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Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan

JIIS
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Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

ISSN : 2502647X EISSN : 25031902 DOI : https://doi.org/10.36387/jiis

Core Subject : Health,

Medicine & Pharmacology

Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi

Articles 429 Documents

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AKTIVITAS FRAKSI ETIL ASETAT KULIT BUAH JERUK NIPIS (Citrus aurantifolia (Christ) Swing) SEBAGAI ANTIPIRETIK PADA MENCIT YANG DIINDUKSI VAKSIN DPT Satrio Wibowo Rahmatullah; Eka Fitri Susiani; Muhammad Reza Fahlevi; Guntur Kurniawan; Siti Nurhaliza Leyla
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Lime (Citrus aurantifolia (Christm.) Swing) is one of the types of oranges containing elements of compounds that are beneficial, so widely used as traditional medicine. This research aims to know the antipyretic activity of ethyl acetate fraction peel of lime. Phytochemical screening test result fraction ethyl acetate lemon rind contains flavonoids, saponins, alkaloids and essential oils. Total of 25 mice were divided into 5 groups, group I negative control, group II positive control, group III,IV,V were given ethyl acetate fraction at a dose of 0,07%/gBW,, 0,105%/gBWand 0,14%/gBW. Based on the results of graph average temperatures decrease the dose that the third has antipyretic activity because it can lower the temperature and the largest decreased in temperature at a dose 0,14%/gBW. Based on the test result ANOVA obtained sig. value 0,000. which means there is a temperature difference of meaning between 5 group treatment. And on Independent Test Sample T-test between a positive control with a dose 0,14%/gBW the value of sig. 0,601 (> 0,05) which means there is no meaningful difference.

ISOLASI DAN IDENTIFIKASI SENYAWA FLAVONOID FRAKSI ETIL ASETAT EKSTRAK DAUN AFRIKA (Vernonia amygdalina Del.) Ni Ketut Esati; I Putu Eka Budiarta; Kadek Duwi Cahyadi; Gusti Ayu Dewi Lestari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

African leaves (Vernonia amygdalina Del.) are reported to have activity as anti-malarial, antibacterial, anticancer, antioxidant, and others. This is closely related to the secondary metabolite compounds, that are contained in african leaves. One of the secondary metabolites that have a big role in the efficacy of african leaves is flavonoids. So that the purpose of this study, to isolated and identified the flavonoid compounds from african leaves. The plants were picked directly in the Tabanan area, Bali. The stages of this study were making the ethanol extract of african leaves, skrinning of the secondary metabolite compounds from the ethanol extract of african leaves. After that, the isolation and purification of flavonoids in ethyl acetate fraction from extract of african leaves are doing. Then the isolate of flavonoid compounds are identified using Ultra Violet-Visible (UV-Vis) and Infrared (IR) spectrophotometer methods. From the results of this study, the yield of ethanol extract was 3.693% derived from maceration of African leaf simplicia powder using 96% ethanol as solvent. The results of phytochemical screening, African leaf ethanol extract contains alkaloids, flavonoids, phenolic compounds, steroids, and saponins. The results of the fractionation obtained n-hexane fraction as much as 2.57 grams, ethyl acetate fraction 0.53 grams, and water fraction as much as 3.02 grams. The flavonoid compounds in the ethyl acetate fraction were separated and isolated, resulting in 2 isolates which were further identified by UV-Vis and IR spectrophotometry. The results obtained with the addition of shear reagents that the ethyl acetate fraction contains flavonoids of the flavone group (7-hydroxyl free), and on examination by IR spectrophotometry showed the presence of OH groups, aliphatic CH, C=O, aromatic C=C, CO alcohol, and aromatic CH.

FORMULASI SEDIAAN GEL PEEL-OFF EKSTRAK BUAH LIMPASU (Baccaurea lanceolate (Miq) Mull.Arg.) SEBAGAI ANTIBAKTERI Deni Setiawan; Nur Mahdi; Muhammad Riki Shindi Praristiya
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Skin is a protective layer of the body as well as an aesthetic factor to protect from exposure foreign substances and sunlight. Some problems that may arise on the skin include premature aging and acne. The use of natural ingredients as cosmetics is increasing, one of which is the limpasu fruit peel-off gel mask. This study aims to determine the antibacterial activity of the ethanol extract of limpasu fruit extract. The formulation was made with three concentrations of ethanol extract of limpasu fruit (Baccaurea lanceolate) 4, 6 and 8 grams. The formula was tested on E.coli. The yield of limpasu fruit extract was 30.49 grams or 7.81%. Results of preliminary identification of ethanol extract containing saponins and flavonoids. The results of the antibacterial test formulas 1 to 3 had inhibition zones 12, 53; 7.94 and 9.97 mm with a positive control of tetracycline which had an average inhibition zone of 28.87 mm. The peel-off gel formulation had antibacterial activity because the average inhibition zone was more than 6 mm.

STUDI ETNOMEDISIN PADA MASYARAKAT 5 DESA KECAMATAN SECANG KABUPATEN MAGELANG Alfian Syarifuddin; Rizka Amalia
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

The use of plants for traditional medicines are community tradition in Indonesia. However, the use of plants for hereditary treatment has not been well documented. One of the solutions is an ethnomedicine study, in this study 5 villages located in Secang District, Magelang Regency. The sampling technique used is snowball sampling with observation using instruments and interviews. The number of respondents sample is 388 respondents. The results showed that the community utilized 96 plant species from 47 families. There are 3 types of diseases that use plants in their treatment with an ICF value of 1, namely sprains, nosebleeds, and menstrual flow. The most widely used parts for treatment are leaves (42.61%). The most frequently used processing method is the boiling technique with a percentage of 65.10% by way of use, which is drinking 77.05%. People most often consume with a frequency of 2x a day (74.87%). People usually use treatment during illness/ curative (76.74%). People get plants from their own yard (54.24%). Knowledge about treatment comes from family (hereditary) (72.43%). From some of the results, it can be used as a reference when conducting scientific verification of preclinical testing on test animals.

FORMULASI DAN UJI AKTIVITAS SABUN CAIR ANTISEPTIK DARI EKSTRAK KULIT BUAH KAPUL (Baccaurea macrocarpa) Nur Mahdi; Farhandika Putra; Nuraini Manurung
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Kapul fruit is a typical plant of Kalimantan known by the Latin name Baccaurea macrocarpa. The rind of Baccaurea macrocarpa has antibacterial potential, so it is necessary to develop it into liquid soap preparations. The purpose of this study was to formulate and test the antiseptic activity of liquid soap from the extract of Baccaurea macrocarpa rind. Kapul fruit peel extract was divided into 4 different concentrations (F0 0%, FI 1%, FII 2%, and FIII 3%) formulated in liquid soap preparations. The evaluation of liquid soap includes physical characteristics (organoleptic, homogeneity, dispersion test), pH, and antibacterial test. The results of the organoleptic test, dispersive test, pH, antibacterial test Kapul fruit rind extract showed no significant difference in the pH, dispersibility, and antibacterial test. Based on the results of the evaluation of the preparations, all formulas showed good characteristics. The formula I has a good antibacterial effect.

PENGUKURAN FAKTOR RISIKO KETIDAKPATUHAN PENGOBATAN TUBERCULOSIS KHUSUSNYA HEALTH SYSTEM PADA PASIEN PINDAHAN Leonov Rianto; Siti Aisyah; Ika Agustina
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

During the Covid-19 pandemic, there was a transfer of TB patient referrals from other health facilities to The X Hospital which took effect in April 2020. One of the five factors that caused non-compliance with treatment was the health system. The sub factor included in this is Health facility. The transfer of patient referrals is predicted to be associated with the success rate of TB treatment. This study aims to describe the health system risk factors for non-adherence to treatment of drug-resistant TB (RO) patients. This study uses a quantitative descriptive approach. The population in this study were RO TB patients. The sampling technique is total sampling. The inclusion criteria in this study were RO TB patients whose treatment period was > 6 months and there had been a transfer of health facilities to the Cempaka Putih Islamic Hospital. The total sample obtained is 35 respondents. The results showed that the health system risk factor for non-adherence to treatment of Drug Resistant TB (RO) patients was low because patients did not experience problems in terms of distance to health facilities and competent health workers in providing information about treatment for RO TB patients.

PENGARUH PENGGUNAAN TAS PENYIMPANAN OBAT TERHADAP KONTROL TEKANAN DARAH PASIEN HIPERTENSI Niken Larasati; Sugiyono Sugiyono
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Number of people with hypertension in Indonesia is increasing. In addition, not all patients diagnosed with hypertension are adherent to treatment. Based on the 2018 Basic Health Research data, Yogyakarta was ranked second as the province with the highest hypertension patients in Indonesia. The purpose of this study is to determine the effect of using a medicine storage bag on blood pressure control of hypertension patients. This study used a pretest and posttest design with a control group of 36 patientsÃ¢â‚¬â„¢ sample at the Puskesmas Gamping 1 Yogyakarta from March to August 2019. At the beginning of the study, blood pressure data of patients in both groups were taken. The intervention group was given counseling to patients with medicine storage bags. Observations were made on the results of therapy in the form of controlled blood pressure attainment. The intervention resulted in a p-value of 0.031 for systolic and 0,000 for diastolic (p-value <0.05) indicated that there was an effect of using a medicine storage bag on the control of systolic and diastolic blood pressure in hypertensive patients. This study might conclude that medication aids are useful for hypertensive patients because they can increase the achievement of therapeutic targets.

UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAN FRAKSI n-HEKSAN, ETIL ASETAT DAN AIR DARI SABUT KELAPA MUDA (Cocos nucifera Linn) TERHADAP Escherichia coli ESBL (Extended Spectrum Beta Lactamase) Novia Dewi Purwaningrum; Lusia Murtisiwi; Diah Pratimasari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Young coconut coir contains flavonoid compounds, phenols, tannins and saponins. The ethanol extract of young coconut coir was studied to have good antibacterial activity. This study aimed to see the inhibitory activity of ethanol extract compared fractions of young coconut coir ethanol extract in inhibiting Escherichia coli ESBL (Extended Spectrum Beta Lactamase) bacteria. Young coconut coir of extracted using 95% ethanol solvent of maceration method and patition using n-hexane and ethyl acetate solvent. Antibacterial activities using the diffusion method with concentrations of 25%, 50% and 75%. The negative control used DMSO 10%, while positve control used was chloramphenikol. Ethanol extract and fractions of ethanol extract of young coconut coir inhibited Escherichia coli ESBL bacteria. The largest radical inhibition zone was found in the ethyl acetate fraction with a concentration of 75% at 10.9 mm.

ANALISIS KADAR OKSALAT PADA DUA JENIS TANAMAN KALE (Brassica oleracea var. acephala dan Brassica oleracea var. palmifolia ) DENGAN METODE SPEKTROFOTOMETRI UV Emma Emawati; Deden Indradinata; Dina Yulia Agustina
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Vegetables have an important function for metabolic and physiological processes in the body. Kale is dubbed as a super food because it has great health benefits. Kale contains nutrients such as vitamins A, C, potassium, calcium, iron, and manganese. Although vegetables have a lot of nutritional content, they also contain anti-nutrients, one of which is oxalic acid. Oxalic acid can irritate the intestines and can be fatal if taken in high doses, so it should be limited to 0.60-1.25 g per day. The purpose of this study was to determine the levels of oxalate in kale by UV spectrophotometry method measured at a wavelength of 351 nm. The product of the reaction is I3 which is proportional to the oxalate concentration. This research begins with method validation. The results of the validation of the calibration curve analysis method have a regression line equation y = 0.4943x + 0.244 with a correlation coefficient 0.998. The detection limit and quantization limit are 0.4018 and 1.3395. The coefficient of variance is 0.8180 and the percent recovery is 89, 92 and 101%. The results of this study showed that the oxalate content in curly kale was 0.6911 mg/100g and kale nero was 1.7045 mg/100g.

UJI EFEKTIFITAS SEDIAAN SPRAY GEL EKSTRAK BUNGA KENOP (Gomphrena globosa L) TERHADAP PENYEMBUHAN LUKA BAKAR Irma Novrianti; Sari Wijayanti; Heriani Heriani
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

A burn wound is tissue damage after contacting a heat source. Globe amaranth (Gomphrena globosa) is effective for healing burn wounds. This research analyzes the formula of spray gel pursuant to pharmaceutical requirements and the spray gelÃ¢â‚¬â„¢s ability to heal burn wounds. The spray gel preparation was made from 12.5%, 15%, and 20% concentrations of globe amaranth extract. Based on the stability test, the spray gel of globe amaranth preparation is stable in storage The test of the effectiveness of globe amaranth-based gel spray for healing burn wounds was conducted on test animals divided into five groups, i.e., control positive (bioplasentonÃ‚Â®), control negative (gel-base), FI (spray gel preparation at a 12.5% concentration of globe amaranth extract), FII (spray gel preparation at a 15% concentration of globe amaranth extract), and FIII (spray gel preparation at a 20% concentration of globe amaranth extract) and induced using an iron plate of diameter 1.5 cm. The results indicated a burn wound healing percentage of 51.33% (P%) on test animals on day 14. On FII, the P% was 62%, and FIII, the P% was 63.33% at p < 0.05. The percentage of burn wound healing on FII and FIII was the same as that on control positive at p > 0.05. To conclude, the spray gel preparation from globe amaranth extracts at 15% and 20% concentrations was effective for healing burn wounds.

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Contact Name
Siska Musiam

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Jl. Flamboyan III/7c Kayu Tangi 70123 Banjarmasin Kalimantan Selatan

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Kalimantan selatan

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