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INDONESIA
Indonesian Journal of Health Research and Development
Published by CV Media Inti Teknologi
ISSN : -     EISSN : 29879671     DOI : https://doi.org/10.58723/ijhrd.v1i2.99
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Indonesian Journal of Health Research and Development with E-ISSN: 2987-9671 is a journal managed by CV Media Inti Teknologi. Publish articles on Research activities in the fields of : 1. Nursing 2. Medicine 3. Pharmacy 4. Health Innovation 5. Kebidanan (Bostetrics) 6. Healthy Education 7. Nutrition and Food 8. Health Administration 9. health promotion 10. Physiotherapy 11. Radiology 12. Stunting 13. Health Technology. 14. Sanitation.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 52 Documents
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Formulation and Physical Stability Evaluation of Sacha Inchi (Plukenetia volubilis L.) Oil-Based Body Lotion as Skin Moisturizer Neni Sri Gunarti; Putri Immelia, Richa; Farhamzah; Eko Sriwahyuningsih
Indonesian Journal of Health Research and Development Vol. 3 No. 3 (2025): Indonesian Journal of Health Research and Development
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/ijhrd.v3i3.462

Abstract

Background: Sacha Inchi oil (Plukenetia volubilis L.) is rich in essential fatty acids and antioxidants, making it a promising active ingredient in body lotion formulations for skin moisturization and protection.Aims and Scope: This study aimed to evaluate the effect of varying concentrations of Sacha Inchi oil on the physical stability, moisturizing effectiveness, and user acceptability of body lotion formulations.Methods: Three body lotion formulas were prepared with Sacha Inchi oil at concentrations of 5% (F1), 6% (F2), and 7% (F3). Evaluations included organoleptic observations, pH measurement, viscosity, spreadability, moisturizing effectiveness using a skin analyzer, irritation tests, and hedonic tests involving 20 panelists.Result: Formula F3 demonstrated the best moisturizing effectiveness, increasing skin moisture by 20.45%, with a pH of 6.45, viscosity of 6,150 cP, and spreadability of 5.4 cm. Although F3 had the highest moisturizing effect, F2 was the most preferred by panelists, with 83.3% indicating strong preference for texture and 72.2% for spreadability. All formulas showed no signs of irritation.Conclusion: The body lotion containing 7% Sacha Inchi oil (F3) was the most effective in enhancing skin moisture, while the 6% formulation (F2) was the most favorable in terms of sensory attributes.
The Effect of Health Education with Leaflet Media on Improving Knowledge and Attitude of Tb Patients at Rotinsulu Pulmonary Hospital, Bandung Ardayani, Tri; Sitorus, Neti; Muwardi, Rudy Mulyana
Indonesian Journal of Health Research and Development Vol. 3 No. 3 (2025): Indonesian Journal of Health Research and Development
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/ijhrd.v3i3.325

Abstract

Background: Mycobacterium tuberculosis is the bacterium that causes tuberculosis, an infectious disease that targets the lungs, particularly the lung parenchyma.Aims: This study aims to increase the understanding and mindset of the patient's family about tuberculosis prevention therapy and other aspects of TB prevention and treatment through health education, especially by utilizing media such as leaflets.Methods: Pre-experiment design using the One Group Pre-test-Post-test research method is the type of study being conducted. There were 412 participants in this study. Using a purposive sampling technique, 30 persons made up the study's sample. A questionnaire was the tool utilized. The KEPK STIK Immanuel Bandung has recommended this study (No.132/KEPK/STIKI/XII/2021).Result: According to the study's findings, the majority of respondents had adequate understanding (80.0%) prior to receiving leaflets, and a good level of knowledge (83.3%) following leaflet distribution. The majority of respondents had a good attitude before receiving the leaflets (70.0%), and this attitude remained positive after receiving the leaflets (96.7%). Health Education Through Leaflet Media Has an Impact on TB Knowledge patients both prior to and following the operation. Health education using leaflet media has an impact on TB patients' attitudes both before and after the intervention. Conclusion: The findings indicate that health education via leaflet media has an impact on the attitudes and knowledge of patients with pulmonary tuberculosis. It is suggested that Rotinsulu Regional Hospital establish a regular health education program.
Metabolic Profile and Hepatoprotective Efficacy of Carica Papaya Leaves in CCl4 Induced Oxidative Stress Albino Mice Abdulkadir Usman, Maryam; Pantami, Hamza Ahmed; Sani, Muhammad Bappah; Lawan, Aliyu Ibrahim; Hamza, Hajjagana
Indonesian Journal of Health Research and Development Vol. 3 No. 3 (2025): Indonesian Journal of Health Research and Development
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/ijhrd.v3i3.369

Abstract

Background: Hepatic disorder is fatal and require vital medication, orthodox cure is deleterious, so there is need for natural curative agents.Aims: Bioactive phytochemical analysis and   efficacy of Carica papaya leaves extracts versus CCL4 induced oxidative stress in mice.Methods: The metabolite profile of Carica papaya leaves extract was analysed by LC-MS/MS analysis via GNPS. Liver aminotransferases were assessed, liver tissues and homogenates were assessed for histopathology and MDA, catalase, superoxide dismutase, and Glutathione S-Transferase activities, qRTPCR mRNA expression of hepatic tissue Glutathione S- Transferase was performed. Free radical scavenging activity of the extract were evaluated using invitro prototypes.Results: Numerous metabolites were identified from crude extract. Observed weight loss in rats, liver damage through elevating serum variables (marker enzymes and bilirubin), decrease in total protein and albumin. A significant decrease in tissue catalase, GST, and superoxide dismutase activities and marked increase in MDA level (p<0.05) were also observed. The extract effectively ameliorated CCl4 effects with marked decrease in serum variables. GST mRNA expression of hepatic tissue and histopathological results also supported the biochemical findings. Extract exhibited radical scavenging activity with DPPH IC50 of 0.56mg/ml, FRAP IC50 of 0.52mg/ml, H2O2 IC50 of 0.58mg/ml and Phosphomolybdenum IC50 of 0.62.Conclusion: Carica papaya leaves was beneficial in modulating the alterations induced in liver and serum variables of mice in CCL4 induced oxidative stress.
Comparative Phytochemicals Screening, Antibacterial and Antioxidant Properties of Some Selected Medicinal Plants in Nigeria Danjuma, Kabir
Indonesian Journal of Health Research and Development Vol. 3 No. 3 (2025): Indonesian Journal of Health Research and Development
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/ijhrd.v3i3.518

Abstract

Background: Antibiotics resistance poses serious health threats globally, necessitating the search and development of an efficient environmentally friendly antibiotics. Evaluation of medicinal plants possessing antioxidant and antimicrobial chemicals is essential for solving this problem and improves human health.Aims: This research was done to assess the phytochemical status, antioxidant and antibacterial potentials of the leaf extracts of four medicinal plants (Moringa oleifera, Linus usitatissimum, Vernonia amygdalina, and Anacardium occidentale) cultivated in Nigeria. Methods: Standard methods were used to screen the phytochemicals; agar well diffusion and DPPH radical scavenging assays were employed to evaluate the antibacterial and antioxidant properties of the extracts. Results: The results showed that the medicinal plants tested possessed significant phytochemicals including alkaloids, flavonoids, phenolics, terpenoids, tannins, saponins, among others. The plants showed effective antibacterial properties, with Moringa oleifera showing highest antibacterial activities against Staphylococcus aureus and Escherichia coli, followed by Vernonia amygdalina, Linus usitatissimum, and anacardium occidentale. The medicinal plants also showed powerful antioxidant potentials with lower IC50 values. moringa oleifera being the most powerful has an IC50 value of 41.95 µg/ml, followed by Linus usitatissimum (IC50 = 43.09 µg/ml), Vernonia amygdalina (IC50 = 54.64 µg/ml), and anacardium occidentale (IC50 = 66.85 µg/ml), compared with the standard ascorbic acid (IC50 = 14.14 µg/ml)). Conclusion: The medicinal plants tested in this study possess significant bioactive compounds and could serve as an effective potential agent against pathogenic bacteria, suppress oxidative stress thereby improving the human health quality.
Deep Learning-Based ResNet-50 Transfer Learning Approaches for Pneumonia Detection from Chest X-Ray Images: With and Without Fine-Tuning Rochmawati, Dwi Robiul; Maryani, Lidya
Indonesian Journal of Health Research and Development Vol. 3 No. 3 (2025): Indonesian Journal of Health Research and Development
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/ijhrd.v3i3.507

Abstract

Background: Pneumonia remains one of the leading causes of morbidity and mortality worldwide, particularly among children and older adults in low-resource settings. Diagnosis based on chest X-ray interpretation often depends on radiologist expertise, which may be limited in availability and prone to subjectivity. Deep learning offers a promising alternative to improve diagnostic efficiency and consistency.Aims: This study aims to evaluate the effectiveness of the ResNet-50 architecture for pneumonia detection using chest X-ray images by comparing transfer learning with frozen layers and partial fine-tuning strategies.Methods: A total of 5,856 chest X-ray images were obtained from a public dataset and divided into training, validation, and testing sets using stratified sampling. Data preprocessing included resizing, normalization, and augmentation. Two models were developed: (1) a frozen ResNet-50 model, where all convolutional layers were fixed, and (2) a fine-tuned ResNet-50 model, where the final convolutional layers were retrained. Performance was evaluated using accuracy, precision, recall, F1-score, and area under the ROC curve (AUC). Statistical tests were conducted to assess performance differences between the two models.Results: The frozen model achieved an accuracy of 62.50% and an AUC of 0.4819, indicating weak classification performance. In contrast, the fine-tuned model demonstrated substantially higher accuracy of 85.90%, F1-score of 0.8967, and AUC of 0.9510, showing strong discriminative capability. Statistical analysis confirmed that the performance improvement in accuracy was significant.Conclusion: Fine-tuning significantly enhances the applicability of ResNet-50 for pneumonia detection. Without feature adaptation, pretrained models struggle to generalize to medical imaging domains. Fine-tuned transfer learning provides a more reliable framework for developing computer-aided diagnostic systems, particularly in clinical environments with limited expert availability.
Stem Cell Research Awareness and Perception in Nigeria: Inferences from Sickle Cell Advocacy Centers in Kano and Lagos Usoh, Akon Ekpenyong; Yusuf, Jamiu Adeniyi
Indonesian Journal of Health Research and Development Vol. 4 No. 1 (2026): Indonesian Journal of Health Research and Development
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/ijhrd.v4i1.517

Abstract

Abstract Background: Sickle cell disease (SCD) remains a critical public health challenge in Nigeria, particularly in Lagos and Kano, where prevalence is high. Although hematopoietic stem cell transplantation (HSCT) is an advancing global cure, awareness and acceptance of stem cell therapies in Nigeria are alarmingly low.Aims: This study examines public knowledge and attitudes toward stem cell research and treatments in Lagos and Kano. It also explores barriers to acceptance and evaluates the role of advocacy and institutional programs in promoting awareness.Methods: A mixed-method approach was adopted. Quantitative data were collected from 400 respondents using structured questionnaires, while qualitative insights came from key informant interviews with healthcare professionals and advocacy staff. Four SCD centers were also assessed for their stem cell awareness programs.Result: Findings show that only 32.5% of Lagos respondents and 18.7% of Kano respondents had prior awareness of stem cell research, with far fewer demonstrating accurate knowledge of its applications and safety. Major barriers to acceptance include cultural beliefs, ethical concerns, financial constraints, and misinformation. Of the four centers evaluated, only one had a structured awareness program, while advocacy efforts were hindered by inadequate funding, limited technical training, and weak engagement with healthcare institutions.Conclusion: Public awareness of stem cell therapies in Nigeria is critically low. Strengthening advocacy capacity, implementing targeted education campaigns, and expanding government support through policy and financing are essential to improve access, acceptance, and utilization of novel stem cell treatments for SCD.
Implementation of SBAR Communication among Nurses during Handover between Shifts before and after a Mini Seminar in the Mawar Inpatient Ward, West Kalimantan Yogi, Ignasius; Lidya Maryani
Indonesian Journal of Health Research and Development Vol. 4 No. 1 (2026): Indonesian Journal of Health Research and Development
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/ijhrd.v4i1.526

Abstract

Delayed care processes, lack of attention, and limited knowledge in receiving patient information often lead to poor communication among nurses. The World Health Organization recommends SBAR (Situation, Background, Assessment, Recommendation) as a structured communication tool to convey critical information requiring immediate action. This study aimed to determine the implementation of SBAR communication among nurses during handovers between shifts before and after a mini seminar in the Mawar Inpatient Ward, West Kalimantan. A pre-experimental design with a one-group pretest–posttest approach was applied and described descriptively. The results showed that before the mini seminar, 50% of respondents applied SBAR communication incorrectly, while 50% applied it correctly. After the mini seminar, there was a significant improvement, with 100% of respondents applying SBAR communication appropriately. These findings indicate that the mini seminar successfully improved the implementation of SBAR communication among nurses during shift handovers. In conclusion, the mini seminar was proven to enhance the professionalism of nursing services by optimizing communication, reducing the risk of medical errors, and supporting better quality of care in the inpatient ward.
Phytochemical Screening and Antimicrobial Activity of Phyllanthus Amarus Leaves (Stone Breaker) Against Some Selected Microorganisms Lawan, Imrana; Suwaiba Abba Ismail; Aminu Baita; Zeenatu Ali Baba
Indonesian Journal of Health Research and Development Vol. 4 No. 1 (2026): Indonesian Journal of Health Research and Development
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/ijhrd.v4i1.535

Abstract

BACKGROUND: Phyllanthus amarus is among the most significant medicinal plants found in tropical and subtropical regions, commonly used in the treatment of diseases affecting the stomach, liver, kidneys, and spleen. This study aimed to identify the phytochemical constituents and evaluate the antimicrobial activities of the leaves of Phyllanthus amarus METHOD: The powdered leaf sample was extracted using ethanol at a sample-solvent ratio of 1:3. The resulting crude extract was then fractionated using four different solvents: petroleum ether, chloroform, acetone, and methanol. Each of the four fractions was subsequently subjected to phytochemical screening and antimicrobial activity evaluation. RESULTS: The results indicated that the plant leaves contained all the phytochemicals tested. The petroleum ether fraction showed the presence of all the phytochemical constituents. The chloroform fraction contained alkaloids, saponins, polyphenols, and glycosides only. The acetone fraction exhibited all the phytochemicals except saponins, polyphenols, and terpenoids, while the methanol fraction contained alkaloids, steroids, polyphenols, and glycosides. Antimicrobial analysis revealed zones of inhibition against the tested organisms, with the chloroform fraction demonstrating the highest activity. These findings suggest that the plant possesses both physiological and medicinal significance for humans, consistent with previous research reports CONCLUTION: The antimicrobial evaluation of four fractions showed zones of inhibition on the tested organisms, which verified their uses in the treatment of various ailments may be attributable to some of its phytochemical constituents with high drug properties.
Health Beliefs, Illness Perceptions, and Self-Management Behaviors in Hypertension Clients Jauhar, Muhamad; Ririn Widyasari; Heny Siswanti; Novi Tiara
Indonesian Journal of Health Research and Development Vol. 4 No. 1 (2026): Indonesian Journal of Health Research and Development
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/ijhrd.v4i1.537

Abstract

Background: Hypertension is a health problem that impacts all age groups and social backgrounds, with the risk of serious complications, reduced quality of life, and a huge burden for clients, families, and the country. The increasing number of hypertension cases requires serious attention to reduce its impact.Aims: This study analyzes the relationship between health beliefs disease perceptions and self-management behavior in hypertensive clients at the Juwana Community Health Center.Methods: This research used a cross-sectional design and involved 95 clients selected using purposive sampling. Data was collected through a valid and reliable questionnaire and then analyzed using the Spearman-Rho correlation testResult: The results showed a significant relationship between health beliefs and self-management behavior (r = 0.327; p = 0.001), while the relationship between illness perception and self-management was insignificant (r = 0.178; p = 0.083). The majority of clients had sufficient categories for health beliefs (74%), disease perceptions (81.3%), and self-management behavior (71.9%).Conclusion: In conclusion, health beliefs influence self-management behavior, while illness perceptions do not have a significant relationship. Interactive media-based educational programs are needed to increase health confidence and support self-management of hypertension patients.
Acute Ischemic Stroke Following A Single Wasp Sting: The Impact of Early Intensive Multidisciplinary Rehabilitation (A Case Study): A Rare Presentation with Favorable Rehabilitation Outcome K, Sasirekha; J, Priya; B, Ganesan; B, Arun
Indonesian Journal of Health Research and Development Vol. 4 No. 1 (2026): Indonesian Journal of Health Research and Development
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/ijhrd.v4i1.592

Abstract

Background: Cerebrovascular accidents following Hymenoptera stings are exceptionally rare, with most reported cases involving multiple stings. This case study presents an unique case of acute ischemic stroke triggered by a single wasp sting and highlights the critical role of early intensive physiotherapy in achieving excellent functional recovery.Case Presentation: A 55-year-old previously healthy electricity lineman sustained a single wasp sting over the neck. After initial symptomatic treatment at a primary health center, he returned to work but collapsed within two hours, presenting with right side weakness, mild aphasia, and apraxia. Brain imaging showed subtle small-vessel ischemic changes without large-vessel occlusion. Extensive thrombophilia and cardioembolic workups were normal. The stroke was attributed to venom-induced vasospasm and inflammatory/thrombogenic effects. The patient was managed with intravenous corticosteroids, dual antiplatelet therapy, and low-molecular-weight heparin. Structured inpatient physiotherapy commenced on the patient who stays in the wards, good progression was noted as the day passes.Results: At the time of discharge the patient was walked with minimal assistance. At one-month follow-up, he achieved modified independence in activities of daily living, with ongoing gradual recovery of hand function. Functional Independence Measure (FIM) on admission it was 13, later it improved to 39 at the time of discharge, and the follow-up of the patient rose to 52. scores improved markedly since the admission to the follow-up.Conclusion: This case demonstrates that even a single wasp sting can precipitate acute ischemic stroke via vasospasm and inflammation. Prompt medical stabilization combined with early, intensive, goal-directed physiotherapy can yield rapid and substantial functional recovery.

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