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Rosalia Niken
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INDONESIA
Prominentia Medical Journal
Published by Universitas Ciputra Surabaya
ISSN : 27467856     EISSN : 27465357     DOI : https://doi.org/10.37715/pmj
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Focus and Scope PMJ (Prominentia Medical Journal) is a scientific journal focused on Medicine and Health. PMJ publishes Research Articles, Literature Reviews, and Case Reports that focus on Preventive Medicine and the Prevention of Lifestyle Diseases. Publication Frequency PMJ (Prominentia Medical Journal) is published biannually, in May and November. Open Access Policy PMJ (Prominentia Medical Journal) (ISSN 2746-7856 and e-ISSN 2746-5357) provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Publication Charges PMJ (Prominentia Medical Journal) is a non-profit-oriented publication journal. Therefore, for the publication process, PMJ (Prominentia Medical Journal) charges certain fees, namely: The published processing fee for articles is free of charge. Please make sure that your citation is written in the references and your article is written properly before submitting it to PMJ (Prominentia Medical Journal) Every manuscript submitted is going through a plagiarism scan using Turnitin.
Arjuna Subject : Profesi Kesehatan - Terminologi Medis
Articles 55 Documents
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Analisis Hubungan Pola Menstruasi dan Pengetahuan Remaja Terhadap Kejadian Anemia pada Remaja Putri di SMA Darut Taqwa Purwosari Tahun 2024 Sari, Cindy Clara; Tabita Hasianna Silitonga, Hanna; Lewi Santoso, Jemima; Ritunga, Imelda; Charles Pardomuan Tua Siahaan, Salmon
Bahasa Indonesia Vol 6 No 2 (2025): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v6i2.5710

Abstract

Anemia is a significant public health issue in Indonesia, particularly iron deficiency anemia, which has a relatively high prevalence among adolescent girls. Various factors can contribute to this condition, one of which is an irregular menstrual cycle. A deeper understanding of the contributing factors of anemia is essential for adolescent girls in order to prevent this condition. The aim of this study was to determine the correlation between menstrual patterns (frequency, cycle, and duration) and the occurrence of anemia. This research employed a quantitative analytic observational design with a cross-sectional approach. The study was conducted at SMA Darut Taqwa Purwosari. The sample size was determined using the Slovin formula and a simple random sampling technique, resulting in 253 female students as participants. Data collection was performed using the Fora 6 Plus device to measure hemoglobin levels, and a questionnaire to assess the respondents’ menstrual cycles. Data analyses were processed using SPSS software with the Chi-square test. The results showed that 39.1% of students experienced anemia, 32.8% had increased menstrual volume, 38.7% had prolonged menstrual cycles, and 48.2% had extended menstrual duration. The Chi-square test revealed a significant relationship between menstrual patterns (volume, cycle, and duration) and the incidence of anemia with a p-value < 0.001. The study concludes that there is a significant correlation between menstrual patterns and the occurrence of anemia among adolescent girls at the study site.
Pengaruh Ekstrak Kulit Manggis Terhadap Histologi Jumlah Sel Nekrosis Pulau Langerhans Tikus Putih Jantan Hiperglikemik Lewi Santoso, Anna; Lewi Santoso, Jemima
Bahasa Indonesia Vol 6 No 2 (2025): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v6i2.6012

Abstract

The aim of this study was to analyze the histological profile of necrotic cell counts in the islets of Langerhans in hyperglycemic male white rats given mangosteen peel extract. Hyperglycemic conditions can form reactive oxygen species (ROS)/free radicals. Excessive ROS can cause oxidative stress and exacerbate cell necrosis in the islets of Langerhans. Mangosteen peel contains the antioxidant compound, Xanthone, an organic compound derived from diphenyl-γ-pyrone that can neutralize ROS and inhibit islet cell necrosis. This study employed a randomized post-test-only control group design. Four groups of male white rats: the untreated group (normal), the alloxan-induced group, the 250, and 500 mg/kgBW dose groups. The data results were tested using Kruskal-Wallis. The results of the study indicated that mangosteen peel extract had an effect on the histological profile of necrotic cell counts in the islets of Langerhans in male white rats experiencing hyperglycemia; with the number of necrotic cells decreased, the mangosteen peel extract dose of 250 mg was 19.2, and the dose of 500 mg was 18.4. Mangosteen peel extract had an effect on necrotic cells in the islets of Langerhans
Laporan Kasus: Prolaps Uterus Banjarnahor, Dharma Putra Perjuangan; Viena, Windi Clara; Monica, Tasya; Ulhaq, Aura Dhiya
Bahasa Indonesia Vol 6 No 2 (2025): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v6i2.6022

Abstract

Uterine prolapse is a condition in which the uterus protrudes into or outside the vagina. The prevalence of uterine prolapse is 50% in women who have given birth. Uterine prolapse is a spectrum of POP (Pelvic Organ Prolapse), characterized by uterine herniation or prolapse into the vagina due to the weakening of the pelvic floor muscles and other supportive tissues, such as ligaments and fascia. Several risk factors, such as aging, increased intra-abdominal pressure, or multiparity, can contribute to this condition. Diagnosis can be made using the Pelvic Organ Prolapse Quantification (POP-Q) system. Effective treatment needs early prevention through pelvic floor muscle exercise, as well as therapeutic options, including pessary ring use and surgery intervention. Uterine prolapse is not life-threatening, but it may cause significant morbidity and negatively impact the patient’s quality of life, both physically and psychologycally. This study described the case report of a 57-year old woman (P3A0) with a primary complaint of a protruding vaginal mass for the past 3 years. Based on the history and physical examination, the patient was diagnosed with stage 3 uterine prolapse. The inspection indicated a history of pessary therapy without improvement of subjective complaints. The patient was hospitalized and scheduled for a  total transvaginal hysterectomy with anterior and posterior colporrhaphy. The clinical prognosis following total transvaginal hysterectomy was favorable, with improvement in functional outcomes, resolution of prolapse symptoms, improved quality of life, and reduced risk of recurrence in postmenopausal women.
Karakteristik Luaran Kehamilan Pada Pasien Diabetes Dalam Kehamilan Di Rumah Sakit Tersier Indonesia Iftinan, Alisia Nuwayyarotul; Novida, Hermina; Sa'adi, Ashon; Wironegoro, Rio
Bahasa Indonesia Vol 6 No 2 (2025): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diabetes dalam kehamilan merupakan salah satu masalah kesehatan yang dapat meningkatkan risiko morbiditas dan mortalitas maternal maupun perinatal. Penelitian ini bertujuan untuk mengetahui luaran persalinan pada pasien dengan diabetes dalam kehamilan di RSUD Dr. Soetomo, Surabaya, pada periode Januari–Desember 2023. Penelitian ini menggunakan desain deskriptif retrospektif dengan pengambilan data dari rekam medis pasien yang memenuhi kriteria inklusi. Variabel yang dikaji meliputi karakteristik luaran berupa cara persalinan, usia kehamilan, dan berat badan lahir bayi. Dari 97 pasien dengan diabetes dalam kehamilan, terdapat 86 pasien dengan Diabetes Melitus Gestasional (DMG) dan 11 pasien dengan Diabetes Melitus Pregestasional (DMP). Sebagian besar pasien menjalani persalinan melalui sectio caesarea, dengan total 75 kasus (77,3%), sedangkan 22 pasien (22,7%) melahirkan secara spontan. Dibandingkan DMG, kelompok DMP lebih sering menjalani sectio caesarea (90,9%). Hasil ini menunjukkan bahwa pada populasi penelitian terdapat proporsi yang cukup tinggi untuk persalinan caesar, dan kelahiran prematur. Pemantauan ketat kadar glukosa darah dan penatalaksanaan komprehensif sejak awal kehamilan diperlukan untuk meminimalkan risiko terjadinya komplikasi pada ibu dan bayi.
Efektivitas Penggunaan Hidrogel Kratom Terhadap Kadar Gula Darah Pada Ulkus Diabetikum Rihhadatulays, Khuzaimah Nur Juhanifah; Pramesti, Rosandhy Alifyah; Hanafi, Eka Satria Akbar Ferdinan; Jazuli, Muhammad Aqil Siroj; Salim, Hotimah Masdan; Amani, Fariska Zata; Aisyah, Aisyah
Bahasa Indonesia Vol 6 No 2 (2025): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v6i2.6076

Abstract

Type 2 diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia resulting from insulin resistance and pancreatic β-cell dysfunction. One of the most common complications is diabetic ulcers, which are often associated with vascular impairment, infection, and poor glucose stability. The search for alternative therapies continues to develop, including the use of Mitragyna speciosa (kratom) leaves, which contain mitragynine and flavonoids that have been shown to inhibit α-glucosidase and enhance antioxidant activity. This study aimed to evaluate the effect of kratom hydrogel on blood glucose levels in an animal model of diabetic ulcers. Using a posttest-only control group design, mice (Mus musculus) were induced with streptozotocin to establish a type 2 diabetes model. The animals were divided into three groups: positive control, 5% kratom hydrogel, and 15% kratom hydrogel. Blood glucose levels were measured weekly over a two-week period. Data were analyzed using the Kruskal–Wallis test followed by Dunn’s multiple comparison test. The results showed differences in blood glucose levels among all treatment groups. The 15% kratom hydrogel group demonstrated a significant reduction in blood glucose, approaching near-normal levels compared with the positive control (p < 0.05). Statistical analysis indicated a more dominant effect compared to the variation of treatment types. These findings suggest a synergistic mechanism through α-glucosidase inhibition and enhanced antioxidant activity. Therefore, kratom hydrogel has potential as a complementary therapy for glycemic control in patients with type 2 diabetes mellitus complicated by diabetic ulcers.

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