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Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Published by Universitas Muhammadiyah Surakarta
ISSN : 24773328     EISSN : 28077245     DOI : -
Core Subject : Health, Science, Education, Social, Engineering,
Computer Science & IT Engineering Medicine & Pharmacology Social Sciences Other
The International Summit on Science, Technology and Humanity (ISETH) is organised by Universitas Muhammadiyah Surakarta. This summit aims to provide a platform for researchers and academics to share their research findings with others and meet lecturers and researchers from other institutions and to strengthen the collaboration and networking amongst the participants.
Arjuna Subject : Umum - Umum
Articles 1,013 Documents
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Corruption and Public Budgeting in the Local Government in Indonesia Sunarti, S; Susilo, Totok; Sriyanto, S
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2019: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.1422

Abstract

The trend of corruption cases by regional heads and members of the Regional House of Representatives increased after the reform. In 2004-2017 there were 392 Regional Heads involved in legal issues, the largest number of corruption cases were 313 cases. Indonesia consists of 34 provinces with diverse demographic structures and also various public problems. The research objective was to analyze the effect of misuse of public budgets on the level of corruption in Indonesia. A large enough of public budget tends to trigger corruption in Indonesia. This research is useful for regional governments to be more transparent and accountable in the use of public budgets. In addition, this research is useful for policy makers to make better control tools. The data collection consisting of regional government financial reports that have been audited by the Supreme Audit Board in Indonesia. Reports LG financial reports will be analyzed to determine the amount of public budget in each region, the amount of regional loss from regulatory non-compliance and the level of corruption in Indonesia. This research applied panel data using the help of Eviews 8 application for data processing. The results of this research indicated that the public budgeting does not affect the level of corruption in the local government of Indonesiain. In this study the public budget is measured by the amount of funds or costs for the public, so it does not affect the level of corruption. The amount of funds budgeted to the public does not affect the level of corruption. corruption of public budgets is influenced by transparency and accountability in the use of public budgets.
Conceptual Model of Accelerating the Adoption of Small and Medium Industries in Implementing Industry 4.0 with the Lean Manufacturing Approach Muizzullah, Risma Fattahatin; Komarudin, K; Hidayatno, Akhmad
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2019: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.1423

Abstract

Purpose: Making a conceptual model that can provide the policy strategy in accelerating the adoption of industry 4.0 in Small and Medium Industries (SMI) using lean manufacturing approach.Methodology: Using the conceptualization process in system dynamics methodology to get causal relation among the factors which can affect the implementation of industry 4.0 in Small and Medium Industries. The lean management approach was used to get these factors and compile their causal relation with readiness of industry 4.0 as a conceptual model.Result: A conceptual model that shows important variables and its relationship structure that could be used in better understanding the adoption proceeses of Industry 4.0 technology. Several interconnection loops are identified in the conceptual model that can be the basis for better policy design by focusing on adjusting one or more variables in the loops, in the manner of understand the relationships that occur in the conceptual model, the government can predict the outcome of the policy to be implemented. Applications/Originality/Value: Providing a better understanding of adoption process for better policymaking by the Indonesian government, particularly the Ministry of Industry, to encourage the readiness of industry 4.0 implementation in Small and Medium Industries.
The Economic Valuation of Tourism Sector and Poverty Reduction in Kota Batu: Travel Cost Method (TCM) Approach Wahyudi, Setyo Tri
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2019: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.1424

Abstract

Kota Batu, as one of the tourist destinations in East Java, has long been known as the best tourism destination. On the other hand, Kota Batu also still has a problem regarding poor people. The tourism sector is seen as a growth strategy that enables the economy to grow, has the potential to improve the local economy, and able to reduce poverty. This study aims to measure the economic valuation of the tourism sector and its contribution to poverty reduction. The respondents and research samples are visitors to the tourist village of Bumiaji District, Kota Batu. Using the travel cost method, the results of the study showed that the economic valuation of the tourist village of the Bumiaji District provided substantial value and ability to contribute to poverty reduction in the area. Village tourism visitors also benefit (consumer surplus) because of the relatively low average costs to be borne compared to the willingness to pay.
The Economic, Moral and Spiritual Accountability at Kamaran Villa Business and It’s Relevance in a Suluk Linglung Sunan Kalijaga Mennita, Ria; Soeherman, Bonnie
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2019: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.1425

Abstract

Tourism Area of Prigen or Prigen Village is a area where “Kamaran” Villa business operates in Pasuruan Regency. Kamaran Villa is a villa that provides rental services per room, either short time or full time. Business of “Kamaran” Villa presents pros and cons on its accountability reality. This research aims to uncover the economic, moral and spiritual accountability of Villa Kamaran business, to interpret it and to serve it with the teachings in the Suluk Linglung Sunan Kalijaga. This research is a qualitative study with the Phenomenology approach. The results showed that this business could be accountable economically, but could not be accountable morally and spiritually. The teachings in the Suluk LingLung Sunan Kalijaga, which is the colors of lust in the human body can reflect the factors that affecting the acceptance and assessment of the owner and Prigen’s people to business accountability of “Kamaran” Villa. The value in Suluk Linglung is able to bring the achievement of an accountable business where accountability must lead to worship and not prioritize on worldly gains.
Antibacterial Activity of Extract and Fraction of Baccaurea macrocarpa Leaf on Escherichia coli and Bacillus cereus Zamzani, Irfan; Triadisti, Nita
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2019: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.1426

Abstract

Purpose: The purpose of the present study is to investigate antibacterial activity of extract and fraction of Baccaurea macrocarpa leaf, and to identify secondary metabolite contents of the best activity.Methodology: Baccaurea macrocarpa leaf was extracted by using maceration method with the use of methanol solvent. The extract was then fractionated by adopting n-hexane and ethyl acetate by using liquid-liquid extraction. Antibacterial activity assay was performed by using inhibition zone assay particularly Disc Diffusion Susceptibility method from methanol extract and fraction extract of ethyl acetate and n-hexane. Phytochemical screening as the best activity was performed by using by adopting Thin Layer Chromatography (TLC). Result: Antibacterial activity was identified in the ethyl acetate extract of Baccaurea macrocarpa leaf. In addition, secondary metabolites with the best activity such as alkaloid, anthraquinone, flavonoid, and tannin were identifiable in the fraction extract of ethyl acetate of Baccaurea macrocarpa.
Anti-inflammatory Activities of Methyl trans-Cinnamate derivatives on Carrageenan-Induced Paw Edema in Male Sprague Dawley Rats Ernawati, Teni; Yuliani, Tri; Minarti, M; Dewijanti, Indah Dwiatmi
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2019: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.1427

Abstract

Purpose: The purpose of this study was to evaluate the anti-inflammatory activity of cinnamic acid and 3-phenyl propanoic acid and also virtual screening of the methyl trans-cinnamate derivatives were carried out on the COX-2 enzyme.Methodology: The cinnamic acid and 3-phenylpropanoic acid were tested for anti-inflamatory activity in vivo using carageenan-induced rat paws edema method. Thirty male Sprague-Dawley rats were divided into 5 groups: control group, Na diclofenac (0.45 mg/kg body weight), ibuprofen (7.2 mg/kg body weight ), cinnamic acid (14.4 mg/kg body weight) and 3-phenyl propionate acid (14.4 mg/kg body weight). Paw edema was observed using a plethysmometer for 46 hours, these were at 0, 0.5, 2, 3, 4, 5, 22, 29 and 46 hours. Each compound of methyl trans-cinnamate derivatives to be performed molecular docking, virtual constructed in the form of two-dimensional (2D) using BKChem application. The simulation molecular docking using PLANTS 1.1. The structure of methyl trans-cinnamate derivatives was characterized by IR, melting point, UV, 1H NMR, 13C NMR, and mass spectral analysis. Results: The result showed that antiinflamatory activity of Na diclofenac, ibuprofen, cinnamic acid, and 3-phenil propionic acid were -20,6 %, -3,7 %, -43,2 %, 27,7 % respectively. These results showed only 3-phenil propionic acid could reduce edema in the rats’ paw. The docking results show that cinnamic acid, 3-phenyl propanoic acid and 3- (4-benzoylphenyl) propanoic acid are predict to have activity as COX-2 inhibitors.
In Vivo Antihypercholesterolemic Effects of Caricapubescens Seeds Hypercholesterolemic-induced Rats Luhurningtyas, Fania Putri; Aprilliana, Melati; Alifa, Gea Ros
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2019: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.1428

Abstract

Background: Carica is a typical plant originating from the Dieng Plateau. Carica processed products leave waste in the form of Carica seeds which have not been utilized. Based on the previous study, Carica seeds contain tannin, flavonoids, and alkaloids, so in this study, Carica seeds extract was used in the antihyperlipidemic study. Objective: To analyze the reduction of total cholesterol and secondary metabolites in the ethanol extract of Carica seeds using thin-layer chromatography.Method:Extraction was carried out by the maceration method using 96% ethanol. Antihypercholesterolemic study used 6 groups of rats Wistar strains consisting of normal group, positive control, negative control, treatment 1 (200 mg / KgBB), treatment 2 (400 mg / KgBB), treatment 3 (600 mg / KgBB). Total cholesterol level tests were carried out by using a biosystem with diasysic reagents. Statistical tests were carried out with one way ANOVA followed by LSD post hoc tests.Result: Carica seed extract has flavonoids and alkaloids. The percentage decrease in cholesterol levels in treatments 1, 2 and 3 was 15% ± 11,619, 24% ± 8,813 and 21% ± 19,471 with a significance value in the one way ANOVA test was 0,000. Conclusion: The dosage variations of Carica seed extract Affects comparable to simvastatin in reducing total cholesterol levels.
The Effect of Rosella (Hibiscus sabdariffa Linn) on Insulin Resistance in Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial Sarbini, Dwi; Huriyati, Emy; Sadewa, Hamim; Wahyuningsih, Mae Sri Hartati
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2019: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.1429

Abstract

Insulin resistance in Type 2 Diabetes Mellitus (T2DM) is indicated with high fasting blood glucose level, fasting insulin and HOMA-IR. The long-time consume of diabetes drugs would bring harm. Rosella can be used as a complementary drug to improve insulin resistance and prevent T2DM complications. This study seeks the effect of consuming Rosella on fasting blood glucose, fasting insulin and HOMAIR in T2DM patients.The study design used double-blinded & placebo-controlled randomized clinical trial with intervention (placebo and Rosella) for 8 weeks. The sample consisted of 52 T2DM outpatients at Health Office Yogyakarta City. Measurement of fasting blood glucose was conducted through GOD-PAP method, fasting insulin was measured by MEIA, HOMA-IR was calculated with HOMA Calculator 2.2.3 Version. Analysis of the influence of Rosella on fasting blood glucose, fasting insulin and HOMA-IR level in one group were tested with the Wilcoxon Signed Test and the effect between groups were tested through Mann Whitney with a significance level of 95%.Rosella consumption can reduce fasting blood glucose, fasting insulin and HOMA-IR levels. There was a significant effect of Rosella administration on decreasing fasting blood glucose level in T2DM patients (p=0.001) but there were no significant effect on decreasing fasting plasma insulin level and HOMA-IR levels (p=0.932 and p=0.368). Rosella can improve insulin resistance by reducing fasting blood glucose levels, fasting insulin levels and HOMA-IR values.
The Immunomodulatory Activities of Saurauia vulcani Korth Leaves towards RAW 264.7 cell Rosidah, R; Yuandani, Y; Widjaja, Sri Suryani; Lubis, Muhammad Fauzan; Satria, Denny
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2019: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.1430

Abstract

Saurauia vulcani Korth is an actinidiaceae family plant that is used as traditional medicine by the community. Testing the immunomodulatory effect of Saurauia vulcani Korth extract was done in vitro on RAW cells line by stratified extraction using n-hexane, ethyl asetat, and ethanol solvents. Determination of nitric oxide levels by the griess method and inhibition of gene expression TNF-α, IL6, COX-2, IL-1β, and iNOS by RT-PCR method. Saurauia vulcani Korth extract (NESVL, EAESVL, and EESVL) at a concentration of 25 ug / ml was able to reduce the value of nitric oxide in RAW cells 246.7 and was able to inhibit the expression of genes TNF-α, IL-6, COX-2, IL-1β, and iNOS. Where the density value of each band formed by 1.21 ± 0.005; 1.15 ± 0.005; 0.88 ± 0.003 on TNF-α, 1.23 ± 0.003; 1.64 ± 0.005; 0.55 ± 0.003 on IL-6, 0.38 ± 0.003; 0.55 ± 0.003; 0.38 ± 0.003 on COX-2, 0.18 ± 0.003; 0.04 ± 0.003; 0.03 ± 0.003 on IL-1β, and 0.30 ± 0.003; 0.41 ± 0.003; 0.11 ± 0.005 on iNOS.
Conversion Eugenol to Vanillin: Evaluation of Antimicrobial Activity Triana, Desita; Tafdila, Muhammad Akbar; Antika, Lucia Dwi; Ernawati, Teni
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2019: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.1431

Abstract

Indonesia is known as one of the largest clove producing countries in the world. About 75-90% main component of the clove oil is eugenol. Eugenol can be used as an analgesic, local anaesthetic, and also recognized as antimicrobial. Eugenol is known as starting material to produce synthetic vanillin. Vanillin is a compound that can be isolated from vanilla (Vanilla p lanifolia) or chemically synthesis. Vanillin is widely used for flavouring, fragrance, and also as a precursor of drugs in the pharmaceutical industry. Conversion eugenol to vanillin through several phases including isomerization, acetylation, oxidation, and hydrolysis. From each phase, it produces intermediate products, there are isoeugenol, isoeugenol acetate, and vanillin acetate, and also produce by-product vanillic acid. This present study aims to evaluate the results from the conversion of eugenol to vanillin for its antimicrobial activity against pathogenic bacteria E. coli and S. aureus. The result showed that eugenol, isoeugenol, vanillin acetate, vanillin and vanillic acid had antimicrobial activity. Isoeugenol which is the result of isomerization of eugenol is known to possess the best antimicrobial activity.

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