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Asian Journal of Health Research
Published by Ikatan Dokter Indonesia Wilayah Jawa Timur
ISSN : 28292979     EISSN : 28289269     DOI : https://doi.org/10.55561/ajhr
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Asian Journal of Health Research (AJHR) is an open access journal published by Ikatan Dokter Indonesia Wilayah Jawa Timur and launched in 2022. This journal is peer reviewed publishing to communicate high quality research, general articles, and all fundamental research/ clinical studies relevant to health science. The journal publishes articles Medical Sciences scope including (Obstetrics and Gynaecology, Pediatrics, Internal medicine, Ophthalmology, Surgery, Neurology, Otolaryngology, Cardiology and Vascular Medicine, Anaesthesiology and Reanimation, Dermatovenerology, Orthopaedics and Traumatology, Urology, neurosurgery, Cardiothoracic surgery, Orthopaedics and Traumatology, Plastic Reconstructive Surgery and Aesthetics, Pulmonology and Respiratory Medicine, Forensic Medicine, and Medicolegal, Psychiatry Medicine and Rehabilitation). AJHR journal is published three times per year in April, August, and December.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 160 Documents
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Genital Tuberculosis with Pleuritis and Intra-abdominal Tuberculosis Widowati, Ayu Rizky; Indrawan, I Wayan Agung; Tantular, Rezki
Asian Journal of Health Research Vol. 4 No. 2 (2025): Volume 4 No 2 (August) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i2.247

Abstract

Introduction: Female Genital Tuberculosis (FGTB) is a rare but serious form of extrapulmonary tuberculosis that significantly impacts female reproductive health. It accounts for 15–20% of extrapulmonary TB cases and is found in 5–10% of infertile women. Diagnosis is often delayed due to nonspecific symptoms and the difficulty of confirming infection through histopathology. Case Presentation: A 35-year-old woman presented with abdominal pain, nausea, vomiting, vaginal discharge, and postcoital bleeding. A cervical biopsy confirmed tuberculous cervicitis, supported by systemic TB symptoms and a left pleural effusion, leading to a diagnosis of extrapulmonary TB. She was treated with a full course of anti-TB therapy and referred for fertility evaluation due to persistent amenorrhea, where hysteroscopy revealed intrauterine adhesions and granulomas, confirming suspected genital TB and suggesting Asherman’s syndrome as a complication. Conclusion: Female Genital Tuberculosis is a rare cause of infertility; early diagnosis using integrative methods and awareness of genital TB transmission are essential for timely treatment and improved reproductive outcomes.
Sexual Health Knowledge among Malaysian with Coronary Artery Disease Mansor, Wan Mazrizman Wan; Engkasan, Julia Patrick
Asian Journal of Health Research Vol. 4 No. 2 (2025): Volume 4 No 2 (August) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i2.249

Abstract

Introduction: Sexual counselling is a fundamental aspect of cardiac rehabilitation. It is challenging to develop an appropriate framework for sexual counselling in coronary artery disease patients without having knowledge about their level of sexual knowledge. Material and Methods: A descriptive, correlational cross-sectional study was conducted at the Cardiac Rehabilitation Clinic Universiti Malaya Medical Centre, Kuala Lumpur. A convenience sample of 112 patients diagnosed with myocardial infarction or coronary artery disease was recruited. The patient’s sexual health knowledge was assessed using the Sex After Myocardial Infarction Knowledge Test. Results: The majority of patients were male (85%), mean age of 57±11 years, Malay (46%), had secondary education (54%), married for 27±13 years and was diagnosed within 4±5 years. Questions on awareness of cardiac symptoms and safety during sexual activity scored the highest, while questions on medication safety, suitable time for sex, and partner communication scored the lowest. No statistically significant relationships found between the level of knowledge and age, sex, religion, education level, employment status, number of years of marriage, or duration of the diagnosis. Most of were interested in talking about sexual health but rarely had the opportunity to discuss. Conclusion: Sexual health is an important concern for patients with coronary artery disease. Some patients are symptomatic and have difficulty having sex. This study identifies specific issues that need to be addressed, especially convenient time, medication safety, and effective communication when providing sexual education.
Association between Vitamin D 1,25 (OH)2 D3 Serum with Endometriosis-Related Pelvic Pain and Infertility Condition in Endometriosis Wiyasa, I Wayan Arsana; Suseno, Daniel Alexander; Suwana, Febie Putra
Asian Journal of Health Research Vol. 4 No. 2 (2025): Volume 4 No 2 (August) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i2.253

Abstract

Introduction: Endometriosis is an estrogen-dependent chronic inflammatory disease characterized by the growth of endometrial tissues outside the endometrium or in the pelvic area. This condition is usually found in reproductive women, 15 – 49 years old. Chronic pelvic pain related to endometriosis is one of the major symptoms that makes women come to the clinic, besides dysmenorrhea and dyspareunia. This condition also affects the fertility of women, which, in some reports, shows that 30 – 50% women with endometriosis are also infertile. Vitamin D is a type of vitamin that is popular for treating reproductive problems. Vitamin D (1,25 (OH)2 D3) serum is important in inflammation and implantation, which supports overcoming endometriosis symptoms. Material and Methods: The Present study performed a cross-sectional study. A total of ninety-one women were included in this study, which was divided into three groups: normal group, the pelvic pain group, and the infertility pain. In this study, from ANOVA and confirmed with LSD 95% test. Results: There is a difference in Vitamin D (1,25 (OH)2 D3) serum level in the chronic pelvic pain group and/or infertility group. This significantly shows that there is a correlation between those variables. Conclusion: Sexual health is an important concern for patients with coronary artery disease. Some patients are symptomatic and have difficulty having sex. This study identifies specific issues that need to be addressed, especially convenient time, medication safety, and effective communication when providing sexual education.
Profile of Cerebral Arteriovenous Malformations at Dr. Saiful Anwar Hospital Malang: A Multi-Modality Epidemiologic Study Setyawan, Agung; Imron, Fatkhul Ali
Asian Journal of Health Research Vol. 4 No. 2 (2025): Volume 4 No 2 (August) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i2.255

Abstract

Introduction: Brain arteriovenous malformations (AVMs) are congenital abnormalities in which direct connections form between arteries and veins, bypassing the capillary network and resulting in significant hemodynamic disturbances. This abnormal vascular architecture increases the risk of life-threatening intracranial hemorrhage. The diagnosis and management of brain AVMs are challenging due to their variability in size, location, and vascular supply. Accurate assessment requires advanced imaging modalities such as CT, MRI, and DSA, combined with the Spetzler-Martin (S-M) classification for risk stratification. Epidemiological studies are important for guiding clinical decisions. This study aims to describe the demographic, clinical characteristics, and imaging findings of brain AVMs patients at Dr. Saiful Anwar Hospital, Malang. Material and Methods: A retrospective descriptive study using radiology records from September 2020 to August 2024, including all patients diagnosed with brain AVMs who underwent CT, MRI, or DSA imaging. Results: The majority of patients were male (69.6%), and the largest age group was ≥50 years (36.9%). The most common presenting symptom was neurological deficit (47.8%), followed by headache (30.4%) and seizure (21.8%). S-M grading varied by imaging modality, CT most frequently detected grade III, MRI identified grades III–V, while DSA most often revealed grade I. Conclusion: Cerebral AVMs are more commonly treated in males and individuals aged ≥50 years. The main symptoms are neurological deficits, headaches, and seizures. A multimodal approach is essential for diagnosis and management.
L-Citrulline Supplementation in Postmenopausal Women: Evidence from Clinical Trials Panggabean, Satya Alfarisma; Mumtazah, Intan Syarifatin; Arifianti, Laily Nur Rachmah Wati Putri; Muhammad, Rajasawardana Fadhli
Asian Journal of Health Research Vol. 4 No. 2 (2025): Volume 4 No 2 (August) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i2.256

Abstract

Introduction: Postmenopausal women are at heightened risk for cardiovascular and muscular health decline due to endothelial dysfunction, arterial stiffness, and reduced nitric oxide (NO) bioavailability. L-Citrulline, a precursor to L-arginine and NO, has emerged as a promising supplement to counter these age-related vascular and musculoskeletal impairments.    Material and Methods: A systematic review of randomized controlled trials was conducted in accordance with PRISMA guidelines using PubMed, ScienceDirect, and Cochrane Library databases. Eligible studies assessed oral L-Citrulline supplementation in postmenopausal women, with outcomes categorized into: vascular function (blood pressure, flow-mediated dilation [FMD], pulse wave velocity [PWV]); muscle function and oxygenation (tissue saturation index [TSI], oxy-/deoxyhemoglobin [O₂Hb/HHb], strength, lean mass, exercise performance); and autonomic regulation (heart rate variability [HRV]). Methodological quality was evaluated using the Cochrane Risk of Bias Tool 2.0.    Results: L-Citrulline supplementation, administered in doses ranging from 6 to 10 g/day over 4–8 weeks, significantly improved cardiovascular outcomes, including reductions in brachial and aortic systolic/diastolic blood pressure, pulse pressure, and augmentation index. Flow-mediated dilation (FMD) improved by up to 2.7%, and nitric oxide availability increased, indicating enhanced endothelial function. Additionally, L-Citrulline improved muscle oxygenation during exercise, increased leg lean mass and strength when combined with low-intensity resistance training, and favorably modulated autonomic function through improved heart rate variability.    Conclusion: L-Citrulline supplementation demonstrates substantial potential for improving vascular health, enhancing muscle oxygenation and strength, and restoring autonomic balance in postmenopausal women. These findings support its use as a non-pharmacological strategy to mitigate age-related declines in cardiovascular and muscular function.
Columellar Lengthening on Corrected Cleft Lip and Palate (La---aL) Post Cheilorrhaphy: A Case Report Zeeva, Evane Jovanie; Norholila; Santoso, Clara Cindy Ateng; Effendi, Muchiddin Andri Setyo; Medina, Nadra Odifa; Adiwinoto, Ronald Pratama; Prameswari, Renata
Asian Journal of Health Research Vol. 4 No. 2 (2025): Volume 4 No 2 (August) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i2.259

Abstract

Introduction: The Cleft Lip and Palate (CLP) is a congenital malformation involving the orofacial region. The failure of frontonasal and maxillary processes to fuse causes a gap through the lips, alveoli, base of the nose, and in the hard and/or soft palate. Case Presentation: This case report illustrates a 2-year-3-month-old female patient diagnosed with bilateral cleft lip and palate at birth. The patient underwent cheilorrhaphy at 4 months old and currently plans to have scar revision and columellar lengthening surgery at Dr. Ramelan Naval Hospital, Surabaya. The patient presents with a flat nose, a hypertrophic scar above the lip, and speech articulation impairment. Her medical history includes prenatal maternal hypertension, neonatal pneumonia, and exposure to cigar smoke. Additionally, there is a family history of cleft lip and palate. This case highlights the vital role of columellar lengthening in enhancing nasal appearance and airway patency for optimal outcomes without complications. Conclusion: Cleft lip and palate (CLP) require multidisciplinary care. Columellar lengthening and scar revision have been proven effective in enhancing nasal functions and aesthetics. The presence of prenatal maternal hypertension, exposure to cigar smoke, and familial history of CLP accentuates etiological complexity. The case shows successful intervention balancing function, aesthetics, and craniofacial growth in CLP repair. This study aims to increase insight for future management concerning nasal deformities in CLP patients.
D4P4: A Neuro-Pedagogic Model for Developing High-Risk/ High-Precision Procedural Skills in Residency Training Hermanto TJ
Asian Journal of Health Research Vol. 4 No. 2 (2025): Volume 4 No 2 (August) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i2.274

Abstract

Medical education stands at a pivotal juncture. The long-standing "see one, do one, teach one" model, once the cornerstone of clinical training, is increasingly inadequate for preparing today’s physicians. Rising resident-to-patient ratios, overwhelmed faculty, and the distinct learning preferences of Generation Z demand a more sophisticated and responsive approach. In response to these challenges, the D4P4 model emerges as a transformative framework—rooted in decades of neuroscience and educational theory—designed to cultivate high-risk, high-precision procedural skills in residency programs..
Do Medicine and Medical Education Need a Paradigm Shift? Hermanto TJ
Asian Journal of Health Research Vol. 4 No. 3 (2025): Volume 4 No 3 (December) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i3.300

Abstract

Modern medicine stands at a crossroads. The Human Genome Project and the Decade of the Brain have revealed the profound biological and neurological individuality of every human being. Yet paradoxically, clinical practice and medical education continue to operate as if one method fits all. Patients are often reduced to diagnostic codes and treatment algorithms, while students are molded through standardized curricula, uniform assessments, and teacher-centered instruction. The result is a dissonance between what science now knows, that every brain and body is unique, and how medicine is still practiced and taught. Half a century ago, Ivan Illich, in Medical Nemesis, warned of the medicalization of life where health becomes a commodity and suffering a pathology. Today, his warning resounds in the rising prevalence of iatrogenic conditions, from overtreatment to complex disorders such as placenta accreta syndrome. Bernard Lown in The Lost Art of Healing, lamented the erosion of empathy, while Atul Gawande’s Being Mortal reminds us that extending life is not the same as healing it. These critiques echo Sir William Osler’s timeless insight: that the good physician treats the disease, but the great physician treats the patient who has the disease.
Neoadjuvant Chemotherapy Before Radical Hysterectomy in Cervical Cancer: A Systematic Comparison of Robotic vs Abdominal Approaches Wahyuni, Rizki; Irwanto, Yahya
Asian Journal of Health Research Vol. 4 No. 3 (2025): Volume 4 No 3 (December) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i3.248

Abstract

Introduction: Cervical cancer remains a leading cause of cancer mortality worldwide. Neoadjuvant chemotherapy (NACT) followed by radical hysterectomy (RH) is increasingly used, but the comparative safety and efficacy of robotic‐assisted versus open abdominal RH after NACT remain unclear.    Material and Methods: This PRISMA‐compliant systematic review (January 2015–March 2025) analyzed randomized and observational studies comparing robotic‐assisted RH (RRH) and open RH (ARH) in women with FIGO IB₂–IIA₂ cervical cancer treated with platinum‐based NACT. The primary endpoints were intraoperative and postoperative complications. Seven studies involving 534 patients (284 minimally invasive vs. 250 open) met the inclusion criteria.    Results: Overall complication rates were similar between groups (15–20%). Minimally invasive surgery (MIS) significantly reduced estimated blood loss by 75–315 mL (p<0.05) and shortened hospital stay by 1–2 days (p<0.01). Operative time was comparable, with minor increases in conventional laparoscopy. In nerve‐sparing procedures, MIS provided faster bladder and bowel recovery (post‐void residual normalization 11 vs. 18 days; time to flatus 39 vs. 56 hours; p<0.01) and improved 1‐year urinary and intestinal quality of life.    Conclusion: Six of seven studies found no difference in disease‐free or overall survival between MIS and open RH. One study reported worse outcomes with RRH among patients with FIGO IIB disease and multi‐agent NACT (HR 2.5–3.0; p<0.05), suggesting risk in higher‐stage, heavily pretreated cases. Overall, robotic‐assisted RH appears to be a safe and effective alternative to open surgery for appropriately selected FIGO IB₂–IIA₂ cervical cancer patients after NACT.
The Effect of Red Bean Extract (Phaseolus vulgaris L. sp) on Systemic Lupus Erythematosus (SLE) from Obstetrics and Gynecology Perspective: A Systematic Review Nooryanto, Mukhamad; Dewi, Chynthea Paramitha
Asian Journal of Health Research Vol. 4 No. 3 (2025): Volume 4 No 3 (December) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i3.254

Abstract

Introduction: Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease predominantly affecting women of reproductive age, with significant morbidity and mortality. Emerging evidence suggests that diet may modulate disease activity, and red bean (Phaseolus vulgaris L.), rich in bioactive compounds, exhibits potential anti-inflammatory and antioxidant effects.    Material and Methods: A systematic literature review was performed using MeSH terms and relevant keywords related to SLE and red bean extract (Phaseolus vulgaris L.), with searches conducted across PubMed, Scopus, ScienceDirect, ResearchGate, and Google Scholar for studies published between 2013 and November 2023, followed by structured title, abstract, and full-text screening based on predefined criteria.    Results: A total of 696 records were initially identified, of which 423 duplicates were removed. After title and abstract screening, 210 articles were assessed, and 21 full-text articles were reviewed. Eleven studies were excluded due to irrelevant outcomes, inappropriate study design, or language restrictions. Ten studies were included in the qualitative synthesis. The findings suggest that bioactive components of red beans may contribute to reduced inflammatory responses and improved clinical manifestations of SLE. Dietary interventions involving red bean consumption demonstrated potential benefits, particularly for women with SLE who are planning pregnancy.    Conclusion: Nutritional therapy may serve as an effective adjunct in the management of SLE, with red bean–based dietary interventions showing potential to reduce disease activity. Nonetheless, robust experimental and clinical studies are essential to validate their efficacy and inform evidence-based clinical recommendations.

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