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INDONESIA
Jurnal Farmanesia
Published by Universitas Sari Mutiara Indonesia
ISSN : """"     EISSN : 25282484     DOI : https://doi.org/10.51544/jf.v8i2
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmanesia dengan E-ISSN: 2528-2484 merupakan jurnal resmi yang diterbitkan oleh Program Studi S1 Farmasi Fakultas Farmasi dan Ilmu Kesehatan Universitas Sari Mutiara Indonesia, yang artikelnya dapat diakses dan diunduh secara online oleh publik (open access journal). Jurnal ini merupakan jurnal peer-review yang diterbitkan dua kali setahun dengan topik keunggulan hasil penelitian di bidang pelayanan dan praktik kefarmasian, teknologi farmasi, dan disiplin ilmu kesehatan yang berkaitan erat. Jurnal ini menerima teks bahasa Indonesia. Berikut ini adalah area penelitian yang menjadi fokus jurnal ini: 1. Farmakologi 2. Farmasetika 3. Biologi Farmasi 4. Kimia Farmasi 5. Farmakognosi 6. Fitokimia
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 248 Documents
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UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BIJI PINANG (Areca catechu L.) TERHADAP PERTUMBUHAN BAKTERI Escherichia coli, Shigella dysentriae, DAN Salmonella typhi Sitompul, Erly; Hafizullah, Ahmad; Silalahi, Yosy Cinthya Eriwaty; Telaumbanua, Realisni
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2705

Abstract

One of the medicinal plants is the areca nut (Areca catechu L.) from the Arecae family which has the potential as an anticancer having antioxidant and antimutagenic, astringent, and anthelmintic effects. Areca nut seeds contain alkaloids, such as arekoline, arekolidine, arekain, guvakolin, guvasine and isoguvasine. This study aims to determine the characteristics of the betel nut (Areca catechu L.) simplicia, class of compounds, and the antibacterial activity of the ethanol extract of areca nut (Areca catechu L.) against the growth of Escherichia coli, Shigella dysentriae, and Salmonella typhi bacteria. The method used is the ethanol extract of areca nut (Areca catechu L.) obtained from the maceration process with 96% ethanol. The results of phytochemical screening showed that the ethanolic extract of areca nut (Areca catechu L.) contains a group of alkaloid compounds, tannins, flavonoids, saponins, and triterpenoids. The effect of giving young betel nut ethanol extract to Escherichia coli, Shigella dysentriae, and Salmonella typhi bacteria was indicated by the formation of an inhibition zone of optimum concentration. The ethanol extract of old betel nut against Escherichia coli, Shigella dysentriae, and Salmonella typhi bacteria was characterized by the formation of an optimum concentration inhibition zone. Based on the results, it can be concluded that the ethanol extract of areca nut (Areca catechu L.) has antibacterial activity against Escherichia coli, Shigella dysentriae, and Salmonella typhi.
PENETAPAN KADAR KLORIN PADA BEBERAPA MERK PEMBALUT WANITA YANG ADA DI PASARAN DENGAN METODE IODOMETRI Daulay, Anny Sartika; Lubis, Minda Sari; Sandika, M Teguh
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2706

Abstract

Sanitary napkin is a device product used by women during menstruation, sanitary napkins function to absorb blood from the vagina so that the blood that comes out does not interfere. Currently, there are many problems that arise in sanitary napkins, due to the presence of chlorine additives which function as an ingredient in the initial bleaching process of sanitary napkins. The purpose of this study was to identify the color reaction test, and to determine the chlorine content by iodometry method in sanitary napkins on the market. This research is an experimental study using a sample of sanitary napkins on the market. Sampling by random sampling (random). Determination of chlorine in sanitary napkins by testing qualitatively with a color reaction and quantitatively using the iodometric method.Based on the results of the study, it was found that of the 5 (five) samples used, 3 (three) positive samples contained chlorine, namely samples A, B and sample C. The chlorine content obtained in sample A was 0.0035%, sample B was 0.0014 % and sample C is 0.0027%. According to YLKI, the normal threshold for the use of chlorine in sanitary napkins is 5-55 ppm, so the samples tested still meet the stipulated conditions.
PENGARUH MINYAK SAWIT MERAH (RPO) DAN MINYAK ZAITUN MURNI (EVOO) TERHADAP PERTUMBUHAN RAMBUT PADA KELINCI Sofwan, Ahmad Gazali; Hafizullah, Ahmad; Adiansyah, Adiansyah; Tampubolon, Rika Rosalinda
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2710

Abstract

Haircare products are very important to prevent one of the problems of hair damage, both from synthetic and natural ingredients. One of the natural ingredients of hair care products is Red Palm Oil (RPO) and Extra Virgin Olive Oil (EVOO). This research is an experimental study that aims to see whether Red Palm Oil and Extra Virgin Olive Oil have effectiveness in growing hair. This research method used 4 groups of test animals, namely the red palm oil group, extra virgin olive oil, negative control (aqua dest), and positive control (minoxidil). The hair growth activity test was carried out by applying each formula to the marked rabbit's back and measuring the length of the hair using a caliper on the 5th, 10th, 15th, 20th, 25th, and 30th days. On the 31st day, the hair weight was tested by weighing the hair using an analytical balance. The results showed that each formula had hair growth activity, but the most effective oil preparation in accelerating hair growth was Red Palm Oil (RPO).
PENENTUAN KONSENTRASI HAMBAT MINIMUM (KHM) DARI EKSTRAK BUAH SAWO TERHADAP Salmonella typhi Nurbaya, Siti; Silalahi, Yosy Cinthya Eriwaty; Nurussakinah, Nurussakinah; Purba, Trionaldo
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2713

Abstract

Sapodilla fruit (Manilkara zapota) belongs to the Sapotaceae family. Sapodilla fruit is traditionally used in traditional medicine to cure typhoid and sapodilla fruit is not only made medicine but also the sap is taken as raw material for making chewing gum. The purpose of the examination was to determine the minimum inhibitory concentration (MIC) of sapodilla fruit extract against Salmonella typhi bacteria. The method used is the agar diffusion method using Mueller Hinton Agar (MHA) as a growth medium and paper backing. The results of the examination of the effective inhibition at a concentration of 300mg/ml with a diameter of 15.4 mm while the minimum inhibitory concentration (MIC) was at a concentration of 50mg/ml against Salmonella typhi with the smallest inhibitory diameter of 11.5 mm. From the data above, sapodilla fruit extract has a great inhibitory power against Salmonella typhi
ANALISA KADAR CEMARAN LOGAM MERKURI PADA IKAN SARDEN (Sardinella lemuru) KEMASAN KALENG SECARA SPEKTROFOTOMETRI SERAPAN ATOM (SSA) Silalahi, Yosy Cinthya Eriwaty; Thaib, Cut Masyithah; Nurbaya, Siti
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2714

Abstract

Food packaging in cans is a food preservation technology using high-temperature sterilization. Mercury is a heavy metal that can have a toxic effect on the body so it can cause death. This study aims to determine the levels of mercury contamination in canned sardines. The samples used in this study were 6 different brands of canned sardines. The method used to determine mercury (Hg) levels is qualitatively using color reagents and quantitatively using AAS (Atomic Absorption Spectrophotometry). The results obtained from 6 samples of canned sardines that were positive for heavy metal mercury (Hg) were indicated by the formation of orange color with KI reagent, yellow precipitate with NaOH, white precipitate with HCl. The wavelength used is 253.7 nm. The results showed that Brand A mercury 4.9814 ± 0.0301 mg/kg, Brand B 0.8757 ± 0.0308 mg/kg, Brand C 1.4899 ± 0 mg/kg, Brand D 1.4175 ± 0 mg/kg , Brand E 0.7527 ± 0 mg/kg, and Brand F 0.5270 ± 0 mg/kg. This study concludes that the mercury content in canned fish circulating in the Medan Brastagi Supermarket is above the maximum limit allowed by the National Standardization Agency (2016) in SNI 8222-2016, which is 0.5 mg/kg.
PERBANDINGAN UJI AKTIVITAS ANTI DIABETES EKSTRAK ETANOL BUAH PARE (Momordicacharantia L.) DAN DAUN LIDAH BUAYA (Aloe vera L.) PADA MENCIT JANTAN Sitompul, Erly; Supartiningsih, Supartiningsih; Harefa, Karnerius; Sari, Samsia Yolanda
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diabetes is a non-communicable degenerative disease that will increase in number in the future. This is evidenced by the increasing incidence of diabetes every decade. Bitter gourd and aloe vera are an alternative in treating Diabetes Mellitus because these plants contain saponins, flavonoids, and polyphenols (strong antioxidants), as well as glycosides cucurbitacin, momordicin, and charantin that can lower blood sugar, saponins, flavonoids, and alkaloids. This study aims to determine secondary metabolite compounds, anti-diabetic activity, and the combination of aloe vera extract and bitter melon extract that has antidiabetic activity. The method used in this study is an experimental method, namely testing the antidiabetic effect of extracts obtained from ethanol of bitter melon and aloe vera leaves on alloxan-induced mice. The results obtained from the research are that the administration of aloe vera extract 150 mg/kg BW and 200 mg/Kg BW, the group with the ethanol extract of bitter melon 150 mg/kg BW and 200 mg/Kg BW showed a very good effect on reducing BGD. This means that aloe vera extract 150 mg/kg BW and 200 mg/Kg BW, the group given ethanol extract of bitter melon 150 mg/kg BW and 200 mg/Kg BW had good antidiabetic activity.
PEMERIKSAAN JAMUR PADA ROTI ISI KACANG HIJAU YANG DIPERJUALBELIKAN DI PASAR SEI SIKAMBING MEDAN Sinaga, Eka Margaretha; Nasution, Pandapotan; Maimunah, Siti; Yanti, Surfin Putri
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v5i1.2727

Abstract

Green-bean filling bread is made from wheat flour and water and fermented with yeast. The presence of carbohydrates and sugar in bread causes mold to grow. This examination aims to determine the presence or absence of fungus on green bean sandwiches according to the SNI standard with no more than 104 microbial ingredients. The medium used in this examination is Potato Dextrose Agar (PDA) which has been added with 0.1% chloramphenicol. This examination uses an experimental method (parametric experiment). The sample in this examination is green bean stuffed bread traded in the Sei Sikambing market in Medan, the number of samples examined is 4 types from 2 shophouses in the Sei Sikambing market, Medan in 2015. The results of the examination showed the presence of fungal growth in all samples so the sample does not meet the requirements of SNI. To consume bread, you should pay attention to the condition of the bread at the time of buying.
FORMULASI SEDIAAN KRIM LULUR KOPI ARABIKA (Coffea arabica) SEBAGAI ANTI-AGING Purwandari, Vivi; Silitonga, Maringan; Thaib, Cut Masyithah; Sitohang, Isra Kristina
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v5i1.2728

Abstract

Coffee is one of the plantation commodities that has a fairly high economic value among other plantation crops and plays an important role as a source of foreign exchange for the country. Coffee contains important compounds such as antioxidants and caffeine which functions as anti-aging so that it can be used as an anti-aging ingredient in the form of a scrub. The purpose of this study was to determine whether coffee can be formulated in the form of cream as an anti-aging, and in the form of a body scrub cream. The research method using experimental includes the collection of Arabica coffee ingredients, making formulations of Arabica coffee scrub cream preparations, and description of the quality of Arabica coffee cream body scrub preparations. Data analysis in this study used descriptive analysis by presenting the frequency distribution table of each study. The results of the study found that the difference in the concentration of Arabica coffee (Coffea arabica) in body scrub cream preparations had an effect with the best concentration of 15% compared to 5%, 10%, and blank concentrations, and the use of body scrub cream preparations containing Arabica coffee. (Coffea arabica) 15% showed improvement in skin condition for the better, during four weeks of treatment. Thus, Arabica coffee (Coffea arabica) can be formulated in the form of body scrub cream as anti-aging.
IDENTIFIKASI CEMARAN LOGAM Sn (TIMAH) DALAM SUSU KENTAL MANIS KEMASAN KALENG Maimunah, Siti; Hafizullah, Ahmad; Simarmata, Yettrie
Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v5i2.2729

Abstract

Condensed milk or more commonly sweetened condensed milk is cow's milk in which the water is removed and sugar is added, resulting in milk that is very sweet in taste and can last for up to a year if not opened. In general, the term sweetened condensed milk means sweetened milk, namely milk in the form of a thick liquid, yellowish-white or other colors depending on the aroma added, with a distinctive smell and taste. This research was conducted to determine the presence or absence of metallic Sn (tin) in canned sweetened condensed milk in whole and dented cans. The samples examined were whole and dented canned sweetened condensed milk sold around Jalan Kapten Muslim Medan, the samples were taken randomly from three different brands. This study used a qualitative test method, the sample was ashed first using 0.1N HCl solvent, this research was carried out using 0.1N sodium hydroxide reagent there was no white or negative precipitate, using 0.1N sodium carbonate reagent there was no white precipitate or negative. Sweetened condensed milk sold around Jalan Kapten Muslim Medan does not contain Sn (tin) in the qualitative test, this shows that the sweetened condensed milk is safe for consumption.
FORMULASI SEDIAAN MASKER PEEL-OFF EKSTRAK DAUN PAKIS (Diplazium esculentum (Retz.)sw.) SEBAGAI ANTI-AGING Ghazali, Ahmad; Marpaung, Jon Kenedy; Adiansyah, Adiansyah; Sitorus, Carlos Salinas
Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v5i2.2730

Abstract

Tumbuhan pakis memiliki kandungan flavonoid, vitamin C, vitamin A, vitamin B kompleks, kalsium, dan fosfor. Flavonoid merupakan senyawa utama yang digunakan dalam sediaan masker gel peel-off sebagai anti-aging. Flavonoid mempunyai sifat sebagai antioksidan. Tujuan dari penilitian ini adalah memformulasikan dan mengevaluasi kemampuan masker gel peel-off ekstrak etanol daun pakis (Diplazium esculentum (Retz.)sw.) dalam memberikan efek anti-aging pada kulit wajah. Metode penelitian ini dilakukan secara eksperimental. Ekstrak etanol daun pakis diperoleh dengan cara maserasi menggunakan penyari etanol kemudian dipekatkan dengan rotary evaporator pada suhu 40, kemudian diformulasikan dalam sediaan masker gel peel-off dengan konsentrasi 2,5% (formula 1), 5% (formula 2), dan 7,5% (formula 3). Evaluasi terhadap sediaan masker gel peel-off meliputi pemeriksaan organoleptis, homogenitas, pengamatan stabilitas sediaan (perubahan warna, bau, pH dan waktu sediaan mongering dikulit) selama penyimpanan 4 minggu, uji viskositas, uji iritasi, dan uji efektifitas menggunakan alat skin analyzer terhadap kulit wajah. Parameter yang diukur meliputi kadar air, besar pori, jumlah noda, dan keriput. Perawatan dilakukan selama 4 minggu.Hasil penilitian menunjukkan bahwa ekstrak etanol daun pakis dapat diformulasikan sebagai masker gel peel-off. Hasil pemeriksaan kadar air yang terbaik adalah 7,5%, pori yang terbaik adalah 7,5%, penurunan noda yang terbaik pada konsentrasi 7,5%, dan penurunan keriput yang terbaik pada konsentrasi 5% terhadap pemakaian selama empat minggu.

Page 12 of 25 | Total Record : 248

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