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Contact Name
Arman Harahap
Contact Email
armanhrahap82@gmail.com
Phone
+6285370005518
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armanhrahap82@gmail.com
Editorial Address
Jl. SM. Raja, No 27, Kab. Labuhanbatu, Provinsi Sumatera Utara, 21419
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INDONESIA
International Journal of Health and Pharmaceutical (IJHP)
Published by CV. Inara
ISSN : -     EISSN : 2808845X     DOI : https://doi.org/10.51601/ijhp
Core Subject : Health,
International Journal of Health and Pharmaceutical (IJHP) e- ISSN : 2808-845X is a communication media and scientific publication in the health and pharmaceutical fields published by Inara Publisher. International Journal of Health and Pharmaceutical (IJHP) contains articles from research focusing on basic medicine, clinical medicine, epidemiology, preventive medicine (social medicine), pharmacy, and other medical fields. International Journal of Health and Pharmaceutical (IJHP) is published periodically four times a year (February, May, August and November).
Articles 527 Documents
The Relationship between Body Mass Index (BMI) and Hypertension Incidence at Royal Prima Hospital in 2024 Dix Munthe, Dix Munthe; Delfian, Taufik
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025 ( Indonesia - Thailand)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.495

Abstract

Background: Hypertension affects 1.4 billion adults globally and remains inadequately controlled. Body mass index (BMI) accounts for 65 to 75 percent of primary hypertension cases, yet hospital-based evidence from Southeast Asian populations remains limited. Objective: This study determined the relationship between BMI and hypertension incidence at Royal Prima Hospital Medan in 2024. Methods: This cross-sectional analytical study employed total population sampling including 69 respondents meeting inclusion criteria. Data were extracted from medical records and analyzed using univariate analysis and Spearman rank correlation test. Results: Among respondents, 84.1 percent experienced hypertension, with 52.2 percent possessing a BMI greater than 25 kg/m². All respondents with BMI greater than 25 kg/m² exhibited hypertension compared to 66.6 percent of those with normal BMI (p=0.000). Conclusion: A statistically significant relationship exists between elevated BMI and hypertension incidence, confirming obesity as a critical modifiable risk factor for hypertension development in hospital settings. Weight management through lifestyle modification represents an essential intervention strategy for hypertension prevention and control.
Correlation Analysis between Daily Routine Physical Activity and Blood Glucose Control in Diabetes Mellitus Patients at the Kampung Masjid Labuhan Batu Utara Community Health Center Siregar, Rahma; Henny, Henny; Febrini , Dewi
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025 ( Indonesia - Thailand)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.496

Abstract

Elevated blood glucose and low physical activity represent critical health concerns in primary healthcare settings. This study aimed to analyze the correlation between daily routine physical activity and blood glucose control in patients with diabetes mellitus at Kampung Masjid Primary Health Center, North Labuhan Batu. A quantitative descriptive correlational design with cross-sectional approach was employed. Total sampling encompassed 55 diabetes patients meeting inclusion criteria. Data collection utilized the Global Physical Activity Questionnaire (GPAQ) and random blood glucose measurements from medical records. Spearman rank correlation analysis was conducted using SPSS version 25 following KolmogorovSmirnov normality testing. Results demonstrated a significant negative correlation (r = -0.615, p = 0.000) between physical activity levels and blood glucose concentration. Approximately 45.5% of patients engaged in low physical activity, while the mean blood glucose was 307.53 mg/dL, substantially exceeding therapeutic targets. Increased physical activity substantially improved glycemic control, indicating that physical activity represents a critical modifiable factor for diabetes management in primary healthcare. These findings support evidence-based physical activity promotion as essential for integrated diabetes management approaches combining pharmacological intervention with structured exercise supervision at Puskesmas facilities throughout Indonesia.
The Relationship Between Hormonal Contraceptive Use and Breast Cancer Incidence at Dr. Pirngadi Regional General Hospital, Medan Aqilatul Hanisah, Filzah; Hendrianto, Hendrianto
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025 ( Indonesia - Thailand)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.497

Abstract

Breast cancer remains a significant public health concern in Indonesia, with emerging evidence suggesting that hormonal contraceptive type influences not only cancer incidence but also tumor aggressiveness. This cross-sectional study examined the relationship between hormonal contraceptive formulations and histopathological grading of breast cancer at RSUD Dr. Pirngadi Hospital, Medan. The study included 100 women with confirmed invasive breast cancer who were selected using the Lemeshow formula for sample size calculation. A structured data extraction form collected information on contraceptive type, duration of use, and Nottingham grading classification. Fisher's Exact Test and chi-square test analyzed associations between contraceptive types and grading categories. Results demonstrated that oral pill users predominantly developed well-differentiated cancers (51.7%), while injectable users predominantly developed poorly-differentiated tumors (56.3%), representing a highly significant inverse relationship (p-value = 0.000, OR = 0.105). Moderately-differentiated grading showed no significant association with contraceptive type. These findings indicate that contraceptive formulation substantially influences tumor characteristics beyond cancer occurrence alone. The study's cross-sectional design limits causal inference, and future prospective cohort studies with larger samples and comprehensive molecular characterization are needed. The pronounced predominance of aggressive tumor phenotypes among injectable contraceptive users necessitates more intensive breast cancer screening protocols and improved patient counseling regarding differential cancer risks across contraceptive formulations in Indonesian populations.
The Effect of Red Ginger Extract (Zingiber officinale Roscoe, Zingiberaceae) on Analgesia in Male White Rats (Rattus norvegicus) Wistar Strain with Head Injuries Marthin Simbolon, Boyke; Hasanah SB, Nurul; Br Tarigan, Elviyanti
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025 ( Indonesia - Thailand)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.498

Abstract

Head injury represents a significant clinical challenge requiring effective pain management strategies. This study examined the analgesic effects of red ginger extract on head injury in male Wistar rats. The research employed an experimental post-test only control group design with five treatment groups (n = 25 subjects; n = 5 per group). Group K1 received piroxicam (40 mg per 200 g body weight); K2 served as untreated control; groups K3, K4, K5 received red ginger extract at 50, 100, and 150 micrograms per kilogram of body weight per day respectively. Behavioral pain assessment was conducted on days 8 and 21 post-injury using standardized ethological procedures. Statistical analysis utilized Kruskal-Wallis test with post-hoc Mann-Whitney U comparisons. Results demonstrated that K4 (100 μg/kg/day) achieved the lowest mean rank (8.00), indicating superior analgesic efficacy compared to other groups. K4 exhibited comparable effectiveness to piroxicam (K1, mean rank 10.00) and superior outcomes to untreated controls (K2, mean rank 21.60). Selective COX-2 inhibition and inflammatory cytokine reduction mediated these effects. The optimal dose of red ginger extract (100 μg/kg/day) provides significant neuroprotection and may serve as an alternative pain management approach in developing healthcare contexts.
The Relationship Between Nutritional Status and the Incidence of Pneumonia in Toddlers at RS Royal Prima Halim, Yeni; Fariz Hafdar, Alwan; Hakim Nasution, Ikhwanul
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025 ( Indonesia - Thailand)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.501

Abstract

Pneumonia is a type of infectious disease that attacks the lower part of the respiratory system and is one of the leading causes of death in children. One factor that increases the likelihood of children getting pneumonia is their nutritional status. The purpose of this study is to determine the relationship between nutritional status and the incidence of pneumonia in toddlers at RS Royal Prima Medan. The research design is Analytical Observational Quantitative with a Cross Sectional approach and uses the Chi-square statistical test. Data collection was carried out in October 2025 at the Medical Records of RS Royal Prima Medan. The total sample of this study was 167 toddlers who met the Inclusion and Exclusion criteria. The indicators used in this study were Age, Gender, and Nutritional Status. The study results show a p-value (0.020) <0.05, indicating a relationship between Age and the incidence of Pneumonia, and a p-value (0.000) <0.05, indicating a relationship between Gender and the incidence of Pneumonia. The p-value (0.016) <0.05 indicates a relationship between Nutritional Status and the occurrence of Pneumonia. The conclusion of this study is that there is a significant relationship between Age, Gender, and Nutritional Status and the occurrence of Pneumonia in toddlers at Royal Prima Hospital Medan.
The Effect of Laughter Therapy, a Low-Salt Diet, Exercise, and Physical Activity on Reducing Blood Pressure in Elderly Patients at the Sei Kepayang Timur Community Health Center, Asahan Regency RAngelin Purba, Rona; Wahyuni Nasution, Sri; Wienaldi, Wienaldi
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025 ( Indonesia - Thailand)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.502

Abstract

Hypertension is a common health problem among the elderly and carries a risk of increasing cardiovascular complications. Non-pharmacological efforts such as laughter therapy, a low-salt diet, exercise, and physical activity are important strategies in controlling blood pressure. This study aims to analyze the effectiveness of laughter therapy, a low-salt diet, exercise, and physical activity on reducing blood pressure in elderly patients at the Sei Kepayang Timur Community Health Center in Asahan Regency. The study used a quasi-experimental design with a pre-test and post-test control group approach. The number of respondents was 60 elderly people who were divided equally into an intervention group of 30 people and a control group of 30 people. Data were analyzed using comparative statistical tests (paired t-test and chi-square test) with a significance level of p < 0.05. The results showed that in the intervention group, there was a decrease in mean systolic blood pressure from 150.2 mmHg to 135.4 mmHg, with a difference of 14.8 mmHg (p = 0.000), and a decrease in diastolic blood pressure from 93.2 mmHg to 84.4 mmHg, with a difference of 8.8 mmHg (p= 0.000). Other interventions, including a low-fat diet, exercise, and physical activity, were also shown to be effective in reducing both systolic and diastolic blood pressure. In conclusion, laughter therapy, a low-salt diet, exercise, and physical activity are effective in reducing blood pressure in the elderly. Based on these study results, the elderly are advised to regularly engage in laughter therapy, maintain a low-salt diet, and increase physical activity and exercise. Health institutions need to integrate this non-pharmacological intervention program into promotive and preventive services. Future research is expected to examine long-term effectiveness and expand the sample size.
The Relationship Between Medication Adherence Based on the Morisky Medication Adherence Scale 8 (MMAS-8) and the Degree of Disease Activity Based on the Disease Activity Score-28 (DAS28) in Rheumatoid Arthritis Patients at Royal Prima Hospital Amanda Anggraini Harahap, Putri; Yani, Herlina; Budi, Andre
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025 ( Indonesia - Thailand)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.503

Abstract

Rheumatoid arthritis (RA) poses a major health challenge due to poor medication adherence impacting disease control. This study aimed to analyze the relationship between medication adherence (MMAS-8) and disease activity (DAS28) in RA patients. A quantitative cross-sectional design was employed at RS Royal Prima Medan (May-July 2025), targeting outpatient RA patients with consecutive sampling (n=69). Data were collected using validated MMAS-8 and DAS28-CRP instruments, analyzed via Kolmogorov-Smirnov normality tests and Spearman's correlation. Results showed moderate adherence (47.8%), low disease activity predominant (31.9%), and significant moderate positive correlation (r=0.400, p<0.001). Higher adherence is linked to better disease control. Conclusion: Medication adherence moderately influences RA disease activity; multifaceted interventions are recommended.
The Effect Of Health Education In Prevention Hypertension Of Patient Knowledge In Tolo’ Public Health Center Jeneponto District Appulembang, Imelda; Musaidah, Musaidah; Wahyuni Bahrum, Sri; Riani, Jumrah
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 4 (2022): November 2022
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v2i4.134

Abstract

Hypertension can increase the risk of death and complications. Health education is carried out with the aim of increasing health knowledge while increasing public awareness of the importance of maintaining health. It is known that there is an effect of health education in preventing hypertension on the knowledge of patients at the Tolo' Public Health Center, Jeneponto Regency. The type of research used is quantitative with a descriptive research design using a cross sectional approach. To determine the relationship between the independent variable and the dependent variable by using joint measurements, the total population is 170 people, the sampling of this study used purposive sampling technique so that the results were 32 respondents, the data measurement instrument used a questionnaire. There is an effect of health education in preventing hypertension on knowledge of patients and there is an influence of knowledge in preventing hypertension on knowledge of patients at the Tolo' Public Health Center, Jeneponto Regency. obtained p-Value = 0.000 (α<0.05). There is an effect of health education and knowledge in preventing hypertension on knowledge of patients at the Tolo' Public Health Center, Jeneponto Regency.
Comparison of Hemolysis Events and Hematocrit Quality in Leucodepleted (In Line) and Leucodepleted (Bedsite) Clinical Transfusions Novasari Saragih, Frisca; Million, Hendy; Masyitah, Masyitah
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 3 (2023): August 2023
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v3i3.176

Abstract

Blood transfusions no longer provide all the blood components but only provide the necessary blood components. We aim to determine whether there is a comparison of hemolysis events and hematocrit quality in leucodepleted (In Line) and leucodepleted (Bedsite) clinical transfusions. This study was an analytic study with a cross-sectional design to compare hemolysis events and hematocrit quality in leucodepleted (In Line) and leucodepleted (Bedsite) clinical transfusions. We obtained sample data in this study divided into 2 groups, namely the group with leucodepleted in line and the group with leucodepleted bedsite inclusion and exclusion criteria of 58 samples.We found that the incidence of hemolysis after leucodepleted (in line) was 0% and leucodepleted (bedsite) was 0.02%, where the standard percentage of blood hemolysis was <0.8%, the hemolysis incident after the production of the two products was very small. While the hematocrit before and after leucodepleted decreased by 35.91% in leucodepleted (in line) and 33.33% in leucodepleted (bedsite). There is a comparison of the incidence of leucodepleted (In Line) and leucodepleted (Bedsite) hemolysis. Where the incidence of leucodepleted (in line) hemolysis is not found, so the leucodepleted (in line) blood component has good quality. There is a comparison of the quality of leucodepleted (In Line) and leucodepleted (Bedsite) hematocrit.
Evaluation Of Waste Implementation Flow Of Polyclinic Outpatient Service With Blueprint Service At Royal Prima General Hospital, Medan Husni Lubis, Muhammad; Eliza Putri Lubis, Yolanda; Lestari Nasution, Sri
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 3 (2023): August 2023
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v3i3.179

Abstract

Waiting time for services at the hospital is a measure of the quality of services that concern the patient's rights in a service. Long waiting times are felt by patients so that dissatisfaction arises in the service. This study aims to evaluate the waste of polyclinic outpatient services by using a service blueprint to reduce waiting time for services at RSU Royal Prima Medan. This research is descriptive qualitative research involving 89 people consisting of medical staff, non-medical staff, and patients. Sample selection for officers was carried out using purposive sampling, while for patients using accidental sampling. The data in this study were collected through questionnaires, observations and interviews. The validity test of the questionnaire was carried out using Pearson while the reliability test was carried out using Cronbach's Alpha. The results of this study found that the majority of time spent by patients was included in the old category. Researchers also get three types of waste, namely waiting, unappropriate processing, and transportation. Recommendations for efforts to increase waiting time for services that can be done are: rescheduling for doctors, calculating the workload for services that are still managed by 1 officer, planning E-medical records and centralizing them for storing patient files, simplifying providing information to patients, carry out segregation at the poly if it has not been done, and maintain cleanliness and routine maintenance at each supporting facility.