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Journal of Pharmaceutical and Sciences.
Published by Universitas Tjut Nyak Dhien
ISSN : -     EISSN : 26563088     DOI : https://doi.org/10.36490/journal-jps.com
Core Subject : Health, Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 654 Documents
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Optimasi formulasi dan uji fisik sediaan toner dari minyak atsiri lavender (Lavandula angustifolia l.) sebagai anti jerawat Ahmad , Rofi’uddin; Ainiyah , Nur
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.381

Abstract

Lavender is a light lavender-colored flower, has a distinctive and delicate smell, and has anti-inflammatory, antiseptic, antibacterial, antifungal, antidepressant, and can reduce acne. The purpose of this study is to make a toner preparation formulation from lavender essential oil as an anti-acne with variations in glycerin and propylene glycol concentrations so that an optimal formula is produced. The method used in this study is Simplex Lattice Design. The physical tests of toner preparations carried out include organoleptic, homogeneity, pH, dry time, and displaced volume. The response from the physical evaluation was processed to obtain the optimal formula. The results of the physical test of the optimum preparation were then analyzed using the One Sample T-Test with the SPSS application. Formula optimization yielded a concentration of 10% glycerin and 7% propylenglycol. The optimal preparation of lavender toner is clear white with a distinctive lavender smell and liquid form, a homogeneous preparation, a pH value of 6.17, a drying time of 1.12 minutes, and a transferred volume of 98 ml so that the optimal preparation of lavender toner meets the requirements of a good toner. The results of the One Sample T-Test analysis showed no difference.
Gambaran proses perencanaan dan pengadaan kebutuhan farmasi di apotek farmarin dalam perspektif Islam Nastiti, Nindita Sari; Amanda, Salsabila; Yanualisarani, Cahyani
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.402

Abstract

Medicines are a very important element in health care efforts, therefore the availability of medicines must always be guaranteed. Unsecured availability of medicines, or shortages of medicines in pharmaceutical facilities such as pharmacies, can result in lowering the level of consumer confidence. In an Islamic perspective, the need for medicine is included in maqashid al-dharuriyyat (primary needs) because it is related to preserving life or maintaining the soul (hifdz al-nafs). This research uses a descriptive method with a qualitative approach. Based on the research that has been carried out, it can be concluded that the planning and procurement process at the Farmarin pharmacy is in accordance with pharmaceutical service standards and is in accordance with the Islamic perspective, namely procurement at the Farmarin pharmacy using consumption methods and epidemiological methods and taking into account the halalness of medicines.
Karakteristik dan aktivitas antibakteri minyak atsiri daun cengkeh dari daerah cluwak terhadap bakteri Staphylococcus aureus ATCC 25923 Rahmawati , Laily Mega; Januarti , Ika Buana; Assidiqi , Elok Rosita; Rosyida , Raissa
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.484

Abstract

Essential oil is a potential wealth of Indonesia's natural resources as a raw material for medicines and cosmetics. Cengkeh leaf essential oil contains the main component of eugenol as an antibacterial. The purpose of this study was to determine the characteristics and antibacterial activity of cengkeh leaf essential oil from Cluwak region against Staphylococcus aureus ATCC 25923 bacteria. Cengkeh leaf essential oil was distilled by water vapor distillation method. Characterization of essential oil was performed on refractive index, optical rotation, and compound component analysis by GC-MS. Antibacterial activity was tested by the well diffusion method to obtain the diameter of inhibition at each concentration. Cengkeh leaf essential oil has a refractive index of 1.5303 and an optical rotation of 0.55. Analysis of the main components of the essential oil contains 7 main compound components with the highest compound m-eugenol. The diameter values of inhibition in antibacterial activity with concentrations of 10%, 20%, and 40% were 9.44 mm, 11.48 mm, and 12.37 mm, respectively. The characteristics of the essential oil are in accordance with the standard and the antibacterial activity is categorized as weak inhibition.
Artikel review : Kecantikan alami dengan kopi: panduan lengkap masker gel wajah berbasis kopi buatan Indonesia Jannah, Roudotul; Syahrin, Esti; Sudarjat, Hadi
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.521

Abstract

The increasing ‘back to nature’ trend in Indonesia has brought about a variety of beauty products infused with natural ingredients. Coffee is an Indonesian natural resource that has a variety of active compounds in it that are useful as antioxidants. The antioxidant compounds in coffee can be formulated into peel off- masks that help maintain healthy facial skin. The purpose of this review article is to determine the development and mapping of research topics on coffee masks using bibliometric analysis and to review and provide a summary of several scientific articles related to the formulation, safety, and effectiveness of arabica and robusta coffee peel-off gel mask preparations as antioxidants. The data set used was sourced from the publication of national and international scientific articles indexed by Google Scholar in the range of 2019-2024. The stages carried out include: 1) determining the topic, 2) collecting data using a reference manager in the form of Publish or Perish software, 3) processing the data obtained with Microsoft Excel software 4) conducting bibliometric analysis and visualizing it using the help of VOSviewer software and, 5) reviewing articles. The results of the bibliometric analysis showed that publications on coffee masks experienced fluctuating development.  Based on the visualization of bibliometric mapping, research on coffee masks is divided into 4 clusters consisting of 15 interrelated items. Based on the results of the review article, there are 6 original research related to the formulation and evaluation of coffee peel-off gel masks that are discussed in depth and it can be concluded that peel-off gel masks from coffee, both robusta and arabica coffee, have been proven safe and effective for the skin.
Meningkatkan Kualitas Pelayanan Farmasi: Evaluasi Sistem Penyimpanan Obat Berdasarkan Standar Kefarmasian dan Prinsip Syariat Islam di Puskesmas Tlogosari Wetan Semarang Kartika, Erza Ridha; Lola , Shofi
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.536

Abstract

Pharmaceutical Services are direct pharmaceutical service activities to patients related to the provision of medicines with the aim of obtaining clear results in order to improve the quality of patients. Pharmaceutical service standards are a benchmark used as a guideline for pharmacists in implementing pharmaceutical services. Tlogosari Wetan Health Center, Semarang City is a parent health center that has 3 auxiliary health centers, including: Kekancan Mukti Health Center, Pedurungan Kidul Health Center, and Plamongansari Health Center. This study aims to evaluate the storage of pharmaceutical preparations Based on Pharmaceutical Service Standards at Tlogosari Wetan Health Center and Based on Islamic Sharia Principles. This study is descriptive using data collection techniques, namely interviews, observations, and documentation.
Optimasi Formulasi Cleansing Balm Minyak Biji Tomat (Solanum lycopersicum) dengan Simplex Lattice Design: Karakteristik Fisik dan Efek Anti-Aging Suryani , Arman; Cahyaningsih , Tri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.561

Abstract

This study aims to optimize the formulation of tomato (Solanum lycopersicum) seed oil-based cleansing balm with a Simplex Lattice Design (SLD) approach and evaluate its physical characteristics for facial cleansing and potential anti-aging effects. The research method used was formulation with the main component variables of shea butter, beeswax, caprylic/capric triglycerides, and tween 20, which were analyzed using SLD to obtain the optimal combination. The optimization results showed that the formulation with concentrations of shea butter (4.97996 %), beeswax (1.88189 %), caprylic/capric triglycerides (42.1382 %), and tween 20 (1 %) provided a good quality preparation with a semi-solid texture, typical beeswax aroma, and bone white color. The physical characteristics of the product, such as melting temperature stabilized at 38.67 °C ± 0.58, spreadability of 5.43 cm ± 0.12, and pH of 5.03 ± 0.06, showed that the product was safe and ideal for the skin. The product stability test for seven days of storage showed no significant changes in melting temperature and spreadability, although there was a slight increase in pH. In addition, the product showed good antioxidant activity with 46.51% free radical inhibition and an IC50 value of 21.46 ppm, indicating potential protection against oxidative stress-induced skin damage. In conclusion, the tomato seed oil cleansing balm optimized through SLD has stable, safe, and effective performance as a skincare product with anti-aging benefits.
Gambaran Kepatuhan Minum Obat Pada Pasien Hipertensi di Salah Satu Puskesmas Semarang Barat Jawa Tengah Dewi, Rissa Maharani; Widiya , Hartika; Farizi , Gilang Rizki Al
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.563

Abstract

Introduction: Hypertension is a medical condition characterised by blood pressure that is higher than usual and persistent. Based on previous studies, it was found that the low level of compliance in taking medication was related to a decrease in the quality of life for hypertensive patients. This study aimed to determine the compliance of hypertensive patients with taking medicines at one of the West Semarang Community Health Centres, Central Java. Methods: Analytic descriptive research. This type of research is observational with cross-sectional techniques, with respondents being hypertensive patients at one of the Puskesmas in West Semarang, Central Java, in 2023. Data analysis was conducted by looking at whether or not drug compliance affected patient characteristics using the chi-square Morisky Medication Adherence Scale 8 (MMAS-8) test. Results: female gender is higher than male, age 36 years to 45 years and 56 years to 65 years have high adherence, diploma and undergraduate education have high adherence values, occupation of housewives and civil servants / TNI / POLRI have high adherence to taking medication and long suffering above 2 years of moderate drug compliance, hypertension therapy with 2 to 3 drugs moderate adherence rather than one drug, other disease characteristics are equally high in adherence.Conclusion: Adherence to the use of antihypertensive medications in one Puskesmas in West Semarang, Central Java, was in the high and medium categories. Men have a moderate adherence category, and women have a high adherence category.
Potensi hepatoprotektif ekstrak daun Euphorbia heterophylla L. dalam menurunkan kadar bilirubin pada tikus Wistar yang diinduksi INH dan rifampisin Kurniasih, Khamdiyah Indah; Fauziah, Fauziah; Ratna, Uki Septi
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.592

Abstract

Hepatitis is a liver damage disorder characterized by inflammation caused by various factors, one of which is medication use. Liver damage due to medication, or drug-induced liver injury (DILI), has a relatively high prevalence. Isoniazid (INH) + Rifampicin is a combination of drugs that poses a risk of DILI by causing liver damage. One parameter for assessing liver damage is through the measurement of total serum bilirubin levels. Katemas herb (Euphorbia heterophylla L) is a plant known to contain flavonoids, tannins, and saponins, with strong antioxidant properties. The high incidence of liver damage due to drug-induced liver injury (DILI) necessitates the exploration of alternative therapies to manage liver disorders. Katemas is a wild grass that grows abundantly but remains underutilized.The objective of this study is to evaluate the hepatoprotective activity of katemas herb leaves. The method used in this research involves maceration to obtain extracts, with ethanol 96% as the solvent. Testing was conducted on five groups of rats, with total serum bilirubin levels measured across all groups. All groups were induced using INH and RMP. The results showed that Groups III and IV, which were the dose variation groups, exhibited hepatoprotective activity. Group V, which received the highest dose of 200 mg/kg BW, demonstrated the greatest reduction in total bilirubin levels, with the largest mean decrease (-0.226) and a small standard deviation (±0.043).
Dampak Kualitas Pelayanan Berbasis Nilai Syariah di Apotek Karya Sehat Purwokerto Terhadap Kepuasan Konsumen Rizki, Inesya Febrianing; Hardiyanti , Annisa Mufidah; Rismayanti , Rismayanti
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.618

Abstract

Sharia-based services can improve consumer satisfaction. The four main principles of Islamic teachings on service are Rabbaniyyah, service, Waqi'iyyah, and Insaniyyah. The high and low quality of service can be determined by consumer behavior, namely Rabbaniyyah, Akhlaqiyyah, Waqi'iyyah, and Insaniyyah. The high and low quality of service can be determined by consumer behavior. The purpose is to determine how the quality of sharia-based services influences customer behavior. This research method is a cross-sectional design that is included in descriptive observation. The results showed that sharia-compliant pharmaceutical services positively impact customer satisfaction, as the significant value exceeds a t-value of 0.05. In conclusion, the quality of sharia-based services affects customer satisfaction.
Uji efektivitas antidiabetes nanoherbal dan ekstrak etanol daun toppaspara (Mikania micrantha Kunth) Pada Tikus Putih Jantan (Rattus Norvegicus) yang diinduksi streptozotosin Indah Setyarini, Putri Ayu; Gunawan , Muhammad; Safriana, Safriana; Fatimah , Cut
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.697

Abstract

Diabetes mellitus is a metabolic disease characterised by hyperglycemia caused by insufficient insulin production, insulin resistance, or both. The use of natural ingredients as a treatment option for diabetes mellitus can be developed as an alternative treatment, one of which is the toppaspara plant (Mikania micrantha Kunth.). The very small particle size in nano form is used to increase antidiabetic activity. Toppaspara leaves (Mikania micrantha Kunth.) have been empirically used as an antidiabetic, but this has not been scientifically proven. This research aims to determine the effectiveness of nanoherbal and ethanol extract of toppaspara leaves. This research was carried out experimentally, including the manufacture of simplicia, characterisation of simplicia, characterisation of nanoherbals and testing of antidiabetic effectiveness. Male white mice were induced with 2.5% streptozotocin intraperitoneally. Administration of 0.5% CMC suspension, nanoherbal and ethanol extract of toppaspara leaves at 50 mg/kgBB, 100 mg/kgBB, 200 mg/kgBB, metformin 45 mg/kgBB. The number of decreases in blood glucose levels is calculated; from the number of decreases in blood glucose levels, the percentage decrease in blood glucose levels is calculated. This analysis test uses One-way ANOVA followed by the Tukey test. The results of phytochemical screening of fresh leaves, simplicia ethanol extract and nano herbal toppaspara leaves contain secondary metabolite compounds such as alkaloids, tannins, flavonoids, saponins, steroids and glycosides. The results of the One Way ANOVA test and the Tukey test showed that nanoherbal 100 mg/kgBW and ethanol extract of toppaspara leaves 200 mg/kgBW were the best as antidiabetics and were not significantly different from metformin 45 mg/kgBW as a comparison.

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