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Jurnal MedScientiae
Published by Universitas Kristen Krida Wacana
ISSN : -     EISSN : 28291166     DOI : https://doi.org/10.36452/jmedscientiae
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Jurnal MedScientiae adalah jurnal yang dikelola oleh Fakultas Kedokteran dan Ilmu Kesehatan Universitas Kristen Krida Wacana. Jurnal ini mempublikasikan artikel-artikel secara open access dalam lingkup bidang kedokteran dan kesehatan seperti kedokteran dasar, bioetika kedokteran, biologi sel, biologi molekuler, genetika, fisiologi, biokimia, bioinformatika, anatomi, farmakologi, kesehatan masyarakat, dan ilmu biomedik lainnya. Tim editorial menerima naskah berupa artikel penelitian, literature dan systematic review, dan laporan kasus. Naskah yang dikirimkan hendaknya belum pernah diterbitkan sebelumnya di jurnal maupun media yang lain dan disiapkan sesuai dengan template atau format yang telah ditentukan. Setiap naskah yang memenuhi kriteria jurnal akan direview oleh pakar yang sesuai (peer reviewer). Jurnal MedScientiae tidak mengenakan biaya selama proses mulai dari penerimaan naskah hingga publikasi. Jurnal MedScientiae terbit 3 kali dalam satu tahun, yaitu pada bulan April, Agustus dan Desember dengan cakupan keilmuan yang telah disebutkan di atas. Edisi pertama jurnal akan diterbikan di bulan Mei tahun 2022 dengan nomor ISSN 2829-1166.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 219 Documents
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Rasionalitas Penggunaan Obat Benzodiazepine oleh Dokter Selama 10 Tahun Terakhir: Sebuah Literature Review Anughrahani, Lilie; Wijaya, Diana; Ndraha, Suzanna; Rumawas, Marina Astrid
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3651

Abstract

Mental disorders have become a common problem globally. The World Health Organization shows that more than one in six people experienced mental health problems in 2016. Benzodiazepines, a drug that has been on the market since 1957, are often used to treat mental and behavior-related problems. Although effective for certain conditions, long-term use of benzodiazepines can cause significant side effects. Health regulations and guidelines suggest that treatment with benzodiazepines should be carried out rationally with reference to the Decree of the Minister of Health of the Republic of Indonesia in 2021 concerning the National Formulary. This literature aims to conduct a review to evaluate the rationality of the use of benzodiazepines by doctors in various countries over the past ten years. The method in this study is to search for articles through Google Scholar and Pubmed. The results obtained were that benzodiazepines are generally used to treat anxiety and sleep disorders. The maximum dose, which is according to the national formulary and the Food and Drug Administration, does not have a significant difference. Challenges that need to be addressed involve aspects of prescribing, such as ensuring the recipe is in accordance with the right indications, adhering to dosage restrictions, and paying attention to the maximum duration of use. Therefore, there needs to be clear rules to regulate this, supported by active socialization efforts to increase doctors' understanding and compliance with more rational prescribing practices.  
The Prevalence Rate Of Anisometropia Among Students Of FKIK Ukrida Class 2023 Ramadhan, Dafa Zahara; FarFar, Inggrid Osya
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3675

Abstract

Anisometropia is a different refractive power between the two eyes. Anisometropia can cause various symptoms, such as eye fatigue, headaches, blurred vision, diplopia (double vision), and decreased depth of vision (stereopsis). This will definitely interfere with learning activities, especially in college students. Purpose: This study aims to determine the prevalence and characteristics of anisometropia in university students. Methods: This study used total sampling technique with cross sectional method with 150 patients as respondents. Data collection time in this study was conducted from August 2023 to September 2023. Results: In this study as many as 66.7% (100 people) experienced anisometropia. A total of 12.7% (19 people) experienced simple myopic anisometropia, as many as 2% (3 people) experienced simple hypermetropic anisometropia, as many as 8% (12 people) experienced simple myopic astigmatism, as many as 12% (18 people) experienced compound myopic anisometropia, as many as 31.3% (47 people) experienced compound myopic astigmatism anisometropia, as many as 7% (1 person) experienced mixed anisometropia. Conclusion: The prevalence of anisometropia in this study was 66.7% (100 people). The most common type of anisometropia in this study is compound myopic astigmatism. From this study, it is hoped that it can increase public awareness to carry out sharp vision checks early on, so that learning activities can be more effective.
Prevalensi Akomodasi Insufisiensi pada Mahasiswa Fakultas Kedokteran dan Ilmu Kesehatan UKRIDA Angkatan 2023 Gosali, Vincentio Owen; Farfar, Inggrid Osya; Silaen, Desi Hartati
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3690

Abstract

Accommodation insufficiency is an accommodation disorder characterized by a lower accommodation amplitude than the minimum limit of the Hofstetter formula. Symptoms of accommodation are impaired near vision, asthenopia (eye fatigue), blur, headache, and visual discomfort. This study aims to determine the prevalence of accommodation insufficiency in FKIK UKRIDA students class of 2023.  This study used descriptive quantitative research method and cross sectional research design with 150 respondents. Each subject was only observed once at the same time using the RAF Rule as a measuring instrument. Data collection was carried out from September to November.  The prevalence of accommodation insufficiency in FKIK UKRIDA Batch 2023 students amounted to 2 people (1.3%) in both eyes, 6 people (4%) in the left eye, and 2 people (1.3%) in the right eye.  Accommodation disorders can be influenced by age and refraction. The prevalence of accommodation insufficiency in FKIK UKRIDA students of 2023 is 1.3%. The highest number who experienced accommodation insufficiency was in the left eye, which was 4%. It is recommended that people pay more attention to their eye health by conducting routine eye examinations every 6 months-1 year.
Tinjauan Pustaka Terbaru Peran Omega 3 Pada Dry Eye Anugrahsari, Santi; Lesmana, Andri; Korwa, Daniela Dirgantari; Kumala Sari, Ni Putu Winda
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3707

Abstract

Dry eye disease (DED) or dry eye disease is a common condition in every country. Dry eyes can cause symptoms such as discomfort or a cycling sensation, red eyes and a feeling of blockage. Inflammation is one of the underlying pathophysiology of dry eyes. One of the therapeutic approaches that has received major attention is the use of omega-3 fatty acid supplements, which are known to have anti-inflammatory properties and can support eye health. Recent studies have shown that omega-3, especially EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), can improve tear quality, improve meibomian gland function, and increase tear production in people with dry eyes. In addition, omega-3 also plays a role in reducing symptoms of dry eyes, although several studies have shown significant results, but the effectiveness of omega-3 in managing dry eyes still requires further research, especially in determining the optimal dose and duration of therapy. This literature review aims to review the latest developments related to the role of omega-3 in dry eye therapy and explore the underlying effects of omega-3 on dry eyes. Further research is expected to provide stronger evidence regarding the role of omega-3 in dry eye therapy.
Prediktor Mortalitas Pasien Sindrom Koroner Akut di Rumah Sakit X Jakarta Periode September 2023-2024 Rante Tiku, Ristha Monica; Arsita, Elli; Oktavia, Eva
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3721

Abstract

Acute coronary syndrome (ACS) is the leading cause of death from heart disease worldwide. Several studies have identified risk factors that increase mortality among ACS patients, including advanced age, type 2 diabetes mellitus, and chronic kidney disease. This study aims to evaluate the association between these risk factors and mortality in ACS patients at Hospital X Jakarta between September 2023 and September 2024. Contains This study used a retrospective cohort design with analysis of medical record data of patients with ACS. Statistical analysis was performed using chi-squared and Fisher's exact tests to determine the association of age, type 2 diabetes mellitus, and chronic kidney disease with mortality in patients with ACS. Contains A total of 84 patients with a mean age of 59.49 years met the study criteria. The majority of patients had NSTEMI (61.9%) and 56% had type 2 diabetes mellitus. Mortality occurred in 4.8% of the patients. The results of the analysis showed that advanced age (≥60 years) was significantly associated with mortality in SCA patients (p=0.047; RR=4.50). Chronic kidney disease was also significantly associated with mortality (p=0.011; RR=8.16). However, type 2 diabetes mellitus did not show a significant association with mortality (p=0.092). Advanced age and chronic kidney disease were significant predictors of mortality in patients with ACS, whereas type 2 diabetes mellitus was not significantly associated with mortality.  
Hubungan Pola Makan dengan Penyakit Kanker Kolorektal Firman Riscky Mansyur; Angeline, Reni; Christina, Shintia; Kertadjaya, Wiwi
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3741

Abstract

Cancer is the second leading cause of death globally. Colorectal cancer is one of the most common cancers worldwide. Referring to GLOBOCAN data, in general colorectal cancer is the third highest incidence of cancer after lung cancer and breast cancer. This is attributed to the diet that affects colorectal cancer. Most colorectal cancer are still closely related to genetics. In addition to genetic factors, food intake factors also closely related to colorectal cancer. Current research shows colorectal cancer occurs due to genetic mutations and inflammatory bowel disease. This literature review uses a Literature review design using a search method with a library of research articles or journals through PubMed and other journal sources. The results of the literature review are associated with dietary pattern that affect colorectal cancer, red mead intake is related to the growth of colorectal cancer, while high fiber food can help reduce the risk of colorectal cancer.
Pengaruh Aktivitas Fisik Terhadap Kecepatan Waktu Reaksi pada Unit Kegiatan Mahasiswa Futsal UKRIDA 2023 Yazmin, Aneta Almira; Rumiati, Flora; Evan, Evan
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3743

Abstract

Reaction time is the duration between an individual receiving a stimulus and the formation of a motor response to that stimulus. One effective method to enhance reaction time is through regular physical activity. Exercise has the potential to increase blood and oxygen flow to skeletal muscles and the brain which can affect a person's reaction time. This study aims to determine the average reaction time before and after physical activity and explore the influence of reaction time on the amount of exercise among respondents. The research adopts a quantitative experimental approach with a one-group pre and post-test design. The total sampling method involves 36 respondents who meet inclusion and exclusion criteria. The findings, analyzed using the Wilcoxon test with p=0.00 (p>0.05), indicate a significant impact of physical activity on the reaction time speed in the student futsal unit of the Faculty of Medicine at Kristen Krida Wacana University in 2023. This research serves as a reference for the community, highlighting the importance of regular physical exercise to improve reaction time. A faster reaction time enables individuals to respond more efficiently and make accurate decisions in a short period during various activities.
Efektivitas Efektivitas Toilet Seat Sanitizer terhadap Bakteri Escherichia coli Penghasil Extended-Spectrum Beta-Lactamase: Escherichia coli Penghasil Extended-Spectrum Beta-Lactamase Pasaribu, Donna Mesina; Gunardi, Wani Devita; Andini , Natasya Johanna
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3745

Abstract

The toilet is one of the facilities provided to meet the needs of users with various backgrounds of different hygiene behavior, so that they can be a source of bacterial transmission, one of which is Escherichia coli (E.coli), which is resistant to producing Extended-Spectrum Beta-Lactamase (ESBL). E.coli producing ESBL can cause infection of various diseases, to overcome this, preventive measures are taken to reduce the level of risk transmission through the use of toilet seat sanitizers. This study aims to determine the effectiveness of toilet seat sanitizer against E.coli producing ESBL. This research is a descriptive observational laboratory study using a toilet seat sanitizer with an active substance of 50%-Benzalkonium Chloride and Ethyl Alcohol 96% against E.coli producing ESBL American Type Culture Collection (ATCC) 35218. The phenol coefficient test was used to measure the effectiveness of the toilet seat sanitizer was compared with phenol, Minimum Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC) were tested using the tube method. This study showed that the coefficient of toilet seat sanitizer effective against E.coli producing ESBL was 4,5. MIC active substance toilet seat sanitizer is effective at a concentration of 0,3125%, and MBC at a concentration of 0,625%. The author concludes that the results of the MIC and MBC prove that a toilet seat sanitizer active substances 50%-Benzalkonium Chloride and Ethyl Alcohol 96% is effective as a disinfectant against E.coli producing ESBL ATCC 35218.
Analysis of Factors Influencing Low Back Pain (LBP) Complaints in Convection Tailors Pademangan North Winata, Susanty Dewi; Fuk, Liem Jen; Sutanti, Yosephin Sri; Lau, Denice
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3775

Abstract

Low back pain is a disorder of the musculoskeletal system caused by ergonomic exposure, including improper work posture, sitting too long, and excessive activity. Purpose: This study aims to examine the relationship between work posture, age, length of service, gender, body mass index, last level of education, and smoking habits with LBP complaints in garment sewing workers in the Pademangan area, North Jakarta, in 2024. The research design used in this study was cross-sectional and took place in November 2024. Individual characteristics, job information, and LBP complaints were obtained from the Nordic Questionnaire about lower back problems, while the respondents' work postures were obtained using RULA (Rapid Upper Extremity Assessment). Data were analyzed using the Chi-Square test method. A total of 44 respondents (58.7%) showed unergonomic work postures based on the RULA score, and 37 respondents (49.3%) reported LBP complaints. The results of the analysis found a significant relationship between length of service and LBP complaints. Respondents with more than 5 years of work experience tend to experience LBP complaints more often than respondents with less than 5 years of work experience. Ergonomic work posture control is essential to prevent and reduce LBP complaints.
The Prevalence of Refractive Errors in Elementary School Children at SDN 16 and 17 Duri Kepa, West Jakarta, 2023/2024: Prevalensi Kelainan Refraksi Mata Pada Anak Usia Sekolah Dasar di SDN 16 dan 17 Duri Kepa Jakarta Barat 2023/2024 Da Costa, Sandra Aparasiba; Silaen, Desi Hartati; Farfar, Inggrid Osya
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3834

Abstract

Refractive eye disorders are common among elementary school-age children and can affect their quality of life and academic performance. The World Health Organization (WHO) reports that approximately 153 million people experience vision impairment due to uncorrected refractive errors, with 70% of blindness in Indonesia caused by this issue. Children with uncorrected refractive errors often struggle to read the blackboard, see learning materials, and experience headaches and eye fatigue. This study aims to determine the prevalence and types of refractive errors in students of SDN 16 and 17 Duri Kepa, West Jakarta.  A quantitative cross-sectional study design was used, with examinations conducted using the Snellen Chart and autorefractometer to measure students' visual acuity.  Of 601 students, 309 (51.4%) had refractive errors. The most common type of refractive error was a combination of myopia and astigmatism (47.6%). The distribution by gender showed that more females (55.8%) had refractive errors than males (50.7%). The highest prevalence was found in 8-year-old children (21.1%) and 2nd-grade students (26.6%). The importance of routine eye examinations in elementary schools to detect refractive errors early and raise awareness about eye health.

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