cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
debie anggraini
Contact Email
scientificj.id@gmail.com
Phone
+6281277167619
Journal Mail Official
scientific.journal@scientic.id
Editorial Address
Jalan Khatib Sulaiman, Kel. Alai Parak Kopi, Kec. Padang Utara, Kota Padang, Provinsi Sumatera Barat
Location
Kota padang,
Sumatera barat
INDONESIA
Scientific Journal
Published by CV. Akhbar Putra Mandiri
ISSN : 28100204     EISSN : 28100204     DOI : https://doi.org/10.56260/sciena
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Scientific Journal(SCIENA) published by an official of Scientific.id_considers the following types of original contribution for peer review and publication: Research Articles, Review Articles, Letters to Editor, Brief Communications, Case Reports, Book Reviews, Technological Reports, and Opinion Articles. It Is published six times a year and serves the need of scientific and non-scientific personals involved/interested in Natural Science (Physics, Chemistry, Electronics, Mathematics, Astronomy, Oceanography, Engineering), Social Science, Economics, Biology and Medicine. Each issue covers topics, which are of broad readership interest to personals from General Public, Industry, Clinicians, Academia, and Government. Scientic Journal is a must read journal for every one with curiosity in science.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 221 Documents
 19   20   21   22   23 
Etnobotani Tumbuhan Obat di Nagari Mungka Kecamatan Mungka Kabupaten Lima Puluh Kota Farras, Fadhila Annisa; Putri, Dwi Hilda; Chatri , Moralita; Handayani , Dezi
Scientific Journal Vol. 5 No. 2 (2026): SCIENA Volume V No 2, March 2026
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v5i2.318

Abstract

Pendahuluan: Tumbuhan Obat merupakan tumbuhan yang digunakan sebagai bahan baku pengobatan dalam mengatasi penyakit. Tujuan penelitian: Mengetahui jenis-jenis tumbuhan obat, organ tumbuhan yang digunakan serta khasiat dan cara penggunaannya di Nagari Mungka. Metode : Jenis penelitian ini adalah deskriptif eksploratif. Sampel penelitian ini berjumlah 23 responden. Analisis data secara kualitatif dengan dukungan pustaka ilmiah, kemudian data yang diperoleh disajikan dalam bentuk tabel. Hasil : ditemukan 39 jenis tumbuhan obat yang terdiri dari 29 familia. Tumbuhan obat yang banyak ditemukan yaitu familia Euphorbiaceae, Fabaceae, Lamiaceae masing-masing sebanyak 3 species, Organ tumbuhan yang banyak digunakan adalah daun. Cara pengolahan tumbuhan obat yang digunakan dengan cara direbus, dibakar, digiling atau dihaluskan, dihancurkan, dan diremas. Sedangkan untuk pemanfaatan tumbuhan obat ada yang diminum, diurut, diusap, dioles, dtempel, digosok dan dikonsumsi langsung. Kesimpulan : Masyarakat di Nagari Mungka masih memanfaatkan tumbuhan sebagai obat tradisional.
Tinjauan Pustakaa Peranan ACEIs. ARB dan ARNI pada Penyakit Ginjal Kronik Wahyudi, Adefri; Wahyudi
Scientific Journal Vol. 5 No. 2 (2026): SCIENA Volume V No 2, March 2026
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v5i2.322

Abstract

Latar Belakang: Penyakit ginjal kronik (PGK) dan penyakit kardiovaskular (PKV) merupakan dua kondisi berkaitan dan sering muncul bersamaan. Penggunaan obat yang bekerja di sistem renin angiotensin aldosteron (RAA) eperti golongan ACEIs, ARB, dan ARNI merupakan pilihan utama  pada hipertensi dan bagian pilar utama terapi pada gagal jantung fraksi ejeksi rendah. Efek samping hiperkalemia dan peningkatan kreatinin serum sering menjadi alasan bagi klinisi untuk tidak memberikan ACEIs/ARB pada pasien PGK. Metode: Pendekatan narrative review, sumber literatur dari Pubmed, Google Scholar dan Science Direct dengan kata kunci PGK, PKV, RAAS inhibitor. Kriteria inklusi berupa artikel sesuai tema penelitian, artikel terindeks scopus dan diterbitkan tahun 2016 – 2025. Kriteria eksklusi meliputi artikel yang tidak dapat diakses, tidak menjawab jenis review. Hasil: Penggunaan obat yang bekerja di sistem RAA pada PGK aman dan memberikan outcome yang baik. Penghentian terapi akan meningkatkan risiko progresivitas end stage renal disease (ERSD) 1,29 kali dan insiden PKV 1,38 kali. Kesimpulan: Penggunaan obat yang bekerja di sistem RAA seperti golongan ACEIs, ARB, dan ARNI pada pasien PGK aman, efektif dan memberikan outcome yang lebih baik.
A Case of Onychomycosis with Nail Lichen Planus: The Importance of Supportive Examinations in Establishing a Diagnosis Ariani, Tutty; Farhanah, Nindya; Gustia, Rina
Scientific Journal Vol. 5 No. 1 (2026): SCIENA Volume V No 1, January 2026
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v5i1.325

Abstract

Background: Onychomycosis and Nail Lichen Planus (NLP) are two conditions that cause nail damage and may sometimes present with overlapping clinical features, leading to difficulties in achieving an accurate diagnosis. Several ancillary examinations should be considered to avoid misdiagnosis of nail disorders. Case: A 64-year-old female patient presented to the Dermatology, Venereology, and Aesthetic Clinic at Dr. M. Djamil General Hospital Padang with complaints of progressive nail thickening and whitening affecting almost all nails, occasionally accompanied by itching, for the past 6 months. The patient had previously been diagnosed with onychomycosis and had regularly taken fluconazole 150 mg weekly for 6 months, but without improvement. Physical examination was within normal limits. Dermatological and onychoscopic examination revealed subungual hyperkeratosis, longitudinal ridging, onychotrophy, onychoschizia, trachyonychia, onycholysis, yellowish discoloration, melanonychia, and leukonychia, with an OSI score indicating severe involvement and a NALSI score of 100/120. KOH examination demonstrated the presence of hyphae, fungal culture revealed Aspergillus niger, PAS staining confirmed fungal elements, while biopsy results were consistent with NLP. The patient was diagnosed with onychomycosis with concomitant NLP and was treated with pulse itraconazole at a dose of 400 mg/day for one week each month for 2–3 months. Upon completion, treatment for NLP was initiated. Discussion: In this case, the absence of comprehensive ancillary examinations particularly biopsy, initially led to a diagnosis limited only to onychomycosis, without recognition of the coexisting NLP. This highlights the importance of thorough investigations to ensure an accurate and precise diagnosis.
A A Method to Quantify Biofilms in Object Glass Using ImageJ Wicaksono, Arief Heru; Risandiansyah, Rio; Hakim, Reza; Syarieb, Ahmad Akbar; Kurniawati, Annisa; Shafira , Iftah Ghina; Maulani , Maghfirah Nur; Primadita, Hanggia
Scientific Journal Vol. 5 No. 2 (2026): SCIENA Volume V No 2, March 2026
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v5i2.330

Abstract

  Background: Direct microscopic observation of biofilms is done by observing for the presence of biofilm under a microscope. However, this method is qualitative and not quantitative. Analysis of these biofilm structures using image processing software may provide a method to quantify biofilm production and degradation in glass slides. Objective: To quantify the number and area percentage of microbial structures observable on a slide. This study is an experimental in vitro study. Methods: Biofilm production was done by submerging slides in petri dishes filled with Brain Heart Infusion with 2% sucrose (w/v) and inoculating it with Staphylococcus aureus. The petri dishes were incubated undisturbed for 48 hours at 37°C (n=3).The slides were then submerged in distilled water (Group 1) or detergent (Group 2) for 5 minutes before staining with 0.1% crystal violet and observed under a light microscope at 1000x. Images from five fields of view were collected. ImageJ was then used to count the number of microcolonies, aggregate cells, and single cells or cell clusters, based on size, and their respective area percentage. Welch’s T-Test was performed using JASP version 0.18.3. Results: Direct observation of slides shows that microcolonies and cell clusters to be formed in Group 1, and none or little in Group 2, indicating differences in biofilm formation on Group 1 vs Group 2.Based on ImageJ calculation, control slides had an average percentage area for microcolonies, cell agregates, and single cells or clusters of 39.97 ± 9.99%, 8.96 ± 3.19%, and 1.39 ± 0.33%, respectively. Treatment with detergent significantly reduced percentages of microcolonies to 0.33 ± 0.68%, but increased single cell area to 5.27 ± 0.49%. Conclusion: ImageJ can be a valuable tool to quantify biofilm production in glass slides based on the number and percentage area of microcolonies, cell aggregates, and single cells or cell clusters.
Secondary Neoplasm Arising in Nevus Sebaceus of Jadassohn: A Case Report Emphasizing Early Recognition and Evaluation Agung Bima Putera; Asri, Ennesta; Sari, Indah Indria
Scientific Journal Vol. 5 No. 2 (2026): SCIENA Volume V No 2, March 2026
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v5i2.332

Abstract

Background: Nevus sebaceus of Jadassohn (NSJ) is a congenital hamartomatous lesion involving epidermal, sebaceous, and adnexal structures. The lesion typically appears at birth or early childhood and remains stable for years. Secondary neoplastic transformations, either benign or malignant, may occur during adolescence or adulthood. Case: A 15-year-old girl presented with a yellowish plaque on the vertex of her scalp, first noticed at the age of five. Over time, the lesion enlarged, and a bluish-gray nodule developed two weeks prior to presentation, accompanied by localized pain. Dermatological examination revealed a cerebriform yellow-orange plaque with bluish nodules and alopecia. Dermoscopy showed yellow globules, a homogeneous yellow-orange background, and blue-gray ovoid nests. Histopathology confirmed features consistent with NSJ, including epidermal hyperplasia, papillomatosis, sebaceous glands opening into the epidermis, immature hair follicles, and ectopic apocrine glands. In addition, basaloid cell proliferation with peripheral palisading and melanin pigment suggested a secondary neoplasm. The overall findings are consistent with pigmented trichoblastoma, although the possibility of a pigmented basal cell carcinoma cannot be definitively ruled out. Discussion: The findings indicate neoplastic transformation arising within NSJ. Secondary tumors may develop even in adolescence, making early recognition crucial. Clinical changes such as rapid growth, color change, or pain should raise suspicion and prompt histopathological confirmation. Identifying secondary neoplasms influences management decisions, including the need for surgical excision.Conclusion: This case highlights the need for early recognition and thorough evaluation of NSJ lesions, particularly in adolescence, to detect and manage secondary neoplastic changes effectively.
Overlapping Chancre and Syphilitic Roseola in an Immunocompetent Patient: A Case Report Anum, Qaira; Vesri Yossy; Putera, Agung Bima
Scientific Journal Vol. 5 No. 2 (2026): SCIENA Volume V No 2, March 2026
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v5i2.333

Abstract

Background: Syphilis is a sexually transmitted infection caused by Treponema pallidum that typically progresses through primary, secondary, latent, and tertiary stages. Primary syphilis presents with a painless genital chancre, whereas secondary syphilis manifests with systemic and mucocutaneous findings. Overlapping primary and secondary syphilis is uncommon and is rarely reported in immunocompetent individuals.  Case: A 38-year-old immunocompetent man presented with a painless penile ulcer that progressively enlarged over two months, accompanied by non-pruritic erythematous macules with whitish scaling on both palms for one month. Physical examination revealed a solitary, shallow, indurated genital ulcer with well-defined borders and palmar macules. Dermoscopy demonstrated “Biett’s collarette”. Serological testing showed reactive VDRL (1:32) and TPHA (1:5120), with a non-reactive HIV test. Histopathological examination of the penile ulcer revealed epidermal ulceration, dense perivascular plasma cell and lymphohistiocytic infiltration, and endarteritis obliterans, consistent with syphilitic ulcer. Urethral culture identified Neisseria gonorrhoeae, indicating concomitant gonococcal urethritis. The patient was diagnosed with overlapping primary and secondary syphilis with gonorrhea co-infection and was treated with intramuscular benzathine penicillin G, oral cefixime, and azithromycin, resulting in marked clinical improvement.  Discussion: Persistence of the chancre beyond the expected healing period together with concurrent palmar syphilitic roseola supports stage overlap rather than sequential progression. Delayed diagnosis and coexisting gonococcal infection may have contributed to this presentation despite preserved immune status. Conclusion: Overlapping primary and secondary syphilis can occur in immunocompetent patients. Recognition of this atypical presentation and comprehensive clinicopathological correlation are essential to ensure accurate diagnosis and appropriate management.
Hydroxyurea as A Therapeutic Approach in Transfusion-dependent Thalassemia Afriant, Rudy; Transino, Talsi
Scientific Journal Vol. 5 No. 2 (2026): SCIENA Volume V No 2, March 2026
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v5i2.343

Abstract

Major thalassemia, or transfusion-dependent thalassemia (TDT), is a severe form of hemoglobin disorder that requires a lifetime regular blood transfusion. Longterm transfusion leads to iron overload that damaging vital organs and increasing morbidity and mortality. Therefore, alternative therapies are needed to reduce transfusion frequency and its complications. Hydroxyurea (HU) is currently being studied for its potential benefit in TDT. Hydroxyurea is an antimetabolite and antineoplastic agent for sickle cell disease. Hydroxyurea induces the production of fetal hemoglobin (HbF) by stimulating γ-globin expression and inhibiting ribonucleotide reductase, which is essential in DNA synthesis, thereby suppressing ineffective erythropoiesis. This pharmacological effect may increase total hemoglobin levels and reduce transfusion requirements in TDT. Hydroxyurea also improves erythropoiesis, decreases ferritin levels, and enhances red blood cell morphology. Meta-analyses indicate that approximately 25–60% of patients experience at least 50% reduction in transfusion needs, with mild and reversible adverse events. While it is not recognized as standard therapy, current studies support the efficacy and safety of hydroxyurea as an adjunctive therapy for TDT, particularly in resource-limited settings in developing countries. Further studies are needed to confirm its long-term safety profile and to identify the patient populations most likely to benefit from this therapy.
Tuberkulosis Paru Putus Obat pada Diabetes Melitus Tipe 2 Febrianti, Ika Kurnia; Christeven
Scientific Journal Vol. 5 No. 2 (2026): SCIENA Volume V No 2, March 2026
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v5i2.346

Abstract

Latar Belakang: Tuberkulosis (TB) paru masih menjadi masalah kesehatan utama, terutama pada pasien dengan riwayat pengobatan tidak tuntas yang berisiko mengalami kekambuhan dan resistensi obat. Faktor komorbid diabetes melitus tipe 2 (DMT2) akan menyebabkan kuman TB sulit dikendalikan. Laporan Kasus: Seorang laki-laki 57 tahun datang dengan sesak nafas progresif, batuk berdahak kronik, demam hilang timbul, serta penurunan berat badan signifikan. Pasien memiliki riwayat konsumsi OAT lebih dari satu bulan namun berhenti lebih dari dua bulan (loss to follow up). Foto toraks menunjukkan infiltrat lapangan atas–tengah paru, dan Tes Cepat Molekuler (TCM) menunjukkan Mycobacterium tuberculosis (MTB) terdeteksi dengan Rifampicin Resistance Not Detected. Pasien langsung diberikan OAT lini pertama disertai vitamin B6, serta dilakukan Drug Susceptibility Test (DST) yang kemudian mengonfirmasi tidak adanya resistensi obat. Diabetes melitus Tipe 2 yang tidak terkontrol diterapi dengan insulin, dan hiponatremia juga dikoreksi. Kesimpulan: Tuberkulosis paru sensitif obat pada pasien dengan riwayat loss to follow up memberikan respons baik terhadap OAT lini pertama berbasis hasil TCM dan DST. Pendekatan komprehensif dan kepatuhan terapi menjadi kunci keberhasilan pengobatan bersamaan dengan pengontrolan ketat gula darah pada pasien DMT2.
One-Hour Sepsis Bundle Compliance on Serial SOFA Scores and 28-Day Mortality: A Prospective Investigation in Bekasi Regency Referral ICUs Marina S.A, Mega Ayu M; Sugiarto, Adhrie; Soenarto, Ratna Farida; Irfan, Ahmad
Scientific Journal Vol. 5 No. 3 (2026): SCIENA Volume V No 3, May 2026
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v5i3.348

Abstract

Background: Sepsis mortality remains high in intensive care units (ICUs). This study aims to evaluate compliance with the implementation of the One hour sepsis bundle and changes in SOFA scores to predict 28-day mortality rates, knowing the 28-day mortality rate and to identify strong mortality factors mortality in sepsis patients in the ICU two of Type B Hospital, Bekasi Regency. Methods: A prospective observational cohort study was conducted in the ICUs of two Type B hospitals in Bekasi Regency in 2025. Sixty adult sepsis patients with with characteristics, SOFA score, One hour sepsis bundle compliance, Temperature, Respiratory rate (RR), Capillary refill time (CRT), Lactate level examination on admission, 24th hour and 5th day. Data were analysed using bivariate analysis.Results: The 28-day mortality rate was 81.7%. Bundle compliance showed no significant correlation with SOFA score changes or 28-day mortality rates. Bivariate analysis proved that 24-hour and 5-day SOFA, 24-hour and 5-day ΔSOFA, GCS components and renal function in 5-day SOFA scoring were significantly correlated with 28-day mortality rates. Conclusion: Compliance with the One hour sepsis bundle did not significantly affect the 28-day mortality rate. 24-hour and 5-day CRT examinations, 24-hour and 5-day SOFA scoring, 24-hour and 5-day SOFA ∆, day-5 temperature examination, day-5 lactate and Δ lactate levels, SOFA GCS scoring components and renal function can affect the 28-day mortality rate of sepsis patients in the ICU of Type B Hospital, Bekasi Regency.
Assessment of Knowledge and Usage Practices of Retinol-Containing Facial Skincare Products Among Medical Students at Baiturrahmah University Irma Primawati; Olivia Putri; Irdawaty Izrul; Fitra Deny
Scientific Journal Vol. 5 No. 3 (2026): SCIENA Volume V No 3, May 2026
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v5i3.349

Abstract

Background: Retinol, a derivative of vitamin A belonging to the retinoid class, is widely used in facial skincare products due to its efficacy in the management of acne and prevention of premature skin aging. The increasing utilization of retinol among medical students necessitates adequate knowledge and appropriate usage practices to minimize potential adverse effects. Objective: To evaluate the level of knowledge and usage practices of retinol-containing facial skincare products among medical students at Baiturrahmah University. Methods: A descriptive cross-sectional study was conducted involving 64 medical students from the Faculty of Medicine, Baiturrahmah University. Participants were recruited using a consecutive sampling technique. Data were collected through a structured questionnaire and analyzed descriptively. Results: The majority of respondents demonstrated a good level of knowledge regarding retinol. Female students exhibited a higher proportion of good knowledge (67.2%) compared to male students. Based on age distribution, respondents aged 21 years showed the highest level of knowledge (62.5%). Appropriate retinol usage practices were predominantly observed among female students (68.1%) and respondents aged 21 years (70.2%). Conclusion: Medical students at the Faculty of Medicine, Baiturrahmah University generally demonstrate good knowledge and appropriate usage practices regarding retinol, with a predominance among female students and those aged 21 years.

Page 22 of 23 | Total Record : 221

 19   20   21   22   23 

Filter by Year

2022 2026


Reset
Filter By Issues
All Issue Vol. 5 No. 3 (2026): SCIENA Volume V No 3, May 2026 Vol. 5 No. 2 (2026): SCIENA Volume V No 2, March 2026 Vol. 5 No. 1 (2026): SCIENA Volume V No 1, January 2026 Vol. 4 No. 6 (2025): SCIENA Volume IV No 6, November 2025 Vol. 4 No. 5 (2025): SCIENA Volume IV No 5, September 2025 Vol. 4 No. 4 (2025): SCIENA Volume IV No 4, July 2025 Vol. 4 No. 3 (2025): SCIENA Volume IV No 3, May 2025 Vol. 4 No. 2 (2025): SCIENA Volume IV No 2, March 2025 Vol. 4 No. 1 (2025): SCIENA Volume IV No 1, January 2025 Vol. 3 No. 6 (2024): SCIENA Volume III No 6, November 2024 Vol. 3 No. 5 (2024): SCIENA Volume III No 5, September 2024 Vol. 3 No. 4 (2024): SCIENA Volume III No 4, July 2024 Vol. 3 No. 3 (2024): SCIENA Volume III No 3, May 2024 Vol. 3 No. 2 (2024): SCIENA Volume III No 2, March 2024 Vol. 3 No. 1 (2024): SCIENA Volume III No 1, January 2024 Vol. 2 No. 6 (2023): SCIENA Volume II No 6, November 2023 Vol. 2 No. 5 (2023): SCIENA Volume II No 5, September 2023 Vol. 2 No. 4 (2023): SCIENA Volume II No 4, July 2023 Vol. 2 No. 3 (2023): SCIENA Volume II No 3, May 2023 Vol. 2 No. 2 (2023): SCIENA Volume II No 2, Maret 2023 Vol. 2 No. 1 (2023): SCIENA Volume II No 1, January 2023 Vol. 1 No. 6 (2022): SCIENA Volume I No 6, November 2022 Vol. 1 No. 5 (2022): SCIENA Volume I No 5, September 2022 Vol. 1 No. 4 (2022): SCIENA Volume I No 4, July 2022 Vol. 1 No. 3 (2022): SCIENA Volume I No 3, May 2022 Vol. 1 No. 2 (2022): SCIENA Volume I No 2, March 2022 Vol. 1 No. 1 (2022): SCIENA Volume I No 1, January 2022 More Issue