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Journal Of Carbazon
Published by Universitas Syiah Kuala
ISSN : 29885744     EISSN : 29885744     DOI : 10.24815/jocarbazon
Core Subject : Science,
Biochemistry, Genetics & Molecular Biology Chemistry Materials Science & Nanotechnology
Journal of Carbazon is a journal published by Chemistry Department, Faculty of Science and Mathematics, USK Banda Aceh. The journal aims to disseminate cutting-edge research in all areas of chemistry both theoretical and experimental studies. Journal of Carbazon provides readers with original research articles and reviews. We welcome articles coming from Indonesia and overseas, capturing the rapid development of chemistry, including: Theoretical and computation chemistry Environmental chemistry Material, composite and polymer chemistry Organic synthesis and natural product chemistry Inorganic Chemistry Food and medical chemistry Biochemistry Analytical chemistry The author is solely responsible for the content of published articles and understood that submitted work is based on original results which has not been published previously. All accepted articles are reviewed by a team of experts.
Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)
Articles 25 Documents
 1   2   3 
Characterization of Thermophilic Novel-Rare Actinobacteria from Hot Springs and Compost as an Unique Secondary Metabolite Producer Maghfirah, Ruhul; Kemala, Pati; Astryna, Syarifah Yanti
Journal of Carbazon Vol 2, No 2 (2024): December 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v2i2.42883

Abstract

This review aims to explain in more detail about the Actinobacteria and it secondary metabolites. Some species of Actinobacteria can live in extreme environments such as high acid, high base, high salt and even high temperatures. Actinobacteria mainly of the genus Streptomyces sp. has been known to produce bioactive compounds such as antibacterial, antifungal, anticancer, antitumor, anticytotoxic, anti-inflammatory, anti-parasitic, anti-malarial, antiviral and antioxidant. This study reviews various research findings on Actinobacteria species and their ability to thrive in extreme environments. It also reviews the findings of bioactive compounds isolated from Actinobacteria and their potential applications. Some species in the genera Streptomyces, Thermonospora, and Thermoactinomyces have optimal growth temperatures above 55C and are categorized as thermophilic. More than 30,000 bioactive compounds that have been isolated are derived from Actinobacteria and 80% are from the genus Streptomyces sp. Benzastatin C and 3-Chloro-Tetrahidroquinolon are new antivirals isolated from Streptomyces nitrosporeus. Essramycin is a novel antibiotic that shows activity against Gram positive and Gram negative bacteria. Chandrananimycin A isolated from Actinomadura sp. and N-(2-hydroxyphenyl)-2-Phenazinamin (NHP) isolated from Nocardia dassonvillei are novel antibiotics that can be used as antifungals, antialgas, antibacterials and anticancer. The potential of Actinobacteria in producing bioactive compounds can advance the field of science and technology in the future and become an alternative to overcome the problem of resistance to pathogenic microorganisms are increasing.
The potential of fly ash-based geopolymers as an environmentally friendly construction material solution: A review Mazwan, Mazwan; Fajri, Fajri
Journal of Carbazon Vol 2, No 2 (2024): December 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v2i2.43510

Abstract

The use of environmentally friendly construction materials has been increasing in response to the demand for sustainable development. Fly ash-based geopolymers have emerged as an innovative and sustainable solution in the construction industry. This article discusses the potential use of fly ash-based geopolymers, covering their characteristics, synthesis process, advantages, challenges, and future development prospects. This research adopts a literature review approach, referencing various international and national journals. The study findings reveal that fly ash geopolymers possess high mechanical strength, corrosion resistance, and significantly lower carbon emissions compared to conventional concrete. This potential provides significant opportunities in supporting more environmentally friendly infrastructure development.
Montmorillonite-Chitosan as a Biocomposite Encapsulation for Ibuprofen in Drug Release Afifi, Muhammad Ridho; Irwandi, Dodi; Safitri, Eka; Syafei, Dedri; Ngapa, Yulius Dala
Journal of Carbazon Vol 2, No 2 (2024): December 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v2i2.42149

Abstract

Ibuprofen is a type of anti-inflammatory drug. However, its use faces challenges in the medical field due to its rapid degradation, low bioavailability, limited solubility, and high permeability. One approach to address these issues is the encapsulation of ibuprofen by coating it with Montmorillonite (MMT) and Chitosan (CS) to control the released dosages of Ibuprofen. MMT and CS were used to coat ibuprofen using four methods. These methods were compared through dispersing MMT in water, mixing with chitosan, and combining ibuprofen under different conditions. Subsequently, tests were conducted on ibuprofen coated with MMT-CS, including morphology, efficiency, and release profile. The most effective method for controlling ibuprofen release was shown in the third method, where MMT-CS was first modified, and then ibuprofen was added to the modified MMT-CS. This method showed the highest encapsulation efficiency of 61.51%, the best release profile with 21.59% ibuprofen release within 90 minutes, and the most uniform encapsulation morphology. These studies indicated that the MMT-CS biocomposite effectively improves ibuprofen release efficiency, potentially enhancing therapeutic outcomes while reducing side effects of ibuprofen.
Modification of Montmorillonite with Chitosan as Mercury Metal Adsorbent Julinawati, Julinawati; Nisa, Salasatun; Fathurrahmi, Fathurrahmi; Mustafa, Irfan; Saleha, Sitti; MZ., Kartika; Suryati, Suryati
Journal of Carbazon Vol 2, No 2 (2024): December 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v2i2.42230

Abstract

Modification of montmorillonite with chitosan as an adsorbent of mercury (Hg) metal has been carried out. This study aims to determine the characteristics of the adsorbent, the optimum adsorption capacity of Hg metal, and its adsorption isotherm equation. The optimum conditions for Hg metal adsorption are determined by varying the contact time and pH of the solution. Variations in adsorbate concentration are carried out to determine the adsorption isotherm. Characterization of the adsorbent using FTIR shows the presence of -OH, Si-O, Al-O, C-C, and N-H groups. The optimum conditions for mercury metal adsorption by montmorillonite modified with chitosan occur at a contact time of 80 minutes, and a pH of 4. The adsorption process of mercury metal ions using montmorillonite adsorbent modified with chitosan satisfies both isotherm models, namely the Langmuir and Freundlich isotherms with R2 values of 0.971 and 0.967 respectively, and a maximum adsorption capacity of 13.513 mg/g. The regeneration test showed that the adsorbent can be reused for the absorption of mercury metal ions.
Evaluation of Antifeedant Activity in Methanol Extracts of Zingiberaceae Species Against Epilachna sparsa Purnama, Agnia; Nurdin, Nurdin; Ratna, Ratna; Farida, Mutia
Journal of Carbazon Vol 2, No 2 (2024): December 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v2i2.42458

Abstract

Cellulosenanofibrils (CNF) is a new generation material that has high performance, good physics and medical properties and is a renewable material that has been developed from various sources using the acid hydrolysis method. CNF synthesis is generally obtained from logs that have a high amount of cellulose fiber. Cellulose nanofibrils (CNF) from arabica coffee skins have great potential to be developed as raw materials for medicines, which function as wound healing agents, surgical sutures, diet medicines, and skin softeners. CNF is produced from Arabica coffee skin through delignification, namely the removal of lignin and hemicellulose by extraction with alkali until -cellulose is obtained, then CNF is synthesized through hydrolysis using dilute acid. From the coffee skin extraction results, a high cellulose yield was obtained, reaching above 24.30% and crystallinity reaching 79.60%. Hydrolysis by 10%, 12% and 15% HCl with a reaction time of 2 hours, the respective crystallinity was 80.66; 79.06; and 77.69%.
Comparison of Blood Glucose Testing Methods: Analyzer, Glucometer, and Spectrophotometer at Kuta Alam Health Center Putri, Safridha Kemala; Fajarna, Farah; Ulya, Rozatul
Journal of Carbazon Vol 3, No 1 (2025): June 2025
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v3i1.43627

Abstract

Blood glucose, a form of sugar present in the bloodstream, is derived from dietary carbohydrates and stored as glycogen in the liver and skeletal muscles. Blood glucose levels of 140 mg/dL in random testing or 120 mg/dL in fasting tests the indication of diabetes mellitus (DM). According to the World Health Organization (WHO) in 2021, DM is among the top ten leading causes of death globally. Blood glucose levels can be measured using various methods, including chemistry analyzers, glucometers, and spectrophotometers. This study aims to evaluate the differences in blood glucose levels obtained using these three analytical methods. The study aims to compare blood glucose levels measured using a chemistry analyzer, glucometer, and spectrophotometer. A descriptive research method was applied, with samples collected through random sampling, comprising 25 normal and 25 elevated blood glucose level samples. The majority of participants were women (76.0 %, n=38), while men represented 24.0 % (n=12), with an average participant age of 57.8 years. In the normal group, blood glucose levels measured using the chemistry analyzer ranged from 72 mg/dL to 116 mg/dL, with a mean of 90.52 mg/dL. Measurements using the glucometer showed a range of 75 mg/dL to 129 mg/dL, with a mean of 95.88 mg/dL, while the spectrophotometer results ranged from 74 mg/dL to 120 mg/dL, with a mean of 93.00 mg/dL. In the high blood glucose group, measurements using the chemistry analyzer ranged from 195 mg/dL to 342 mg/dL, with a mean value of 272.04 mg/dL. Measurements with the glucometer ranged from 200 mg/dL to 358 mg/dL, with a mean value of 278.44 mg/dL, while the spectrophotometer results ranged from 199 mg/dL to 354 mg/dL, with a mean value of 275.48 mg/dL. Based on the results, the chemistry analyzer demonstrated higher precision and accuracy in measuring blood glucose levels compared to the glucometer and spectrophotometer.
Preparation and Synthesis of Activated Carbon From Areca Nut Shell Coated with Nanochitosan From Shrimp Shell Herlinawati, Herlinawati; Fildzah, Qisthina; Sihombing, Junifa Layla; Kembaren, Agus
Journal of Carbazon Vol 3, No 1 (2025): June 2025
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v3i1.45959

Abstract

This study aims to determine the manufacture of adsorbents made from activated carbon areca nut shell coated with nanochitosan from shrimp shells. The carbon from the areca nut shell was obtained by heating process using a temperature of 300oC. The carbon obtained is activated with H2SO4 and then modified by coating activated carbon with nanochitosan. Chitosan was prepare through isolation the stages of deproteinization, demineralization, and deacetylation. Chitosan will be characterized using FTIR. The change in size of chitosan to nano chitosan was evaluated by ionic gelation method with 1% NaTPP. The nanochitosan obtained will be characterized using PSA. The results of FTIR characterization showed the presence of an N-H group at a wave number of 3345.89 cm-1. PSA characterization gave a result that the particle size of shrimp shell chitosan was nano-sized, which was 51.11 nm.
Synthesis of schiff base from dialdehyde breadfruit (Artocarpus altilis) starch and aniline with antibacterial properties Zuhra, Cut Fatimah; Damanik, Rianto
Journal of Carbazon Vol 3, No 1 (2025): June 2025
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v3i1.46044

Abstract

Schiff bases were successfully synthesized via a condensation reaction between dialdehyde starch (DAS), derived from breadfruit (Artocarpus altilis) starch, and aniline. DAS was prepared through oxidative cleavage of the vicinal diol groups in native starch using sodium periodate. The formation of DAS was confirmed qualitatively by the appearance of a brick-red precipitate upon addition of Fehlings reagent and a marked increase in its water solubility. Fourier Transform Infrared (FT-IR) spectroscopy revealed a strong absorption band at 1635.64 cm, corresponding to the aldehyde C=O stretching vibration, supporting the successful oxidation. The oxidized starch showed a high degree of oxidation (80.9%) and a carbonyl content of 10.36%. Condensation between the aldehyde groups of DAS and the amino group of aniline resulted in the formation of a Schiff base. FT-IR analysis of the resulting compound revealed absorption bands at 1635.64 cm and 1604.77 cm, indicating the formation of imine (-C=N-) bonds, while a peak at 871.82 cm confirmed the presence of aromatic ring structures. The antibacterial activity of the synthesized Schiff base was evaluated using the disk diffusion method, showing strong inhibitory effects against Escherichia coli and Staphylococcus aureus. These findings showed that starch-based Schiff bases represent a promising class of biodegradable antibacterial agents with potential applications in biomedicine and biomaterials.
Silica Composite Materials for Enhanced Arsenic Adsorption in Water Treatment Applications : A Review Afdhila, Rizqa; Azizah, Nur
Journal of Carbazon Vol 3, No 1 (2025): June 2025
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v3i1.46234

Abstract

Arsenic contamination in water is a critical environmental concern due to its high toxicity and persistence, posing serious risks to human health and ecosystems. Adsorption is considered one of the most efficient and cost-effective methods for arsenic removal, especially using composite adsorbents. This study evaluates several silica-based composite adsorbents designed to enhance arsenic removal from aqueous solutions. The composites combine silica with various functional materials, including iron oxide, iron(III) nitrate, iron(III) chloride, manganese, magnesium, activated carbon, and polyamines, aiming to improve adsorption capacity, selectivity, thermal stability, and reusability. Adsorption performance was assessed under varying pH levels, adsorbent dosages, contact times, initial arsenic concentrations, and temperatures. Among the tested materials, the iron oxide loaded silica (IOLS) composite (silica, iron(II) sulfate, and iron(III) chloride) exhibited the highest As(III) adsorption capacity of 82.4 mg/g at pH 7 with 90 minutes contact time. Meanwhile, the ironmanganese oxide incorporated rice husk silica (FMRS-2) composite (silica, iron oxide, and manganese) achieved an As(V) adsorption capacity of 20.3 mg/g at pH 7 after 24 hours, with 100% removal efficiency sustained over four regeneration cycles.
Antibacterial Activity Of Neem (Azadirachta indica A. Juss) Essential Oil Obtained By The Enfleuration Method Against Propionibacterium acnes Bacteria In Liquid Soap Formula Nasution, Rosnani; Bahi, Muhammad; Marianne, Marianne; Hadisah, Dara
Journal of Carbazon Vol 3, No 1 (2025): June 2025
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v3i1.46643

Abstract

This research was conducted to determine the antibacterial activity of Azadirachta indica flower essential oil and its liquid soap formulation against P. acnes bacteria and to determine the quality of the liquid soap formulation. The essential oil of A. indica flower was obtained by the enfleuration method, the yield was a concentrated yellow essential oil with a yield of 2.151%, a density of 0.892 g/mL, solubility in ethanol 90%, 1:1, clear; and a refractive index of 1.435 which complies with the Indonesian National Standard (SNI). Furthermore, essential oils are formulated into liquid soap preparations and tested for physical quality and antibacterial activity. The liquid soap formulation had a distinctive odor of A. indica flowers, and homogen. The antibacterial activity against P. acnes bacteria, was the inhibitory value of A. indica flower liquid soap was higher than A. indica flower essential oil with the highest liquid soap inhibition power of 52%, while the inhibitory power of essential oil was 51% with each concentration of 2.5%, which was compared to its positive control, namely chloramphenicol. The quality testing of liquid soap is accordance with SNI 06-4085-1996, pH values ranging from 8.48 9.67 meet SNI (8-11), viscosity values ranging from 1504.4 cP 2369.7 cP meet SNI (400-4000 cPs), and foam height values ranging from 7.1 cm 8.3 cm. The results of the GC MS analysis of A. indica essential oil showed that the dominant compound was -Copaene (15.84%).

Page 2 of 3 | Total Record : 25

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