of research subjects attained secondary to tertiary education (76%), were unemployed (71%), and earned low income (62%). Educational attainment was found to be significantly related to levels of knowledge of diarrheal disease and self-medication (p < 0.005), but employment status and income were not (p > 0.005). Analysis results also indicate a significant relationship (p = 0.000) between the level of knowledge of diarrheal disease and that of diarrheal self-medication. Overall, socioeconomic status (i.e., level of education) and diarrheal knowledge is significantly related to diarrheal self-medication knowledge.
POTENSI DARI EKSTRAK DAN FRAKSI KULIT BUAH MUNDAR (Garcinia forbesii) SEBAGAI TABIR SURYA BERDASARKAN NILAI SUN PROTECTION FACTOR (SPF) Muhammad Ikhwan Rizki; Samsul Hadi; Lutfi Chabib
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (201.827 KB) | DOI: 10.36387/jiis.v6i2.716

Abstract

UV rays cause skin damage such as loss of skin elasticity, wrinkles, sagging, and skin cancer. South Kalimantan is a wetland area with more than 4,000 species of medicinal plants. Mundar (Garcinia forbesii) is one of the plants in South Kalimantan. Mundar pericarp is empirically used for cosmetics which is believed to protect the skin from ultraviolet rays. The purpose of the study was to determine the sunscreen potency of the extract and fraction from pericarp of mundar (Garcinia forbesii) based on the Sun Protection Factor (SPF) parameter. The research started from material drying, making simplicia powder, extraction, and fractions. The extracts and fractions were measured for SPF values ??using a UV-Vis Spectrophotometer. The results showed that the ethanol extract and ethyl acetate fraction had weak protection, while the n-hexane fraction had extreme protective power with SPF values ??in the range of 6.51 – 30.00
ANALISIS EFEKTIVITAS BIAYA PENGGUNAAN AMLODIPIN DIBANDINGKAN KAPTOPRIL PADA PASIEN HIPERTENSI DI RUMAH SAKIT UMUM DAERAH MAJENE PERIODE JANUARI HINGGA JUNI TAHUN 2019 Andi Maulana Kamri; Rachmat Kosman; Dian Rahayu
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (189.941 KB) | DOI: 10.36387/jiis.v6i2.718

Abstract

Hypertension is a chronic disease that requires long-term treatment and high cost. The research aimed to determine a more cost-effective treatment between amlodipine and captopril in hypertensive patients at Majene Hospital from January to June 2019. The sampling technique was purposive sampling with a cross-sectional method. The data collection was obtained from medical records and direct medical costs of hypertensive patients who take amlodipine or captopril. The Mann-Whitney statistical test was performed to determine the significant difference between the treatment groups. The results showed that the Average Cost Effectiveness Rasio (ACER) value of the 5 mg amlodipine and 12.5 mg captopril groups was Rp. 4233.3 and Rp. 4904 with an Incremental Cost Effectiveness rasio (ICER) value of Rp. 1063.5. Meanwhile, the Average Cost Effectiveness Rasio (ACER) value of the 10 mg amlodipine and 25 mg captopril group was Rp. 3764,7 and Rp. 4875.1. In conclusion, amlodipine is more cost effective than captopril.
UJI TOKSISITAS AKUT EKSTRAK ETANOL DAUN KAYU MANIS (Cinnamomum burmanii) PADA FUNGSI HATI TIKUS PUTIH (Mus musculus L.) BETINA Yesi Nursofia; Fathnur Sani K; Yuliawati Yuliawati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (190.481 KB) | DOI: 10.36387/jiis.v6i2.720

Abstract

Cinnamon leaves (Cinnamomum burmanii) are plants that have many pharmacological effects including lowering blood sugar levels, inhibition of bacterial growth, antioxidants and mymetic insulin activity. However, acute toxicity testing has not been carried out on cinnamon leaves before. This study aims to determine the level of toxicity and effect of extract administration on SGOT, SGPT as well as changes in the histopathological form of the liver of test animals. This study used The Complete Randomized Design method with 5 treatment groups with na-CMC administration 0.5% as a negative control, P1 dose 250 mg/kgBB, P2 Dose 500 mg/kgBB, P3 dose 1000 mg/kgBB and P4 at a dose of 2000 mg/kgBB. Each treatment consists of 5 mice. The parameters observed in this study are SGPT, SGOT and histopathological examination of mice liver organs. The data was analyzed using the One Way ANOVA test with duncan's advanced test. The results showed that the administration of cinnamon leaf ethanol extract did not cause death in test animals so it was practically not toxic. SGPT and SGOT values in female white mice test animals showed statistically meaningful differences in SGPT and SGOT values (p<0.05) compared to negative controls. However, it is still in the normal range. The result of histopathological observations is that there is a change in hepatocytes of liver organs compared to negative control.
FORMULASI, KARAKTERISASI DAN UJI STABILITAS MIKROEMULSI MINYAK NILAM (Pogostemon cablin Benth.) Benni Iskandar; Anita Lukman; Raesa Tartilla; Meircurius Dwi Condro Surboyo; Leny Leny
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (168.629 KB) | DOI: 10.36387/jiis.v6i2.724

Abstract

Patchouli oil contains patchouli alcohol as the main component which is a tricyclic tertiary alcohol sesquiterpene compound that is insoluble in water. Microemulsion is a droplet dispersion technology that combines an insoluble liquid with another liquid. The role of surfactants in helping the dispersion process of microemulsion formulation is by reducing the interfacial tension. Microemulsion is a supersolvents carrier, so that both hydrophilic and lipophilic can be administered through a microemulsion system. The purpose of this study was to formulate patchouli oil into a stable microemulsion preparation. This research was conducted by making 4 preparations of patchouli oil microemulsion containing 5% (F1), 10% (F2), and 15% (F3) patchouli oil, and microemulsion without patchouli oil (F0). Evaluation of microemulsion preparations includes organoleptic test, pH measurement, density determination, viscosity test, freeze and thaw test, centrifugation test, and particle size analysis. The test results showed that the microemulsion containing 5% patchouli oil had the most stable characteristics compared to other formulas.
HUBUNGAN PENGETAHUAN TERHADAP PERILAKU PENGGUNAAN SUPLEMEN DAN OBAT HERBAL DALAM MENCEGAH PENULARAN COVID-19 DI BANJARBARU SELATAN Esty Restiana Rusida; Syahrizal Ramadhani; Depy Oktapian Akbar
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (212.937 KB) | DOI: 10.36387/jiis.v6i2.728

Abstract

Indonesia is one of the highest confirmed countries in ASEAN and South Kalimantan is still in the 13th order category in Covid-19 cases. One of the measures to prevent its spread is to increase the immune system by consuming health supplements or herbal medicines. Knowledge influences in shaping one's behavior. The purpose of this study was to determine the relationship between knowledge and behavior in the use of supplements and herbal medicines in preventing the spread of Covid-19 in South Banjarbaru. This research is descriptive analytic with a cross sectional design, data collection by proportional random sampling technique with an instrument in the form of google form with a sample of 398 respondents. The data analysis used is univariate and bivariate using chi square. The conclusion shows that the level of public knowledge about supplements and herbal medicines in the South Banjarbaru sub-district is mostly knowledgeable enough by 43.5% with the majority of the behavior of using supplements and herbal medicines being inappropriate at 68.3%. The results of the chi square statistical test showed that there was a relationship between knowledge and behavior in the use of supplements and herbal medicines with a value of 0.000 (sig. <0.05).
PENGARUH METODE PENGERINGAN TERHADAP KADAR SENYAWA BIOAKTIF DAN AKTIVITAS ANTIOKSIDAN PADA HERBA SURUHAN (Peperomia pellucida L.) Dewi Puspita Apsari; Muhammad Nanda Aprilianto; Ni Luh Desyani; Ni Putu Widayanti
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (195.658 KB) | DOI: 10.36387/jiis.v6i2.731

Abstract

Suruhan herb have been used globally as concoction for medical and therapeutic purposes, so that it is much needed to investigate their phytonutrients. The variations in drying methods can affect the levels of bioactive compounds and antioxidant activity, so an appropriate drying strategy is needed to produce simplicia that containing high bioactive compounds and antioxidant activity. Based on the considerations above, this study aimed to determine the effect of various drying methods strategies (direct sunlight, oven drying and wind drying) on the bioactive compounds and antioxidant activity of the suruhan herb. The extract of suruhan herb were subsequently analyzed for total flavonoids, total phenols, total tannins, and their antioxidant activity. The results showed that oven-dried suruhan herb produced the highest potential antioxidant activity, that was 94.67 ppm with total flavonoids 51.00 mgQE/g extract, total phenol 63.36 mgGAE/g extract, and total tannins 41.89 mgTAE/g extract. It can be concluded that the variety of drying strategy has a significant impact (p<0.05) on the bioactive content and antioxidant activity of the suruhan herb.
PENGARUH EDUKASI MEDIA BOOKLET TERHADAP PENGETAHUAN DAN SIKAP ORANG TUA TENTANG IMUNISASI DASAR PADA MASA PANDEMI COVID-19 Eny Hastuti Hastuti; Sari Wahyunita; Aesty Rahayu; Wahyudi Wahyudi
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (460.168 KB) | DOI: 10.36387/jiis.v6i2.736

Abstract

The Indonesian government is taking several steps to ensure the control of COVID-19 and strengthen the capacity of the health care system to handle the pandemic period. One of them is the coverage of basic immunization to prevent diseases in children such as measles, rubella, and diphtheria which is decreasing, including the number of immunization coverage for diphtheria, pertussis, tetanus (DPT3) and measles and rubella (MR1) has decreased by more than 35%. Immunization services are reopened to prevent Extraordinary Events (KLB) of diseases in children that can be prevented by immunization (PD3I), to socialize a series of guidelines, standard operating procedures (SOP), as well as communication, information, and education (KIE). This study aims to determine the effect of booklet media education on parents' knowledge and attitudes towards basic immunization during the COVID-19 pandemic. Research Design Nonrandomized pre-test post-test with control group design. The total sample of 158 respondents was divided into 2 groups, the intervention group which was educated with booklet media and the control group without booklet education. The results showed that booklet media education was very influential (p = 0.001) on parents' knowledge and attitudes about basic immunization during the COVID-19 pandemic, this proves that booklet media is a communication tool that can be used by health workers to help increase parents' knowledge so as not to worry about bringing children to health services to keep immunizing during this COVID-19 pandemic.
UJI AKTIVITAS TABIR SURYA DAN ANTIOKSIDAN EKSTRAK ETANOL DAUN SUNGKAI (Perenema canescens Jack) Fadlilaturrahmah Fadlilaturrahmah; Amalia Khairunnisa; Aditya MP Putra; Ivanna Sinta
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (436.265 KB) | DOI: 10.36387/jiis.v6i2.737

Abstract

Indonesia, which is located in the tropics, causes people's skin to easily experience premature aging and tan. Most of these cosmetic products contain dangerous synthetic chemicals. For this reason, cosmetic products with natural active ingredients or phytocosmetics that are effective and safe to use need to be developed. One of the typical natural plant plants from South Kalimantan that has the potential to be developed as a cosmetic preparation is Sungkai (Peronema canescens Jack). The aim of the study was to determine the antioxidant activity and sunscreen activity of Sungkai leaves. The method used for the determination of antioxidant activity is the DPPH method using a uv-vis spectrophotometer and for the determination of sunscreen activity using a uv-vis spectrophotometer. The results showed that the P. canescens plant extract contained anthraquinones, flavonoids, saponins, tannins, and phenols. P.canescens plants have an Inhibitory Concentration 50 (IC50 ) of 42.219±19.440 ppm and have sunscreen activity with spf (Sun Protecting Factor) values ??with concentrations of 600 ppm, 400 ppm, 200 respectively as follows: 24±0.31; 16±0.34; and 8±0.3. The conclusion of this study Sungkai (Peronema canescens Jack) has antioxidant activity and has sunscreen activity so that it has the potential to be developed into natural skin care.
ANALISIS HUBUNGAN KEPATUHAN PENGOBATAN TERHADAP KONTROL GLIKEMIK PASIEN DIABETES MELITUS TIPE 2 DI INSTALASI RAWAT JALAN RUMAH SAKIT “X” BULELENG Pande Made Desy Ratnasari; I Gusti Ayu Indira Ardeliani; Agustina Nila Yuliawati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (406.684 KB) | DOI: 10.36387/jiis.v6i2.739

Abstract

Type 2 Diabetes mellitus (T2DM) is a chronic disease that requires long-term treatment. There were problems related to antidiabetic medication adherence. Medication adherence directly affects patient’s blood glucose level. The aim of this study was to analyze the association between the medication adherence and glycemic control among T2DM patients. The study was an observational with cross sectional design. Participants were 90 of T2DM outpatient at “X” Buleleng General Hospital in July-September 2020. T2DM patients were included if age ?18 years, received the same antidiabetic for three months before the study, sign informed consent, fill out the questionnare and have fully medical record data. Patient are excluded if having weak general condition, were pregnant or breastfeeding. Data was collected through interview using the Probabilistic Medication Adherence Scale (ProMAS) questionnaire and based on patient’s medical records. Data were analyzed with Kruskall-Wallis test. The results showed that most of patients were male (55.6%), aged 46-65 years (61.1%), had DM for 5-10 years (46.7%), elementary school (37.8%), with comordbidities (50%) and without complications (77.8%). Majority of patients (42.2%) showed moderate-high medication adherence and the majority of patients (66.7%) has uncontrolled blood glucose. Based on statistical tests, there was no association between medication adherence with patient’s glycemic control (p=0.168). In dispite of it, finding showed that the level of medication adherence had an impact on glycemic control. Patients with high medication adherence showed better glycemic control.

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