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INDONESIA
Indonesian Journal of Science and Pharmacy
Published by Pustaka Media Publishing
ISSN : -     EISSN : 30255244     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Indonesian Journal of Science and Pharmacy (IJSP) accepts scientific articles as original research articles, short communication, reviews, and mini-reviews from anyone without any discrimination, as long as they submit articles that meet scientific principles. Indonesian Journal of Science and Pharmacy publishes various scientific articles covering Science and Pharmacy, Pharmaceutical Sciences. The following are the field within the scope of Indonesian Journal of Science and Pharmacy: Chemistry, Biology, Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Pharmaceuticals, Analytical Pharmacy-Medicinal Chemistry, Natural Product Development, Management Pharmacy, Clinical-Community Pharmacy, Microbiology Pharmacy.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 55 Documents
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Association Between Knowledge Level and Pain Self-Medication Behavior Among Residents of Sabungan Nihuta IV Village, Sipahutar District, North Tapanuli Kasan, Harsan Arifin; Lestari, Meliani Dwi; Siburian, Elsa
Indonesian Journal of Science and Pharmacy Vol. 3 No. 3 (2026): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v3i3.155

Abstract

Self-medication is a common practice, particularly in rural areas with limited access to healthcare services. Analgesics are among the most frequently used medications for pain management; however, inappropriate use may lead to drug-related problems due to insufficient knowledge. This study aimed to analyze the relationship between knowledge level and pain self-medication behavior using analgesics among residents of Sabungan Nihuta IV Village, Sipahutar District, North Tapanuli Regency. This research employed a quantitative cross-sectional design with a sample of 78 respondents selected using cluster random sampling. Data were collected through questionnaires and analyzed using the Spearman correlation test. The results showed that most respondents had a good level of knowledge (79%), while the majority demonstrated moderate self-medication behavior (54%). Statistical analysis revealed a significant relationship between knowledge level and self-medication behavior (p = 0.000 < 0.05). In conclusion, knowledge level is significantly associated with self-medication behavior. Strengthening community education is necessary to promote rational, safe, and responsible use of analgesics.
Potential of Instant Temulawak (Curcuma xanthorrhiza Roxb.) as an Immunomodulatory Agent against Viral Infections: A Systematic Narrative Review Firmansah, Moh.; Thaher, M Iman Tarmizi; Palungan, Juliana; Dewa, Sima Asmara; Rahmah, Winda Wahyu Setya; Arta, Alfa Frista; Fauziyah, Ageng Hasna
Indonesian Journal of Science and Pharmacy Vol. 3 No. 3 (2026): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v3i3.160

Abstract

The COVID-19 pandemic has significantly increased public interest in traditional herbal medicines, particularly instant temulawak (Curcuma xanthorrhiza Roxb.), as immune-boosting agents. This systematic narrative review evaluates the immunomodulatory and antiviral potential of temulawak's bioactive compounds, especially curcuminoids, in the context of instant herbal formulations. A comprehensive literature search was conducted across PubMed, Google Scholar, Scopus, and Science Direct using Boolean operators. From 247 initial records, 38 articles met the inclusion criteria. Evidence demonstrates that curcuminoids exhibit broad-spectrum antiviral activity against SARS-CoV-2, influenza, hepatitis B/C, dengue, and HIV through inhibition of viral entry, replication, and modulation of NF-κB, MAPK, and JAK/STAT signaling pathways. Immunomodulatory effects include enhanced macrophage function, T-cell modulation, and cytokine balance regulation. A notable case report showed C. xanthorrhiza consumption led to HBsAg seroconversion in a chronic hepatitis B patient. However, critical gaps persist regarding the specific efficacy of instant formulations, bioavailability challenges of curcumin in processed forms and the absence of rigorous clinical trials on temulawak instan specifically. Future research should prioritize standardized formulations, bioavailability optimization, and clinical validation to bridge the translational gap between in vitro evidence and practical herbal applications.
Association Between Antihypertensive Medication Adherence and Quality of Life in Hypertensive Patients Hutagaol, Sherly H.; Sibagariang, Ayu; Pardosi, Naomi
Indonesian Journal of Science and Pharmacy Vol. 3 No. 3 (2026): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v3i3.161

Abstract

Hypertension is a chronic non-communicable disease known as a “silent killer” that can reduce patients’ quality of life if not properly managed. Medication adherence is a key determinant of therapeutic success and prevention of complications. This study aimed to analyze the relationship between adherence to antihypertensive medication and quality of life among hypertensive patients at Porsea Regional General Hospital. This study used a quantitative observational design with a cross-sectional approach. A total of 57 hypertensive patients were selected using accidental sampling. Medication adherence was measured using the MMAS-8 questionnaire, while quality of life was assessed using WHOQOL. Data were analyzed using the Spearman correlation test. The results showed that 35.1% of respondents had high adherence, while most respondents had moderate quality of life. Statistical analysis indicated that there was no significant relationship between medication adherence and quality of life (Sig. = 0.049; p > 0.05). In conclusion, adherence to antihypertensive medication was significantly associated with quality of life in this population. However, improving adherence remains important to prevent complications and optimize patient outcomes.
Drug Utilization Pattern in Osteoarthritis Patients at Porsea Regional Hospital Togatorop, Baharuddin; Tamba, Rosanto; Pangaribuan, Daniel
Indonesian Journal of Science and Pharmacy Vol. 3 No. 3 (2026): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v3i3.162

Abstract

Osteoarthritis (OA) is a degenerative joint disease that causes chronic pain and functional limitations, particularly in elderly populations. This study aimed to describe the pattern of drug utilization in OA patients at Porsea Regional General Hospital. This descriptive observational study used a retrospective approach based on outpatient and emergency medical records from March to May 2025. A total of 75 patient cases were selected using stratified random sampling. Variables analyzed included patient characteristics, comorbidities, types and classes of OA drugs, concomitant medications, and polypharmacy categories. The results showed that most patients were female (73.34%) and aged ≥60 years (65.53%). The majority had comorbidities (90.67%), with one to three conditions. The most frequently used OA drugs were non-selective NSAIDs, particularly diclofenac sodium (54.67%), followed by COX-2 selective inhibitors (meloxicam, 45.33%), paracetamol (10.67%), and opioid combinations (tramadol-paracetamol, 4.00%). Concomitant medications included vitamins/supplements (90.67%) and gastrointestinal drugs (85.33%). Major polypharmacy was observed in 81.33% of patients. In conclusion, OA patients were predominantly elderly women with high comorbidity and polypharmacy rates, and treatment was mainly dominated by NSAIDs.
The Effect of Family Support and Flash Card Education on Medication Adherence Among Elderly Patients with Type 2 Diabetes Mellitus Fitriani, Anita; Budi, Setia; Agustina, Ani
Indonesian Journal of Science and Pharmacy Vol. 3 No. 3 (2026): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v3i3.166

Abstract

Suboptimal medication adherence remains a major challenge in managing type 2 diabetes mellitus among older adults, particularly in primary healthcare settings with limited long-term monitoring. Limited understanding of medication use and low family involvement are frequently associated with poor adherence behavior. This study aimed to assess changes in medication adherence following the implementation of family support and flash card–based education among elderly patients with type 2 diabetes mellitus. A pre-experimental one-group pretest–posttest design was conducted involving 88 purposively selected participants. Medication adherence was measured using a validated instrument. Data were analyzed using the Wilcoxon signed-rank test to compare pre- and post-intervention scores, Spearman correlation to examine the association between family support and adherence, and multiple linear regression to identify contributing factors. The results showed a significant increase in adherence scores after the intervention (p<0.001). Family support was moderately associated with medication adherence (r=0.462). Furthermore, the combined variables explained 33.0% of the variance in adherence (R²=0.330). These findings suggest that family-oriented visual education may serve as a feasible pharmaceutical care approach to support medication adherence among elderly patients, although further controlled studies are needed to confirm causal relationships.

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