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Jurnal Farmasi Sains dan Praktis
Published by Universitas Muhammadiyah Magelang
ISSN : 25499068     EISSN : 25794558     DOI : -
Core Subject : Health, Science,
Immunology & microbiology Medicine & Pharmacology Public Health
Jurnal Farmasi Sains dan Praktis aims to serve the updated scientific knowledge for international researchers in pharmaceutical sciences. Jurnal Farmasi Sains dan Praktis (JFSP) publishes review article, original article, as well as short communication in the all scopes of Pharmaceutical Science such as Pharmaceutics, Biopharmaceutics, Drug Delivery System, Physical Pharmacy, Pharmaceutical Technology, Pharmaceutical Microbiology and Biotechnology, Pharmacology and Toxicology, Pharmacokinetics, Pharmaceutical Chemistry, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Marketing, Alternative Medicines, Pharmaceutical Management, Pharmacoeconomic, Pharmacoepidemiology, Social Pharmacy, Pharmacy Policies.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 259 Documents
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FORMULATION AND PHYSICAL PROPERTIES OF CANDLENUT OIL GEL POMADE (Aleurites Mollocana Wild) Wilda Amananti; Aldi Budi Riyanta
Jurnal Farmasi Sains dan Praktis Vol 6 No 2 (2020)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v6i2.3162

Abstract

The use of pomade for a long time will cause hair damage. Pomade with preferred ingredients, because it is very good for beauty and hair health. Liquid oil is one of the basic ingredients used in making pomade. Candlenut oil can be used as liquid oil for the pomade base. This article examines the formulation and physical properties of pomade from candlenut oil. There are four formulas that have been made with different F0 candlenut oils without candlenut oil, F1 with 10% candlenut oil, F2 with 20% candlenut oil, F3 with 30% candlenut oil. The difference in concentration is indicated to affect the physical differences of the candlenut oil pomade. Physical properties of Candlenut Oil Pomade gel include organoleptic, homogeneity, scattering test, sticky test. The results showed that all formulas showed homogeneous gel preparations. Formula 3, with the highest concentration of candlenut oil concentration of 30%, shows a greater dispersion than a formula with other substances reaching 6.5 cm and meets SNI standards, which will increase the adhesion, which does not meet the standard.
SATISFACTION AND WILLINGNESS TO PAY PHARMACISTS COUNSELING SERVICES IN SURAKARTA Mariska Sri Harlianti; Khusnul Novitasari
Jurnal Farmasi Sains dan Praktis Vol 6 No 1 (2020)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v6i1.3173

Abstract

Satisfaction was an indicator to assess the quality of counseling services by pharmacists in pharmacies. Willingness to Pay (WTP) was an approach that can be used to measure the indirect benefits of a program. Satisfaction and WTP have a positive correlation. The increasing level of consumer satisfaction caused an increase in the value of WTP. The purpose of this study was to measure the satisfaction and WTP value of counseling services by pharmacists and the relationship between them. Non-experimental research with cross sectional design was conducted on 100 patients who visited the pharmacy and received counseling services by the pharmacist. Satisfaction was measured based on 4 dimensions, namely: tangible, reliability, assurance, and empathy. WTP value was determined using the payment card method. The relationship between the two variables was analyzed by the Pearson correlation (p-value <0.05). The results showed that the level of satisfaction and WTP of counseling services by pharmacists in the Surakarta city pharmacy was 0.93 and Rp 20,652 and there was no relationship between them (Sig. = 0.422). The high level of satisfaction showed that the quality of service was also good. However, it did not affect respondents to pay for counseling services by pharmacists in the Surakarta city area pharmacy with a relatively higher value when compared to other professions
THE INFLUENCE OF SOCIODEMOGRAPHIC FACTORS ON KNOWLEDGE AND ATTITUDES ABOUT THE USE OF ANTIBIOTICS IN RURAL COMMUNITIES: OBSERVATIONAL STUDY IN CEMPAKA BANJARBARU DISTRICT Rahmayanti Fitriah; Nurul Mardiati
Jurnal Farmasi Sains dan Praktis Vol 7 No 1 (2021)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v7i1.3181

Abstract

Antibiotics are examples of drugs that are often used incorrectly. Such misuse is often influenced by the lack of knowledge and attitudes towards the use of antibiotics, so in this study we want to know what sociodemographic factors have an influence on knowledge and attitude on antibiotic use in rural communities at Cempaka Banjarbaru District, South Kalimantan, Indonesia. This type of research is descriptive analytic with a sampling technique that is proportional stratified random sampling using a questionnaire. There are 380 respondents taken as a sample. Analysis data used is univariate and bivariate with chi-square test. The result of public knowledge research on the use of antibiotics included in the good category that is 58.2 % and attitudes included in the positive category that is 98.4 %. Statistical test results show that there is a significant influence between sociodemographic factors of recent education and income on the level of knowledge, while sociodemographic factors of age, sex and occupation on the level of knowledge have no significant effect. On the results of statistical tests sociodemographic factors (age, sex, occupation, last education and income) on attitudes do not have a significant effect.
EVALUATION OF ANTIBIOTIC IN ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS WITH FEBRILE NEUTROPENIA Ambar Yunita Nugraheni; Safira Salsabilla Rizki Rahardiani
Jurnal Farmasi Sains dan Praktis Vol 6 No 1 (2020)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v6i1.3192

Abstract

Patients with hematological malignancy have a high risk of experiencing febrile neutropenia (FN). Acute Lymphoblastic Leukemia (ALL) became one of the most cases as a cause of FN. Chemotherapy can also cause of neutropenia in almost 90% of cases and can increase the risk of developing febrile neutropenia. The administration of irrational antibiotics can cause problems such as increased side effects and resistance. The purpose of this study is to determine the rationality of antibiotics in ALL with FN patients at hospital X Surakarta. This study was an observational study with retrospectively. The research sample was met the inclusion criteria 31 patients with the purposive sampling method. Data were analyzed descriptively. An evaluation antibiotic of 31 patients ALL with FN was obtained the right indication 100% (31 patients), the right patient 100% (31 patients), the right medicine 83,87% (26 patients) and the right dose 51,61% (16 patients). The rationality of antibiotics was 51,61% (16 patients).
COMPARISON OF ANTI ASTHMA ACTIVITY BETWEEN EXTRACT AND OIL Nigella sativa ON HISTOPATHOLOGY OF BRONCHIAL EPITHELIAL IN ASTHMA MICE Dian Arsanti Palupi; Salwa Rahmawati; Annis Rahmawaty; Endra Pujiastuti
Jurnal Farmasi Sains dan Praktis Vol 6 No 1 (2020)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v6i1.3193

Abstract

Asthma is an inflammatory disease or chronic airway inflammation. Nigella sativa extract and oil are proven to be used to improve airway inflammation. This study consisted of 7 groups. The normal group (K1), negative group (K2), theophylline (K1), Nigella sativa extract (K4), Nigella sativa oil (K5). 0.9% intraperitoneally, and on the 14th day, the mice were re-sensitized intraperitoneally with a 20µg OVA + 2 mg of Alhydrogel in 1 mL of sterile NaCl 0.9%. On the 21st, 23rd, 25th day, the OVA1% was inhaled. On the 26th to 39th day, the K3 mice were given theophylline 0.338 mg/day, K4 mice were given Nigella sativa extract at a dose of 1 mL/day and K5 mice were given Nigella sativa oil at a dose of 0.1mL / day. On the 40th day, the mice were terminated for analysis of the thickness of the bronchial epithelium. Comparison between groups of Nigella sativa extract on average 15.5 ± 2.22 µm and Nigella sativa oil average of 14.05 ± 3.87 µm p-value = 0.488 means that between the Nigella sativa extract group and Nigella sativa oil there was no difference meaningful. statistically as an antiasthma in decreasing the size of the thickness of the bronchial epithelium
TOTAL FLAVONOID DETERMINATION AND ANTIOXIDANT ACTIVITY STUDY OF SPINACH (Amaranthus tricolor L.) RED GITI AND GREEN GITI VARIETY Any Guntarti; Anita Ruliyani
Jurnal Farmasi Sains dan Praktis Vol 6 No 1 (2020)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v6i1.3196

Abstract

Antioxidants in the form of total flavonoids are compounds that can stabilize freeradicals. The mechanism of antioxidants in stabilizing free radicals is give the lackelectron of free radicals and inhibit the formation of free radical formation thatcan damage the body. DPPH method is used to determine the activity of capturingfree radicals of ethanol extracts of Amaranthus tricolor L. red giti and green giti.As a positive control quercetin is used. The results showed that the total amount offlavonoids in red giti spinach was (5.615±0.114)% EK and green giti spinach was(4.468±0.166)% EK. The results also show that all groups have activity as freeradical scavengers. The value of ES 50 for positive control quercetin, red gitispinach extract, and green giti spinach extract are (1.375±0.085)µg/ml,(186.198±0.363)µg/ml, and (209.392± 0.607)µg/ml respectively. Based on ES 50values It can be concluded that antioxidant activity of red giti spinach extract andgreen giti spinach extract are significantly different from the positive controlquercetin. Antioxidant activity of quercetin is categorized strong antioxidantactivity, while the antioxidant activity of red giti spinach extract and green gitispinach extract is categorized as weak antioxidant activity.
QUANTITATIV ANALYSIS AND PHARMACOECONOMICS OF ANTIBIOTIC USE IN COMMUNITY-ACQUIRED PNEUMONIA (CAP) IN PKU MUHAMMADIYAH GAMPING Ayunda Putri Hadiningrat; Akrom -; Risdiana Irma
Jurnal Farmasi Sains dan Praktis Vol 7 No 1 (2021)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v7i1.3251

Abstract

Antibiotics are therapies used in cases of infection. Inappropriate use of antibiotics will cause the impact of resistance. Antibiotic use studies need to be done as a step to reduce this impact. The purpose of this study was to determine the practice of using antibiotics by measuring the quantity using the Defined Daily Dose (DDD) and DU90% method in inpatients with a diagnosis of Community-Acquired Pneumonia (CAP) at PKU Muhammadiyah Gamping Hospital. This study is a retrospective study on inpatients of PKU Muhammadiyah Gamping Hospital in 2016-2018. Data was obtained from patient medical records. The results showed a change in the pattern of antibiotic used in 2016-2018. Ceftriaxone and ceftazidime are the most widely used antibiotics. Ceftriaxone with a DDD value of 12.59; 22.49; 23.53 / 100 bed-days and ceftazidime with a DDD value of 17.09; 12.98; 10.59 / 100 bed-days. Antibiotics that are included in DU 90% are Ceftriaxone, Ceftazidime, Cefixime and Levofloxacine. The conclusion of this study is that there is a change in the pattern of antibiotic use in cases of Community-Acquired Pneumonia (CAP) in 2016-2018.
COST OF ILLNESS OF INPATIENT PEDIATRIC MENINGITIS PATIENTS HOSPITALIZED IN YOGYAKARTA Ingenida Hadning; Dwi Endarti; Tri Murti Andayani; Rina Triasih
Jurnal Farmasi Sains dan Praktis Vol 6 No 1 (2020)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v6i1.3292

Abstract

This research to determine the average cost of illness of inpatient pediatric meningitis patients hospitalized in the hospitals in Yogyakarta. It was a pharmacoeconomic study using the cost of illness method. The calculation of the cost in the care of inpatient pediatric meningitis patients according to a societal perspective was conducted observatively with a cross sectional design. Cost of illness analysis included calculating the costs of direct medical, direct non-medical, and indirect cost. Data were collected from a type-A public hospital and a type-B privatehospital in Yogyakarta by taking medical records, detailed data on meningitis patient care costs, and interviews using questionnaires with caregivers. Analysis of cost of illness calculations applied descriptive analysis methods. In this study, 11 inpatient pediatric meningitis patients were obtained. The average cost of illness for the treatment of inpatient pediatric meningitis patients was IDR 26,224,586±12,814,789, consisting of the average direct medical cost of IDR 23,831,813±12,222,885 (90.88%), the average direct non-medical cost of IDR 1,787,955±832,353 (6.82%), and the average indirect cost of IDR 604,818±337,389 (2.31%). Components of direct medical cost with the largest percentage were drugs and medical supplies (26.46%); while the largest direct non-medical cost were the expenditure of additional needs for the patient's family (72.18%). The indirect cost component came from the reduction of the patient's parents' income while the patient is hospitalized.
ANALYSIS CORRELATION DURATION OF USE WITH RISK OF INCREASED BLOOD PRESURE ON THE ACCEPTORS INJECTABLE CONTRACEPTIVE DEPO MEDROXYPROGESTERON ACETATE (DMPA) : A RETROSPECTIVE COHORT STUDY Sekar Muktiyani; Nurmainah Nurmainah
Jurnal Farmasi Sains dan Praktis Vol 6 No 2 (2020)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v6i2.3297

Abstract

Depo Medroxyprogesterone Acetate (DMPA) is a method of family planning program. DMPA is preferred because of its economical, practical, and effective in preventing pregnancy. Long-term use DMPA is suspected to be a risk of an increase in blood pressure. The purpose of this study was to analyze the correlation between duration of use with risk of hypertension in the DMPA acceptor at Perumnas II Pontianak Public Health Care. The research method was observational analytic with a retrospective cohort design. The population of the study is the new DMPA acceptor January-June 2018. This period is the index date for the use of DMPA or the date of the first use of DMPA by acceptors. The acceptor is followed by using DMPA for one year or more until the end of the 30 June 2019 study through its medical record data. Samples that met the inclusion and exclusion criteria were 81 acceptors. The results showed that acceptors with a duration of use of DMPA for more than 12 months had more risk of hypertension (66.7%) than acceptors with a duration of use for less than 12 months (38.5%). Chi-square analysis showed a significant correlation between the duration of use of DMPA and the risk of hypertension (p-value = 0.011, RR = 1.733 CI 95% = 1.104 - 2.72 in DMPA acceptor at Perumnas II Pontianak Public Health Care. The study concludes that there is a correlation between duration of use and risk of hypertension.
OFF-LABEL PEDIATRIC DRUG USE IN INDONESIA : A SYSTEMATIC REVIEW Dewi Latifatul Ilma; Nialiana Endah Endriastuti
Jurnal Farmasi Sains dan Praktis Vol 6 No 1 (2020)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v6i1.3407

Abstract

The phenomenon of off-label drug use has been widely observed in the pediatric population, including in Indonesia. The major concern arising from the prevalence of off-label drug use is the increased risk of adverse drug reactions. We performed a systematic review to describe and provide insight into off-label pediatric drug use in Indonesia. The articles published using English and Indonesian language was systematically searched in five electronic databases, including Pubmed, Scopus, Google Scholar, Garuda, and Neliti. Key terms used for the search were as follows: "off-label use", "off-label”,"child", "pediatrics", "infant","adolescent", "newborn", "Indonesia". A total of one hundred sixteen studies were initially obtained from an electronic database. Further, after the references were reviewed, ten articles met all the eligibility criteria that were finally selected. The percentage of off-label pediatric drug use was 32.6-89.9%. The off-label categories in the selected studies were age, dosage, contraindication, route of administration, and indication. Among these off-label categories, age was the highest off-label with percentages ranged from 19.8 to 92.9%. Pseudoephedrine hydrochloride and triamcinolone acetonide became the most frequently used drug in that category. Thus we conclude that off-label pediatric drug use is common in Indonesia. Future research should consider the safety of off-label drugs in pediatric, primarily in Indonesia. Clinicians should be aware of off-label drugs in pediatrics and consider the risk-benefit of the drugs when prescribing to children. The authorities need to regulate off-label drug prescribing in pediatrics; therefore, it could improve medication safety and quality.

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