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INDONESIA
Prominentia Medical Journal
Published by Universitas Ciputra Surabaya
ISSN : 27467856     EISSN : 27465357     DOI : https://doi.org/10.37715/pmj
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Focus and Scope PMJ (Prominentia Medical Journal) is a scientific journal focused on Medicine and Health. PMJ publishes Research Articles, Literature Reviews, and Case Reports that focus on Preventive Medicine and the Prevention of Lifestyle Diseases. Publication Frequency PMJ (Prominentia Medical Journal) is published biannually, in May and November. Open Access Policy PMJ (Prominentia Medical Journal) (ISSN 2746-7856 and e-ISSN 2746-5357) provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Publication Charges PMJ (Prominentia Medical Journal) is a non-profit-oriented publication journal. Therefore, for the publication process, PMJ (Prominentia Medical Journal) charges certain fees, namely: The published processing fee for articles is free of charge. Please make sure that your citation is written in the references and your article is written properly before submitting it to PMJ (Prominentia Medical Journal) Every manuscript submitted is going through a plagiarism scan using Turnitin.
Arjuna Subject : Profesi Kesehatan - Terminologi Medis
Articles 50 Documents
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Pengaruh Penerapan Metode Applied Behavior Analysis (ABA) pada Anak Penyandang Autisme Fredeswinda Rara Widaranti Langga; Eva Pravitasari Nefertiti; Sitti Radhiah; Wahyu Prasasti Mutiadesi
Bahasa Indonesia Vol 4 No 2 (2023): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v4i2.3525

Abstract

Autism or autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficit in social communication and interaction with restricted and repetitive behavior, interest, or activities. The Applied Behavior Analysis (ABA) method is a behavioral approach that has the possibility of improving clinical manifestations in the aspects of social communication and interaction with the behavior of children with autism. This study aims to determine the effect of applying the ABA method in children with autism. This study used a literature review from 20 national journals indexed by SINTA or Garuda and international journals indexed by Scopus or Scimago in the last 5 years, from 2017 to 2022. The results of the journal review conducted found that the application of the ABA method has significant effectiveness in improving various kinds of clinical manifestations in aspects of impaired social communication and interaction with restricted and repetitive behavior in children with autism. This study concludes that the application of the ABA method affects social communication and interaction with the behavior of children with autism.
SEORANG LELAKI DENGAN MORBUS HANSEN TIPE BORDERLINE TUBERKULOID DISERTAI CACAT KUSTA TINGKAT 2 Stefani Nurhadi
Bahasa Indonesia Vol 4 No 2 (2023): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v4i2.4027

Abstract

Leprosy is a chronic granulomatous disease caused by Mycobacterium leprae, which can cause significant disability in patients. Risk factors for leprosy include genetic susceptibility, environmental exposure, and social and economic factors. Diagnosis and classification of leprosy is based on clinical signs, skin examination, and histopathology. Defects arising in leprosy can result from bacilli infiltration of the skin and nerves, as well as from leprosy reactions in the form of acute neuritis. Prevention and treatment of hand and foot defects need to be done early and involve self-care by the patient. A case of MH type BT in a 29-year-old male with grade 2 leprosy was reported based on anamnesis, physical examination and supporting examination. The management given from the skin and genital department was MDT MB package I and vitamins B1 B6 B12 and the medical rehabilitation department consul was given intrinsic muscle stimulation of the hand, range of movement (ROM) exercises, movement, and functional hand. Leprosy treatment aims to break the chain of transmission, cure patients, and prevent disability. The leprosy eradication program involves treatment with a multi-drug treatment (MDT) regimen tailored to the type of disease. Prevention and treatment of disability in leprosy involves physical exercise, protection of hands and feet, and wound and skin care. People with leprosy also need to understand the importance of self-care and avoiding risk factors that can worsen the condition. Leprosy is a disease that can cause significant disability and impairment. Prevention and treatment of disability in leprosy plays an important role in improving the quality of life of patients. Leprosy eradication programs involving MDT treatment have been shown to be effective in reducing disease incidence. Self-care by sufferers through physical exercise, hand and foot protection, and wound and skin care can help prevent more severe disability. A holistic and comprehensive approach is expected to reduce the negative impact of leprosy on sufferers and society.
PERAN RHO KINASE INHIBITOR DALAM PENATALAKSANAAN GLAUKOMA: STUDI PUSTAKA KOMPREHENSIF MEKANISME, EFIKASI DAN EFEK SAMPING Wilson Christianto Khudrati; Evelyn Komaratih; Titiek Ernawati; Maria Jessica Rachman
Bahasa Indonesia Vol 4 No 2 (2023): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v4i2.4110

Abstract

Glaucoma ranks as the second-leading contributor to visual impairment, affecting a population of more than 76 million people worldwide. Glaucoma drugs currently work to reduce intraocular pressure (IOP) by reducing the production of aqueous humor (AH) in the ciliary corpus or increasing the drainage of AH through conventional or uveoscleral-uveovortex pathways. The newest hypotensive eye medicine, the Rho Kinase Inhibitor (ROCK), works to reduce TIO with the ROCK inhibitor. In addition, the use of ROCK inhibitors has been shown to be beneficial in the treatment of glaucoma, corneal endothelial healing, and progressive diabetic retinopathy. Although there is evidence that the use of Rho kinase-related inhibitors can cause conjunctive hyperemia, before the discovery of the ROCK inhibitor, there was no anti-glaucoma drug that could work with the trabecular meshwork targets, so ROCK is a very promising therapy for glaucoma patients as TM is responsible for 75% of the AH flow.
FARMAKOGENOMIK: PENDEKATAN FARMAKOLOGI MENUJU PERSONALISED MEDICINE Jefman Efendi Marzuki HY; Anggi Gayatri
Bahasa Indonesia Vol 4 No 2 (2023): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v4i2.4235

Abstract

One of the factors contributing to patient morbidity and death is variable variability in treatment response. Adverse drug responses (ADRs) or subtherapeutic effects are possible in certain patients during medication administration. The genetic variation is one of the many variables that contribute to this condition. Pharmacogenomics is the study of how genes influence an individual's response to drugs. The goal of pharmacogenomics is to optimise treatment for the patient. It has been established that a number of genes are associated with drug response, which affects both the direct effects of drugs (pharmacodynamics) and their blood levels (pharmacokinetics). Modifications to a medication's pharmacokinetics and pharmacodynamics may result in toxicity or lessen its efficacy. In order to increase the precision of pharmacotherapy techniques, this study aims to elucidate the availability of data on genetic variants that are known to affect medication response.
BIOMARKER PADA LUPUS NEFRITIS Gisela Tania Irwanto; Yuswanto Setyawan
Bahasa Indonesia Vol 4 No 2 (2023): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v4i2.4559

Abstract

Lupus nephritis (LN) continues to be a leading cause of high morbidity and mortality rates in systemic lupus erythematosus (SLE) patients. Kidney biopsy remains the gold standard for diagnosing LN. Several biomarkers have been identified and evaluated, contributing to improvements in the management of LN patients. This literature review summarizes recent relevant literature on biomarkers for the diagnosis, monitoring, and prognosis of LN. These biomarkers are categorized based on their sample sources, namely serum and urine. Both sample sources show significant variations in biomarker data associated with disease activity and histological parameters of LN. Potential biomarker molecules include antibodies, cytokines, chemokines, and adhesion molecules. This literature review provides a general overview and serves as a reference for further research, particularly in advancing the understanding of LN biomarkers in Indonesia. Keywords: systemic lupus erythematosus (SLE), lupus nephritis (LN), biomarkers, serum, urin
PERBANDINGAN EFEKTIVITAS ANTIBAKTERI EKSTRAK BAWANG PUTIH TUNGGAL DAN MAJEMUK TERHADAP Staphylococcus aureus Dewi, Rahajeng Mutia; Sajuni, Sajuni; Ikawaty, Risma; Aditya, Dwi Martha Nur
Bahasa Indonesia Vol 5 No 1 (2024): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v5i1.4232

Abstract

Infectious diseases, particularly those caused by the bacterium Staphylococcus aureus, pose a serious health issue in Indonesia. Strains of this bacterium are resistant to several antibiotics, making treatment challenging. Therefore, the use of herbal medicines such as garlic, which contain antibacterial compounds, has become a popular alternative treatment. This study aims to compare the effectiveness of single bulb garlic (Allium sativum Linn) and multiple bulbs garlic (Allium sativum) extracts as antibacterials against the growth of Staphylococcus aureus. The method used was disc diffusion (Kirby-Bauer) on Mueller-Hinton agar media with the administration of single and multiple bulb garlic extracts at concentrations of 6.25%, 12.5%, 25%, 50%, and 100%. The results of the study show that the single bulb garlic extract significantly outperforms the multiple bulbs garlic extract in terms of effectiveness. The diameter of the inhibition zone at a concentration of 100% single bulb garlic extract is 24.5, while that of the multiple bulb garlic extract is 28.5. Both types of garlic are effective as antibacterials, with the optimal concentration being 100%. However, the antibacterial activity in single bulb garlic is superior to that in multiple bulbs garlic. Therefore, single bulb garlic could serve as an effective alternative treatment.
Perbandingan Daya Ledak Otot Tungkai Antara Rasio Panjang Tungkai Atas dan Bawah > 1 dan < 1 Panditama, Yukta; Subrata, Tanjung; Udiyani, Desak Putu Citra
Bahasa Indonesia Vol 5 No 1 (2024): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v5i1.4320

Abstract

Muscle explosive power is a person's ability to perform explosive activities suddenly and quickly by exerting all the strength in a short time. The explosive power of the leg muscles is influenced by the length of the leg. The purpose of this study was to find out the comparison of leg muscle explosive power between ratio of upper and lower leg length more than 1 and less than 1. The method of this study was using an analytic observational design with a cross-sectional approach. This study was carried out on 50 male Warmadewa University students who participate in basketball extracurriculars. The study data was analyzed by SPSS program. The results were showed as follow: the average of leg muscle explosive power in all subject and in subjects with a leg length ratio more than 1 and less than 1 were 21,62 ± 3,43 cm; 22,02 ± 3,51 cm; and 19,14 ± 1,34 cm respectively. The conclusion could be drawn that the comparison was significant. This study suggests that the selection of basketball players/athletes should be choosen palyers/athletes with an upper and lower leg length ratio of more than 1.
EFEKTIVITAS JIGSAW METHOD PADA PEMBELAJARAN DARING MELALUI FORUM DISKUSI ZOOM DI FAKULTAS KEDOKTERAN UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA fathanaya, Harris; Siregar, Siti Masliana; Yulfi, Hemma; Irma, Fani Ade
Bahasa Indonesia Vol 5 No 1 (2024): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v5i1.4376

Abstract

ABSTRACT During the Coronavirus Disease-2019 (COVID-19) pandemic, the education sector must adapt by switching from face-to-face teaching and learning activities to online. There are various kinds of learning methods used, Many options are switching from teacher-based learning methods to student-based learning, one of them is the jigsaw method. The jigsaw method is considered to be able to trigger cooperative nature towards others and can increase understanding of the lecture materials or issues raised. To find out how the jigsaw method affects online learning through the Zoom discussion forum. This research is an experimental study with pre-test and post-test control group design in physiology class at Faculty of Medicine, University of Muhammadiyah North Sumatra. Data analysis was conducted using SPSS with Mann Whitney test. Which will be used to determine the effectiveness of the jigsaw method in online learning through zoom application. Subjects were 180 students with 90 students in Class A (conventional method) and 90 students in Class B (jigsaw method). There was a greater increase in the mean value of pre-test (56.22) and post-test (79.44) in the jigsaw method class, compared to the mean value of pre-test (30.22) and post-test (54.67) in the conventional class. In this study, the results of the pre-test and post-test on the jigsaw class method were considered more effective than the control class on the Mann-Whitney test with p<0.001. The jigsaw method is proven to be more effective when applied to online learning than conventional learning methods.
VITAMIN D PADA ASMA BRONKIAL Setyawan, Yuswanto
Bahasa Indonesia Vol 5 No 1 (2024): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v5i1.4487

Abstract

Bronchial asthma is a lung disease characterized by reversible airway obstruction both spontaneously and with treatment, characterized by airways inflammation and hyperreactivity to various stimuli. Until now, the most effective treatment for asthma are corticosteroids and β-agonists, while the administration of prophylactic drugs is often less effective and often causes very disturbing side effects. Vitamin D is a group of fat-soluble secosteroids. Vitamin D has functions in modulating neuromuscular function, reducing inflammation and influencing the work of various genes that regulate cell proliferation, differentiation and apoptosis. Research shows that low levels of vitamin D are associated with increased allergy markers and asthma levels. Vitamin D is believed to play a role in asthma by inhibiting respiratory tract smooth muscle proliferation via hyperphosphorylation of the retinoblastoma protein and activation of checkpoint kinase 1 (Chk1). Vitamin D has recently been considered as a treatment for asthma.
INFARK MIOKARD VENTRIKEL KANAN Arga Putra Mangitung, Muhammad; Laksono, Sidhi
Bahasa Indonesia Vol 5 No 1 (2024): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v5i1.4590

Abstract

Right ventricular myocardial infarction (RVMI) is a serious complication of myocardial infarction, in particular inferior infarction. This condition is characterized by impaired blood flow to the right ventricle resulting in ventriculary dysfunction and hemodynamic disorders. Diagnosis of RVMI requires clinical examination, electrocardiography, and echocardiography. The primary management of RVMI is revascularization as soon as possible to restore blood flow and improve ventricular function. The prognosis of RVMI depends on the location and extent of the infarction, with the blockage of the right marginal artery of the proximal artery having a worse prognosis.

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