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Fitria Megawati
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Usadha
Published by Universitas Mahasaraswati
ISSN : -     EISSN : 29632161     DOI : https://doi.org/10.36733/usadha.v2i2
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Usadha: Jurnal Integrasi Obat Tradisional, bertujuan untuk mendorong integrasi Obat Tradisional ke dalam sistem pelayanan kesehatan modern dalam bentuk pertukaran informasi ilmiah baik di kalangan peneliti, praktisi obat tradisional dan tenaga medis, pemegang kebijakan, industri dan stakeholder lainnya, dalam upaya pengembangan obat tradisional untuk masyarakat. Usadha menerima berbagai macam hasil penelitian dari berbagai bidang ilmu baik dalam bentuk artikel original, artikel review, maupun komunikasi singkat yang berkaitan dengan upaya untuk mendorong integrasi dan pengembangan obat tradisional mulai dari hulu hingga ke hilir, yang dapat meliputi namun tidak terbatas pada: 1) eksplorasi dan identifikasi bahan obat tradisional; 2) identifikasi zat aktif dari bahan alam; 3) pembuktian ilmiah khasiat dan keamanan obat tradisional baik preklinis maupun klinis; 4) pengembangan teknologi ekstraksi dan isolasi senyawa bahan alam; 5) teknologi produksi dan penghantaran obat berbasis bahan alam serta kosmetika herbal; 6) pengembangan produk nutrasetika dari bahan herbal; 7) sistem pelayanan obat tradisional di klinik dan komunitas; 8) kebijakan di bidang obat tradisional, konservasi dan budidaya tanaman obat tradisional; dan lainnya yang dalam lingkup obat tradisional. Usadha diterbitkan oleh Fakultas Farmasi Universitas Mahasaraswati Denpasar, dengan jumlah terbit 3 kali dalam setahun pada bulan April, Agustus, dan Desember.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 66 Documents
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Kajian Etnofarmasi Kelompok Masyarakat Banjar Kepisah Sumerta Kelod Denpasar Dewi, Ni Luh Kade Arman Anita; Adi Lestari, Ni Putu Wisnu; Suradnyana, I Gede
Usadha Vol 2 No 2 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i2.7390

Abstract

Ethnopharmacy is a part of pharmaceutical science that includes understanding medicinal plants used and studying how certain ethnic or community communities use drugs. Studies on ethnopharmaceuticals have never been carried out on the community in the Sumerta Kelod area, especially the Banjar Keseparat community. Where there are still many Banjar Keseparat people who use plants as medicine. This research is a descriptive research. Data collection was done by interview method. The sampling technique in this study used a non-probability sampling method. The results showed that ethnopharmaceutical research that had been carried out in Banjar Kejuangan, Sumerta Kelod obtained in general 12 types of plants that were located in Banjar Kejuangan, Sumerta Kelod. Where the plant parts used were 67% leaves, 17% rhizomes, 8% stems, and 8% flowers. The method of processing plants with the highest frequency was by boiling, which was 92%. The most frequently used method of using ethnopharmaceutical plants is by drinking, which is equal to 83%, and the most frequently used indication for medicinal plants is to treat joint problems, such as muscle pain and gout (28%).
Uji Aktivitas Afrodisiaka Sediaan Tablet Effervescent Ekstrak Kombinasi Buah Pare (Momordica Charantia L.) Dan Bawang Putih (Allium Sativum L.) Pada Mencit Putih Jantan (Mus Musculus L.) Listina, Osie; Nurhidayati, Lailiana Garna; Fia, Nela Selfi Nur Okta
Usadha Vol 2 No 2 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i2.7467

Abstract

Aphrodisiacs are substances derived from food or medicine that can enhance sexual desire. This study aimed to evaluate the aphrodisiac activity of effervescent tablet formulations containing extracts of bitter melon (Momordica charantia L.) and garlic (Allium sativum L.), both individually and in combination, in male white mice (Mus musculus L.). The ICC method (Introduction, Climbing, Coitus) was applied to 25 male Wistar mice divided into five groups. Group I served as the negative control and received distilled water orally. Group II was administered an effervescent tablet solution containing bitter melon extract at a single dose of 980 mg/kg BW. Group III received an effervescent tablet solution containing garlic extract at a single dose of 150 mg/kg BW. Group IV was given a combination effervescent tablet solution at a ½:½ ratio (bitter melon extract 490 mg/kg BW and garlic extract 75 mg/kg BW). Group V received a combination effervescent tablet solution at a 1:1 ratio (bitter melon extract 980 mg/kg BW and garlic extract 150 mg/kg BW). Observations were conducted for 2 hours, recording the frequency of ICC behaviors. Data were analyzed using SPSS with ANOVA followed by Post Hoc tests. The results showed that all treatment groups exhibited significant differences in aphrodisiac activity, with the highest frequency observed in the 1:1 combination of bitter melon extract (980 mg/kg BW) and garlic extract (150 mg/kg BW) compared to other effervescent tablet formulations.
Formulasi dan Uji Fisik Ekstrak Biji Alpukat (Persea aericana Mill) dengan Cangkang Telur Sebagai Body Scrub Fahamsya, Arifina; Listina, Osie
Usadha Vol 2 No 2 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i2.7478

Abstract

Avocado seeds contain secondary metabolites such as alkaloids, flavonoids, saponins, tannins, and vitamin E, which are beneficial for skin care. A body scrub is a skin care preparation in the form of a liquid emulsion consisting of an oil phase and an aqueous phase, combined with abrasive particles that function to moisturize, cleanse skin pores, remove dead skin cells, and serve as a carrier for active compounds into the skin. This study aims to formulate a body scrub containing ethanol extract of avocado seeds that meets physical quality requirements and to determine its irritation potential. The ethanol extract of avocado seeds was obtained through maceration and remaceration methods. Four formulations were prepared: F0 (base), F1 (1%), F2 (5%), and F3 (10%). Physical evaluations included organoleptic testing, pH measurement, homogeneity, spreadability, adhesiveness, viscosity, and irritation testing. The results showed that the formulated body scrub met the physical quality requirements, with irritation scores ranging from 0.3 to 1.3, indicating very mild to mild irritation.
Pengetahuan dan Sikap Pasien terhadap Swamedikasi Pemilihan Obat Tradisional dan Konvensional di Apotek Dharma Medika Badung Susianti, Luh; Megawati, Fitria; Agus Adrianta, Ketut
Usadha Vol 3 No 1 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i1.7220

Abstract

  According to the World Health Organization (WHO), self-medication is choosing and using modern medicine, herbal medicine, or traditional medicine to reduce or overcome a disease or disease symptoms. The implementation of self-medication must be distinct from the use of traditional medicine and conventional medicine, where preferences for drug selection are greatly influenced by knowledge and attitude factors. This research aimed to determine the level of knowledge and attitudes toward choosing traditional and conventional medicines and self-medication in the Dharma Medika Badung Pharmacy patients. The research design used was observational descriptive, and the sampling technique was carried out using the accidental sampling method. A total of 68 respondents met the inclusion and exclusion criteria. The instrument in this research was a closed questionnaire with 14 questions, where the questionnaire's validity and reliability were first tested. The results showed that the level of knowledge of the respondents with "Good" criteria is 63%, "Fair" criteria is 28%, "Not Good" is 6%, and "Not Good" is 3%. Most patients at the Dharma Medika Badung Pharmacy have a good level of knowledge regarding the choice of traditional and conventional medicines, with respondents' attitudes tending to be positive towards conventional medicines compared to traditional medicines in terms of self-medication
Uji Aktivitas Antibakteri Rebusan dan Infusa Daun Jeruju (Achantus illicifolious) terhadap Bakteri Methicilin Resistant Staphylococcus aureus (MRSA) Maria Dewi, Ni Putu; Cahyaningsih, Erna; Arman Anita Dewi, Ni Luh Kade; Surya Rahadi, I Wayan; Sandhi Kusuma Yuda, Putu Era; Santoso, Puguh
Usadha Vol 3 No 1 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i1.7222

Abstract

Infectious diseases are still a health problem throughout the world, including in Indonesia. One cause of infection that needs to be watched out for is resistance to Methicillin-Resistant Staphylococcus aureus (MRSA) bacteria. Continuous use of antibiotics can cause problems with microbial resistance. Indonesia has various plant species that can actually provide benefits but have not been specifically cultivated. Jeruju leaves (Achanthus ilicifolius) from mangrove plants contain bioactive compounds that have the potential to be antibacterial. The aim of this research is to determine the antibacterial activity of Jeruju leaf decoction and infusion against MRSA bacteria. Antibacterial activity testing uses MRSA bacteria. The results of the phytochemical screening of Jeruju leaf infusion contained secondary metabolite compounds in the form of flavonoids, tannins, saponins and quinones. Meanwhile, the results of the phytochemical screening of Jeruju leaf decoction contained secondary metabolites in the form of tannins, saponins and quinones. Based on the results of research conducted on infusions and decoctions of Jeruju leaves at concentrations of 30%, 60% and 90%, they did not have inhibitory power on the antibacterial activity of MRSA, as seen from the inhibition zone. Zero inhibition zone for MRSA bacteria. It can be concluded that the infusion and decoction of Jeruju (Achantus illicifolious) leaves do not have antibacterial activity against MRSA.
Analisis Kadar Lemak dan Kadar Air pada Simplisia Biji Kakao (Theobrama Cacao L.) Desa Gumbrih, Kecamatan Pakutatan, Kabupaten Jembrana Sugiantari, Widiya; Chandra Wibawa, Agung Ari; Pramitha, Dewa Ayu Ika
Usadha Vol 2 No 3 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i3.7251

Abstract

Cocoa fruit seeds derived from the cocoa plant (Theobroma cacao L.) is one of the raw materials that are very widely used in the community either as food, beverages, or additives in the pharmaceutical field. The content of primary metabolite compounds in cocoa beans such as fat, carbohydrates, water and protein is a very important standard in determining the quality of cocoa beans.  Fat and water content is the first parameter in determining the quality and quality of cocoa beans. Gumbrih Village, Jembrane sub-district, Bali is currently one of the largest suppliers of cocoa beans in Bali for export. However, there is no data related to fat and water content.  This study was conducted with the aim of knowing the quality standards of fat content and water content in cocoa beans from Gumbrih Village, Pakutatan District, Jembrana Regency, as well as to determine the relationship between the effect of water content on fat content. The research design uses experimental research in the laboratory with the aim of analysis. Method used in this study is the analysis of fat content using the soxlhetation method with N-hexane solvent and in the analysis of water content using the gravimetric method. The results showed that the cocoa bean samples in Gumbrih Village, Pakutatan District, Jembrana Regency did not meet the quality standards with an average fat content of (55.95±1.64)% and an average water content that did not meet the quality requirements of (9.5±0.47)%.  
Uji Aktivitas Antibakteri Ekstrak Etanol Bulung Sangu (Gracilaria Sp.) Terhadap Bakteri Gram Negatif Pseudomonas aeruginosa Putri, Leoni; Vernandes Sasadara, Maria Malida; Cahyaningsih, Erna; Santoso, Puguh
Usadha Vol 2 No 3 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i3.7262

Abstract

Pseudomonas aeruginosa is a gram-negative bacterium that is pathogenic to humans, especially in causing nosocomial infections. This bacterium has resistance to several classes of antibiotics, one of which is carbapenem and cephalosporin class antibiotics. The development of new antibiotics is an alternative in solving this case. Seaweed is one of the marine biota that has various benefits to be developed due to its primary and secondary metabolite compounds. Secondary metabolites in seaweed are used as a source of bioactive metabolites which have broad antiviral, antifungal and antibacterial activities. Bulung sangu (Gracilaria sp.) is one of the seaweeds that has biological activity as an antibacterial. This study aims to determine the antibacterial effectiveness of 70% ethanol extract of bulung sangu (Gracilaria sp.) on the growth of Pseudomonas aeruginosa bacteria. Sangu bamboo shoots were obtained from the southern Denpasar area (Bali). Bulung sangu viscous extract was extracted using 70% ethanol by ultrasonic method for 5 minutes at 40oC. Phytochemical screening of the extract was carried out to determine the content of secondary metabolite compounds it had. Antibacterial activity testing was carried out using the well diffusion method using 3 extract concentrations namely 4%, 8% and 12%. The positive and negative controls used were chloramphenicol antibiotics and sterile aquadest. Inhibition zones were observed and expressed as mean ± standard deviation (mm). The results were statistically analyzed using Kruskal-Wallis with a 95% confidence level. The inhibition zones generated from the positive control, concentrations of 4%, 8% and 12% could inhibit Pseudomonas aeruginosa bacteria with the following average diameters of the inhibition zones of 25.67mm, 2.00mm, 2.67mm and 2.67mm in the weak inhibition zone category.
Tingkat Pengetahuan Masyarakat tentang Obat Tradisional di Banjar Pejeng Aji Tegalalang Gianyar Wiradana, Dewa Gde Adi; Dewi Agustini, Ni Putu; Tangkas Suwantara, I Putu; Megawati, Fitria
Usadha Vol 2 No 3 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i3.7287

Abstract

Traditional medicine is more widely used by people in rural areas because it is easy to obtain and easy to obtain at relatively cheap prices. Traditional medicine has the ability to cure various kinds of diseases with ingredients that have been trusted for generations. The purpose of this study was to find out how far the level of public knowledge about traditional medicine in Banjar Pejeng Aji, Tegalalang, Gianyar. This research is a type of observational research that is descriptive in nature where data collection techniques are carried out using questionnaires. This research was conducted in Banjar Pejeng Aji, Tegalalang, Gianyar with a population of 254 heads of families and a sample of 80 respondents with an age range of 17-65 years was obtained. The data obtained from the research is then processed by calculating the percentage value of the respondents' answers. The results of the analysis of the questionnaire data obtained from 80 respondents showed that the level of public knowledge in Banjar Pejeng Aji, Tegalalang, Gianyar was in the Good category, where out of 80 respondents who were the research sample 75 respondents (93.75%) respondents had good knowledge, 5 respondents (6.25%) had sufficient knowledge and 0 (0%) respondents had less knowledge
Pengujian Fitokimia dan Penentuan Kadar Senyawa Saponin Pada Ekstrak Etanol Bunga Telang (Clitoria ternatea L.) Nugraha, Nyoman Dhamapada; Sukma Sanjiwani, Ni Made; Wahyu Udayani , Ni Nyoman
Usadha Vol 3 No 1 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i1.7345

Abstract

Butterfly pea flower (Clitoria Ternatea L.) has long been used as a traditional medicine to cure various diseases so that it is used as a family medicinal plant (TOGA). Telang flower (Clitoria Ternatea L.) has properties as an antimicrobial, anthelmintic, or antiparasitic and insecticidal agent, fever medicine and pain reliever, anticancer, antioxidant, lowering blood sugar levels, anti-cholesterol, hypo-allergenic, immunomodulator and can be used in the treatment of wounds and can treat red eyes, tired eyes, skin diseases, and anti-toxins (Purba, 2020). This study aims to determine the presence or absence of saponins in the ethanol extract of butterfly pea and to determine the levels of saponins contained in the ethanol extract of butterfly pea (Clitoria Ternatea L.). A qualitative test was carried out by putting 0.5 gram of butterfly pea flower simplicia powder (Clitoria Ternatea L.) into a test tube, then adding 10 ml of hot water, shaking vigorously for 10 seconds and adding 2N HCl, then a quantitative test was carried out using the gravimetric method. Based on the research results that have been carried out positive butterfly pea flower extract (Clitoria Ternatea L.) contains saponin compounds with a saponin content of 1.54% using the gravimetric method. Keywords: Butterfly Pea Flower (Clitoria Ternatea L.), Saponins, Gravimetric Method.
Kajian Etnofarmasi Kelompok Masyarakat Banjar Saraseda Tampaksiring Gianyar Bali Puspita Wati, Ni Putu; Anita Dewi, Ni Luh Kade Arman; Suradnyana, I Gede Made; Kusuma Yuda, I Putu Era Sandhi; Cahyaningsih, Erna; Megawati, Fitria
Usadha Vol 2 No 3 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i3.7376

Abstract

  The use of ethnopharmaceutical practices remains widespread in Bali, as this knowledge has been passed down through generations. Although the Balinese people still strongly uphold their traditional healing systems and have long utilized plants as medicinal ingredients, there is still limited research documenting the diversity of plant species recorded in the Usadha manuscripts along with their therapeutic uses. This study aimed to inventory medicinal plants that are still used by the community in Banjar Saraseda, Tampaksiring, Gianyar, Bali. The study employed a descriptive design, with data collected through interviews to obtain information from respondents regarding local plant names, therapeutic uses/indications, parts of the plant utilized, and methods of preparation and application. The data were analyzed descriptively and presented in tables. Based on the ethnopharmacological survey conducted in Banjar Saraseda, Tampaksiring, Gianyar, Bali, a total of 20 medicinal plant species were recorded. The most frequently used plant parts were leaves (75%), followed by rhizomes (15%) and fruits (10%). The primary methods of preparation included boiling (65%), pounding (15%), grating, crushing, brewing, and direct use (each 5%). Based on therapeutic indications, the plants were mainly used to treat fever (20%), muscle pain and gout (20%), hypertension (20%), skin itching (10%), diabetes (10%), and to manage wounds, diarrhoea, haemorrhoids, and gastritis (each 5%). This study demonstrates that the Banjar Saraseda community in Tampaksiring, Gianyar, Bali continues to preserve traditional knowledge in the use of medicinal plants that has been inherited through generations.

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