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INDONESIA
Jurnal Farmanesia
Published by Universitas Sari Mutiara Indonesia
ISSN : """"     EISSN : 25282484     DOI : https://doi.org/10.51544/jf.v8i2
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmanesia dengan E-ISSN: 2528-2484 merupakan jurnal resmi yang diterbitkan oleh Program Studi S1 Farmasi Fakultas Farmasi dan Ilmu Kesehatan Universitas Sari Mutiara Indonesia, yang artikelnya dapat diakses dan diunduh secara online oleh publik (open access journal). Jurnal ini merupakan jurnal peer-review yang diterbitkan dua kali setahun dengan topik keunggulan hasil penelitian di bidang pelayanan dan praktik kefarmasian, teknologi farmasi, dan disiplin ilmu kesehatan yang berkaitan erat. Jurnal ini menerima teks bahasa Indonesia. Berikut ini adalah area penelitian yang menjadi fokus jurnal ini: 1. Farmakologi 2. Farmasetika 3. Biologi Farmasi 4. Kimia Farmasi 5. Farmakognosi 6. Fitokimia
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 248 Documents
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UJI EFEKTIVITAS ANTIBAKTERI NANO GEL BAHAN AKTIF EKSTRAK KAYU MANIS (Cinnamomum burmannii) TERHADAP Staphylococcus aureus Purwandari, Vivi; Sianipar, Artha Yuliana; Silalahi, Yosy Cinthya Eriwaty; Nasution, Dinda Juita
Jurnal Farmanesia Vol 7 No 2 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i2.2776

Abstract

Nanogel preparations consist of nanoemulsions and gels, where nanoemulsion is one type of preparation that can increase drug permeability on the membrane surface. The use of cinnamon extract as an antibacterial active substance is because cinnamon (Cinnamomum burmannii) contains saponins, tannins, and flavonoids. This study aims to make nanogel preparations with the active ingredient of cinnamon extract and to determine the antibacterial effectiveness of the nanogel as the active ingredient of the cinnamon extract against Staphylococcus aureus. The manufacture of 2% cinnamon extract nanoemulsion aims to make nanoparticle-sized nanogel preparations and as an antibacterial active substance in nanogel preparations against Staphylococcus aureus bacteria. Nanogel preparations were made by adding cinnamon extract nanoemulsion with varying concentrations of F1(2%), F2(4%), F3(6%), and blank formula (F0) as the basis for nanogels without cinnamon extract nanoemulsion. The results showed that the cinnamon extract nanoemulsion could be made into nanogels to produce a thick, brown-colored gel with a characteristic cinnamon smell. The result of the pH of the preparation is 6 according to the pH of the skin, has good homogeneity, and is not irritating to the skin. The PSA test produces a nanoparticle size of 24.2 nm, and the antibacterial effectiveness test of the nanogel preparation can inhibit Staphylococcus aureus bacteria. Produced a moderate inhibition zone category (6.7-7.1 mm) and the F3 formulation (6%) was the best formulation.
PENENTUAN KADAR PROTEIN PADA SUSU KEDELAI (Glycinemax L. Merril) DENGAN MENGGUNAKAN METODE Kjeldahl Nurbaya, Siti; Supartiningsih, Supartiningsih; Hafizullah, Ahmad
Jurnal Farmanesia Vol 7 No 2 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i2.2777

Abstract

Soy milk has a combination of nutrients that are almost the same as cow's milk, but soy milk has low cholesterol, gluten, and lactose levels so that soy milk is safe for consumption by people with lactose intolerance, vegetarians, and is also safe for health. Determination of protein content that is most often done is the determination of crude protein which aims to determine the total amount of protein in food ingredients. The most commonly used protein assay method is the Kjeldahlmethod. This study aims to determine the protein content of soy milk packaged in boxes that are made by themselves and sold in traditional markets. The samples used in this study used packaged soy milk, traditional soy milk, and homemade soy milk. The results showed that the protein content of the three samples determined by the Kjeldahlmethod was 3.35±0.0816% traditional soy milk, 2.31±0.3562% box-packed soy milk, and 2.62±0.2495% whole milk. Homemade soybeans. The protein content in box-packed soy milk, homemade soy milk, and traditional soy milk haveeach met the requirements of SNI (1995). The results showed that the protein content of traditional soy milk was greater than that of packaged soy milk and homemade soy milk.
PENENTUAN KADAR KAFEIN DALAM KOPI INSTAN SECARA SPEKTROFOTOMETRI ULTRAVIOLET Supartiningsih, Supartiningsih; Zuhairiah, Zuhairiah; Thaib, Cut Masyithah
Jurnal Farmanesia Vol 7 No 2 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i2.2778

Abstract

Caffeine in coffee has clinically beneficial pharmacological effects, such as stimulating the central nervous system, relieving fatigue, drowsiness and also increasing concentration. However, excessive use of caffeine can cause heart palpitations and stomach upset. According to SNI 01-7152-2006, the maximum limit of caffeine in food and beverages is 150 mg/day and 50 mg/serving. The purpose of this study was to determine the level of caffeine in instant coffee circulating in supermarkets in Medan City by Ultraviolet Spectrophotometry. Determination of caffeine content was carried out by the UV Spectrophotometry method after extraction using chloroform in an alkaline environment. The caffeine concentration can be calculated from the calibration curve regression equation. The results showed that the three instant coffee samples were determined to have different levels of caffeine, namely instant coffee sample code A 5.2585 mg/gram, code sample B 4.2348 mg/gram, and code C 133564. mg/gram. When viewed from the requirements, the caffeine content in the instant coffee samples coded A and B has exceeded the portion limit of 131.4625 mg and 84,768 mg, respectively, but is still within the limits set by SNI 01-7152-2006 if consumed in one pack. per day, henceforth the code C sample does not exceed the caffeine content limit of serving, which is 26.7128 mg of caffeine.
UJI KEAMANAN PRODUK TERHADAP KULIT DAN TINGKAT KESUKAAN REMAJA TERHADAP PRODUK KOSMETIK GEL PEMBERSIH WAJAH Sitorus, Elly Nurita; Thaib, Cut Masyithah; Sofwan, Ahmad Gazali
Jurnal Farmanesia Vol 8 No 1 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i1.2779

Abstract

Cosmetics are used on the external parts of the human body (epidermis, hair, nails, lips, and external genital organs) or on the teeth and oral mucosa mainly to clean, perfume, change appearance and/or improve body odor or protect and maintain the body in good condition. There are many types of fake cosmetics on the market today, there are cosmetics that are circulating in the market illegally (not having a BPOM permit) which are dangerous for users. This study aims to determine the level of preference for the use of several facial cleansing gel cosmetic products and to determine the effect of different active ingredients on the level of preference of several facial cleansing gel products. The sample used in this study were 30 female adolescents aged 15-23 years. The research method used in this research is descriptive method with data collection techniques in the form of questionnaires and observations. The results showed that all facial cleansing gel cosmetic products used in this study had passed the BPOM notification and did not experience irritation on the respondent's skin when the irritation test was carried out for 2 x 24 hours. At the level of preference for cosmetic products seen from the overall product parameters, the respondents most preferred were Brand A Products, which were 362, then Brand B Products were 356, then Brand C Products were 320.
UJI AKTIVITAS ANTIBAKTERI MADU HUTAN TERHADAP BAKTERI Bacillus cereus Maimunah, Siti; Supartiningsih, Supartiningsih; Marpaung, Jon Kenedy; Silalahi, Yosy Cinthya Eriwaty; Turnip, Icha Wahyuni
Jurnal Farmanesia Vol 8 No 1 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i1.2780

Abstract

Honey is a thick sweet liquid which comes from bees which can cure many diseases and is antibacterial. Antibacterial potential of honey caused by the content of active compounds, low moisture content, high osmolarity, hydrogen peroxide content, and low pH.The aim of this study was to determine the antibacterial activity of forest honey on Doloksaribu, Simalungun district on the growth of Bacillus cereus bacteria.Experiment research method includes the analysis quality of honey, includes checking moisture content, ash content, pH tested, acidity, viscosity, spesific gravityphytochemical screening, and antibacterial activity test ith disk diffusion method use blank disk with each concentration 25%, 35%, 45%, 55%, and 65%, positive control using erythromycin and negative control sterile distilled water. Organoleptic test conducted on forest honey gave results that honey reach the requirements for good quality. The result of moisture and ash content test and pH test reach of SNI 3545: 2013 about honey. Antibacterial activity test of forest honey with concentration 25%, 35%, 45%, 55%, and 65% against Bacillus cereus showed that there was an inhibitory around the blank disc, namely 10,16 mm, 13 mm, 15,6 mm, 21,6 mm, and 22,6 mm. The greatest inhibition of forest honey occurred at the highest concentration that is 65% (22,6 mm).
PENENTUAN KADAR DAN VALIDASI METODE SPEKTROFOTOMETRI ULTRAVIOLET PADA SEDIAAN TABLET BROMHEKSIN DARI BEBERAPA INDUSTRI FARMASI Miswanda, Dikki; Ridwanto, Ridwanto; Mulyani, Riski
Jurnal Farmanesia Vol 8 No 1 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i1.2781

Abstract

Bromhexine works by increasing the amount of mucus and reducing its viscosity. In Pharmacopoeia Edition V (2014) there is no monograph of bromhexine either in syrup form or in tablet preparation. Bromhexine has chromophore and auxochrome groups in its structure so that this compound can absorb radiation in the ultraviolet (UV) region. The purpose of this study is to find an alternative method that is simple and inexpensive but provides good accuracy and precision. This method was validated and then the validated method was applied to the assay of bromhexine tablets on the market. The method used was ultraviolet spectrophotometry with 0.1 N HCl as a solvent. The sample used was 5 bromhexine tablets with trade names. The validation test parameters carried out are accuracy, precision, detection limits and quantitation limits. The results of the specified validation test provide an accuracy test with a percent recovery of 101.14% and a Relative Standard Deviation (RSD) of 1.6964%. This shows that this method provides good accuracy and precision, with a limit of detection (LOD) of 0.6315 and a limit of quantitation (LOQ) of 1.1983. The assay results of the tablet sample of the trade name Bisolvon (PT. Boehringer Ingelheim) 100.70% -+ 0.56%; Bromifar (PT. Ifars) 101.09% -+ 0.44%; Bronchitis (PT. Graha Farma) 100.65% -+ 0.67%; Mucohexin (PT. Sanbe) 100.92% -+1.25% and Omesolvon (PT. Mutifa) 100.34% -+ 0.37%. All tablets determined to meet the requirements of the general content of a tablet that is not less than 90% and not more than 110% of the amount stated on the label.
PENETAPAN KADAR KAFEIN DARI BUBUK KOPI YANG DIPEROLEH DARI KOTA SIDIKALANG SECARA SPEKTROFOTOMETRI UV Maimunah, Siti; Supartiningsih, Supartiningsih; Chandra, Devina
Jurnal Farmanesia Vol 8 No 1 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i1.2782

Abstract

Coffee has many health benefits, such as stimulating the central nervous system, with the effect of relieving fatigue, drowsiness, and also in creasing concentration power. How ever, excessiveuse of caffeine can cause heart palpitations, stomachdi sorders, and shaking hands. Caffeine levels in coffee circulating in the market vary, dueto a mixtureofotheringredients. For this reason, the National Standardization Agency (BSN) has set a standard for caffeine content in coffeepowder, whichis 0.455%-2% w/w (SNI 01-3542-2004), so that if there is coffee containing high levels of caffeine, it needs to be decaffeinated. tosuppresstheactivityofcaffeine in thebody. The purpose of this study was to determine the caffeine content of Arabica coffee powder and Robusta coffee. The samples determined were 2 types of arabica coffee powder, namely those obtained from high stems and low stems, and 1 robusta coffee powder. Sampling was carried out purposively, and as says were determined using ultraviolet spectrophotometry after extraction using chloroform. The results showed that the caffeine content of high-stem Arabica coffee powder was 1.675% (16.75mg/g), low-stemmed 0.546% (5.462 mg/g), and 0.818% (8.18mg/g) of Robusta coffeegrounds. In conclusion, the caffeine levels of the three samples determinedmet the requirements of the Indonesian National Standard.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KEMANGI (Ocimumbasilicum L.) TERHADAP PERTUMBUHAN BAKTERI Staphylococcusaureus Manurung, Kesaktian; Marpaung, Jon Kenedy; Harefa, Karnerius; Mardianis, Mardianis
Jurnal Farmanesia Vol 8 No 1 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i1.2784

Abstract

Basil (Ocimumbasilicum L.) is one of the natural plants that is easily obtained in Asia such as Indonesia which has medicinal properties. Basil leaves contain flavonoid compounds, tannins, saponins, and steroids/triterpenoids. These compounds are known to have antibacterial activity. This study aims to determine the antibacterial activity of the ethanolic extract of basil leaves (Ocimumbasilicum L.) against Staphylococcus aureus bacteria. This research is experimental. The test was carried out through several stages including material collection, preparation of simplicia, making ethanol extract of basil leaves, and testing the inhibitory power of basil leaves against Staphylococcus aureus bacteria. The ethanol extract of basil leaves was made by the maceration method using 96% ethanol and concentrated with a rotary evaporator to obtain a thick extract from basil leaves. Antibacterial activity was tested by the agar diffusion method using disc paper. The results of the antibacterial activity test showed that the ethanolic extract of basil leaves inhibited the growth of Staphylococcus aureus bacteria at concentrations of extracts of 5%, 10%, 15%, 20%, and 25% with inhibition zone diameters of 8. 31 mm, 9. 43 mm, respectively. 9. 73 mm, 9. 91 mm, and 11. 33 mm. The ethanol extract of basil leaves has antibacterial activity against Staphylococcus aureus bacteria.
PEMERIKSAAN CEMARAN Escherichia coli, Shigella sp DAN Salmonella sp PADA SUSU SAPI PERAH YANG DIPEROLEH DARI PETERNAKAN ASAM KUMBANG KECAMATAN MEDAN SELAYANG Zuhairiah, Zuhairiah; Maimunah, Siti; Silitonga, Maringan
Jurnal Farmanesia Vol 8 No 1 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i1.2785

Abstract

Milk is a drink that is mandatory for consumption by the public, especially for children, therefore, milk must be free from contamination with Escherichia coli, Shigella sp and Salmonella sp bacteria, through the tools used are not clean, the environment is dirty, the hands of workers, and others. This study aims to determine the presence or absence of Escherichia coli, Shigella sp, and Salmonella sp bacteria in Dairy Cow Milk obtained from the Asam Kumbang Farm, Medan Selayang District. The research sample was ten samples of milk from dairy cows in one farm with different cows which were treated with two aseptic and non-aseptic treatments. The research method used is descriptive research with MPN (Most Probable Number) method to count coliform bacteria followed by an examination of LB, BGLB, EMBA media, gram staining, biochemical tests, IMVIC tests, and user testing methods on samples of Shigella sp and Salmonella bacteria sp followed by an examination of NB, SCB, SSA media, gram staining, biochemical tests, and IMVIC. The results showed that one aseptic sample A and 3 non-aseptic samples A, B, C had Escherichia coli bacteria in dairy cows' milk. The quality of milk must comply with the requirements of SNI 3141.1:2011 Fresh Milk Quality and the Maximum Limit of Microbial Contamination in SNI 7388-2009 Fresh Milk.
HUBUNGAN PELAYANAN KEFARMASIAN TERHADAP KEPUASAN PASIEN PENGGUNA OBAT ANTI TUBERKULOSIS (OAT) DI UPT PUSKESMAS TITIPAPAN TAHUN 2021 Manurung, Kesaktian; Sinaga, Taruli Rohana; Thaib, Cut Masyithah; Monica, Yohana
Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i2.2789

Abstract

. Patient satisfaction is the match between expectations and the reality felt by the patient. Pharmaceutical service is a direct and responsible service to patients, related to pharmaceutical preparations with the aim of achieving definite results to improve the quality of life of patients. The purpose of this study was to determine the level of patient satisfaction at UPT Puskesmas Titipapan and to determine the relationship between pharmaceutical services and patient satisfaction at UPT Puskesmas Titipapan. The population in this study were OAT users who were treated at UPT Puskesmas Titipapan Medan during this study. With an average number of 31 patients per month. The number of samples in this study was determined using theformula in slovin order to obtain a sample of as many as respondents who visited the UPT Puskesmas Titipapan. This research is a descriptive research with quantitative methods. The type of approach used is a cross sectional design, namely a research design that collects data at one time to the sample. The results of this study were the level of patient satisfaction at the UPT Puskesmas Titipapan Medan, 71.0% of patients felt very satisfied. Of the 25 patients (80.6%) who received good service, 9 patients (29.0%) were satisfied. Based on the statistical analysis of these values indicate that the level of quality pharmaceutical services provided by the UPT Puskesmas TitipapanPengg Patients AgainstunaAnti- Tuberculosis Drugs (AOT) is less significant.

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