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Farmasains : Jurnal Farmasi dan Ilmu Kesehatan
Published by Universitas Muhammadiyah Malang
ISSN : 20863373     EISSN : 2620987X     DOI : 10.22219
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Farmasains publishes articles that cover textual and fieldwork studies with various perspectives of pharmacy science including: Pharmaceutical Technology Pharmaceutical Chemistry Biology Pharmacy and Natural Products Pharmacology and Toxicology Clinical Pharmacy Community Pharmacy Pharmacoepidemiology Pharmacogenomic and Pharmacogenetic Pharmacoeconomic Health-related topics
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 170 Documents
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Analysis of Compound Activities in Cinchona Officinalis as Antiaging With a Computational Approach Esti Mulatsari; esti Mumpuni
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 7 No. 1 (2022)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v7i1.18134

Abstract

Several studies on plants that have antiaging properties have been widely published. From these studies, research has not been carried out on compounds in cinchona plants that may provide efficacy as antiaging. Initially, cinchona is a plant that is famous for its antimalarial properties. But the use of cinchona as an antimalarial has now been reduced so research needs to be done to look for another potential of the cinchona plant. This study aims to conduct a computational approach of compounds derived from cinchona as an inhibitor of the elastase, hyaluronidase, collagenase, and tyrosinase enzymes with oleanolic acid, EGCG, and arbutin as comparative compounds. The method used in this study is molecular docking using YASARA, Marvinsketch, PLANTS, VMD, and statistic R software. From the research results, six (6) candidates of active compounds as elastase enzyme inhibitors, twenty one (21) candidates of the active compound as hyaluronidase enzyme inhibitors, four (4) candidates of the active compound as collagenase enzyme inhibitors, and four (4) candidates of the active compound as tyrosinase inhibitors. Two compounds have potential as antiaging, i.e chlorogenic acid and Cyanidol 3-rhamnoglucoside.
The Formulation and Evaluation of Facial Wash containing Snow Mushroom (Tremella fuciformis) Extract Astridani Rizky Putranti; Krisyanti Budipramana; Mellynia Fortuna Salim
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 7 No. 1 (2022)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v7i1.20063

Abstract

The aims of this study were to determine and evaluate the results of the physicochemical characteristic of snow mushroom (Tremella fuciformis) facial wash, and to determine the acceptability of the snow mushroom (Tremella fuciformis) extract facial wash which has the best physicochemical characteristics. In this study, the extraction of snow mushroom (Tremella fuciformis) used UAE (Ultrasound-Assisted Extraction) and ethanol as solvent with various concentrations, 96% (F1), 75% (F2), and 50% (F3). Furthermore, the extract will be formulated into facial wash and evaluated for physicochemical characteristics. The parameters of physicochemical characteristics include organoleptic, pH, density, viscosity, spreadability, and foamability. The difference in the concentration of ethanol as menstruum of snow fungus (Tremella fuciformis) extraction did not significantly affect the organoleptic composition of facial wash, but it did affect the physicochemical characteristics of facial wash, where higher ethanol concentrations resulted in lower pH, higher density and viscosity, smaller spreadability, and foamability that meets specifications. The results of the evaluation of physicochemical characteristics showed that F1 had the best specifications and continued hedonic testing to determine the acceptability of snow mushroom (Tremella fuciformis) extract facial wash. The results of the hedonic test on F1 showed good acceptance regarding the parameters of appearance, foam, and effects after using facial wash; as well as sufficient acceptability related to aroma and viscosity parameters.
Liposome as Mucosal Vaccine Drug Delivery System Kuni Zuaimah Barikah
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 7 No. 1 (2022)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v7i1.20390

Abstract

Vaccines are a pharmaceutical product that is used to overcome infectious diseases and are a new therapeutic strategy for chronic disease treatment, recently.  However, the parenteral route as the main route of vaccination nowadays has several limitations, so mucosal vaccines rise as a potential alternative for vaccine delivery. A few research found that mucosal vaccines have better immune protection against pathogens.  Liposome, a biodegradable particulate drug delivery system, offers the most promising future as a mucosal vaccine delivery system because of its versatility. A liposome can act as an adjuvant by direct stimulation of immune response in several ways. Several liposome properties that affect system uptake after mucosal administration are size, surface charge, and hydrophilicity. To enhance liposome ability as mucosal vaccine, targeted liposomes, such as mannose receptor-targeted liposome, macrophage galactose-type C-type lectins (MGL) targeted liposome, DC-specific intracellular adhesion molecule-3 grabbing non-integrin (DC-SIGN), and M cells targeted liposome then developed.
The Relationship of Patient Satisfaction with Therapeutic Services with Therapeutic Compliance in Outpatient Hypertension Patients at Wonosari Hospital Dewi Ratih Anggraini
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 7 No. 1 (2022)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v7i1.17327

Abstract

The increasing prevalence of hypertension cases is related to the low level of patient compliance in taking antihypertensive drugs. So, adherence to therapy is an essential element in managing hypertensive patients. One of the efforts to improve patient compliance in the use of drugs is the need for good service quality toprovide satisfaction to patients with the therapeutic services obtained. This study aimed to determine the relationship between satisfaction with therapy services and adherence to therapy in outpatient hypertension patients at Wonosari Hospital. The type and research design used is analytic observational with a cross-sectionalapproach. The number of samples was determined using the Lemeshow formula. The sampling technique used in this study is nonprobability sampling with the purposive sampling method. The sample subjects used in the study were all patients with a primary diagnosis of hypertension who had met the inclusion and exclusioncriteria. The data collected is patient satisfaction with therapy services using the PSQ-18 questionnaire and therapeutic compliance with the MARS-5 questionnaire. The data obtained were then analyzed usingFisher's test. The results showed that of the 96 respondents, 89.6% were satisfied, 10.4% were dissatisfied with the health services obtained at Wonosari Hospital, 61.5% were compliant, and 38.5% were not compliant with their treatment. Fisher's analysis showed a significant relationship between patient satisfaction and adherence totherapy in hypertension patients with p = 0.000 (p <0.05). This study concludes that a meaningful relationship exists between satisfaction with therapy services and adherence to therapy in outpatient hypertension patients at Wonosari Hospital.
Study of Antibacterial Activity of Green Betel Leaf (Piper betle L.) and Red Betel Leaf (Piper Crocatum L.) Extract Against Pseudomonas Aeruginosa Bacteria Nailul Mukafiah
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 7 No. 1 (2022)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v7i1.17379

Abstract

Green betel leaf (Piper betle L.) and red betel leaf (Piper crocatum L.) are plants commonly used for traditional medicine. The betel plant can treat infections. Pseudomonas aeruginosa is a bacteria that causes nosocomial infections. This article's purpose is to describe previous research on the antibacterial activity of green betel leafextract (Piper betle L.) and red betel leaf (Piper crocatum L.) against Pseudomonas aeruginosa bacteria. We used a traditional review. A search in the literature was carried out by entering the keywords: Piper betle L., Piper crocatum L., Pseudomonas aeruginosa, and antibacterial in PubMed, Science Direct, and Google Scholar databases. Data sources were obtained online, then selected based on inclusion criteria, namely in the form of complete articles inIndonesian and English, explaining the extracts of green betel leaf (Piper betle L.) and red betel leaf (Piper crocatum L.) against both Pseudomonas aeruginosa bacteria in single or combination from the years 2008-2021. The search results for articles obtained were 344.122 articles, and 15 articles were included from various countries. The results showed that the extracts of green betel leaf (Piper betel L.) and red betel leaf (Piper crocatum L.) were able toinhibit Pseudomonas aeruginosa bacteria with strong to weak inhibition zones. Betel leaf extract (Piper betle) has been shown to have antibacterial properties and can inhibit Pseudomonas aeruginosa bacteria with strong to weak inhibition zones, single or combination from the years 2008-2021.
The influence of marketing mix and service quality of Puskesmas Bojong Nangka against BPJS patient satisfaction Rahmi, Novi Henriyati; Sampurno, Sampurno; Sumaryono, Wahono
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 7 No. 2 (2022)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v4i2.8840

Abstract

This study aims to analyze how the influence of the service marketing mix in this product, price, promotion, location, people, physical evidence, and the process, and the quality of health services in this case direct evidence (tangibles), reliability, responsiveness, assurance, and empathy at the Puskesmas Bojong Nangka\, Gunung Putri District, Bogor Regency towards patient satisfaction BPJS. The research method used a cross-sectional or cross-sectional descriptive analysis method. The place of research was at the Puskesmas Bojong Nangka, Gunung Putri, Bogor. The research sample amounted to 100 people. Data collection techniques are questionnaires and observations. Analysis of research data is by the Multiple Linear Regression test with Y1 = 1.515 + 0.064X1 + 0.073X2. The study concludes that the marketing mix and the quality of health services affect the satisfaction of BPJS patients in partial and both. Puskesmas quality variables more influence BPJS patient satisfaction compared to service marketing mix variables.
Patient satisfaction with waiting time for outpatient prescription services based on sharia characteristics in the pharmacy installation Prof. Dr. Soerojo Hospital Magelang Arifin Santoso; Ishak; Novia Wulandari
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 8 No. 1 (2023)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v8i1.26060

Abstract

Including pharmaceutical services, service quality improvement must be carried out appropriately, quickly, and with a sense of security. Hospital pharmacy services can be evaluated based on five criteria, namely reliability, responsiveness, assurance, dependability, and empathy. One of the pharmaceutical service factors that must meet the minimum requirements for hospital services is the waiting time for prescription filling. 1) Objective: to assess satisfaction of the duration of the outpatient prescription service wait based on sharia characteristics in RSJ. Prof. Dr. Soerojo Magelang; 2) Methods: descriptively with a cross-sectional design using accidental sampling techniques on questionnaires that were analyzed univariately and bivariately using SPSS; 3) Results: a questionnaire with a total of 30 respondents showed that the patient satisfaction category was very satisfied from the five measurement dimensions (77%, 57%, 73%, 67%, 54%) and satisfied (23%, 43%, 27%, 33% , 46%) with a prescription service wait time not more than 30 minutes for non-concoction and less than 60 minutes for concoction; 4) Conclusion: based on sharia characteristics of the five dimensions of satisfaction, the results are very satisfied and satisfied and the outpatient prescription waiting time service meets the minimum standards of hospital services.
Education on sharia drug use in bipolar disorder patients during fasting month at Prof. dr. Soerojo Mental Hospital Magelang Nadila Prameswari; Arifin Santoso; Ishak
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 8 No. 2 (2023)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v8i2.26127

Abstract

Bipolar disorder is an emotional state or mood that ranges from manic (high) to depressive. The role of the Qur'an in dealing with mental disorders can be as a therapist in changing the mind, personality of the patient gradually, and as a healer for patients suffering from mental disorders. The purpose of this study was to determine the impact of sharia drug use education on bipolar patients at Prof. Dr. Soerojo Magelang Mental Hospital during the fasting month. Methods: This research is a descriptive qualitative research. Data collection for this study was conducted in February-March 2023. This study used a questionnaire as a tool to collect data and information media delivered through brochures. The results showed that bipolar disorder cases mostly had female gender characteristics (52%), and most had high school education (80%) as the last recorded education. With the results of the percentage value of understanding sharia drug use education in bipolar disorder patients, there is an increase in the influence on the success of patient therapy in peace of mind, quality of life and compliance in taking medication.
A Study progress on moringa seed oil with microemulsion: bibliometrics analysis of year 2012-2023 chasanah, Uswatun; Lalu Muhammad Irham; Nining Sugihartini; Sapto Yuliani
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 8 No. 1 (2023)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v8i1.28978

Abstract

Transdermal drug delivery systems increase the effectiveness of a drug substance, and one of them is a microemulsion. Moringa oil has anti-inflammatory, antioxidant, and antibacterial activity. The purpose of this study is to conduct a bibliometric analysis research on moringa oil formulated as microemulsions. A total of 5 English articles from the Scopus databases from 2012 to 2023 US sources were used in the bibliometrics analysis of Moringa oleifera seeds oil related to microemulsions. The bibliometrics analysis shows research trends, including the most used keywords depicted in visualizations using the VOSViewer application, article publishers, affiliations, and the author's country of origin. The most used keywords are microemulsions, microemulsion, Moringa oleifera, antioxidant activities, and antioxidants. The most publishers are Key Engineering Materials, the most affiliated are Chiang Mai University and Thamasat University, and most authors are from Thailand. The study of microemulsion formulations of Moringa seed oil has yet to be widely carried out but has been cited by other researchers.
The relationship between knowledge and perceptions towards acceptance of the COVID-19 vaccine among health students at University of Muhammadiyah Malang Jannah, Annisa Miftahul; Sendi Lia Yunita; Mutiara Titani
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 7 No. 2 (2022)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v7i2.29359

Abstract

Background: COVID-19 (coronavirus disease 2019) is a disease caused by SARS-CoV-2 that attacks the respiratory system. The government has made various prevention efforts, one of which is to create a COVID-19 vaccination program. Objective: to determine the level of knowledge, perceptions, and acceptance of the COVID-19 vaccine, as well as the relationship between the level of knowledge and perceptions towards acceptance of the COVID-19 vaccine among Health Students. Methods: This study is a quantitative study with a cross-sectional study design using online questionnaire. A sample size of 100 respondents was obtained. The relationship between respondent characteristics, knowledge, and perceptions of COVID-19 vaccine acceptance was tested using the Chi-Square and Logistic Regression statistical tests. Results: It was found that 97% of respondents had good knowledge, 61% of respondents had positive perceptions, and 50% of respondents had high acceptance of the COVID-19 vaccine. There is a relationship between respondent gender (p=0.028) and acceptance of the COVID-19 Vaccine. There is a relationship between perception (p=0.000) and acceptance of the COVID-19 vaccine. However, there is no relationship between knowledge (p=0.500) and acceptance of the COVID-19 vaccine. Conclusion: There is a relationship between perception and acceptance of the COVID-19 vaccine.

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