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INDONESIA
Jurnal Farmanesia
Published by Universitas Sari Mutiara Indonesia
ISSN : """"     EISSN : 25282484     DOI : https://doi.org/10.51544/jf.v8i2
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmanesia dengan E-ISSN: 2528-2484 merupakan jurnal resmi yang diterbitkan oleh Program Studi S1 Farmasi Fakultas Farmasi dan Ilmu Kesehatan Universitas Sari Mutiara Indonesia, yang artikelnya dapat diakses dan diunduh secara online oleh publik (open access journal). Jurnal ini merupakan jurnal peer-review yang diterbitkan dua kali setahun dengan topik keunggulan hasil penelitian di bidang pelayanan dan praktik kefarmasian, teknologi farmasi, dan disiplin ilmu kesehatan yang berkaitan erat. Jurnal ini menerima teks bahasa Indonesia. Berikut ini adalah area penelitian yang menjadi fokus jurnal ini: 1. Farmakologi 2. Farmasetika 3. Biologi Farmasi 4. Kimia Farmasi 5. Farmakognosi 6. Fitokimia
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 248 Documents
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PENERAPAN METODE SPEKTROFOTOMETRI SERAPAN ATOM (SSA) DALAM MENGANALISIS LOGAM MERKURI (Hg) PADA KRIM PEMUTIH WAJAH Nurbaya, Siti; Safwan, Ahmad Gazali; Silitonga, Maringan
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2744

Abstract

Whitening cream is a mixture of chemicals and or other ingredients with properties that can fade dark spots on the skin. Whitening cream must be safe and must not contain harmful ingredients such as heavy metal mercury because its toxicity to the organs of the kidneys, nerves, and brain is very strong, so its use is prohibited in cosmetic preparations. The purpose of this study was to determine the levels of metallic mercury (Hg) contained in the preparation of facial whitening creams circulating in Sei Sikambing Market, Medan. The sample used in this study was a facial whitening cream that was not registered with BPOM. The method used to determine mercury levels is qualitatively using color reagents and quantitatively using AAS (Atomic Absorption Spectrophotometry). The results obtained were from 2 samples of facial whitening cream that were used positively for heavy metal mercury (Hg) characterized by the formation of a red-orange precipitate with KI reagent, yellow precipitate by NaOH reagent, white precipitate by HCl reagent. The results of the analysis showed that the highest Hg metal content in the sample with code E was 5.0241 ± 0.4064 g/g. The conclusion of this study is that two samples were positive for mercury, where the use of mercury has been prohibited by BPOM.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN SAMBUNG NYAWA (Gynura procumbens (Lour.)Merr.) TERHADAP BAKTERI Bacillus cereus ATCC 6633 Thaib, Cut Masyithah; Zuhairiah, Zuhairiah; Sianipar, Artha Yuliana; Simanullang, Eta M. Br
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2745

Abstract

Life-sustaining plants are plants that are widely used by people as natural medicines. Infectious disease is one of the problems in the health sector. Infection can be caused by various microorganisms, one of which is bacteria. This research was conducted at the Microbiology Laboratory, Sari Mutiara University, Indonesia. This study was conducted to examine the antibacterial activity of the ethanolic extract of life-sustaining leaves using the paper disc diffusion method with concentration variants of 20%, 30%, 40%, 50%, and 60% and used a negative control of DMSO and positive control of chloramphenicol. From the research that has been done, the extract of the continued life leaves has antibacterial inhibitory power. At a concentration of 20% (10 mm). At a concentration of 30% (11 mm). At a concentration of 40% (12.67 mm). At a concentration of 50% (13.3 mm). At a concentration of 60% (15.3 mm). It can be concluded that the ethanolic extract of the grafted life leaves has the highest antibacterial inhibition at a concentration of 60%, which is 15.3 mm.
PENETAPAN KADAR NITRAT PADA IKAN KALENG SARDEN SECARA SPEKTROFOTOMETRI VISIBLE Simarmata, Yettrie; Nurbaya, Siti; Purwandari, Vivi
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2747

Abstract

Canned fish is a food that is synonymous with preservatives and food coloring. In the manufacturing process, manufacturers often use natural preservatives to lower production costs. This research is descriptive research. The research location is at PT. Mutifa. Aims to determine how much nitrate levels in branded canned sardines are sold at supermarkets in the city of Stabat whether they meet the requirements of SNI or not. From the results of the study, the levels of nitrate with Brand A were 0.00694% and sardines with Brand B were 0.0453% with a maximum wavelength of 435 nm. According to regulations set by the government according to SNI Number 01-35481994 nitrate levels should not be more than 0.2%. From all samples of canned sardines studied, it was found that nitrate levels were low and did not exceed SNI requirements.
ANALISIS TIMBAL (Pb) DAN KADMIUM (Cd) PADA KERANG BULUYANG DIPEROLEH DARI PASAR SEI SIKAMBING MEDAN SECARA KUALITATIF Maimunah, Siti; Sianipar, Artha Yuliana; Zuhairiah, Zuhairiah; Silalahi, Yosy Cinthya Eriwaty
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2748

Abstract

Shellfish (Anadaraantiquata) is one type of shellfish that has the potential to be used as a food source in fulfilling the nutrition of the Indonesian people. Feather clams (Anadaraantiquata) belong to the class Bivalvia which are edible and have economic value. The purpose of this study was to determine the content of lead and cadmium in feather shells. Samples were taken from two fur shell traders at the Sei Sikambing market in Medan using a random sampling method with qualitative testing using disodium sulfide, potassium iodide, potassium chromate, potassium cyanide, and sodium hydroxide reagents, in accordance with work procedures. used in the Medan Regional Health Laboratory. The results showed that of the two samples tested, both samples did not contain lead (Pb) and cadmium (Cd). Keywords: Feather shells, lead (Pb), Cadmium (Cd), Qualitative.
ANALISA KADAR CEMARAN MERKURI (Hg) PADA IKAN TUNA (Thunnus sp.) KEMASAN KALENG SECARA SPEKTROFOTOMETRI SERAPAN ATOM (SSA) Adiansyah, Adiansyah; Silalahi, Yosy Cinthya Eriwaty; Ritonga, Ahmad Hafizullah
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2750

Abstract

Mercury is a heavy metal that can have a toxic effect on the body so that it can cause death. Mercury metal contamination in food is regulated in SNI number 7387 of 2009 regarding the Maximum Heavy Metal Limit. Some metal waste disposal ends up in river, lake, or sea waters so that metal pollution can occur in the ecosystem. This study aims to determine the levels of mercury metal contamination in canned tuna. Sample preparation was carried out using the wet digestion method with a microwave digestion device. The results of the analysis showed that from the six samples of canned tuna fish according to the maximum limit and meet the standard maximum limit of 1.0 mg/kg SNI. Mercury analysis was carried out using the AAS (Atomic Absorption Spectrophotometry) method. The wavelength used is at 253.7 nm. The results showed that the mercury in tuna brand A was 0.9030±0 mg/kg tuna brand B 0.1029±0 mg/kg, tuna brand C 0.4524±0 mg/kg, tuna brand C D 0.0967±0 mg/kg, tuna brand E 0.9567 ± 0 mg/kg, and tuna brand F 0.8034±0 mg/kg.
ISOLASI MINYAK ATSIRI BIJI BUAH PALA (Myristica fragrans Houtt) DAN PENGGUNAANNYA DALAM PEMBUATAN SABUN TRANSPARAN YANG DI KOMBINASIKAN DENGAN MINYAK JARAK Yuniarti, Rafita; Lubis, Minda Sari; Anggraini, Dea Puspa
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2751

Abstract

Nutmeg oil is an essential oil produced through the distillation process from dried nutmeg seeds. Nutmeg oil is usually obtained after the fat contained in it is removed first. Nutmeg oil is used in the pharmaceutical industry as a remedy for stomach aches and diarrhea. The development of castor oil in Indonesia has been increasingly widespread, but its utilization has not been maximized. To maximize the utilization of castor oil, castor oil is processed into soap. Castor oil is always used in the manufacture of transparent soap because castor oil can provide transparent properties to soap. Soap is a surfactant that is used with water for cleaning and washing. The purpose of this study was to use nutmeg essential oil as a comparison with castor oil in making transparent soap. The research method used is experimental. Making transparent soap using nutmeg essential oil as a comparison with castor oil, the amount of nutmeg essential oil and castor oil used was 5ml, 10ml, 15ml, 20ml. Tests of soap preparations made include organoleptic tests, water content tests, pH tests, mineral oil tests, high foam tests and free fatty acid/free alkali tests. From the results of the tests carried out, it can be concluded that the ratio of nutmeg oil and castor oil which has the best concentration is the concentration of 5ml jatropha: 15ml nutmeg. This comparison meets the requirements, namely the results of organoleptic tests that produce good shape, smell and color, the results of the water content test produce 5.5%, the pH test results produce 8. the mineral oil test results were negative, the foaming power and foam stability test results were fixed at 285 and the free alkali test results were 0.039
FORMULASI SEDIAAN GEL MASKER WAJAH DARI BAHAN ALAM EKSTRAK RIMPANG TEMU MANGGA(Curcumaamada) Maringan, Maringan; Sitorus, Erly Nurita; Thaib, Cut Masyithah; Afrilla, Cut Windy
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2752

Abstract

Temu manggais a plantthat has a highantioxidant content. One type of antioxidant in temu manggais vitamin E which can rejuvenate the skin. There are manyuseful ingredients in the temu mangorhizome, namel ycurcumin, flavonoids, tannins, saponinsandes sential oils. This research method was carried out experimentally. The temu mangga rhizomewas extractedusing 70% ethanolsolventbymaceration method then concentrate dusing a rotary evaporator. The extractof temu mangga rhizome was then formulate dinto a gel maskwith a concentrationof F0 as a blank, using a base gel mask without extractand with the addition of F1 (1%) and F2 (3%) extracts. Evaluationof gel mask preparations includesorganoleptictests, namely observing with the five human sensessuch as odor, color, shape, pH test, homogeneity, dryingtimetest, irritationtest, and effectiveness test as a facial moisturizer using a skin analyzeron the facial skin of volunteers. Parameters measured include moisturecontent, poresize, and wrinkles. The resultsof this study indicate that the gel maskpreparation has a drying time of 20-30 minutes, isstablefor 4 weeks of storage anddoes not irritatethe skin. The measure mentresults of facial moisturizing activity showed that 3% extra gel mask was the best by increasing water content, shrinkingporeson facial skin and reducing wrinkleson the face
PEMBUATAN KERTAS RAMAH LINGKUNGAN KOMBINASI LIMBAH AMPAS TAHU DAN LIMBAH KULIT PISANG KEPOK DENGAN METODE PEMISAHAN ALKALISASI Aritonang, Barita; Sinaga, Eka M; Supartiningsih, Supartiningsih; Sitorus, Elly
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2753

Abstract

Tofu dregs waste contains 30.4% cellulose content, while kepok banana peel has high cellulose content (60-65%), hemicellulose 6-8%, and lignin 5-10%. The purpose of this study was to determine the process of making natural paper from tofu dregs waste and kepok banana peel waste as an alternative raw material for wood substitutes and to find out the characteristics of natural paper produced from tofu waste fiber and kepok banana peel waste based on SNI 287:2010 (including test water content) and SNI 6588-1:2010 (including pH acidity test). Based on the results of research that has been carried out, the optimum composition in making paper from tofu dregs and kepok banana peels is 50:50% variation. The temperature and time of heating and the optimum concentration of sodium hydroxide solution was 120 oC for 90 minutes with sodium hydroxide solution concentration of 10.0%, pulp content of 46.45%, cellulose content of 53.3%, and lignin content of 46.67%. All levels obtained have met the requirements of SNI. Based on the FT-IR spectrum analysis, tofu dregs and kepok banana peels are suitable for use as raw materials for making paper because they contain cellulose. Based on the SEM analysis, the morphological surface structure, the tighter the fiber bonds, this proves that the diameter of the resulting fiber is very small, because the smaller the fiber diameter, the better the mechanical properties.
IDENTIFIKASI ANTALGIN DALAM JAMU PEGAL LINU SECARA KROMATOGRAFI LAPIS TIPIS Supartiningsih, Supartiningsih; Sinaga, Eka Margaret; Silitonga, Maringan
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2754

Abstract

Traditional medicine is an ingredient or ingredient in the form of plant material, animal material, mineral material, preparation of extracts (galenic), or a mixture of these materials which have been used for generations. Jamu is traditional medicine, in general, herbal medicine cannot cure all kinds of diseases and its natural effect is not as fast as chemical drugs. Lately, medicinal chemicals are often added which are prohibited under the provisions of BPOM (Food and Drug Supervisory Agency). Antalgin is an analgesic-antipyretic and anti-inflammatory drug. Identification of antalgin in herbal aches and pains by thin layer chromatography aims to determine whether the herbal aches and pains circulating around Jalan Captain Muslim, Medan city contain levorphanoll drug chemicals or not. Antalgin identification in herbal pain relief was applied using Thin Layer Chromatography method with 60 F Silica gel stationary phase and chloroform-acetone-toluene (65: 25:10) mobile phase. From the results of identification by thin-layer chromatography (TLC) on herbal pain relief, it was found that the Rf value of the chromatogram spot on the levorphanol 0.16 reference standard was close to the sample Rf value (E) of 0.12. Based on the examination that has been carried out, it can be concluded that the positive herbal pain relief contains levorphanol drug chemicals so that the sample (E) tested does not meet the requirements.
PENETAPAN KADAR NATRIUM PADA BUAH PISANG EMAS (Musa acuminate Colla.) SECARA SPEKTROFOTOMETRI SERAPAN ATOM Purwandari, Vivi; Hafizullah, Ahmad; Sofwan, Ahmad Gazali; Simanjuntak, Nelson; Veronica, Wantri
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2755

Abstract

Bananas are the most consumed fruit by the people of Indonesia. This fruit has many health benefits including improving digestion, treating anemia, healthy bones, and improving nerve function. The nutritional content contained in bananas is carbohydrates, sugar, dietary fiber, fat, protein, vitamins, and minerals such as sodium, calcium, magnesium, phosphorus, potassium, and zinc. This study aims to determine the sodium content in golden bananas. The assay was carried out using an air-acetylene flame atomic absorption spectrophotometer. Quantitative analysis of sodium was carried out at a wavelength of 589.6 nm. The results of the study concluded that the sodium content of golden bananas was 1.8647 mg/100g. The results of the relative standard deviation test are 15% and have good precision because the results obtained for analytes with levels of parts per million are not more than 16% (Harmita, 2004).

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