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Journal of Medical Science; Jurnal Ilmu Medis Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh
Published by Rumah Sakit Umum Daerah Zainoel Abidin, Banda Aceh
ISSN : -     EISSN : 27217884     DOI : https://doi.org/10.55572/
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Journal of Medical Science (JMS; Jurnal Ilmu Medis Rumah Sakit Umum Daerah Zainoel Abidin, Banda Aceh) ISSN 2721-7884 diterbitkan oleh Divisi LITBANG Rumah Sakit Umum Daerah Zainoel Abidin, Banda Aceh sejak bulan April 2020. Journal of Medical Science terbit dua kali dalam setahun yaitu pada Bulan April dan Bulan Oktober. JMS adalah jurnal open akses berbasis Open Journal System yang seluruh proses atau tahapan publikasi dilakukan secara online dengan melibatkan mitra bestari (peer-reviewed) dari berbagai topik ilmu bidang medis dan kesehatan. Naskah yang ingin dipublikasikan pada JMS harus merupakan naskah asli hasil penelitian dan juga naskah hasil studi literatur yang memiliki kontribusi dan aplikasi dengan bidang yang berkaitan dengan ilmu medis dan ilmu kesehatan dengan topik sebagai berikut: Ilmu Bedah Ilmu Penyakit Dalam Obstetri dan Ginekologi Ilmu Kesehatan Anak Ilmu Jantung dan Pembuluh Darah Pulmonologi dan Ilmu Kedokteran Respirasi Neurologi Ilmu Kesehatan THTKL Ilmu Kesehatan Mata Ilmu Kesehatan Kulit dan Kelamin Anestesiologi dan Terapi Intensif Ilmu Kedokteran Forensik dan Medikolegal Ilmu Kedokteran Fisik dan Rehabilitasi Radiologi Mikrobiologi Ilmu Kesehatan Gigi dan Mulut Patologi Klinik Patologi Anatomi Gizi Klinik Ilmu Kedokteran Jiwa
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 100 Documents
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Pengaruh Pemberian Platelet-Rich Plasma Terhadap Derajat Keparahan Psoriasis Vulgaris Nanda Earlia; Cut Yunita; Mikyal Bulqiah; Aqil Yuniawan Tasrif; Karamina Maghfirah
Journal of Medical Science Vol 3 No 2 (2022): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v3i2.79

Abstract

Psoriasis vulgaris is an autoimmune disease that is influenced by multifactor, namely environmental, genetic (HLA-Cw6), and immune system dysregulation (IL-17 or IL-22), resulting in increased proliferation of keratinosit in the epidermis. Histologically characterized by parakeratosis, hyperkeratosis, elongated rete ridge, Monro micro abscess, and Kogoj micro abscess. The clinical picture is red patches with thick scales, especially in the trauma area. Platelet Rich Plasma (PRP) is an autologous preparation of platelets that strengthens in plasma and is a powerful anti-inflammatory agent. The immunomodulatory and anti-inflammatory effects of PRP are believed to play a role in the treatment of chronic inflammation patients. One of the important mediators in the pathogenesis of psoriasis is nuclear factor kappa B (NF-κB) and PRP exerting an inhibitory effect on NF-κB. The aim of the study was to assess the effect of PRP on the severity and quality of life of psoriasis vulgaris patients. The design of this study is a paired numerical comparative analysis using two groups with two measurements. The research design was a randomized, undisguised clinical trial and a parallel design. The study lasted for 6 weeks. Sampling was done by total sampling involving 20 psoriasis Vulgaris patients, then divided into two groups: intervention group and control group. The test group received 2 PRP injections and topical combination therapy (salicylic acid 3% + Vaseline album cream), while the control group only received topical combination therapy. The results of this study found a decrease in PASI and DLQI scores in the intervention group compared to the control group (p<0.005). This study concludes that the administration of PRP can reduce the severity of psoriasis Vulgaris as well as improve the quality of life of psoriasis Vulgaris patients.
Pengaruh Diuretik Terhadap Stone-Free Rate Batu Ureter dengan Pneumatic Lithotripsy Jufriady Ismy; Muhammad Ridha; Dahril; Rayyan Al Faruqi; Muyasir
Journal of Medical Science Vol 3 No 2 (2022): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v3i2.82

Abstract

Pneumatic Lithotripsy (PL) is considered effective in fragmenting hard stones, and this procedure can also be performed transurethrally and percutaneously on large stones. This study aimed to see the percentage of Stone Free Rate (SFR) by administering force diuretics to ureteral stones that were crushed using PL. Previous studies have found that intravenous loop diuretic administration is effective, safe, and efficient in obtaining a much higher percentage of SFR and can reduce the average number of sessions per stone during extracorporeal shock wave lithotripsy (ESWL). We identified study subjects from early July-September 2022 and obtained as many as 38 study subjects (SP) with stones in the distal ureter <20mm. Subjects were randomly selected and divided into two groups: the group given diuretics (K2) and not given (K1). With a 90% confidence degree and 15% sampling error, based on Lameshow's formula, 30 SP can be observed; eight other subjects were excluded because they experienced a decrease in systolic pressure >25% (5 SP) and the remaining stones came out without splitting (3SP). The results obtained were SFR levels that were statistically significant (p<0.05) and clinically using the Mann-Whitney statistical test. Administration of diuretics to patients with distal ureteral stones undergoing URS with Pneumatic Lithotripsy is safe and effective as an anti-retropulsion method. It is the strategy of choice in centers that do not provide laser lithotripsy or flexible ureteroscope.
Keberhasilan Tatalaksana Infeksi Virus Hepatitis C di Rumah Sakit Umum Daerah dr. Zainoel Abidin Banda Aceh dr. Azzaki Abubakar, Sp.PD-KGEH; dr. Andrie Gunawan, SpPD; Julia Sari
Journal of Medical Science Vol 3 No 2 (2022): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v3i2.87

Abstract

Hepatitis C is a world health problem with a high mortality rate. The Indonesian Ministry of Health has been controlling hepatitis C infection since 2017 using Direct Acting Antiviral (DAA) drugs which have lower side effects and a higher cure rate. This study aims to determine incidence, patient demographic data, and liver fibrosis scores on the successful treatment of hepatitis C infection at RSUD dr. Zainoel Abidin Hospital. Inclusion criteria in this retrospective cohort design was patients with positive anti hepatitis C virus (Anti-HCV). Treatment was carried out when the viral load was detected by giving Sofosbuvir 400 mg per day and Daclatasvir 60 mg per day for 12 weeks, then patient returns to be examined to assess the successful therapy. Thirty eight out of 5002 patients (0.76%) showed positive Anti-HCV, most patients aged over 60 years (39.47%), was dominated by male (55.26%), and most of them are located in Banda Aceh (47 ,36 %). Thirty out of 38 positive anti-HCV patients (78.95%) had HCV RNA, but 15 patients (50%) were not eligible for treatment. Seven out of 15 patients (46.7%) completed DAA treatment. All HCV RNA were undetectable, improved AST values ​​and decreased aspartate aminotransferase-platelet ratio index (APRI) scores which showed improvement in liver fibrosis, after completing therapy. Hepatitis C patients who adhere to treatment and management of hepatitis C will get good results marked by improvement in liver fibrosis and undetectable HCV RNA.
Analisis Komplikasi Infeksi Terkait Tindakan Blok Epidural pada Pasien Pasca Operasi Di RSUD Dr. Zainoel Abidin Banda Aceh Zafrullah Khany Jasa; Yusmalinda; Hafizh Arief
Journal of Medical Science Vol 3 No 2 (2022): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v3i2.88

Abstract

Neuraxial block-associated infection is a rare complication, this could be due to better aseptic technique and possibility of unreported events. There are four mechanisms by which microorganisms enter the body during insertion of an epidural catheter, include inoculation of microorganisms on the skin surface, pathways along the insertion of epidural catheter, contamination of local anesthetic drugs, and hematogenous spread. The aim of the study is to find out incidence of infectious complications and risk factors for infection in patients who had an epidural catheter inserted in dr. Zainoel Abidin hospital Banda Aceh. A cross-sectional study was conducted over 3 months period with 45 total sampling patients who received epidural blocks. Analysis was done to know relationship beetwen age, number of attempts at insertion of epidural needles, duration of catheter in situ, comorbid DM, malignancy, duration of postoperative bed rest, and blood leukocyte count, signs of inflammation, neurological deficits, and bacterial culture of the epidural catheter. No infection was found, however there were 14 positive epidural catheter culture obtained Gram-negative rods. Nine of the 14 positive culture samples were patients with malignancy. All patients with positive culture samples had bed rest ≥2 days (p=0.004). No asociation between dependent and independent variables in this study (p>0.05). Positive culture results cannot be defined as an infection, however colonization at epidural catheter tip is an early sign of an imminent infectious process.
Analisis Faktor-Faktor yang Mempengaruhi Gangguan Perilaku dan Fungsi Kognitif di Masa Pandemi COVID-19 Pada Pasien Poliklinik Neurologi RSUD dr. Zainoel Abidin Ika Marlia; Suherman; Fitria Armalivia
Journal of Medical Science Vol 3 No 2 (2022): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v3i2.96

Abstract

COVID-19 pandemic is an extraordinary issue and attacks almost the entire world population. Mental health problems such as behavioral disorders and cognitive disorders that arise as a result of the pandemic can develop into health problems that can last long time and potential to cause heavy social burden. This study aims to analyze factors that influence behavioral and cognitive function disorders during COVID-19 pandemic in patients at Neurology Outpatient Clinic RSUD dr. Zainoel Abidin. This study used a descriptive-analytic research method with a cross-sectional design. Bivariate data were analyzed using t-test. Totaled participants during July−September 2022 was 122 respondents, consisting of males (n=68) and females (n=54). Based on Moca Ina score’s result, respondents aged <40 years (14.8%), higher education level (24.6%), had no history of chronic disease ( 25.4%), and have coping skills (27%) showing normal cognitive function. Based on Abe's BPSD score’s result, higher education level (26.2%) and coping abilities (24.6%) show normal behavior. Age, level of education, history of chronic disease, and coping abilities are associated with impaired cognitive function, while educational level and coping abilities are associated with behavioral disorders.
Hubungan Lama Pengobatan Dan Jenis Obat Antiepilepsi Dengan Efek Samping Obat Pada Pasien Epilepsi Di Poliklinik Neurologi RSUDZA Nova Dian Lestari; Sri Hastuti; Nur Astini
Journal of Medical Science Vol 3 No 2 (2022): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v3i2.98

Abstract

Epilepsy is one of the most common neurological diseases that can affect people of all ages, races, social classes, and geographic locations. Epilepsy is caused by abnormal release of neurons in the brain characterized by seizures. Data from the World Health Organization shows that epilepsy accounts for a significant proportion of the world's disease burden, affecting nearly 50 million people worldwide. The goal of management of epilepsy patients is to control seizures and improve quality of life. However, the side effects of antiepileptic drugs can significantly impair quality of life. This study aims to determine the relationship between duration of treatment and types of antiepileptic drugs with side effects of drugs in epilepsy patients at RSUDZA Neurology outpatient clinic. This is an observational analytic study with a cross sectional design. The sample of this study was epileptic patients at RSUDZA Neurology Outpatient Clinic based on inclusion and exclusion criteria with a total of 42 samples. Sampling was carried out from May−September 2022 using a consecutive sampling technique and filling out the Liverpool Adverse Effect Profile (LAEP) questionnaire. Existing research sample data were tabulated and analyzed by univariate analysis to present the frequency and percentage. Spearman's correlation statistical test was used to test the relationship between variables.  The patients consisting of 17 men (40.5%) and 25 women (59.5%). The average length of treatment that respondents had undergone was 52 months, all of whom experienced side effects of antiepileptic drugs. The results of the Spearman's correlation statistical test showed that there was no relationship between the length of treatment and the type of antiepileptic drug with drug side effects in patients diagnosed with epilepsy at RSUDZA Neurology Outpatient Clinic.
Penggunaan Minyak Kayu Putih untuk Membersihkan Sisa Perekat Plester pada Kulit Pasien di Ruang Rawat Inap RSUD dr.Zainoel Abidin Tri Nur Handayani; Cut Nurfazmiati; Suriati
Journal of Medical Science Vol 4 No 1 (2023): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v4i1.72

Abstract

Penggunaan plester bisa menyebabkan sisa perekat plester menempel dan tinggal di kulit yang dapat membuat perubahan performance kulit pasien, dan bagi umat muslim hal tersebut akan menghalangi air wudhu mengenai kulit. Penelitian ini merupakan penelitian kuasi eksperimen yang bertujuan untuk membuktikan secara ilmiah penggunaan minyak kayu putih dalam membersihkan sisa perekat plester yang menempel pada kulit pasien. Untuk itu dilakukan evaluasi lama waktu pembersihan sisa perekat plester menggunakan 2 jenis bahan yaitu minyak kayu putih, dan alkohol swab, selanjutnya dilakukan perbandingan antara kedua jenis bahan tersebut. Sampel penelitian berjumlah 60 pasien, terdiri atas 30 responden kelompok intervensi (minyak kayu putih) dan 30 responden kelompok kontrol (alkohol swab). Hasil penelitian menunjukkan rata-rata lama waktu pembersihan sisa perekat plester dengan minyak kayu putih 16,9117 detik, sedangkan dengan alkohol swab 25,4610 detik. Hasil uji Mann Whitney diperoleh p value 0,039, terdapat perbedaan lama waktu pembersihan sisa perekat plester antara minyak kayu putih dan alkohol swab dengan rerata selisih waktu 8,55 detik. Berdasarkan hal tersebut maka minyak kayu putih dapat direkomendasi sebagai bahan alternatif membersihkan sisa perekat plester yang melekat pada kulit pasien.
Analisis Kelembapan Kulit pada Pasien Anak dengan Penyakit Jantung Bawaan Di RSUDZA Banda Aceh Vella; Herlina Dimiati; Elfa Wirdani Fitri
Journal of Medical Science Vol 4 No 1 (2023): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v4i1.73

Abstract

Kulit adalah organ terbesar dalam tubuh manusia dan bertindak sebagai pertahanan tubuh terhadap agen eksternal seperti mikroorganisme, radiasi UV, dan rangsangan fisik dan kimia. Salah satu parameter yang paling sering digunakan dalam menilai fungsi sawar kulit, baik pada kulit sehat maupun pada penyakit tertentu, adalah dengan melakukan penilaian kelembapan ataupun hidrasi kulit dengan menggunakan trans-epidermal water loss (TEWL) dan skin capacitance (Scap). Terdapat berbagai penyakit yang disertai gangguan kelembapan kulit seperti dermatitis atopik, psoriasis, penyakit metabolik lainnya seperti ginjal, diabetes melitus hingga penyakit jantung. Tujuan penelitian ini adalah untuk menganalisis kelembapan kulit pada pasien anak dengan penyakit jantung bawaan (PJB) di RSUDZA Banda Aceh. Penelitian ini merupakan penelitian analitik observasional dengan desain cross sectional yang dilakukan pada 37 pasien anak dengan PJB yang berobat pada poliklinik jantung anak RSUDZA Banda Aceh serta memenuhi kriteria inklusi dan ekslusi dengan metode total sampling dalam kurun waktu 3 bulan.  Status kelembapan kulit di area dahi, pipi, leher, ekstremitas atas dan bawah dinilai dengan menggunakan alat Tewameter dan Corneometer yang dianalisis menggunakan uji T tidak berpasangan. Hasil penelitian menunjukkan bahwa dari 37 sampel, 72.9% merupakan PJB tipe non-sianotik, dimana jenis kelamin terbanyak pada kelompok PJB sianotik adalah laki-laki (70%) sedangkan kelompok non-sianotik yang terbanyak adalah perempuan (51.9%). Kedua kelompok didominasi oleh anak usia 1 sampai 5 tahun (PJB sianotik, 70%; PJB non-sianotik 70.4%) dengan berat badan lahir ≥ 2500 gr (PJB sianotik, 60%; PJB non-sianotik 74.1%). Nilai TEWL kelompok PJB sianotik lebih tinggi dibandingkan kelompok non-sianotik dan nilai Scap kelompok PJB sianotik lebih rendah dibandingkan kelompok non-sianotik sehingga dapat disimpulkan pasien anak dengan PJB sianotik memiliki kelembapan kulit yang lebih buruk dibandingkan anak dengan PJB non sianotik (p<0.05).
Pengaruh Terapi Qur'anic Healing dengan Glasgow Coma Scale dan Vital Sign pada Pasien Penurunan Kesadaran di RSUD dr. Zainoel Abidin Fithriany; Sabrizal Ishak; Rima Novita Sari; Nasaie; Firly Ratsmita; Nazriati
Journal of Medical Science Vol 4 No 1 (2023): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v4i1.74

Abstract

Qur’anic healing merupakan sebuah teknik terapi penyembuhan dengan cara membacakan ayat-ayat Al-Quran yang mu’tabaroh kepada pasien sesuai  ketentuan Al-Quran dan As-Sunnah sebagaimana dicontohkan pada masa Rasulullah SAW.Penurunan kesadaran merupakan kondisi dimana otak mengalami defisiensi fungsi yang disebabkan oleh berbagai macam penyakit seperti stroke, diabetes melitus, trauma, sepsis dan lain-lain. Penelitian ini dilakukan diruang  High Care Unit Medical RSUDZA dengan responden pasien yang mengalami penurunan kesadaran akibat sepsis. Penelitian ini bertujuan untuk mengetahui pengaruh terapi qur’anic healing dalam mempengaruhi outcome pasien dengan penurunan kesadaran akibat sepsis menggunakanGlasgow Coma Scale(GCS) dan Vital Sign. Metode penelitianQuasi Experimentaldengan two grup pre-post test design dan teknik pengambilan sampel consecutive sampling dengan subjek penelitian sesuai kriteria inklusi dan eklusi. Subjek penelitian sebanyak 24 responden dibagi dua kelompok perlakuan. Kelompok satu 12 reponden mendapatkan perlakuan terapi qur’anic healing dilakukan langsung oleh ustadz/ah, kelompok dua 12 reponden mendapatkan perlakuan terapi qur’anic healing dengan cara memperdengarkan audio. Hasil analisis uji-T yang membandingkan perubahan GCS dari dua metode perlakuan secara langsung atau memperdengarkan audio menunjukkan p-value= 0,001 (≤0,05). Dapat disimpulkan bahwa perbedaan GCS metode langsung dan audio adalah nyata. Sedangkan Uji mann whitney membandingkan perubahan vital sign dari dua metode perlakuan, menunjukkan ada pengaruh metode terhadap perubahan vital sign. Hasil uji mann whitneyberturut turut systole, diastole, nadi, respirasi, dan suhu=0.317, 0.317, 1.00, 1.00, 0.546 yang semuanya > dari 0.05 maka perbedaan vital sign metode langsung dan audio adalah tidak nyata. Walaupun tidak nyata ada kecenderungan vital sign dari metode langsung lebih baik dibandingkan metode audio di setiap aspek yang diamati kecuali di aspek nadi yang perubahan keduanya sama. Kesimpulan pada penelitian ini adalah terapi qur’anic healing berpengaruh terhadap kestabilan vital sign sertapeningkatan GCS pada pasien yang mengalami penurunan kesadaran.
Hubungan Derajat Keparahan Area Vitiligo dengan Tingkat Depresi pada Pasien Vitiligo di Poliklinik Kulit dan Kelamin Rumah Sakit Umum Daerah dr. Zainoel Abidin Banda Aceh Arie Hidayati; Mimi Maulida; Nanda Earlia; Mahda Rizki Liana
Journal of Medical Science Vol 4 No 1 (2023): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v4i1.75

Abstract

Vitiligo menimbulkan perbedaan jelas antara kulit depigmentasi dan kulit normal yang menyebabkan pasien vitiligo sering menghadapi stigmatisasi dan masalah psikososial sehingga rentan terhadap depresi, kecemasan, dan stres. Tujuan penelitian ini adalah untuk mengetahui hubungan antara derajat keparahan vitiligo dengan tingkat depresi pasien vitiligo. Penelitian ini merupakan penelitian analitik observasional dengan desain cross-sectional. Pengumpulan data menggunakan teknik consecutive sampling dan pengisian kuesioner Back Depression Scale pada Juli hingga Oktober 2022 di Poliklinik Kulit dan Kelamin Rumah Sakit Umum Daerah dr.Zainoel Abidin Banda Aceh. Kriteria inklusi meliputi pasien dengan diagnosis vitiligo, usia 13-80 tahun, dan bersedia mengikuti penelitian; sedangkan kriteria eksklusi adalah pasien vitiligo yang telah didiagnosa dengan depresi, dan telah atau dalam proses pengobatan depresi.  Didapatkan hasil dari 31 sampel sebanyak 48,4% laki-laki, 51,6% perempuan, usia rata-rata 36 tahun, 32,4% merupakan siswa dan mahasiswa, guru/dosen dan PNS masing-masing 12,9%.  Jenis klinis vitiligo localized sebesar 58,1 %, vulgaris 29%, dan acrofacial 12,9%. Sebanyak 74,2% telah mengalami vitiligo selama 1-5 tahun, 54,6% telah mendapatkan pengobatan selama 1-5 tahun; 64,5% dengan riwayat pengobatan topikal dan fototerapi.  Mayoritas (93,5%) pasien vitiligo tidak memiliki riwayat autoimun lainnya, 87,1% memiliki tingkat keparahan vitiligo ringan, 6,5% vitiligo sedang, dan 6,5% vitiligo berat. Sebagian besar pasien (93,5%) tidak mengalami depresi, dan 6,5% menderita depresi ringan. Berdasarkan analisa bivariat didapatkan hubungan yang lemah antara derajat keparahan vitiligo dengan tingkat depresi (p= 0.66), sehingga disimpulkan bahwa tidak terdapat hubungan antara derajat keparahan vitiligo dengan terjadinya depresi.

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