cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Arman Harahap
Contact Email
armanhrahap82@gmail.com
Phone
+6285370005518
Journal Mail Official
armanhrahap82@gmail.com
Editorial Address
Jl. SM. Raja, No 27, Kab. Labuhanbatu, Provinsi Sumatera Utara, 21419
Location
Unknown,
Unknown
INDONESIA
International Journal of Health and Pharmaceutical (IJHP)
Published by CV. Inara
ISSN : -     EISSN : 2808845X     DOI : https://doi.org/10.51601/ijhp
Core Subject : Health,
Nursing Public Health
International Journal of Health and Pharmaceutical (IJHP) e- ISSN : 2808-845X is a communication media and scientific publication in the health and pharmaceutical fields published by Inara Publisher. International Journal of Health and Pharmaceutical (IJHP) contains articles from research focusing on basic medicine, clinical medicine, epidemiology, preventive medicine (social medicine), pharmacy, and other medical fields. International Journal of Health and Pharmaceutical (IJHP) is published periodically four times a year (February, May, August and November).
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 426 Documents
 39   40   41   42   43 
Early Detection of Critical Congenital Heart Disease Through Pulse Oximetry Screening In Resource-Limited Settings Edi Susyanto, M Bambang; Arafuri, Nadya; Ayu Shinta Lesmanawati, Dyah
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.464

Abstract

Critical congenital heart disease (CCHD) is a major cause of neonatal mortality. Early detection using pulse oximetry (SpO₂) within 24–48 hours of life improves survival by identifying hypoxemia before clinical deterioration. A feasibility study in Yogyakarta, Indonesia, screened 1,452 newborns and detected eight CCHD cases (~6 per 1,000 live births), confirming its value in limited-resource settings. A full-term female neonate delivered by elective cesarean section had an initial SpO₂ of 96% but developed cyanosis within 24 hours, with saturation dropping to 90%. Abnormal SpO₂ results led to referral, and echocardiography confirmed critical pulmonary stenosis with PDA and PFO. Balloon valvuloplasty was performed successfully, normalizing oxygen levels. Pulse oximetry screening shows moderate sensitivity (76–83%) and high specificity (~99.9%) for detecting CCHD. Despite logistical and training challenges, it remains feasible and cost-effective in low- and middle-income settings. Integrating SpO₂ screening into routine newborn assessment, supported by national policy and staff training, can enhance early diagnosis and reduce neonatal deaths related to undetected CCHD.
The Relationship Between Personal Hygiene And The Severity of Acne Faculty of Medicine, Prima Indonesia University Year 2025 Nabilah Bancin, Indri; Sartika, Dewi; Nasution, Masdalena
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.470

Abstract

. Acne vulgaris represents one of the most prevalent dermatological conditions affecting adolescents and young adults, with significant psychosocial consequences including reduced self-esteem and quality of life. Despite the high prevalence of acne among Indonesian adolescents (60-80%), comprehensive investigations examining personal hygiene practices and dietary patterns as modifiable risk factors remain limited. This study aimed to examine the relationship between personal hygiene practices and acne vulgaris severity among medical students at Universitas Prima Indonesia. This descriptive cross-sectional study enrolled 197 medical students from the 2022 cohort using total sampling technique. Data were collected through personal hygiene questionnaires, dietary pattern questionnaires, and clinical acne assessment using the Pillsbury classification system. Statistical analysis employed chi-square tests and Spearman correlation coefficient with significance set at p<0.05. Results demonstrated a statistically significant relationship between personal hygiene practices and acne severity (p=0.000), with respondents maintaining good hygiene exhibiting lower acne grades (34.5% Grade 1) compared to poor hygiene (18.8% Grade 1). Similarly, dietary patterns significantly influenced acne outcomes (p=0.000), with high glycemic index foods and excessive dairy consumption correlating with increased acne severity through hyperinsulinemia and elevated insulin-like growth factor-1. Personal hygiene practices and dietary patterns represent modifiable behavioral factors contributing to acne vulgaris severity in medical students, supporting development of targeted prevention and educational intervention strategies.
The Relationship Between Knowledge And Skills of Posyandu Cadres Through The Zero Triple Program For Stunting Prevention In Bubulak Village, Bogor City Hidayat, Nasrul; Azizah, Nain; Ayu Zukhruf Jannah, Ning; Fitria Ramadhani, Putri; Prameswari Nursaadah, Salma
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.473

Abstract

Background: Stunting remains one of the major nutritional problems affecting children's growth and development in Indonesia, including in Bogor City. Posyandu cadres play a crucial role in providing education and implementing stunting prevention efforts. However, limited knowledge and practical skills among cadres in carrying out these activities in the field remain significant challenges that need to be addressed. Objective: This study aims to determine the relationship between the level of knowledge and skills of Posyandu cadres through the implementation of the Zero Triple Program and their efforts in stunting prevention in Bubulak Subdistrict, Bogor City. Method: This study employed a quantitative descriptive method with a pre-experimental one-group pretest–posttest design. The program was conducted over four sessions involving 21 Posyandu cadres. The stages included preparation, socialization and program introduction, delivery of balanced nutrition materials through the Isi Piringku educational game demonstration, training on tilapia fish and hydroponic cultivation, demonstration of tilapia dim sum processing, as well as mentoring and evaluation through pre-test and post-test assessments. The data obtained were then processed and analyzed using Microsoft Excel Results: The average pre-test score increased from 17.0 to 19.4 for the stunting material, 18.0 to 19.5 for the balanced nutrition material, and 1.19 to 2.10 for the hydroponic cultivation and tilapia processing training. These results indicate a significant improvement in the knowledge and skills of respondents after participating in the zero triple program. Conclusion: There is a significant relationship between the implementation of the zero triple program and the improvement of Posyandu cadres' capacity in delivering education and practical stunting prevention efforts in Bubulak Village, Bogor City. Suggestion: Future studies are recommended to involve a larger number of respondents and include an evaluation of cadres' behavioral changes following the training program to strengthen the sustainability and impact of community-based stunting prevention initiatives.
Characteristics of Breast Cancer at Royal Prima Hospital, Medan, 2020-2025 Dewani Silaban, Grace; Puspawani, Yeni; Eliza Putri Lubis, Yolanda
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.481

Abstract

Background: Breast cancer represents a significant global health burden, particularly in Southeast Asian populations. This study characterizes breast cancer patients in a North Sumatran tertiary hospital. Objectives: To describe demographic characteristics, histopathological classification, and clinical outcomes of breast cancer patients. Methods: A retrospective descriptive cross-sectional study was conducted at Royal Prima Hospital Medan using total enumeration sampling of 19 breast cancer patients with complete medical records from 2020 to 2025. Data on age, gender, histopathological type, and hospitalization duration were extracted from medical records. Descriptive statistics using SPSS software analyzed frequency distributions and percentages. Results: Nineteen patients demonstrated a mean age of 49.3 years, predominantly pre-elderly females (78.95%). Invasive ductal carcinoma and invasive lobular carcinoma were the main histological types. Mean hospitalization duration was 7.5 days, ranging from 2 to 18 days, influenced by surgical complexity and postoperative complications, including seroma formation and wound dehiscence. Conclusion: This institutional characterization provides baseline epidemiological data on breast cancer presentations, emphasizing the need for enhanced screening, early detection programs, and optimized surgical management protocols to improve outcomes.
The Relationship Between Adherence To Antidiabetic Treatment and Hba1c Values In Type 2 Diabetes Mellitus Patients At Royal Prima Hospital, Medan, In 2025 Hafni Lubis, Azijah; Elviyanti, Elviyanti; Boyke, Boyke
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.482

Abstract

Type 2 diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia from inadequate insulin synthesis or insulin resistance. Medication adherence significantly impacts glycemic control measured by HbA1C levels. This study examined the relationship between antidiabetic medication adherence and HbA1C levels in type 2 diabetes patients. This analytical cross-sectional study enrolled 77 outpatients at Royal Prima General Hospital, Medan. The Morisky Medication Adherence Scale (MMAS-8) questionnaire assessed adherence, while HbA1C levels were extracted from medical records. Chi-square analysis (p less than 0.05) and odds ratio calculations were performed using IBM SPSS Statistics. Results demonstrated that 77.9% of patients exhibited uncontrolled HbA1C levels above 7%, with 76.6% showing moderate to low medication adherence. Statistical analysis revealed a highly significant association (χ² = 17.661, p = 0.003, OR = 11.621), with patients demonstrating low adherence experiencing 11.621-fold increased odds of uncontrolled HbA1C. Notably, zero patients with low adherence achieved adequate glycemic control. The study concludes that medication adherence represents a critical modifiable determinant of glycemic control. Systematic adherence screening, targeted barrier-specific interventions including medication reminders and patient education, and enhanced provider communication should be integrated into routine diabetes management to optimize glycemic control and reduce diabetes-related complications.
The Relationship Between Chronic Kidney Disease and the Severity of Pruritus in Patients Undergoing Hemodialysis at Royal Prima General Hospital in Medan Fazriani, Popy; Arhamni, Ade; Siregar, Lisdawaty
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.483

Abstract

Chronic kidney disease-associated pruritus represents a prevalent complication that significantly impairs hemodialysis patient quality of life. This study examined the relationship between hemodialysis duration and uremic pruritus severity. An analytical cross-sectional design enrolled 34 chronic kidney disease patients receiving maintenance hemodialysis at Royal Prima General Hospital, Medan. Data collection utilized questionnaires and medical records; purposive sampling identified meeting participants inclusion criteria. Univariate analysis described demographic and clinical characteristics using frequency distributions. Bivariate chi-square analysis tested associations between hemodialysis duration (categorized as less than 6 to 12 months, 13 to 24 months, and greater than 24 months) and pruritus severity (mild, moderate, severe) using IBM SPSS Statistics software. Results demonstrated a highly significant association between dialysis duration and pruritus severity (χ² = 17.661, p = 0.000), with severe pruritus occurring in 0% of early-stage dialysis patients, 16.7% of intermediate-duration patients, and 82.4% of long-term recipients. Extended hemodialysis exposure correlates directly with progressive pruritus escalation through cumulative uremic toxin accumulation and inflammatory activation. These findings substantially systematic pruritus screening and multimodal management implementation for all dialysis patients, particularly targeting long-term recipients experiencing substantial symptom burden.
Factors Affecting The Incidence of Dengue Hemorrhagic Fever (DHF ) At Tumpaan Health Center, South Minahasa Regency Yulli Turang, Revony; D. Kandou, Grace; M. Mantjoro, Eva
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v4i4.66

Abstract

This study presents a comprehensive analysis of the factors influencing Dengue Hemorrhagic Fever (DHF) incidence in the working area of Puskesmas Tumpaan, South Minahasa. Utilizing a case-control design, 88 respondents—44 laboratory-confirmed DHF cases and 44 matched controls—were assessed to determine the association between behavioral and environmental risk factors and DHF transmission. Five key variables were examined: level of public knowledge, vector control practices (PSN), indoor clothing habits, household cleanliness, and water storage conditions. Bivariate and multivariate statistical analyses were employed to evaluate significant predictors of disease occurrence. The results identified knowledge about DHF (OR = 0.27; p = 0.013) and the habit of hanging clothes indoors (OR = 0.15; p = 0.000) as significant risk factors. Other variables—PSN, household cleanliness, and water storage—showed no statistical significance but remain epidemiologically relevant. These findings indicate that behavioral factors, particularly knowledge and indoor clothing practices, play a central role in influencing dengue transmission in endemic regions. The study underscores the importance of integrated health education and behavior-focused interventions in dengue prevention strategies.
Hba1c and Blood Pressure Correlation In Patients With Uncontrolled Type 2 Diabetes Mellitus Muhammad Gugun, Adang; Suryanto, Suryanto; Emil Fadli Nugroho, Muhammad; Bintang Bari, Pravda
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v2i3.76

Abstract

The primary metabolic disorder in diabetes mellitus is hyperglycemia, which can be assessed through glycated hemoglobin (HbA1c) levels as an indicator of long-term blood glucose control. Abnormal glucose metabolism may affect vascular function and contribute to increased blood pressure, making hypertension a common complication among patients with uncontrolled diabetes mellitus. This study aimed to determine the correlation between HbA1c levels and blood pressure in patients with uncontrolled type 2 diabetes mellitus. An observational cross-sectional study was conducted at RSU PKU Muhammadiyah Gamping involving 90 subjects aged 31–65 years, consisting of 48 men and 42 women. HbA1c levels were measured using the boronate affinity method, and blood pressure was assessed with a sphygmomanometer. Statistical analysis used the independent t-test, Mann–Whitney U test, and Spearman correlation with a significance level of α = 0.05. The mean HbA1c level was 10 ± 2.08%, mean systolic pressure 132.75 ± 18.04 mmHg, and mean diastolic pressure 83.28 ± 10.38 mmHg. Hypertension occurred in 36.66% of subjects. The results showed no significant differences in blood pressure between sexes or glycemic control groups and no significant correlation between HbA1c levels and blood pressure. These findings suggest that factors other than glycemic control may influence blood pressure in diabetic patients.
Correlation Between Hba1c Levels, Emotional Stress And Dm Distress In Type 2 Diabetes Mellitus Patients Muhammad Gugun, Adang; Alam Romadhon Suryanto, Yusuf; Emil Fadli Nugroho, Muhammad; Bintang Bari, Pravda
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.376

Abstract

This study aimed to examine the correlation between HbA1c levels, emotional distress, and diabetes-related distress (DM distress) among patients with type 2 diabetes mellitus (T2DM). Poor diabetes control and life stressors often lead to increased emotional and DM distress, which may elevate blood glucose through activation of the hypothalamic–pituitary–adrenal (HPA) axis. An analytical observational method with a cross-sectional design was used. Participants were outpatients with T2DM at PKU Muhammadiyah Gamping Hospital, selected using purposive sampling based on inclusion and exclusion criteria. HbA1c levels were analyzed using the boronate affinity method. Emotional distress was measured using the Depression Anxiety Stress Scale (DASS-42), and DM distress was assessed using the Diabetes Distress Scale (DDS-17). Statistical analysis employed the Shapiro–Wilk test for normality and the Spearman correlation test, with a significance level of α = 0.05. A total of 45 subjects participated (23 males and 22 females). The mean HbA1c level was 9.2 ± 2.6%, the mean emotional distress score was 80.2 ± 19, and the mean DM distress score was 2.49 ± 0.93. The results revealed significant positive correlations between HbA1c levels and emotional distress (r = 0.46, p = 0.001), HbA1c levels and DM distress (r = 0.52, p = 0.000), and between emotional distress and DM distress (r = 0.62, p = 0.000). These findings indicate that higher emotional and DM distress are associated with poorer glycemic control. Integrating psychosocial evaluation and emotional support into diabetes care is essential to improve metabolic and psychological outcomes in T2DM patients.
Febuxostat In Hyperuricemic Heart Failure: A Systematic Review of Cardiovascular Outcomes and Safety Warham, Warham; Octavien Wijaya, Jonea; Valerian Soumokil, Willy; Islamy, Nur; Afiah Sudarianto, Nurul
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.469

Abstract

Introduction: Hyperuricemia is highly prevalent in patients with heart failure (HF) and is associated with poor prognosis. Febuxostat, a selective non-purine xanthine oxidase inhibitor, provides potent urate-lowering effects and may reduce oxidative stress, but its cardiovascular safety in HF populations remains uncertain. Objective: To systematically review the evidence on febuxostat use in patients with hyperuricemia and heart failure, focusing on cardiovascular outcomes, safety, and mechanistic effects. Methods: This review was conducted according to PRISMA guidelines. Comprehensive searches of PubMed, Cochrane Library, and ScienceDirect up to September 2025 identified studies evaluating febuxostat in hyperuricemic HF patients. Eligible designs included randomized controlled trials, post hoc analyses, and observational cohorts. Data were extracted on study characteristics, interventions, comparators, outcomes, and risk of bias. Results: From 247 records screened, eight studies were included in the qualitative synthesis. Febuxostat consistently reduced serum uric acid levels and improved oxidative stress markers and diastolic function indices. Clinical outcome data were heterogeneous: while one large trial reported increased cardiovascular mortality, another demonstrated non-inferiority without excess risk. Subgroup and observational data suggested that HFpEF patients may benefit from febuxostat in terms of reduced hospitalization and mortality, whereas evidence in HFrEF was inconclusive. Risk of bias was generally low in randomized trials but higher in observational studies. Discussion: The findings highlight febuxostat’s mechanistic plausibility and potential phenotype-specific benefits, particularly in HFpEF. However, conflicting mortality signals from pivotal trials necessitate cautious interpretation. Limitations include small sample sizes in HF-focused studies, heterogeneity in patient populations, and limited long-term outcome data. Conclusion: Febuxostat is a potent urate-lowering therapy with mechanistic benefits in hyperuricemic HF, but evidence on clinical outcomes remains inconsistent. Selective use in carefully chosen HFpEF patients may be considered, pending further large randomized trials to clarify safety and efficacy.

Page 41 of 43 | Total Record : 426

 39   40   41   42   43 

Filter by Year

2021 2025


Reset
Filter By Issues
All Issue Vol. 5 No. 4 (2025): November 2025 Vol. 5 No. 3 (2025): August 2025 (Indonesia - Malaysia) Vol. 5 No. 2 (2025): May 2025 ( Indonesia - Iraq - Malaysia) Vol. 5 No. 1 (2025): February 2025 (Indonesia - Turkey - Malaysia - Australia - Iran) Vol. 4 No. 4 (2024): November 2024 Vol. 4 No. 3 (2024): August 2024 Vol. 4 No. 2 (2024): May 2024 Vol. 4 No. 1 (2024): February 2024 Vol. 3 No. 4 (2023): November 2023 Vol. 3 No. 3 (2023): August 2023 Vol. 3 No. 2 (2023): May 2023 Vol. 3 No. 1 (2022): February 2023 Vol. 2 No. 4 (2022): November 2022 Vol. 2 No. 3 (2022): August 2022 Vol. 2 No. 2 (2022): May 2022 Vol. 2 No. 1 (2022): February 2022 Vol. 1 No. 1 (2021): November 2021 More Issue