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Homeostasis: Jurnal Mahasiswa Pendidikan Dokter
Published by Universitas Lambung Mangkurat
ISSN : -     EISSN : 27224333     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health
Homeostasis adalah jurnal yang berisi tulisan yang diangkat dari hasil penelitian yang memiliki fokus dan ruang lingkup di bidang kedokteran dan kesehatan. Tulisan-tulisan yang dimuat bisa dalam bentuk Original Research, Literature Review, ataupun Laporan Kasus. Homeostasis terbit tiga kali setahun pada bulan April, Agustus, dan Desember di setiap tahunnya.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 25 Documents
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HUBUNGAN USIA DENGAN DERAJAT DIFERENSIASI KANKER PAYUDARA PADA WANITA Hasfira, Fairuz Izdihar; Oktaviyanti, Ika Kustiyah; Budiwinata, Winardi; Priyono, Sasongko Hadi; Rosida, Lena
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13219

Abstract

Abstract: Breast cancer is a type of cancer that starts in the breast tissue and spreads to the duct or lobule epithelium. As people age, the incidence of breast cancer rises. The aim of this research is to determine the correlation between age and the level of breast cancer differentiation in female patients at RSUD Ulin Banjarmasin. This study used a cross-sectional technique and an analytical observational research design. Purposive sampling was the method used to collect the samples. A total of 64 breast cancer slides met the inclusion criteria for the sample size. A 95% confidence level was used to evaluate the relationship between the two variables using the chi-square test. People under the age of 40 received grade 1 (8.7%), grade 2 (39.1%) and grade 3 (52.2%), while people beyond the age of 40 received grade 1 (14.6%), grade 2 (63.4%), and grade 3 (22%). The chi-square statistical results suggest p-value=0,047. The results showed a correlation between a woman's age and the degree of breast cancer differentiation at RSUD Ulin Banjarmasin. Keywords: breast cancer, grade, age  Abstrak: Kanker payudara ialah suatu keganasan pada jaringan payudara yang berasal dari epitel duktus ataupun lobulus. Insiden dari kanker payudara meningkat sejalan dengan bertambahnya usia. Derajat diferensiasi ialah ukuran perbandingan sel kanker dengan sel normal yang membantu dalam memprediksi prognosis. Penelitian ini memiliki tujuan untuk mengetahui apakah adanya hubungan antara usia dengan derajat diferensiasi kanker payudara pada wanita. Penelitian ini memakai rancangan penelitian observasional analitik melalui pendekatan cross sectional. Sampel diambil melalui teknik purposive sampling. Sampel yang memenuhi inklusi ialah 64 slide kanker payudara. Hubungan dari kedua variabel dianalisis menggunakan uji chi-square dengan tingkat kepercayaan 95%. Usia ≤40 tahun didapatkan grade 1 (8,7%), grade 2 (39,1%), dan grade 3 (52,2%), sedangkan usia >40 tahun didapatkan grade 1 (14,6%), grade 2 (63,4%), dan grade 3 (22%). Hasil dari statistik chi-square menunjukkan p-value=0,047. Penelitian ini mendapatkan hasil bahwa adanya hubungan antara usia dengan derajat diferensiasi kanker payudara pada wanita di RSUD Ulin Banjarmasin. Kata-kata kunci: kanker payudara, derajat diferensiasi, usia
GAMBARAN HASIL LABORATORIUM PASIEN COVID-19 YANG DIRAWAT DI RSUD ULIN BANJARMASIN PERIODE 2021-2022 Maulidya, Andini Bena; Muthmainah, Noor; Skripsiana, Nika Sterina; Noor, Meitria Syahadatina; Rahmiati, Rahmiati
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13179

Abstract

Abstract: Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The purpose of this study was to determine the description of the laboratory results of COVID-19 patients treated at RSUD Ulin Banjarmasin in 2021-2022. This research was descriptive study by collecting data on medical records of COVID-19 sufferers who were treated and confirmed positive at the RSUD Ulin Banjarmasin for the 2021-2022 period and using a total sampling technique by taking the entire population. The results showed that in 2021 the abnormal laboratory results were segment neutrophilia (62,9%), trunk neutrophilia (99,9%), lymphopenia (57,8%), CRP increased (80,6%) and LDH increased (73,3%). Meanwhile in 2022 the abnormal laboratory results were anemia (71,5%), hemodilution (73,1%), erythropenia (54,9%), neutrophilia segment (60,1%), trunk neutrophilia (100%), lymphopenia (61,7%), CRP increased (73,9%) and LDH increased (70,4%). The average laboratory results for COVID-19 patients in 2021 were male hemoglobin (12,95 gr/dL), female hemoglobin (11,65 gr/dL), male hematocrit (38,73%), female hematocrit (35,38%), male erythrocytes (4,60 x 106 cells/mm3), female erythrocytes (4,22 x 106 cells/mm3), platelets (317.559 cells/mm3), leukocytes (11,250 cells/mm3), neutrophils (75.97%), lymphocytes (15,61%), CRP (58,10 mg/L), LDH (452,26 U/L). Meanwhile, the average in 2022 were male hemoglobin (11,40 gr/dL), female hemoglobin (11,65 gr/dL), male hematocrit (34,40%), female hematocrit (31,70%), male erythrocytes (4,10 x 106 cells/mm3), female erythrocytes (3,78 x 106 cells/mm3), platelets (321,652 cells/mm3), leukocytes (12.870 cells/mm3), neutrophils (75,37%), lymphocytes (14,52%), CRP (70,20 mg/L), LDH (402,36 U/L). The conclusion was that the transition period (2022) showed more variable abnormal laboratory results. Keywords: COVID-19, Laboratory Results, Infectious Disease Abstrak: Coronavirus Disease 2019 (COVID-19) merupakan penyakit menular yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Penelitian ini bertujuan untuk mengetahui gambaran hasil  laboratorium pasien COVID-19 yang dirawat di RSUD Ulin Banjarmasin periode 2021-2022. Penelitian ini merupakan penelitian deskriptif dengan pengambilan data rekam medis penderita COVID-19 yang dirawat dan terkonfirmasi positif di RSUD Ulin Banjarmasin periode 2021-2022 dan menggunakan teknik total sampling dengan cara mengambil seluruh populasi. Hasil penelitian menunjukkan bahwa pada tahun 2021 hasil laboratorium adalah yang abnormal neutrofilia segmen (62,9%), neutrofilia batang (99,9%), limfopenia (57,8%), CRP meningkat (80,6%) dan LDH meningkat (73,3%). Sedangkan tahun 2022 hasil yang abnormal laboratorium adalah anemia (71,5%), hemodilusi (73,1%), eritropenia (54,9%), neutrofilia segmen (60,1%), neutrofilia batang (100%), limfopenia (61,7%), CRP meningkat (73,9%) dan LDH meningkat (70,4%). Rerata hasil laboratorium pasien COVID-19 tahun 2021 yaitu hemoglobin laki-laki (12,95 gr/dL), hemoglobin perempuan (11,65 gr/dL), hematokrit laki-laki (38,73%), hematokrit perempuan (35,38%), eritrosit laki-laki (4,60 x 106 sel/mm3), eritrosit perempuan (4,22 x 106 sel/mm3), trombosit (317.559 sel/mm3), leukosit (11.250 sel/mm3), neutrofil (75,97%), limfosit (15,61%), CRP (58,10 mg/L), LDH (452,26 U/L). Sedangkan rerata tahun 2022 yaitu hemoglobin laki-laki (11,40 gr/dL), hemoglobin perempuan (11,65 gr/dL), hematokrit laki-laki (34,40%), hematokrit perempuan (31,70%), eritrosit laki-laki (4,10 x 106 sel/mm3), eritrosit perempuan (3,78 x 106 sel/mm3), trombosit (321.652 sel/mm3), leukosit (12.870 sel/mm3), neutrofil (75,37%), limfosit (14,52%), CRP (70,20 mg/L), LDH (402,36 U/L). Kesimpulannya adalah pada masa peralihan (2022) menunjukkan lebih banyak variabel hasil laboratorium yang abnormal. Kata-Kata kunci : COVID-19, Hasil Laboratorium, Penyakit Menular
GAMBARAN KUALITAS TIDUR PADA PENDERITA HIPERTENSI DI PUSKESMAS 9 NOPEMBER BANJARMASIN PERIODE OKTOBER 2023 Mawarni, Khairida; Muttaqien, Fauzan; Kaidah, Siti; Darwis, Yulizar; Panghiyangani, Roselina
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13231

Abstract

Abstract: Hypertension is when systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg. Symptoms that patients often experience headaches, shortness of breath, dizziness, stiff neck, and nocturia which disrupt sleep and impact sleep quality, which will affect control of the development of hypertension. The aim of this research was to determine the description of sleep quality in hypertensive patients at the 9 November Banjarmasin Community Health Center for the October 2023 period. The research method used descriptive observational with a cross-sectional approach with a purposive sampling technique of 93 respondents. Data were collected using structured interviews using the Pittsburgh Sleep Quality Index (PSQI) questionnaire, if a score ≤ 5 was good and a score > 5 was bad. Based on research conducted, it was found that of all respondents (93), there were 7 respondents (7.5%) who had good sleep quality and 86 respondents (92.5%) who had poor sleep quality.  Keywords: hypertension, sleep quality, pittsburgh sleep quality index (PSQI). Abstrak: Hipertensi adalah ketika tekanan darah sistolik  ≥ 140 mmHg dan/atau tekanan darah diastol ≥ 90 mmHg. Gejala yang sering dialami sakit kepala, sesak napas, pusing, kaku tengkuk, dan nokturia yang mengganggu tidur dan berdampak pada kualitas tidur dimana hal tersebut akan memengaruhi pengendalian terhadap perkembangan hipertensi. Tujuan dari penelitian ini untuk mengetahui gambaran kualitas tidur pada penderita hipertensi di Puskesmas 9 Nopember Banjarmasin Periode Oktober 2023. Metode penelitian menggunakan observasional deskriptif dengan pendekatan cross-sectional dengan Teknik purposive sampling sebanyak 93 responden. Pengambilan data dengan wawancara terstruktur menggunakan kuesioner Pittsburgh Sleep Quality Index (PSQI), jika skor ≤ 5 baik dan skor > 5 buruk. Berdasarkan penelitian yang dilakukan, didapatkan dari keseluruhan responden (93), terdapat 7 responden (7,5%) memiliki kualitas tidur baik dan 86 responden (92,5%) yang memiliki kualitas tidur buruk. Kata-kata kunci: hipertensi, kualitas tidur, pittsburgh sleep quality indeks (PSQI)
PERBEDAAN GANGGUAN FUNGSI TANGAN DITINJAU BERDASARKAN KARAKTERISTIK PASIEN PASCA STROKE DI POLI REHABILITASI MEDIK RSUD ULIN BANJARMASIN Putri, Aulia Aurora Raflia; Siddik, Muhammad; Sanyoto, Didik Dwi; Hayati, Azka; Fakhrurrazy, Fakhrurrazy
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13214

Abstract

Abstract: Impaired hand function in post-stroke patients due to brain lesions can result in weakness/paralysis. The research aims to determine whether there are differences in hand function disorders in post-stroke patients based on the characteristics of post-stroke patients. This research is an analytical observational study with a cross-sectional approach. Primary data collection took the form of observations of the FMA-UA questionnaire. The study population was post-stroke patients. The number of samples was taken in the period November-December 2023 using purposive sampling technique. The results of the study showed that there were differences in hand function disorders based on Brunstrom stage and dominant side of the hand, while there were no differences based on gender, age, onset, lesion location, history of attacks, comorbidities. and history of therapy in post-stroke patients. The conclusion of this study was that 2 of the 9 patient characteristics were associated with impaired hand function at the Medical Rehabilitation Polytechnic of Ulin Regional Hospital, Banjarmasin. Keywords: hand function disorder, post stroke, FMA-UE. Abstrak: Gangguan fungsi tangan pada pasien pasca stroke karena lesi pada otak bisa mengakibatkan kelemahan/kelumpuhan. Penelitian bertujuan mengetahui apakah terdapat perbedaan gangguan fungsi tangan pada pasien pasca stroke yang ditinjau berdasarkan karakteristik pasien pasca stroke. Metode penelitian yang digunakan adalah analisis observasional dan desain potong lintang. Data yang diambil adalah data primer melalui pengamatan kuesioner FMA-UE. Populasi penelitian adalah pasien pasca stroke. Jumlah sampel diambil periode November-Desember 2023 dengan teknik purposive sampling. Hasil penelitian ini didapatkan perbedaan gangguan fungsi tangan ditinjau berdasarkan stadium brunnstrom dan sisi dominan tangan sedangkan berdasarkan jenis kelamin, usia, onset, letak lesi, riwayat serangan, komorbid, dan riwayat terapi pada pasien pasca stroke tidak terdapat perbedaan. Kesimpulan penelitian ini didapatkan 2 dari 9 karakteristik pasien  yang memiliki hubungan dengan gangguan fungsi tangan di Poli Rehabilitasi Medik RSUD Ulin Banjarmasin. Kata-kata kunci: gangguan fungsi tangan, pasca stroke, FMA-UE
HUBUNGAN FAKTOR PREDISPOSISI DENGAN KETERLAMBATAN BEROBAT PASIEN KANKER PAYUDARA LANJUT LOKAL Juliana, Adies; Budiwinata, Winardi; Oktaviyanti, Ika Kustiyah
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13175

Abstract

Abstract: Breast cancer patients often come to the doctor diagnosed at a locally advanced stage. The cause of delay in treatment is influenced by predisposing factors, namely knowledge, family history, education level, attitude, action to seek health facilities, fear, and family income. The study aimed to analyze the relationship between predisposing factors and the delay in treatment of locally advanced breast cancer patients. The study used an analytic observational method with a cross sectional approach. The study respondents were 51 patients with locally advanced breast cancer who sought treatment at the Oncology Surgery Polyclinic and were recorded in the medical records of RSUD Ulin Banjarmasin for the period January 2020-November 2023. Data were collected based on a questionnaire of predisposing factors for delay in treatment. Data analysis used Fisher's test on SPSS and was said to have a significant relationship if p < 0.05. As a result, the majority of respondents were in the inoperable category 96.1% with poor knowledge (84.3%; p=0.022), low education level (51%; p=1), no family history (56.9%; p=0.5), poor attitude (92.2%; p=0.152), poor action to seek health facilities (90.2%; p=0.188), fear of symptoms (82.4%; p=0.152), and low family income (60.8%; p=1). In conclusion, there was a significant association between knowledge and delay in seeking treatment for locally advanced breast cancer patients. Meanwhile, the level of education, family history, attitude, action to seek health facilities, fear and family income did not have a significant relationship with the delay in treatment of locally advanced breast cancer patients. Keywords: breast cancer, locally advanced, predisposing factor, treatment delay Abstrak: Pasien kanker payudara seringkali datang ke dokter terdiagnosis pada stadium lanjut lokal. Penyebab keterlambatan berobat tersebut dipengaruhi oleh faktor predisposisi, yaitu pengetahuan, riwayat keluarga, tingkat pendidikan, sikap, tindakan mencari fasilitas kesehatan, rasa takut, dan penghasilan keluarga. Penelitian bertujuan menganalisis hubungan faktor predisposisi dengan keterlambatan berobat pasien kanker payudara lanjut lokal. Penelitian menggunakan metode observasional analitik dengan pendekatan cross sectional. Responden penelitian adalah 51 pasien kanker payudara lanjut lokal yang berobat ke Poliklinik Bedah Onkologi dan terdata di rekam medis RSUD Ulin Banjarmasin periode Januari 2020-November 2023. Data dikumpulkan berdasarkan kuesioner dan analisis data menggunakan uji Fisher pada SPSS, dikatakan memiliki hubungan signifikan apabila p < 0,05. Hasilnya, mayoritas responden dalam kategori inoperable 96,1% dengan pengetahuan kurang (84,3%; p=0,022) tingkat pendidikan rendah (51%; p=1), tidak memiliki riwayat keluarga (56,9%; p=0,5), sikap kurang (92,2%; p=0,152), tindakan mencari fasilitas kesehatan kurang (90,2%; p=0,188), takut gejala (82,4%; p=0,152), dan penghasilan keluarga rendah (60,8%; p=1). Kesimpulannya, terdapat hubungan signifikan antara pengetahuan dengan keterlambatan berobat pasien kanker payudara lanjut lokal. Aspek tingkat pendidikan, riwayat keluarga, sikap, tindakan mencari fasilitas kesehatan, rasa takut dan penghasilan keluarga tidak terdapat hubungan signifikan dengan keterlambatan berobat pasien kanker payudara lanjut lokal. Kata-kata kunci: kanker payudara, stadium lanjut lokal, faktor predisposisi, keterlambatan berobat
HUBUNGAN ASUPAN KARBOHIDRAT, LEMAK DAN PROTEIN DENGAN KEJADIAN STUNTING Yunus, Muhammad Alif; Triawanti, Triawanti; Skripsiana, Nika Sterina
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13236

Abstract

Abstract: Stunting is associated with inadequate consumption of carbohydrates, fats, and proteins. The purpose of this research is to establish a correlation between protein, carbohydrate, and lipid consumption and the prevalence of stunting. This study was carried out utilizing analytic observations in conjunction with case control. A total of 168 subjects were selected via stratified random sampling for the research. The data analysis employed a 2x3 table and the Chi Square test. Based on the data analysis conducted using the Chi Square test, the p-values for the carbohydrate and protein intake variables were 0.009 and 0.000, respectively, and 0.234, respectively, for fat intake. These p-values indicate that there is a significant association between carbohydrate and protein intake and the incidence of stunting in Bakumpai District. However, no significant relationship was found between fat intake and the incidence of stunting. Keywords: Stunting, Carbohydrate intake, Fat intake, Protein intake Abstrak: Stunting dikaitkan dengan kurangnya konsumsi karbohidrat, lemak, dan protein. Tujuan penelitian ini adalah untuk mengetahui hubungan konsumsi protein, karbohidrat, dan lipid dengan prevalensi stunting. Penelitian ini dilakukan dengan menggunakan observasi analitik yang dikombinasikan dengan kasus kontrol. Sebanyak 168 subjek dipilih melalui stratified random sampling untuk penelitian ini. Analisis data menggunakan tabel 2x3 dan uji Chi Square. Berdasarkan analisis data yang dilakukan dengan uji Chi Square, diperoleh p-value pada variabel asupan karbohidrat dan protein masing-masing sebesar 0,009 dan 0,000, serta pada variabel asupan lemak sebesar 0,234. Nilai p-value tersebut menunjukkan bahwa terdapat hubungan yang bermakna antara asupan karbohidrat dan protein dengan kejadian stunting di Kecamatan Bakumpai. Namun tidak ditemukan hubungan signifikan antara asupan lemak dengan kejadian stunting. Kata-kata kunci: Stunting, Asupan karbohdirat, Asupan lemak, Asupan protein
GAMBARAN NILAI KEKUATAN HANDGRIP DAN FATIGUE SEVERITY SCALE PADA PASIEN STROKE DI RSUD ULIN BANJARMASIN Simarmata, Imoia Silvia Y.; Hayati, Azka; Asnawati, Asnawati; Arsyiana, Fathia; Pambudi, Pagan
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13220

Abstract

Abstract: Stroke is a disease characterized by focal brain functional problems and occurs for ≥ 24 hours. The symptom that sufferers often experience is hemiparesis of the fingers. The way to minimize hand muscle weakness after a stroke with handgrip rehabilitation. Stroke causes many stroke patients to feel tired. Assess the severity of fatigue using the fatigue severity scale (FSS). This study aims to describe the value of handgrip strength and fatigue severity scale in stroke patients at Ulin Hospital, Banjarmasin. The samples taken were post-stroke patients in the medical rehabilitation section of Ulin Banjarmasin Regional Hospital for the period October-November. This research uses descriptive methods and a cross-sectional design. The results obtained on the strength of the handgrip include the least category based on gender, namely women (right: 9.8 kg, left: 10.5 kg) and based on age, namely the right of early adulthood (0 kg) and the left of the elderly (7.7 kg). On the fatigue severity scale the worst category based on gender is women (44.4) and by age is the late elderly age (45). So this shows that the value of handgrip strength and fatigue severity scale in stroke patients are included in the category of less or worse. Keywords: stroke, handgrip, fatigue severity scale Abstrak: Stroke adalah penyakit yang ditandai adanya masalah fungsional otak fokal dan terjadi selama ≥ 24 jam. Gejala yang sering dirasakan penderitanya adalah hemiparesis jari tangan. Cara mengurangi kelemahan otot tangan setelah serangan stroke adalah dengan rehabilitasi handgrip. Stroke menyebabkan banyak penderita stroke yang merasa lelah. Menilai tingkat keparahan kelelahan menggunakan fatigue severity scale (FSS). Penelitian ini bertujuan untuk menggambarkan nilai kekuatan handgrip dan fatigue severity scale pada pasien stroke di RSUD Ulin Banjarmasin. Sampel yang diambil merupakan pasien pasca stroke di bagian rehabilitasi medik RSUD Ulin Banjarmasin periode Oktober-November. Penelitian ini menggunakan metode deskriptif dan desain cross-sectional. Hasil penelitian yang diperoleh pada kekuatan handgrip termasuk kategori sedikit lebih kurang berdasarkan jenis kelamin yaitu perempuan (sebelah kanan: 9,8 kg, sebelah kiri: 10,5 kg) dan berdasarkan usia yaitu sebelah kanan usia dewasa awal (0 kg) dan sebelah kiri usia manula (7,7 kg). Pada fatigue severity scale kategori sedikit lebih buruk berdasarkan jenis kelamin yaitu perempuan (44,4) dan berdasarkan usia yaitu usia lansia akhir (45). Sehingga hal ini menunjukkan bahwa nilai kekuatan handgrip dan fatigue severity scale pada pasien stroke termasuk dalam kategori kurang ataupun buruk. Kata-kata kunci: stroke, handgrip, fatigue severity scale
KORELASI KADAR MASSA OTOT DAN KUALITAS HIDUP PADA PASIEN YANG MENJALANI HEMODIALISIS RUTIN DI RSUD ULIN BANJARMASIN Ariewardana, Angger; Rudiansyah, Mohammad; Pratiwi, Dewi Indah Noviana; Cahyawati, Wiwit Agung Sri Nur; Marisa, Dona
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13180

Abstract

Abstract: Chronic Kidney Disease (CKD) is defined as kidney damage or a decrease in the gromerular filtration rate that occurs for 3 months or more, manifesting as kidney damage and requiring kidney replacement therapy, namely hemodialysis. CKD sufferers often experience an energy imbalance due to anorexia which increases energy needs while energy reserves are depleted. Muscle mass levels function as bone moving organs. Muscle mass will be measured using the BIA (Bioimpedance Analysis). Low muscle mass is often associated with low quality of life. Quality of life is an assessment of several aspects of life. Hemodialysis therapy will affect quality of life including lack of energy, fatigue and stress. Quality of life can be measured using the SF-36 questionnaire. This study was to regulate the correlation among muscle mass levels and the level of quality of life of routine hemodialysis patients at RSUD Ulin Banjarmasin. The research method uses analytical observational with a cross-sectional approach. The technique for taking subjects was simple random sampling of 60 subjects. Data collection was carried out by direct measurements and interviews of muscle mass levels and quality of life. Data analysis used the Komolgorov-Smirnov normality test and continued with test called Pearson correlation test. The results of data analysis showed a strong significant correlation (p=0.000, r=0.706). The results of the study concluded that muscle mass levels had a significant correlation with the level of quality of life of hemodialysis patients at RSUD Ulin Banjarmasin. Keywords: Muscle mass, quality of life, hemodialysis, BIA (Bioimpedance analysis), questionnaire QOL Short Form-36. Abstrak: Penyakit ginjal kronis (PGK) didefinisikan sebagai kerusakan ginjal atau penurunan laju filtrasi gromerulus yang terjadi selama 3 bulan atau lebih bermanifestasi sebagai kerusakan ginjal dan memerlukan terapi pengganti ginjal yaitu hemodialisis. Penderita PGK sering mengalami ketidakseimbangan energi akibat anoreksia yang meningkatkan kebutuhan energi sementara asupan energi cadangan habis. Kadar massa otot berfungsi sebagai organ penggerak tulang. Massa otot dapat diukur salah satunya dengan menggunakan alat BIA (Bioimpedance analysis). Rendahnya massa otot kerap dihubungkan dengan rendahnya kualitas hidup. Kualitas hidup merupakan penilaian beberapa aspek dalam kehidupan. Terapi hemodialisis akan mempengaruhi kualitas hidup meliputi kekurangan energi, kelelahan, dan stress. Kualitas hidup dapat diukur salah satunya menggunakan kuesioner SF-36. Tujuan penelitian ini adalah untuk mengetahui korelasi kadar massa otot dan kualitas hidup pasien hemodialisis rutin di RSUD Ulin Banjarmasin. Metode penelitian menggunakan observasional analitik dengan pendekatan cross-sectional. Teknik pengambilan subjek dengan simple random sampling sebanyak 60 subjek. Pengambilan data dilakukan dengan pengukuran dan wawancara langsung kadar massa otot dan kualitas hidup. Analisis data menggunakan uji normalitas Komolgorov-Smirnov dan dilanjutkan dengan uji korelasi Pearson. Hasil analisis data terdapat korelasi bermakna kuat (p=0,000, r=0,706). Hasil penelitian menyimpulkan kadar massa otot terdapat korelasi bermakna dengan kualitas hidup pasien hemodialis di RSUD Ulin Banjarmasin. Kata-kata kunci: Massa otot, kualitas hidup, hemodialisis, BIA (bioimpedance analysis), kuesioner QOL Short form-36.
NILAI KOEFISIEN FENOL DAN DAYA HAMBAT KOMBINASI INFUS EKSTRAK DAUN SIRIH (Piper betle Linn) DAN AKAR KUNING (Fibrauera tinctoria Lour) TERHADAP Escherichia coli ATCC 25922 Amalya, Khalida Zikra; Budiarti, Lia Yulia; Biworo, Agung
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13232

Abstract

Abstract: Transmission of infection by Escherichia coli (E.coli) can be prevented with antiseptics such as alcohol. Natural antiseptics in combination dosage forms can produce stronger antibacterial effects. Betel leaves (P.betle) and yellow roots (F.tinctoria) contain antibacterial properties. The aim of this research is to test the effect of a combination of P.betle and F.tinctoria infusion (PB+FT) on E.coli ATCC 25922. This posttest-only with control group design uses the parameters of the phenol coefficient and inhibition zone values. The treatments in the phenol coefficient test were PB+FT, 70% alcohol control, and 5% phenol in serial dilutions of 1:20-1:250. In the inhibition test using PB+FT, concentrations of 6.25%, 12.5%, 25%, 50%, 75% and 100% as well as 70% alcohol and sterile distilled water were used. The results of calculating the average value of the phenol coefficient from PB+FT, obtained a value >1 and control <1. The results of statistical tests showed that the effect in the form of an average inhibition zone was influenced by the concentration of PB+FT. The average inhibition zone of PB+FT75% is not significantly different from 70% alcohol and PB+FT100% produces a very strong inhibition zone. Conclusion, PB+FT infusion produces a strong effect against E.coli. Keywords: Fibrauera tinctoria lour roots, Piper betle Linn leaves, Escherichia coli, phenol coefficient, zone of inhibition Abstrak: Penularan infeksi oleh Escherichia coli (E.coli) dapat decegah dengan antiseptik seperti alkohol. Antiseptik alami pada bentuk sediaan kombinasi dapat menghasilkan efek antibakteri lebih kuat. Daun sirih (P.betle) dan akar kuning (F.tinctoria) memiliki kandungan bersifat antibakteri. Tujuan penelitian ini yaitu menguji efek kombinasi infus P.betle dan F.tinctoria (PB+FT) terhadap E.coli ATCC 25922. Rancangan penelitian posttest-only with control group design ini menggunakan parameter nilai koefisien fenol dan zona hambat. Perlakuan pada uji koefisien fenol yaitu PB+FT, kontrol alkohol 70%, dan fenol 5% pada serial pengenceran 1:20-1:250. Pada uji daya hambat menggunkan PB+FT menggunakan konsentrasi 6,25%, 12,5%, 25%, 50%, 75%, dan 100% serta alkohol 70% dan akuades steril. Hasil perhitungan nilai reta-rata koefisien fenol dari PB+FT, diperoleh nilai >1 dan kontrol <1. Hasil uji statistik, didapatkan efek berupa rata-rata zona hambat dipengaruhi oleh konsentrasi PB+FT. Rerata zona hambat dari PB+FT75% tidak berbeda nyata dengan alkohol 70% dan PB+FT100% menghasilkan zona hambat tergolong sangat kuat. Kesimpulan, infus PB+FT menghasilkan efek yang kuat terhadap E.coli. Kata-kata kunci: akar Fibrauera tinctoria lour, daun Piper betle Linn, Escherichia coli, koefisien fenol, zona hambat.
AKTIVITAS REPELEN EKSTRAK ETANOL DAUN SIRIH MERAH (Piper ornatum) TERHADAP NYAMUK Aedes aegypti Bangsawan, Bucek Ibrahim; Joharman, Joharman; Widyamala, Erida
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13216

Abstract

Abstract: The red betel leaf (Piper ornatum) contains secondary metabolites such as flavonoids, alkaloids, and tannins, which hold potential as repellents. This study aims to examine the repellent activity of the red betel leaf extract (Piper ornatum) against Aedes aegypti mosquitoes. The research design is a true experimental post-test only with a control group, comprising six treatments: extract concentrations of 12.5%, 25%, 50%, and 100%, a negative control (aquadest), and a positive control (DEET 15%). Treatments are applied to the lower arm of the subjects and exposed to mosquitoes for 5 minutes at 0, 60, 120, 180, and 240 minutes. The Shapiro-Wilk and Levene's tests at minutes 0, 60, 120, and 240 showed that the data were not normally distributed and not homogeneous, while at minute 180, the data were normally distributed. Subsequently, the One-Way ANOVA and Kruskall Wallis tests resulted in a p-value of <0.05, suggesting significant differences among treatments. The research findings indicate that at a concentration of 100%, the red betel leaf extract exhibits a repellent efficacy of ≥90% at 0, 60, 120, and 180 minutes. Thus, the red betel leaf extract demonstrates repellent activity at each minute of testing. Keywords: Piper ornatum, red betel leaf, repellent, Aedes aegypti Abstrak: Sirih merah (Piper ornatum) memiliki metabolit sekunder seperti flavonoid, alkaloid, dan tanin yang berpotensi sebagai repelen. Tujuan penelitian ini untuk menganalisis aktivitas repelen ekstrak daun sirih merah (Piper ornatum) terhadap nyamuk Aedes aegypti. Desain penelitiannya adalah eksperimen dengan pascates saja dan kelompok kontrol dengan enam perlakuan yaitu konsentrasi ekstrak 12,5%, 25%, 50%, 100%, kontrol negatif (aquades), dan kontrol positif (DEET 15%). Perlakuan dioleskan pada lengan bawah probandus, dipaparkan selama 5 menit pada nyamuk dimenit ke-0, 60, 120, 180, dan 240. Pada Shapiro-Wilk dan Levene’s dimenit 0, 60, 120, 240 data tidak terdistribusi normal dan homogen, sedangkan menit ke-180 data terdistribusi normal.  kemudian pada One-Way ANOVA dan Kruskall Wallis didapatkan nilai p<0,05 yang disimpulkan terdapat perbedaan signifikan. Hasil penelitian menunjukkan pada konsentrasi 100% memiliki persentase daya tolak ≥90% dimenit pengujian dan ekstrak sirih merah memiliki aktivitas repelen di setiap menit pengujian. Kata-kata kunci: Repelen Piper ornatum, daun sirih merah, Aedes aegypti

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