cover
Contact Name
Siska Telly Pratiwi
Contact Email
amhs@fk.unjani.ac.id
Phone
+6281322585754
Journal Mail Official
amhs@fk.unjani.ac.id
Editorial Address
Faculty of Medicine University Jenderal Ahmad Yani Jl. Terusan Jend.Sudirman PO BOX 148 Cimahi.
Location
Kota cimahi,
Jawa barat
INDONESIA
Acta Medical and Health Sciences (AMHS)
ISSN : 28305531     EISSN : 28305426     DOI : https://doi.org/10.35990
Core Subject : Health, Science,
Acta Medical and Health Sciences (AMHS) is a scientific journal that publishes research articles, case reports, literature reviews, and other topics relevant to the field of medicine and health, either clinically or to the biomolecular level. Manuscript under consideration that may be uploaded is a full text of article which has not been published in other national magazines. AMHS is published three times a year (every February, June, and October).
Articles 60 Documents
Hepatoprotective effect of Cinnamon (Cinnamomum burmanii) extract on Serum Aspartate Transaminase (AST) of male wistar rats induced with isoniazid Sovia, Evi; Kristiana, Ris; Nurdina, Salsabila; Rachman, Hidayatul
ACTA Medical Health Sciences Vol. 2 No. 3 (2024): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Hepatotoxicity is a condition of liver cell damage that is often caused by drugs such as isoniazid. Isoniazid (INH) is an anti-tuberculosis drug that, when used excessively, can cause an increase in Reactive Oxygen Species (ROS) and trigger oxidative stress, thereby inducing cell necrosis, especially in the liver. Cinnamon is a plant that contains flavonoids, tannins, alkaloids, and essential oils, which are useful as antioxidants and have the potential hepatoprotective properties. This study aims to determine the effect of ethanol extract of cinnamo n (Cinnamomum burmanii) and its effective dose as hepatoprotection on aspartate transaminase (AST) levels in isoniazid-induced male rats. Extract preparation was carried out using the maceration method. This study was a post-test only control group design laboratory experiment with a sample of 25 male Wistar rats consisting of five groups: the normal control group was given aquabidest (K1), the positive control was induced with 200 mg/kg isoniazid (K2), and three treatment groups were induced with 200 mg/kg isoniazid and given cinnamon ethanol extract at a dose of 100 mg/kg BW, 200 mg/kg BW and 400mg/kg BW for 14 days. At the end of the study, the AST levels were measured. Data were analyzed using the One -Way Anova test and the Tukey's Post Hoc Test. The results showed that the ALT levels of the group given cinnamon at doses of 100, 200, and 400 mg/kg decreased significantly (p<0.05) by 93,20 ± 8,55, 85,60 ± 8,23, and 71,20 ± 3,56 U/L, respectively. The cinnamon ethanol extract could prevent increases in isoniazid-induced AST in rats, thus having a hepatoprotective activity. DOI : 10.35990/amhs.v2n3.p109-115 REFERENCES Lei, S., Gu, R., & Ma, X. (2021). Clinical perspectives of isoniazid-induced liver injury. Liver Research, 5(2), 45–52. https://doi.org/10.1016/j.livres.2021.02.001 Juliarta, I. G., Mulyantari, N. K., & Yasa, I. W. P. S. (2018). Gambaran hepatotoksisitas (ALT/AST) penggunaan obat antituberkulosis lini pertama dalam pengobatan pasien tuberkulosis paru rawat inap di RSUP Sanglah Denpasar tahun 2014. E-Jurnal Medika, 7(10), 1–10. Banjuradja, I., & Singh, G. (2020). Mekanisme hepatotoksisitas dan tatalaksana tuberkulosis pada gangguan hati. Indonesian Journal of Chest, 7(2), 55–64. Sumantri, A. F., Djumhana, A., Wisaksana, R., & Sumantri, R. (2015). Insidensi dan karakteristik hepatotoksisitas obat antituberkulosis pada penderita tuberkulosis dengan dan tanpa infeksi HIV. Global Medical and Health Communication, 3(2), 78. https://doi.org/10.29313/gmhc.v3i2.1548 Santoso, S. B., Chabibah, P. U., & Pribadi, P. (2021). Hepatotoxicity risk profile of Indonesian due to polymorphism of NAT2 and CYP2E1 in isoniazid metabolism. Urecol Journal Part D: Applied Science, 1(1), 9–16. Wang, P., Pradhan, K., Zhong, X. B., & Ma, X. (2016). Isoniazid metabolism and hepatotoxicity. Acta Pharmaceutica Sinica B, 6(5), 384–392. https://doi.org/10.1016/j.apsb.2016.07.014 Nahid, P., & Hopewell, P. C. (2016). Tuberculosis treatment. In International Encyclopedia of Public Health (Vol. 43(5), pp. 267–276). https://doi.org/10.1016/B978-0-12-803678-5.00473-2 Błaszczyk, N., Rosiak, A., & Kałużna-Czaplińska, J. (2021). The potential role of cinnamon in human health. Forests, 12(5), 1–17. https://doi.org/10.3390/f12050648 Rasydy, L. O. A., Supriyanta, J., & Novita, D. (2019). Formulasi ekstrak etanol 96% daun sirih hijau (Piper betle L.) dalam bedak tabur anti jerawat dan uji aktivitas antiacne terhadap Staphylococcus aureus. Jurnal Farmagazine, 6(2), 18. https://doi.org/10.47653/farm.v6i2.142 Rahayu, L., Yantih, N., & Supomo, Y. (2018). Analisis SGPT dan SGOT pada tikus yang diinduksi isoniazid untuk penentuan dosis dan karakteristik hepatoprotektif air buah nanas (Ananas comosus L. Merr) mentah. Jurnal Ilmu Kefarmasian Indonesia, 16(1), 100–106. Ifeanyi, O. E. (2018). A review on free radicals and antioxidants. International Journal of Current Research in Medical Sciences, 4(2), 123–133. https://doi.org/10.2174/22123989oteznmziwtcvy Singh, D., Cho, W. C., & Upadhyay, G. (2016). Drug-induced liver toxicity and prevention by herbal antioxidants: An overview. Frontiers in Physiology, 6(JAN), 1–18. https://doi.org/10.3389/fphys.2015.00363 Metushi, I., Uetrecht, J., & Phillips, E. (2016). Mechanism of isoniazid-induced hepatotoxicity: Then and now. British Journal of Clinical Pharmacology, 81(6), 1030–1036. https://doi.org/10.1111/bcp.12885 Maliangkay, O. J., Assa, Y., & Tiho, M. (2020). Kadar serum glutamic oxaloacetic transaminase (SGOT) pada peminum minuman beralkohol di Kelurahan Tosuraya Selatan. Jurnal e-Biomedik, 8(1), 120–126. Rafita, I. D., Lisdiana, & Marianti, A. (2016). Pengaruh ekstrak kayu manis terhadap gambaran histopatologi dan kadar SGOT-SGPT hepar tikus yang diinduksi parasetamol. Life Science, 4(1), 29–37. Antasionasti, I. J. (2021). Aktivitas antioksidan ekstrak etanol kayu manis (Cinnamomum burmani) secara in vitro. Jurnal Farmasi Udayana, 10(1), 38. https://doi.org/10.24843/jfu.2021.v10.i01.p05 Panche, A. N., Diwan, A. D., & Chandra, S. R. (2016). Flavonoids: An overview. Journal of Nutritional Science, 5(e47), 1–15. https://doi.org/10.1017/jns.2016.41 Hanifa, D. D., & Hendriani, R. (2016). Tanaman herbal yang memiliki aktivitas hepatoprotektor. Farmaka, 14(4), 43–51. Lestari, T., Lubis, Y. M., Nasution, S. W., et al. (2019). Uji efektivitas ekstrak buah kurma (Phoenix dactylifera) dan ekstrak buah mahkota dewa (Phaleria macrocarpa) sebagai nefroprotektor terhadap tikus yang diinduksi paracetamol. Jurnal Farmasi, 1(1), 8–15. Lagarde, F., Beausoleil, C., Belcher, S. M., et al. (2015). Non-monotonic dose-response relationships and endocrine disruptors: A qualitative method of assessment. Environmental Health, 14(1), 13. https://doi.org/10.1186/1476-069X-14-13
Analisis RASCH untuk menganalisis instrumen penilaian kecemasan pada ibu nifas Gumilang, Lani; Linasari, Desy
ACTA Medical Health Sciences Vol. 2 No. 3 (2024): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Globally, an estimated 20% of women who give birth experience postpartum anxiety. Women, after childbirth, require both physical and psychological adaptation. If not treated immediately, postpartum mothers can experience different levels of anxiety. Anxiety in postpartum mothers can harm both mother and baby. Therefore, health workers need to detect anxiety immediately. This assessment (Postpartum Specific Anxiety Scale), or PSAS, helps health workers assess anxiety in postpartum mothers starting from the beginning of the puerperium. However, this measuring instrument needs to be evaluated to assess its use. A Rasch analysis is needed to accurately picture postpartum maternal anxiety. It is considered to have the ability to enhance the accuracy of statistical analysis results and increase measurement precision. This research aims to analyze the postpartum maternal anxiety assessment instrument using Rasch analysis. This study used a descriptive method with a cross-sectional research design involving 36 spontaneous postpartum mothers. The Postpartum Specific Anxiety Scale (PSAS) is the instrument used in this study. According to the results of analysis using the Winsteps program, it is known that there are 34 out of 51 items that meet the item-model accuracy index, with an alpha coefficient of 0.94. The instrument’s separation item index has a value of 3.06. The unexplained variance value does not exceed 15%, so this instrument is ideal for use. Overall, it can be concluded that the anxiety assessment scale for postpartum mothers, namely PSAS, has good psychometric properties for assessment and research. DOI : 10.35990/amhs.v2n3.p138-147 REFERENCES Ministry of Health. Indonesian Basic Health Research Result Report. 2013. Jakarta: Ministry of Health. Oktafia R, Berliyanti AE, Indriastuti AN, Rahmayanti R. Infant Temperament with Anxiety in Postpartum Mothers in Primary Health Care Sleman, Indonesia. Bali Medical Journal. 2023;12(1):451-455. doi: 10.15562/bmj.v12i1.36993. World Health Organization. Maternal Mortality. Geneva: Department of Reproductive Health and Research, WHO; 2023. Zappas PM, Becker K, Moss WB. Postpartum Anxiety. The Journal for Nurse Practitioners. 2020:1-5. https://doi.org/10.1016/j.nurpra.2020.08.017. Rees S, Channon S, Waters SC. The Impact of Maternal Prenatal and Postnatal Anxiety on Children's Emotional Problems: A Systematic Review. European Child & Adolescent Psychiatry. 2018;28:257-280. https://doi.org/10.1007/s00787-018-1173-5. Nagel M, Emily et al. Maternal Psychological Distress and Lactation and Breastfeeding Outcome: A Narrative Review. Department of Health and Human Services-USA. 2022;44(2):215-227. doi: 10.1016/j.clinthera.2021.11.007. Fernandez-Vaz C, Gonzalez-Sanz JD. Cortisol, Maternal Stress, and Breastfeeding Rate at Hospital Discharge: A Systematic Review. Breastfeed Med. 2022;12:984-993. https://doi.org/10.1089/bfm.2022.0165. Carrega J, Lee SY, Clark P, Cranford J, Lloyd S. Impact of the Quality of Postpartum Sleep and Its Health Determinants on Human Milk Volume. MCN Am J Matern Child Nurs. 2020;45(5):289-295. doi:10.1097/NMC.0000000000000645. Bywater T, et al. The Measurement Properties and Acceptability of a New Parent-Infant Bonding Tool (Me and My Baby) for Use in United Kingdom Universal Healthcare Setting: A Psychometric, Cross-Sectional Study. Front Psychol. 2022;14(13):804885. doi:10.3389/fpsyg.2022.804885. Aljaberi et al. Rasch Modelling and Multilevel Confirmatory Factor Analysis for the Usability of The Impact of Event Scale-Revised (IES-R) During the Covid-19 Pandemic. Healthcare (Basel). 2022;10(10):1858. doi:10.3390/healthcare10101858. John M. Linacre. A User's Guide to WINSTEPS®MINISTEP Rasch-Model Computer Programs. 2023. ISBN: 0-941938-03-4. Fallon V, Davies M, Christiansen P, Harrold AJ, Silverio AS. The Postpartum Specific Anxiety Scale: Confirmatory Factor Analyses and Relationships with Birth Experience. Archives of Women's Mental Health. 2022;25:655-65. https://doi.org/10.1007/s00737-022-01233-9. Nielsen MG, et al. The Construct Validity of The Perceived Stress Scale. J Psychosom Res. 2016;84:22-30. doi:10.1016/j.jpsychores.2016.03.009. Allison C, Baron-Cohen S, Stone MH, Muncer SJ. Rasch Modelling and Confirmatory Factor Analysis of The Systemizing Quotient-Revised (SQ-R) Scale. Span J Psychol. 2015;30(18):E16. doi:10.1017/sjp.2015.19. Lee DG, Sohn H, Bae BH, Song Y. Validity of the Breakup Strategies Questionnaire in Korea: Exploratory Structural Equation Modeling and Rasch's Modeling. Psychol Rep. 2018;121(1):163-183. doi:10.1177/0033294117720936. Kurnianto A, Sunjaya KD, Rinawan RF, Hilmanto D. Validation and Reliability of Lifestyle Instruments for Indonesian Adolescents with Hypertension Family History: A Rasch Model. Macedonian Journal of Medical Sciences. 2023;11(B):109-14. https://doi.org/10.3889/oamjms.2023.11127. Silverio Sergio A, et al. A Validation of the Postpartum Specific Anxiety Scale 12 Item Research Short-Form for Use During Global Crises with Five Translations. BMC Pregnancy and Childbirth. 2021;21:112. https://doi.org/10.1186/s12884-021-03597-9. Wijayanto F, Bucur IG, Mul K, Groot P, Van Engelen BGM, Heskes T. Semi-Automated Rasch Analysis with Differential Item Functioning. Behav Res Methods. 2022. doi:10.3758/s13428-022-01947-9. Gondodiputro S, Wiwaha G, Lionthina M, Sunjaya KD. Reliability and Validity of the Indonesian Version of the World Health Organization Quality of Life-Old (WHOQOL-OLD): A Rasch Modeling. Medical Journal of Indonesia. 2021;30(2):143-51. https://doi.org/10.13181/mji.oa.215065. Hilfi Lukman, et al. Rasch Model Analysis of the Indonesian Version of the World Health Organization Disability Assessment Schedule (WHODAS 2.0). The Kitakanto Medical Journal. 2021;71:275-88. doi:10.2974/kmj.71.275. Packham T, MacDermid JC, Selles RW, Slijper HP, Wouters R. Rasch Analysis of the Michigan Hand Questionnaire. Value Health. 2022;25(4):638-646. doi:10.1016/j.jval.2021.09.015. Amiri SM, et al. Psychometric Evaluation of the Postpartum Specific Anxiety Scale-Research Short-Form Among Iranian Women (PSAS-IR-RSF). BMC Pregnancy and Childbirth. 2023;23:531. https://doi.org/10.1186/s12884-023-05855-4. Slomian J, Honvo G, Emonts P, Reginster JY, Bruyere O. Consequences of Maternal Postpartum Depression: A Systematic Review of Maternal and Infant Outcomes. Women's Health. 2019;15:1-55. doi:10.1177/1745506519844044. Davies SM, Christiansen P, Harrold AJ, Silverio SA, Fallon V. Creation and Validation of the Postpartum Specific Anxiety Scale (PSAS). Arch Womens Ment Health. 2021;24(6):957-69. Okunola TO, Awoleke JO, Olofinbiyi B, Rosiji B, Omoya S, Olubiyi AO. Postnatal Blues: A Mirage or Reality. J Affect Disord Reports. 2021;6:100237. Available from: https://doi.org/10.1016/j.jadr.2021.100237. Wulandari RP, Mufdlilah M. Demographic and Obstetric Factors Influencing Postpartum Quality of Life. Journal Obstetrics. 2020;9(2):129.
Level of menarche anxiety before and after adolescent reproductive health education in SDN 19 Lahat Students Rosa Gunadi, Helmi; Soenggono, Arifin; Mutmaini, Silsa
ACTA Medical Health Sciences Vol. 2 No. 3 (2024): ACTA Medical Health Sciences
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Abstract

Women menstruate at varying ages, making it difficult for adolescent girls to describe what is going on with their bodies. They are unprepared and unable to manage their menstruation appropriately due to the limited source of information they receive. As a result, teenage girls experience anxiety symptoms such as fear, anxiety, and discomfort. Anxiety can be decreased by giving the female students sufficient education associated with reproductive health prior to menarche via video media, presentations, discussions, and questions and answers. In this study, an experimental strategy was being used, with a pre-experimental design and a pretest and posttest one-group design. Because the study was conducted on variables for which no data was available, the process had to be modified by providing particular treatments to the research subjects, which were then observed and measured. Before the intervention, it was known that 22 respondents (58%) were not anxious, 4 respondents (11%) had mild anxiety, 7 respondents (18%) had moderate anxiety, 5 respondents (13%) had severe anxiety, and there were no respondents with very severe anxiety. Following the health education intervention, it was observed that 25 respondents (66%) had no anxiety, 6 respondents (16%) had mild anxiety, 4 respondents (11%) had moderate anxiety, and 3 respondents (8%) had severe anxiety but did not report it. There were some people who were experiencing significant anxiety. The students of SD Negeri 19 Lahat experienced a significantly reduced anxi ety concerning menarche both before and after receiving reproductive health education. DOI : 10.35990/amhs.v2n3.p116-121 REFERENCES Martinez, G. M. (2020). National Health Statistics Reports, Number 146, September 10, 2020. (Original work published 1995). Retrieved from https://www.cdc.gov/nchs/products/index.htm Sinaga, E. S., & Lubis, A. (2021). Factors relating to siswi behavior class VII in facing menarche. Gentle Birth, 4(1). Sudikno, & Sandjaja. (2019). Usia menarche perempuan Indonesia semakin muda: Hasil analisis Riskesdas 2010. Jurnal Kesehatan Reproduksi, 10(2), 163–171. https://doi.org/10.22435/kespro.v10i2.2568.163-171 Sommer, M., Sutherland, C., & Chandra-Mouli, V. (2015). Putting menarche and girls into the global population health agenda. Reproductive Health, 12(1). https://doi.org/10.1186/s12978-015-0009-8 Tanton, C., Nakuya, K., Kansiime, C., et al. (2021). Menstrual characteristics, menstrual anxiety and school attendance among adolescents in Uganda: A longitudinal study. BMC Women's Health, 21(1). https://doi.org/10.1186/s12905-021-01544-6 Starrs, A. M., Ezeh, A. C., Barker, G., et al. (2018). Accelerate progress—Sexual and reproductive health and rights for all: Report of the Guttmacher–Lancet Commission. The Lancet, 391(10140), 2642–2692. https://doi.org/10.1016/S0140-6736(18)30293-9 Prijatni, I. (2013). Kesehatan reproduksi dan keluarga berencana. Badan Pengembangan dan Pemberdayaan Sumber Daya Manusia Kesehatan. Tortora, G. J., & Derrickson, B. (2018). Principles of anatomy and physiology (12th ed.). John Wiley & Sons, Inc. Sherwood, L. (2016). Human physiology: From cells to systems (9th ed.). Cengage Learning. Vismara, M., Girone, N., Cirnigliaro, G., et al. (2020). Peripheral biomarkers in DSM-5 anxiety disorders: An updated overview. Brain Sciences, 10(8), 1–37. https://doi.org/10.3390/brainsci10080564 Hermawatu, Muchtar, M., Wiwi, S., & Syarwini. (2016). Pendidikan kesehatan dalam kesiapan menghadapi menarche di sekolah dasar. Jurnal Penelitian dan Kajian Ilmiah, 10, UMSB. Herwati, Muchtar, M. (2017). Model pendidikan kesehatan terhadap pengetahuan dan sikap dalam kesiapan menghadapi menarche di sekolah dasar. Jurnal Penelitian dan Kajian Ilmiah, 11(75), UMSB. https://doi.org/10.33559/mi.v11i75.453 Mendle, J., Ryan, R. M., & McKone, K. M. (2018). Age at menarche, depression, and antisocial behavior in adulthood. Retrieved from http://www.publications.aap.org/pediatrics/articlepdf/141/1/e20171703/1066419/peds_20171703.pdf Kautsar, F., Gustopo, D., & Achmadi, F. (2017). Uji validitas dan reliabilitas Hamilton Anxiety Rating Scale terhadap kecemasan dan produktivitas pekerja visual inspection PT. Widatra Bhakti. Prosiding SENATEK, 1(A), 588–592. Kementerian Kesehatan Republik Indonesia. (2017). Pedoman dan standar etik penelitian dan pengembangan kesehatan nasional. Ningrum, M. W. P., & Purnomo, W. (2020). Relationship between readiness and anxiety level in elementary school students facing menarche in Pademawu Sub-District, Pamekasan. Jurnal Biometrika dan Kependudukan, 9(2), 95–103. https://doi.org/10.20473/jbk.v9i2.2020.95-103 Burnet Institute, Water Aid Australia, & Aliansi Remaja Independen. (2015). Menstrual hygiene management in Indonesia: Understanding practices, determinants and impacts among adolescent school girls. Retrieved from www.aliansiremajaindependen.org Lutfi, I. (2017). Analisis kesiapan siswi sekolah dasar dalam menghadapi menarche. Jurnal Bioetika dan Kependudukan, 5(2), 135–145. https://doi.org/10.20473/jbk.v5i2.2016.135-145 Emdadul Haque, S., Rahman, M., Itsuko, K., Mutahara, M., & Sakisaka, K. (2014). The effect of a school-based educational intervention on menstrual health: An intervention study among adolescent girls in Bangladesh. BMJ Open, 4, e004607. https://doi.org/10.1136/bmjopen-2013-004607 Intan, O., Hudaya, N., Gantini, D., & Patimah, S. (2019). Pengaruh pendidikan kesehatan reproduksi (Underwear Rules) terhadap pengetahuan anak prasekolah. Edutech: Jurnal Teknologi Pendidikan, 18(3). https://doi.org/10.17509/e.v18i3.18071
Knowledge of Dental Pain Emergency in 45-59 Years Old Community in Cimahi with Clickdent Application R Yuslianti, Euis; Widyasari, Ratih; R Damayanti, Vinsensia
ACTA Medical Health Sciences Vol. 2 No. 3 (2024): ACTA Medical Health Sciences
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Abstract

Dental pain is an unpleasant sensory and emotional experience due to tissue damage, and it is usually felt only in the form of a sensation and described as being different from other sensations. Clickdent is a dental application that can help users manage their dental health by providing information associated with dental health, tracking dental appointments and reminders, and connecting users with dental professionals. This study aimed to characterize the level of knowledge of dental pain emergencies and their management among individuals aged 45-59 using clickdent application. This research employed a descriptive research design with a survey method. The subjects of this study were the residents of Cimahi city, aged 45 to 59 years. The data was gathered through the completion of a questionnaire by the subjects. A total of 100 samples were collected using random sampling, and the obtained data was analyzed using descriptive analyses. The collected data were processed using Microsoft Excel in picture and table. The results showed that the respondent’s level of knowledge about dental pain emergencies had good result with an average of 64.62% answered correctly. It can be concluded that the community has good knowledge about dental pain emergency and the treatment. Clickdent applications can be useful tools to improve dental health management and facilitate access to dental professionals. DOI : 10.35990/amhs.v2n3.p122-129 REFERENCES Couve, E., Lovera, M., Suzuki, K., & Schmachtenberg, O. (2018). Schwann cell phenotype changes in aging human dental pulp. Journal of Dental Research, 1–3. Agusta, R. M. V., A. K. A. I., & Firdausy, M. D. (2014). Hubungan pengetahuan kesehatan gigi dengan kondisi. Mendali Jurnal, 2, 64–68. Franciscatto, G. J., Brennan, D. S., Gomes, M. S., & Rossi-Fedele, G. (2020). Association between pulp and periapical conditions and dental emergency visits involving pain relief: Epidemiological profile and risk indicators in private practice in Australia. International Endodontic Journal, 53, 887–894. Francisco, S. S., Suzuki, C. L. S., Lima, A. P. D. S., Maciel, M. C. R., & Murrer, R. D. (2017). Clinical strategies for managing emergency endodontic pain. RSBO, 13, 210–215. Fejerskov, O., Nyvad, B., & Kidd, E. (2015). Dental caries: The disease and its clinical management (3rd ed., pp. 155–169). Wiley-Blackwell. Woessner, J. (2018). Overview of pain: Classification and concepts. In Weiner’s Pain Management: A Practical Guide for Clinicians (pp. 35–48). Torabinejad, M., Walton, R. E., & Fouad, A. F. (2014). Endodontics: Principles and practice (5th ed., pp. 162–171). Elsevier. Hardadi, M. (2014). Gambaran tindakan pencabutan gigi tetap di Puskesmas Tinumbala Kecamatan Aertembaga Kota Bitung tahun 2013. e-GIGI, 2, 1–6. Siagian, K. V. (2016). Kehilangan sebagian gigi pada rongga mulut. e-CliniC, 4, 1–6. Bachtiar, Z. A. (2016). Perawatan saluran akar pada gigi permanen anak dengan bahan gutta percha. Jurnal PDGI, 65, 60–67. Wintarsih, O., Partosoedarmo, M., & Santoso, P. (2016). Kebocoran apikal pada irigasi dengan EDTA lebih kecil dibandingkan yang tanpa EDTA. Jurnal PDGI, 58, 14–19. Kuhnen, M., et al. (2009). Toothache and associated factors in Brazilian adults: A cross-sectional population-based study. BMC Oral Health, 9(7). https://doi.org/10.1186/1472-6831-9-7 Jaul, E., & Barron, J. (2017). Age-related diseases and clinical and public health implications for the 85 years old and over population. Frontiers in Public Health, 5, 1–7. Kementerian Kesehatan Republik Indonesia. (2019). Laporan hasil Riset Kesehatan Dasar (Riskesdas) Indonesia tahun 2018. Jakarta: Balitbangkes. Clauditiana, T. (2019). Gambaran perilaku kesehatan gigi dan mulut dengan indeks DMF-T pada lansia di UPT pelayanan sosial lanjut usia dinas sosial Binjai. Journal of Chemical Information and Modeling, 53, 3–12. Kristanti, C. M., & Hapsari, D. (2008). Persepsi nyeri gigi dan pola berobat, Susenas 2001. Jurnal Dental Indonesia, 14(1), 53–59. Purra, A. R., Sajad, M., Ahangar, F. A., & Farooq, R. (2018). Patient’s awareness and knowledge of the root canal treatment in Kashmiri population: A survey-based original research. International Journal of Contemporary Medical Research, 5, 2454–7379. Hargreaves, K. M., & Berman, L. H. (2016). Cohen’s Pathways of the Pulp (11th ed., pp. 706–722). Elsevier. Topazian, R. G., Goldberg, M. H., & Hupp, J. R. (2007). Oral and maxillofacial infections (4th ed., pp. 133–150). W.B. Saunders Company. Samaei, H., Weiland, T. J., Dilley, S., & Jelinek, G. A. (2015). Knowledge and confidence of a convenience sample of Australasian emergency doctors in managing dental emergencies: Results of a survey. Emergency Medicine International, 2015.
Profile of risk factors for acoustic trauma in 105 Howitzer Cannon shooter students Kristianti, Asti; Ramdhani, Sony; Amanda Pramesti, Dea
ACTA Medical Health Sciences Vol. 2 No. 3 (2024): ACTA Medical Health Sciences
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Abstract

Acoustic trauma is hearing loss caused by short periods of high-frequency noise. Hearing loss can occur in the military because it uses the main tools of the weaponry system, such as guns, military vehicles, and explosions. This research aims to determine the description of risk factors for acoustic trauma, patterns of hearing protector use, and ear complaints among students of Pusat Pendidikan Artileri Medan (Pusdik Armed) who performed 105 Howitzer Cannon shooting practice. This study used a descriptive method with a cross-sectional design on the students of the Pusdik Armed who practised shooting with 105 Howitzer Cannons. The sampling technique used was total sampling with 103 students. The research instrument is data from questions and blood pressure checks. The results showed a description of the risk factors for acoustic trauma in Pusdik Armed Students who performed Howitzer 105 Cannon shooting practice, which were primarily due to high noise exposure, smoking history, use of PLDs, failure to wear protectors (a small percentage), and use of ototoxic drugs; no one had hypertension and a family history of hearing loss. The patterns of wearing hearing protection during the 105 howitzer cannon firing exercises were gathered from the students who carried out the practice. Additionally, some wore them throughout practice. When it came to ear complaints prior to practice, the majority of students had none before or after cannon shooting practice. Therefore, using ear protective equipment for cannon shooters is necessary. DOI : 10.35990/amhs.v2n3.p130-137 REFERENCES Chadha, S., Kamenov, K., & Cieza, A. (2021). The world report on hearing, 2021. Bulletin of the World Health Organization, 99(4), 242–242A. Orru, H., Luha, A., Pindus, M., Jõgeva, R., Vahisalu, M., Lekk, U., et al. (2020). Hearing loss among military personnel in relation to occupational and leisure noise exposure and usage of personal protective equipment. Noise & Health, 22(107), 90. Retrieved from /pmc/articles/PMC8000139/ Mayasari, D., & Khairunnisa, R. (2017). Pencegahan noise induced hearing loss pada pekerja akibat kebisingan. Jurnal Argomed Unila, 4(2), 354–360. Eryani, Y. M., Wibowo, C. A., & Saftarina, F. (2017). Faktor risiko terjadinya gangguan pendengaran akibat bising. Medula, 7(4), 112–117. Nieman, C. L., & Oh, E. S. (2020). Hearing loss. Annals of Internal Medicine, 173, ITC81–96. Yehudai, N., Fink, N., Shpriz, M., & Marom, T. (2017). Acute acoustic trauma among soldiers during an intense combat. Journal of the American Academy of Audiology, 28(5), 436–443. Chan, Y., & Goddard, J. (2019). J. Lee’s Essential Otolaryngology: Head and Neck Surgery (12th ed., pp. 394–396). McGraw-Hill. Esquivel, C. R., Parker, M., Curtis, K., Merkley, A., Littlefield, P., Conley, G., et al. (2018). Aural blast injury/acoustic trauma and hearing loss. Military Medicine, 183(1), 78–82. (Duplikat referensi no. 2, bisa dihapus jika memang sama) Sasongko, S., & Suteja. (2015). Trauma akustik yang berkaitan dengan prajurit penembak meriam Howitzer 105. In Cimahi: LPPM Unjani (pp. 130–133). Occupational Safety and Health Administration. (n.d.). Occupational noise exposure. Retrieved from https://www.osha.gov/laws-regs/regulations/standardnumber/1910/1910.95 Peraturan Menteri Ketenagakerjaan Republik Indonesia. (2018). Keselamatan dan Kesejahteraan Kerja Lingkungan Kerja. (Duplikat referensi no. 8, bisa dihapus jika memang sama) Toivonen, M., Pääkkönen, R., Niemensivu, R., Aarnisalo, A., & Mäkitie, A. A. (2023). Acute acoustic trauma after exposure to assault rifle noise among conscripts in the Finnish Defence Forces: A population-based survey. International Journal of Environmental Research and Public Health, 20(4). Medina-Garin, D. R., Dia, A., Bedubourg, G., Deparis, X., Berger, F., & Michel, R. (2016). Acute acoustic trauma in the French armed forces during 2007–2014. Noise & Health, 18(85), 297–302. World Health Organization. (2015). Hearing loss due to recreational exposure to loud sounds. Switzerland: WHO. Kristianti, A., & Nurrokhmawati, Y. (2020). Gambaran pola penggunaan personal listening devices (PLDs), dan hasil audiogram pelajar SMPN 3 Cimahi. Medika Kartika: Jurnal Kedokteran dan Kesehatan, 3(2), 103–112. Ningsih, D. L., Marliyawati, D., & Yunika, K. (2018). Pengaruh merokok terhadap gangguan pendengaran pada usia dewasa muda. Jurnal Kedokteran Diponegoro, 7(2), 1380–1390. Li, X., Rong, X., Wang, Z., & Lin, A. (2020). Association between smoking and noise-induced hearing loss: A meta-analysis of observational studies. International Journal of Environmental Research and Public Health, 17(4), 1201. Nasution, D. S., & Nasution, M. E. S. (2020). Hubungan hipertensi dengan gangguan pendengaran di Rumah Sakit Bhayangkara TK II Medan. Jurnal Pandu Husada, 1(4), 221–225. Wang, B., Han, L., Dai, S., Li, X., Cai, W., Yang, D., et al. (2018). Hearing loss characteristics of workers with hypertension exposed to occupational noise: A cross-sectional study of 270,033 participants. BioMed Research International, 2018, 4–5. (Duplikat referensi no. 12, bisa dihapus jika memang sama) (Duplikat referensi no. 4, bisa dihapus jika memang sama) Nurul, S., Meutia, R., Adawiyah, R., Tette, D., & Sofyan, A. (2022). Obat ototoksik (Ototoxic medications). Jurnal Medical Profession (MedPro), 4(1), 49–57. Yulianti, Y., & Mahdiani, S. (2015). Gangguan pendengaran penderita tuberkulosis multidrug resistant. Oto Rhino Laryngologica Indonesiana, 45(2), 83. Benokri, H., Rianto, B., & Sastrowijoto, S. (2020). Gangguan pendengaran sensori pada pasien pasca pengobatan tuberkulosis multidrug resistant selama 6 bulan. Yogyakarta: Universitas Gadjah Mada. Fitriyani, B. B., & Wahyuningsih, S. A. (2016). Hubungan pengetahuan tentang alat pelindung telinga (ear plug) dengan kepatuhan penggunaannya pada pekerja bagian tenun departemen weaving SL PT. Daya Manunggal. Unnes Journal of Public Health, 5(1), 102. Kwak, C., & Han, W. (2021). The effectiveness of hearing protection devices: A systematic review and meta-analysis. International Journal of Environmental Research and Public Health, 18(21), 11693.
A Insights from literature analysis : optimal sunscreen use decreases Melasma incidence in women living in tropical climates Damayanti, Lina; Pradini, Astri; Salsabila, Mitha
ACTA Medical Health Sciences Vol. 2 No. 3 (2024): ACTA Medical Health Sciences
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Melasma is a hyperpigmented patch that is generally found on the face, especiallyon the cheeks, chin, upper lip, and can extend to the neck. The color of hyperpigmentation in melasma varies, generally from light brown to black with an irregular shape. Melasma is often found in countries with tropical climates with skin types III-V. This happens because countries with these climates are exposed to more sunlight. To prevent melasma, it is recommended to use sunscreen to reduce excessive UV exposure to the skin. It is important to use sunscreen optimally in order to reduce the incidence of melasma. The effect of excessive UV exposure to skin, including melasma, can be reduced by applying sunscreen on the regular basis. This literature review used four databases (Google scholar, PUBMED, NCBI and PERDOSKI) and relevant keywords such as "melasma" and "sunscreen" to find the source of articles published in 2010 to 2022. A total of 142 articles in Indonesian and English were found. After selecting based on inclusion and exclusion criteria, 14 relevant articles were obtained and will be discussed in this literature review. The result of this literature review show a significant relationship between optimal use of sunscreen and the incidence of melasma in women from countries with tropical climates, especially in Asia. Melasma is most commonly found in women with Fitzpatrick skin types III-V and more likely to occur between ages 25-60 years. Patients with melasma who used sunscreen optimally, by applying it every 2 hours, showed a decrease in the degree of severity of melasma compared to those who did not repeat the use of sunscreen. The conclusion can be strengthened more straightforward. For example, applying sunscreen every 2h can significantly decrease the incidence of melasma. DOI : 10.35990/amhs.v2n3.p148-156 REFERENCES Rodrigues M, Pandya AG. Hypermelanoses. In: Kang S, Amagai M, Bruckner AL, Enk AH, Margolis DJ, McMichael AJ, et al, editors. Fitzpatrick’s Dermatology. 9th ed. New York: McGraw Hill; 2019. p. 1379-81. Handel AC, Miot LDB, Miot HA. Melasma: a clinical and epidemiological review. An Bras Dermato. 2014;5:772. Sarkar R, Arora P, Garg VK, Sonthalia S, Gokhale N. Melasma Update. Indian Dermatology Online Journal. 2014;5(4):426. Apriliyani PY. Hubungan Antara Pemakaian Tabir Surya Dengan Derajat Keparahan Melasma (Skor MASI) Pada Wanita di Kec. Grogol-Sukoharjo. Surakarta: Fakultas Kedokteran Universitas Muhammadiyah Surakarta; 2017. Shankar KDSR, Somani VK, Kohli M, Sharad J, Ganjoo A, Kandhari S, et al. A cross-sectional, multicentric clinico-epidemiological study of melasma in India. Dermatologic Therapy. 2014;3:71-81. Purba RA. Gambaran Faktor-Faktor Risiko Timbulnya Melasma di Poliklinik Kulit dan Kelamin RSU Royal Prima dan Murni Teguh Memorial Hospital Kota Medan Pada Bulan Desember 2018-Januari 2019. Medan: Fakultas Kedokteran Universitas HKBP Nommesen Medan; 2019. Waskita TW. Hubungan antara riwayat pemakaian tabir surya dengan derajat keparahan melasma. Cimahi: Fakultas Kedokteran Universitas Jenderal Achmad Yani; 2018. Umborowati MA, Rahmadewi. Studi Retrospektif: Diagnosis dan Terapi Pasien Melasma. Berkala Ilmu Kesehatan Kulit & Kelamin. 2014;26:56-61. Krupa S, Devasthanam SR, et al. A cross-sectional, multicentric clinico-epidemiological study of melasma in India. 2014;4.1:71-81. Rattananukrom T, Suchonwanit P, Thadanipon K, Vachiramon V. A Comparative Study of Dermatoscopic Features of Melasma and Hori's Nevus in Asian Patients. J Clin Aesthet Dermatol. 2022;15(3):16-20. Bhattarai S, Pradhan K, Sharma S, Rajouria EA. Clinical patterns and epidemiological characteristics of melasma in a tertiary care hospital of Nepal. Pigment International. 2017;4(1):35. Wu MX, Antony R, Mayrovitz HN. Melasma: A Condition of Asian Skin. Cureus. 2021;13(4). Jha AK, Karki S. Vitiligo and melasma: a psychosocial-cosmetic challenge in context of south Asian countries. J Pigment Disord. 2015. Harumi O, Goh CL. The effect of melasma on the quality of life in a sample of women living in Singapore. The Journal of Clinical and Aesthetic Dermatology. 2016 Jan;9(1):21. Setyawati NK. Insiden dan Profil Melasma di Rumah Sakit Umum Pusat Sanglah Denpasar Periode Januari 2014 Sampai Desember 2014. E-Jurnal Medika Udayana. 2019 Apr 18;8(2). Lahida SP. Hubungan riwayat pemakaian tabir surya dengan kejadian melasma pada wanita usia 25-45 tahun. Jakarta: Trisakti; 2018. Prabawaningrum CD. Hubungan Riwayat Pemakaian Tabir Surya dengan Kejadian Melasma. Surakarta: Fakultas Kedokteran Universitas Negeri Surakarta; 2015. Fatima S, Braunberger T, Mohammad TF, Kohli I, Hamzavi IH. The Role of Sunscreen in Melasma and Postinflammatory Hyperpigmentation. Indian Journal of Dermatology. 2020;65(1):5-10. Sarkar R, Ghunawat S, Narang I, Verma SK, Garg VK, Dua R. Role of broad‐spectrum sunscreen alone in the improvement of melasma area severity index (MASI) and Melasma Quality of Life Index in melasma. Journal of Cosmetic Dermatology. 2019;18(4):1066-1073. Maymone MB, Neamah HH, Wirya SA, Patzelt NM, Zancanaro PQ, Vashi NA. Sun-protective behaviors in patients with cutaneous hyperpigmentation: A cross-sectional study. Journal of the American Academy of Dermatology. 2017;76(5):841-846.
Triple elimination screening for pregnancy: study at Dokter Soekardjo Hospital Desy Aprianti; Susanti Ratunanda
ACTA Medical Health Sciences Vol. 3 No. 1 (2024): Acta Medical and Health Sciences
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Triple Elimination is an initiative that supports the eradication of mother-to-child transmission of three infectious diseases: HIV, syphilis, and hepatitis B. Common tests for this initiative include anti-HIV, RPR-TP, and HBsAg rapid screenings. This descriptive study aimed to determine the results of these screenings in pregnant women at Dokter Soekardjo Hospital. We used a total sampling method to include a total of 182 pregnant women who met the inclusion criteria. The findings revealed that the majority of pregnant women were in early adulthood (26-35 years) and late adulthood (36-45 years), each comprising 32.96%. Most subjects were housewives (84.61%) who had a senior high school education (38.46%) , and were examined during their third trimester (58.80%). The RPR-TP rapid screening showed reactive results in 7 women (3.84%). No reactive results were found for Anti-HIV, while one woman (0.54%) tested reactive for HBsAg. The third trimester detected the most reactive results, with 6 women showing reactivity: 5 (4.675%) for RPR-TP and 1 (0.93%) for HBsAg. Despite the absence of reactive Anti-HIV results, precautions against HIV transmission during pregnancy are crucial due to the risk of placental infection or damage. The study's RPR-TP results highlight the importance of addressing reactive cases, given their potential impact. Additionally, performing HBsAg tests remains critical due to the risk of chronic HBV infection in babies. DOI : 10.35990/amhs.v3n1.p1-11 REFERENCES Mardiyanti I, Rahayu EP, Zuwariah N, Winoto PMP, Karmila HN. The effectiveness of triple elimination examination (HIV, syphilis, hepatitis), roll over test (ROT) and mean arterial pressure (MAP) and self-hypnosis on emergency management of high-risk pregnant women during pandemic. Bali Medical Journal. 2023 Aug 1;12(2):1995–1997. Wu S, Wang J, Guo Q, Lan H, Sun Y, Ren M, et al. Prevalence of human immunodeficiency virus, syphilis, and hepatitis B and C virus infections in pregnant women: a systematic review and meta-analysis. Clinical Microbiology and Infection. 2023 Aug;29(8):1000–1007. Cohn J, Owiredu MN, Taylor MM, Easterbrook P, Lesi O, Francoise B, et al. Eliminating mother-to-child transmission of human immunodeficiency virus, syphilis and hepatitis B in sub-Saharan Africa. Bulletin of the World Health Organization. 2021 Apr 1;99(4):287–295. Bell L, van Gemert C, Allard N, Brink A, Chan PL, Cowie B, et al. Progress towards triple elimination of mother-to-child transmission of HIV, hepatitis B and syphilis in Pacific Island Countries and Territories: a systematic review. Lancet Regional Health – Western Pacific. 2023 Jun;35:100740. Pijoan DI, Jambi M, Herlambang H, Kusdiyah E, Syauqy A, Fitri AD, et al. Peningkatan Pengetahuan Tentang Triple Elimination. Peraturan Menteri Kesehatan Republik Indonesia No. 52 Tahun 2017. Justiz Vaillant AA, Gulick PG. HIV Disease Current Practice. In: StatPearls. 2020. World Health Organization. HIV and AIDS [Internet]. 2023 [cited 2023 Nov 9]. Available from: https://www.who.int/news-room/fact-sheets/detail/hiv-aids Peeling RW, Mabey D, Kamb ML, Chen XS, Radolf JD, Benzaken AS. Syphilis. Nature Reviews Disease Primers. 2017 Oct 12;3(1):17073. World Health Organization. Syphilis [Internet]. 2023 [cited 2023 Nov 8]. Available from: https://www.who.int/news-room/fact-sheets/detail/syphilis Tripathi N, Mousa OY. Hepatitis B. In: StatPearls [Internet]. 2023 [cited 2023 Nov 8]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK555945/ World Health Organization. Hepatitis B [Internet]. 2023 [cited 2023 Nov 8]. Available from: https://www.who.int/news-room/fact-sheets/detail/hepatitis-b Pedoman Penilaian Alat Kesehatan dan PKRT. Kementerian Kesehatan Republik Indonesia; 2018. Ratih WU. Strategi Pemeriksaan Laboratorium Anti-HIV. Jurnal Farmasi Sains dan Komunitas. 2012;11(2):98–103. Liazmi MC. Hubungan Antara Orientasi Seksual dan Penggunaan Napza Suntik Dengan Kejadian Sifilis pada Pasien HIV/AIDS di RSUD Dr. H. Abdul Moeloek Lampung Tahun 2017–2019. [Lampung]: Universitas Lampung; 2020. Satyaputra F, Hendry S, Braddick M, Sivabalan P, Norton R. The laboratory diagnosis of syphilis. Journal of Clinical Microbiology. 2021 Sep 20;59(10). Mehta P, Grant LM, Reddivari AKR. Viral Hepatitis. [Updated 2024 Mar 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554549/ Abaalkhail F, Al-Hamoudi W, Khathlan A, Alghamdi S, Alghamdi M, Alqahtani S, et al. SASLT practice guidelines for the management of Hepatitis B virus – An update. Saudi Journal of Gastroenterology. 2021;27(3):115. Al Amin M. Klasifikasi Kelompok Umur Manusia Berdasarkan Analisis Dimensifraktal Box Counting dari Citra Wajah dengan Deteksi Tepi Canny. MATHunesa: Jurnal Ilmiah Matematika. 2017. Yanti NID, Krisnana I, Lestari P. Hubungan Tingkat Pendidikan dengan Kepatuhan Antenatal Care pada Primigravida Riwayat Pernikahan Dini. Indonesian Midwifery and Health Sciences Journal. 2021 Jun 23;3(2):98–106. Primayanti I, Danianto A, Jumsa R, Geriputri NN, Andari MY. Gambaran Epidemiologi Faktor Risiko Preeklamsia pada Ibu Hamil. Jurnal Kedokteran Unram. 2022;1:785–788. Brunner L, Chagnon Krief P, Probst I, Abderhalden-Zellweger A, Renteria SC, Vonlanthen J, et al. A narrative review on factors associated with job interruption during pregnancy. International Journal of Occupational Medicine and Environmental Health. 2023 Sep 7;36(3):303–323. Peraturan Menteri Kesehatan Republik Indonesia No. 52 Tahun 2017. Gonçalves B, Ferreira C, Alves CT, Henriques M, Azeredo J, Silva S. Vulvovaginal candidiasis: Epidemiology, microbiology and risk factors. Critical Reviews in Microbiology. 2016 Nov 21;42(6):905–927. Widhyasih RM, Geni L, Fauziah PN, Amalia V. Gambaran Hasil Pemeriksaan Skrining RPR-TP Rapid, Anti-HIV dan HBsAg Pada Ibu Hamil di Puskesmas Kecamatan Ciracas. Jurnal Ilmiah Analis Kesehatan. 2020;6(1):82–90. Domingues RMSM, Szwarcwald CL, Souza Junior PRB, Leal M do C. Prevalence of syphilis in pregnancy and prenatal syphilis testing in Brazil: Birth in Brazil study. Revista de Saúde Pública. 2014 Oct;48(5):766–774. Kresno SB. Diagnosis dan Prosedur Laboratorium. Fakultas Kedokteran Universitas Indonesia; 2010. Han GR. Management of chronic hepatitis B in pregnancy. World Journal of Gastroenterology. 2012;18(33):4517. Armini LN, Setiawati EP, Arisanti N, Hilmanto D. Evaluation of Process Indicators and Challenges of the Elimination of Mother-to-Child Transmission of HIV, Syphilis, and Hepatitis B in Bali Province, Indonesia (2019–2022): A Mixed Methods Study. Tropical Medicine and Infectious Disease. 2023 Nov 3;8(11):492.
A qualitative, phenomenological study of scabies patients at Cikatomas Health Center Desy Linasari; Sylvia Mustika Sari; Selly Andriani; Ris kristiana; Henny Juliastuti
ACTA Medical Health Sciences Vol. 3 No. 1 (2024): Acta Medical and Health Sciences
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Abstract

Infestation with the Sarcoptes scabies mite causes scabies, an infectious skin disease that is often found in densely populated areas. This disease is characterized by itching, especially at night, as well as the appearance of rashes and lesions on the skin. Scabies is an endemic public health problem that attacks groups of people with poor personal hygiene. This research aims to understand the experiences of scabies patients regarding their disease journey, including treatment and prevention efforts. The research method used is qualitative with a phenomenological approach. Participants were selected using purposive sampling, and a total of seven participants from Cikatomas Health Center, Tasikmalaya Regency, were included. We collected data through in-depth interviews. From the research results, five themes emerged regarding the experiences of scabies patients in their disease journey: symptoms, risk factors, chain of transmission, treatment efforts, and prevention efforts. In conclusion, during the onset of symptoms, patients reported experiencing intense itching, particularly, in several areas of the body. The most prominent risk factors found in patients were poor personal hygiene and inadequate housing density. The chain of transmission occurred due to contact with other scabies patients, including a history of sharing beds in dormitories and using shared items. Patients sought treatment at health facilities, but did not receive treatment together with friends or other affected family members, thereby allowing the chain of transmission to continue. Prevention efforts have been made by improving personal hygiene. DOI : 10.35990/amhs.v3n1.p12-23 REFERENCES Sungkar S. Skabies: Etiologi, Patogenesis, Pemberantasan dan Pencegahan. Jakarta: Badan Penerbit Fakultas Kedokteran Universitas Indonesia; 2016. Djuanda A, Suriadiredja ASD, Sudharmono A. Ilmu Penyakit Kulit dan Kelamin. Edisi ke-7. Jakarta: Badan Penerbit Fakultas Kedokteran Universitas Indonesia; 2016. Marga P. Pengaruh personal hygiene terhadap kejadian penyakit skabies. J Ilm Kesehatan Sandi Husada. 2020;9(2):773–8. Leung A, Lam J, Leong K. Scabies: A neglected global disease. Curr Pediatr Rev. 2020;16(1):33–42. World Health Organization. Scabies. Geneva: WHO; 2020 [cited 2023 Nov 8]. Available from: https://www.who.int/news-room/fact-sheets/detail/scabies El-Moamly AA. Scabies as part of the WHO roadmap for neglected tropical diseases 2021–2030: What we know and what we need to do for global control. Trop Med Health. 2021;49(1):1–11. Wibianto A, Santoso I. Prevalensi penderita skabies di Puskesmas Ciwidey, Jawa Barat (2015–2020): Studi retrospektif. 2020;1:281–90. Kumarayanti NKD, Hapsari Y, Kusuma DR. Penatalaksanaan skabies dengan pendekatan kedokteran keluarga pada pasien dewasa. J Kedokt. 2020;9(2):220–8. Dinas Kesehatan Jawa Barat. Profil Kesehatan Kabupaten Tasikmalaya 2019. Bandung: Dinkes Jabar; 2019. Available from: https://dinkes.jabarprov.go.id/ Kurniawan M, Sie M, Ling S. Diagnosis dan terapi skabies. Cermin Dunia Kedokteran. 2020;47(2):104–7. Tanto C, Liwang F, Hanifati S. Selekta Kedokteran. Edisi IV Jilid 1. Jakarta: Media Aesculapius; 2016. p. 311–2. Rofifah TN, Budi U. Hubungan sanitasi asrama dan personal hygiene santri dengan kejadian scabies di Pondok Pesantren Al Ikhsan, Banyumas. 2019;38(1):1–23. Suciaty S, Ismail S. Profil penyakit skabies di wilayah kerja Puskesmas Kamonji tahun 2018. Medika Alkhairaat. 2021;3(2):45–50. Naftass Z, Putri TR. Hubungan jenis kelamin, tingkat pendidikan, dan pengetahuan terhadap kejadian skabies pada santri Pondok Pesantren Qotrun Nada, Depok. 2018;10(2):115–9. Muslih R. Hubungan personal hygiene dengan kejadian skabies pada santri Pondok Pesantren Cipasung, Tasikmalaya. Tasikmalaya: Fakultas Ilmu Kesehatan Universitas Siliwangi; 2012. Mutiara H, Syailindra F. Skabies. Med J Lampung Univ (MAJORITY). 2016;5(2):37–42. Handari, Yamin M. Analisis faktor kejadian skabies di Pondok Pesantren An-Nur, Ciseeng, Bogor. J Kedokt dan Kesehatan. 2018;14(2):74–82. Purwanto H, Hastuti RP. Faktor risiko penyakit skabies di masyarakat. J Kesehatan. 2020;11(1):145–50. Mading M, Bule Sopi I. Kajian aspek epidemiologi skabies pada manusia. J Penyakit Bersumber Binatang. 2019;2(2):9–17. Rosumeck S, Nast A, Dressler C. Ivermectin and permethrin for treating scabies (review). Cochrane Library. 2018:60–4. Gunning K, Kiraly B, Pippitt K. Lice and scabies: Treatment update. Am Fam Physician. 2019;99(10):635–42.
Erythrocyte sedimentation rate in new cases of pulmonary tuberculosis patients Marlina Wijayanthy; Susanti Ratunanda
ACTA Medical Health Sciences Vol. 3 No. 1 (2024): Acta Medical and Health Sciences
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This study focuses on the significant health issue of tuberculosis (TB), with Indonesia ranking as the second-highest country worldwide in TB incidence. Diagnostic advancements, including the Rapid Molecular Test (RMT), such as GeneXpert MTB/RIF Ultra, have been pivotal in identifying TB cases. In pulmonary tuberculosis, the Erythrocyte Sedimentation Rate (ESR) reveals an inflammatory process marked by elevated fibrinogen and plasma globulin levels linked to acute-phase reactions. This research, conducted at Waled Regional General Hospital, employs a quantitative descriptive approach with purposive sampling. Data on patient characteristics, new pulmonary TB cases, and ESR results are extracted from medical records, covering the period from January to June 2023. Among the 66 patients who meet the inclusion criteria, the majority (74.2%) belong to the adult age group, with males comprising 68.2%. ESR elevation is observed in 87.9% of cases, averaging 78.3 mm/hour, ranging from 5 to >140 mm/hour. ESR increase is prominent in adult males (83.7%), possibly linked to their higher daily activity and social interactions, enhancing exposure to Mycobacterium tuberculosis. Furthermore, ESR elevation in adult males may be attributed to a higher likelihood of smoking and alcohol consumption, potentially diminishing macrophage, CD4+, CD8+, and T cell activities and consequently intensifying inflammatory processes. This research sheds light on the prevalence and factors contributing to pulmonary tuberculosis, providing valuable insights for targeted interventions and public health strategies. DOI : 10.35990/amhs.v3n1.p24-30 REFERENCES Kementerian Kesehatan Republik Indonesia. Tatalaksana Tuberkulosis: Pedoman Nasional Pelayanan Kedokteran. Jakarta; 2020. Dinas Kesehatan Jawa Barat. Jumlah Kasus Penyakit Tuberkulosis Berdasarkan Kabupaten/Kota di Jawa Barat [Internet]. 2021 [cited 2023 Oct 5]. Available from: https://opendata.jabarprov.go.id/id/dataset/jumlah-kasus-penyakit-tuberkulosis-berdasarkan-kabupatenkota-di-jawa-barat Silvia H, Mellysa R, Citra T. Perbandingan nilai laju endap darah (LED) antara metode Westergren dengan metode mikro ESR pada penderita tuberkulosis paru. Jurnal Medikes. 2018;5(2):182. Sulochana S, Gayathri, Siddartha JR, Fathima J. Clinical significance of erythrocyte sedimentation rate in tuberculosis. Res J Pharm Technol. 2022;15(1):245–9. Kasih KN, Sulastina NA. Analisis laju endap darah pada pasien tuberkulosis paru. J 'Aisyiyah Medika. 2019;4:44–52. Pratiwi CD, Puspitasari E, Nurohmah V. Deskripsi jumlah leukosit dan laju endap darah pada pasien tuberkulosis di RS Paru Dungus Madiun. Borneo J Med Lab Technol. 2019;2(1):92–6. Kementerian Kesehatan Republik Indonesia. 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Overview of rapid molecular test (RMT)–gene xpert mtb/rif ultra results in pulmonary tuberculosis patients based on the history of therapy Balada A Nurinsani; Susanti Ratunanda
ACTA Medical Health Sciences Vol. 3 No. 1 (2024): Acta Medical and Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Tuberculosis (TB) is a health threat that remains a problem both globally and nationally. Indonesia has the world’s second highest number of TB cases. Various examination methods were developed for detecting this disease; one of the most developed is the Rapid Molecular Test (RMT). This study aims to describe the results of a rapid molecular test (GeneXpert) using the Xpert MTB/RIF Ultra tool in pulmonary tuberculosis based on a treatment history consisting of new cases, relapse cases, and drug withdrawal cases. The study subjects were 47 patients with pulmonary tuberculosis at Puskesmas Ciwidey, Bandung Regency Health Office, from February to September 2023. The results showed that characteristics of respondents were male (57.4%), female (42.6%), and mostly were aged between 20 and 44 years (53.1%). These results are in line with previous research. The majority of cases (87.2%) were new cases and the most RMT examination results indicated that MTB detected rifampicin sensitivity (78.7%). In new cases, MTB-detected rifampicin sensitivity at 78.1%, MTB-not detected at 19.5%, and MTB-detected rifampicin resistance at 2.4%. In relapse cases, all respondents (100%) showed MTB detected to be rifampicin-sensitive. In drug withdrawal cases, MTB detected 75% rifampicin sensitivity and 25% rifampicin resistance. The results of this study indicate that one possible factor in the occurrence of germ resistance to antituberculosis drugs is inadequate treatment of TB patients, in this case drug withdrawal cases. DOI : 10.35990/amhs.v3n1.p31-39 REFERENCES Kementerian Kesehatan Republik Indonesia. Tuberkulosis Paru. Pedoman Nasional Pelayanan Kedokteran Tatalaksana Tuberkulosis. 2020; p10–26. World Health Organization. Tuberculosis Incidence. [Internet]. 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