cover
Contact Name
Nailis Syifa
Contact Email
nailissyifa@umm.ac.id
Phone
+6285810289644
Journal Mail Official
farmasains@umm.ac.id
Editorial Address
Jl. Bendungan Sutami No.188, Sumbersari, Kec. Lowokwaru, Kota Malang, Jawa Timur 65145
Location
Kota malang,
Jawa timur
INDONESIA
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan
ISSN : 20863373     EISSN : 2620987X     DOI : 10.22219
Core Subject : Health, Science,
Farmasains publishes articles that cover textual and fieldwork studies with various perspectives of pharmacy science including: Pharmaceutical Technology Pharmaceutical Chemistry Biology Pharmacy and Natural Products Pharmacology and Toxicology Clinical Pharmacy Community Pharmacy Pharmacoepidemiology Pharmacogenomic and Pharmacogenetic Pharmacoeconomic Health-related topics
Articles 170 Documents
Relationship between knowledge and attitude toward travel health preparation behaviour of air travellers during COVID-19 pandemic Alhaque, Nitya Fithra Salsabila; Savitri, Pritha Maya; Muti, Annisa Farida; Hadiwiardjo, Yanti Harjono
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 8 No. 2 (2023)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v8i2.30698

Abstract

COVID-19 is a highly contagious disease. People who travel in this situation, including air travel, can increase the risk of transmitting or being transmitted by COVID-19. The attack rate of COVID-19 during air travel is 4.8%. It is necessary to form a new behaviour regarding good health preparation before travelling to prevent the spread of COVID-19. A person's behaviour can be affected by knowledge and attitude. This research aims to determine the relationship between knowledge and attitude towards the travel health preparation behaviour of air travellers during the COVID-19 pandemic. This research is an observational analytical study with a cross-sectional approach. The population in this study was people who travelled by air from Soekarno-Hatta International Airport during the COVID-19 pandemic, with inclusion sample criteria of people who travelled by air in June – October 2021 and were aged 15–64 years old. The sample was collected using a purposive sampling technique using social media, and 104 respondents were obtained. The data was collected using an online questionnaire via a Google form. The result shows that the majority of respondents have good knowledge (44.2%), a positive attitude (59.6%) and good behaviour (76%). There was no significant relation between knowledge and behaviour (p=0.066) and a significant relation between attitudes and behaviour (p=0.000). This result can be caused by several factors influencing behaviour, such as other predisposing factors (besides knowledge and attitudes), enabling factors, and reinforcing factors, such as easy access to massive information about the COVID-19 pandemic and strict government regulation.
Development microemulsion formulation combination of citronella and red ginger essential oil Chasanah, Uswatun; Wardhani, Ellen Kusuma; Ermawati, Dian
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 8 No. 2 (2023)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v8i2.35039

Abstract

Acne vulgaris is a skin health problem. Citronella oil contains citronellal, geraniol, geranial, β-citronellol, and neral, which have antibacterial properties. Meanwhile, red ginger oil contains gingerol, which has anti-inflammatory properties. These two ingredients are suitable for treating acne vulgaris. The aim of this study are to develop microemulsion formulation combination of citronella and red ginger essential oil. In this experimental study, a microemulsion combination of citronella essential oil and red ginger essential oil was made using Tween 80 as a surfactant and Transcutol® as a co-surfactant, with variations of S-mix (surfactant:cosurfactant) of 3:3, 4:2, and 4.5:1.5 ratios. As an oil carrier, isopropyl myristate is used. The microemulsions are formulated using a titration method. The microemulsion was then tested for characteristics and stability. The results show that the most optimal microemulsion formula was obtained with an S-mix ratio of 4:2 with a globule size of 21.64 nm, a Polydispersion Index of 0.15, and a zeta potential of -3.82. Its pH and viscosity meet the required specifications and are stable.
Level of anxiety and internal tryout evaluation of the national objective structured clinical examinations (OSCE) results for pharmacy students Astuti, Engrid Juni; Hidayati, Ika Ratna
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 7 No. 2 (2022)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v7i2.35340

Abstract

OSCE (Objective Structured Clinical Examination) for pharmacist profession students is currently one of the measuring tools for success in competency exams to test victory in learning the Pharmacist Profession, in addition to the MCQ (Cognitive Based Test) method which is carried out in the form of CBT (Computer Based-Test). The Pharmacist Profession Study Program at the University of Muhammadiyah Malang (UMM) currently has professional pharmacist students and conducted a national tryout test for batch 2 students. In contrast, these students have never received training for the OSCE exam before. This study was conducted to evaluate the internal tryout on the results of the national OSCE score for Pharmacist students at the University of Muhammadiyah Malang” in batch 3 compared to batch 2, which had not done an internal tryout. In addition, an anxiety test was conducted on students taking the OSCE exam to get the degree of anxiety students taking the exam. From the study results, the anxiety level of the 2nd and 3rd batch students when facing the national OSCE exam was moderately anxious. Implementing the internal tryout had significant effects on the passing rate of the 3rd batch of students in the national OSCE exam.
Nano antioxidant serum ethanol extract lime peel (Citrus aurantifolia S.) Fortuna, Putri Asabella; Mugiyanto, Eko; Waznah, Urmatul; Rahmasari, Khusna Santika
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 7 No. 2 (2022)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v7i2.35928

Abstract

Serum is a cosmetic that has received great attention from the industry, but the main challenges are appearance, transparency and public acceptance of herbal active ingredients. On the other hand, herbal cosmetics, such as those using lime peel, are also growing. This study aims to determine the antioxidant activity of lime peel made in a nano extract serum preparation. The method for making nano extracts uses ionic gelation with PSA (Particle Size Analyzer) and Zeta Potential characterization. The concentration of nano serum of lime peel ethanol extract used was 0.5%; 1%; and 3%. Meanwhile, the antioxidant activity testing method uses DPPH and data analysis applied one-way ANOVA then by Tukey test. The results of the nano extract serum formulation using organoleptic testing are transparent, thick and liquid, odorless, and feel moist on the skin. The results of nanoparticle characterization using PSA measurements with three replications were 295.1; 320.3; 385.4 nm and the results of testing the zeta potential of nanoparticles with three replications, namely 3.2; 3.4; 6.0mV. Furthermore, the results of the antioxidant activity test on the basis of the preparation formula are classified as weak (IC50 value of 156.22 μg/mL); Meanwhile, preparation formula with a concentration of 0.5%; 1%; 3% are considered very strong (IC50 value of 46.39 μg/mL; 41.06 μg/mL; 36.27 μg/mL). The results of data analysis consider significance of p value below 0.05. The conclusion is nano lime peel extract meets the requirements and the serum preparation meets the requirements and has antioxidant activity.
Comparison of activity test of ethanol extract and palm root infusion (Arenga pinnata) as an aphrodisiac Rochmat, M. Idhar Khoirul; Mugiyanto, Eko; Waznah, Urmatul; Nur, Achmad Vandian
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 8 No. 2 (2023)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v8i2.36346

Abstract

The palm tree (Arenga pinnata) contains secondary metabolites such as saponins, phenols, triterpenoids, alkaloids, and flavonoids that can be used as medicine, particularly as an aphrodisiac. Aphrodisiacs are natural substances, medications, or herbal supplements that have the potential to increase sexual arousal. The use of herbal aphrodisiac drugs has been increasing year by year in Indonesia. This study aims to determine the aphrodisiac activity of palm root water extract (Arenga pinnata) in test animals (Web Wiester mice). The preparation of the extract begins with the processing of palm roots, which are then made into an infusion of palm root water (Arenga pinnata). The method of making the palm extract uses infusion and maceration techniques. The aphrodisiac potential test was conducted in vivo using 32 Web Wiester mice, which were divided into 5 groups; the dosage was determined by dividing the mice into five groups (positive control, negative control, 0.5 ml infusion, 1 ml infusion, and extract). The characterization of aphrodisiac properties in the extract included testing the libido of mice (Mus musculus). The results showed that the extract test group with a dose of 250 Mg/KgBW had the highest mating retention among the other test groups.
Formulation and test of physical properties of eyeshadow cream with natural dyes of Kasumba turate flower extract (Carthamus tinctorius L.) Lallita; Mohammad Zaky; Hilda Damayanti
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 9 No. 2 (2024)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v9i2.25047

Abstract

Safflower (Carthamus tinctorius L.) contains two natural pigments,, namely yellow carthamin and orange-red carthamin dye which are used as natural dyes. The research aimed to see whether safflower extract could be used as a natural coloring in eyeshadow cream and the physical properties of eyeshadow cream. The 70% ethanol extract of safflower was formulated into lip cream preparations, with varying concentrations of 0% (K-), 1% (F1), 2% (F2), and 3% (F3). Testing the physical properties of the preparation, namely the organoleptic test, homogeneity test, pH test, type of cream test, spread test, spreadability test, viscosity test, and hedonic test. The formulation of the lip cream of safflower extract showed a distinctive smell of orange essence, yellow to brownish yellow color, semi-solid form, homogeneous preparation until the 28th day, easy to apply, had a pH (4.5-7.0), type cream O/W, has a viscosity of 10,000-20,000 cPs and spreadability of 5-7 cm. This study concludes that Safflower extract can be used as a natural dye in Eyeshadow cream preparations and meets the requirements of good physical properties of Eyeshadow cream preparations.  
The relationship between level of knowledge and medication adherence in hypertensive patients at Pal Tiga Pontianak Health Center Nurmainah; Ressi Susanti; Asyah Padhilah Safitri
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 9 No. 2 (2024)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v9i2.34030

Abstract

Patient non-adherence to medication use is one of the barriers to successful treatment of hypertension. One of the factors that can affect adherence is knowledge. This study aims to analyze the relationship between knowledge level and medication adherence in outpatient hypertensive patients at the Pal Tiga Pontianak Health Center. This research method is an analytic observational study using a cross-sectional research design. This research was conducted during January-February 2024 with a total of 112 respondents. Data collection used the Hypertension Knowledge-Level Scale (HK-LS) and Adherence to Refill and Medication Scale (ARMS) questionnaire. The results showed that the characteristics of outpatients at Pal Tiga Pontianak Health Center tended to be female (61.6%), aged >45 years (93.8%), not working (72.3%), minimum education level of high school (58.9%), have a high level of knowledge (76.8%) and high level of adherence (56.3%). Chi-square analysis showed no significant relationship between gender (p=0.243), age (p=0.465), and occupation (p=1.000). Meanwhile, there was a significant relationship between the education level (0.012) and the adherence level with the use of antihypertensive drugs. The relationship obtained between the level of knowledge and adherence of hypertensive patients is p=0.044 (p<0.05). The conclusion of this study is that there is a significant relationship between the knowledge level and the adherence level of hypertensive patients at the Pal Tiga Pontianak Health Center
Evaluation of the mucolytic activity of ethanol extract of Temu Ireng (Curcuma aeruginosa Roxb.) Waznah, Urmatul; Mufrodah, Nely; Wirasti, Wirasti; Mugiyanto, Eko
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 9 No. 2 (2024)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v9i2.34760

Abstract

Curcuma aeruginosa Roxb., known as Temu Ireng, is a species within the Zingiberaceae family that has been empirically noted for its potential as a cough remedy. Temu Ireng contains alkaloids, flavonoids, and saponins, which play crucial roles in mucus liquefaction. This study aims to investigate the mucolytic activity of the ethanol extract of Curcuma aeruginosa Roxb. In this study, we used an experimental method. The extract was obtained via maceration and analyzed in vitro for its ability to reduce the viscosity of bovine intestinal mucus using a digital viscometer. Bovine intestinal mucus was utilized due to its compositional similarity to human mucus. Test sample concentrations of the Temu Ireng extract were 1.0%, 1.5%, and 2.0%, with acetylcysteine serving as the positive control. Mucolytic activity was indicated by a decrease in mucus solution viscosity. The data were analyzed using one-way ANOVA. The results demonstrated a decrease in mucus viscosity for the Temu Ireng extract test solutions, with statistical analysis indicating a significant difference between the negative control and both the positive control and the Temu Ireng extract samples at concentrations of 1.5% and 2.0%, with p-values of 0.032 and 0.030 respectively (p<0.05). The study concludes that the ethanol extract of Curcuma aeruginosa Roxb. exhibits mucolytic activity at concentrations of 1.0%, 1.5%, and 2.0%.
The distribution of the ABO and rhesus blood groups among diabetes mellitus patients in Zintan City, Libya Abubakeer, Adell; Salem, Retaj Ali Salem; Ali, Amira Mohammed Ali; Mohammed, Amani Altaher Mohammed
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 9 No. 2 (2024)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v9i2.35286

Abstract

Numerous studies have explored the potential connection between ABO blood groups and the risk of developing specific illnesses in the literature. This study aimed to examine the distribution of ABO blood and rhesus (Rh) groups among patients with diabetes mellitus (DM) at the Endocrinology and Diabetes Center in Al-Zintan City, Libya. This cross-sectional study took place from October to December 2022, involving 144 blood samples (99 from diabetic patients and 45 from non-diabetic individuals aged 15 to 85 years). Ethical approval and informed consent were obtained from the Endocrinology and Diabetes Center in Al-Zintan, where all laboratory work and statistical analysis using SPSS were conducted. Of the diabetic patients, 46% were male and 53% were female. The test results showed no association between ABO and Rh blood groups in individuals with diabetes mellitus. Among diabetics, the O blood group was most prevalent at 49%, followed by A (34%), B (11%), and AB (5%). Rh+ was more common (n=88) than Rh- (n=11), with no significant difference (p=0.733). Gender distribution also showed no significant difference (p>0.05). The O blood group was more common in females (55.10%) than males (44.90%), and the B blood group was found more often in females (72.73%) than in males (27.27%). This research shows no significant relationship between ABO and Rh blood types and diabetes mellitus occurrence among patients at the endocrinology and diabetes center in Al-Zintan City. Blood group variations do not influence diabetes prevalence or characteristics in this population.
Antidiabetic activity test of infusion combination rosella flower (Hibiscus sabdariffa L.) and cinnamon bark (Cinnamomum burmannii (Nees & T. Nees) Blume) in male mice (Mus musculus) induced by alloxan Chaerul, Rasid; Mercya, Yovita
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 9 No. 2 (2024)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v9i2.36232

Abstract

Diabetes Mellitus (DM) is a disorder of carbohydrate, lipid and protein metabolism which is characterized by increased blood glucose levels. The existence of DM as a public health problem is increasing globally. This experimental research was carried out to determine the activity of a combination of rosella flower infusion and cinnamon bark on blood glucose levels in male mice that had been induced by alloxan. After ensuring that the blood glucose level of the mice was >175 mg/dl, 4 groups were tested, namely test group 1 was given a single rosella flower infusion, test group 2 was given a single cinnamon bark infusion, test group 3 was given a combination of rosella flower infusion and stem bark cinnamon, and the control group were given aqua destillata. Based on the results of the Kruskal-Wallis non-parametric statistical test, it shows a value of p = 0.009 (p £ 0,05), which means there is a difference in the reduction in blood glucose levels between the test groups. Then, to determine the greatest decrease in glucose levels, a Post Hoc test was carried out and the highest mean rank value was obtained (13.00) in the infusion group of the combination of rosella flowers and cinnamon bark, followed by the cinnamon bark infusion group (5.80), and the rosella flower infusion group (5.20).