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Jurnal Sains dan Kesehatan
Published by Universitas Mulawarman
ISSN : 23030267     EISSN : 24076082     DOI : 10.25026/jsk
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Jurnal Sains dan Kesehatan menerima naskah karya asli (Artikel Penelitian, Artikel Review, dan Studi Kasus), baik eksperimental maupun teoretis, dalam bidang-bidang berikut: Sains dan Kesehatan (Kedokteran, Farmasi, Kesehatan Masyarakat, Keperawatan, Kebidanan, Gizi, dan lain-lain). Tujuan penerbitan Jurnal Sains dan Kesehatan adalah untuk menyediakan informasi ilmiah tentang perkembangan ilmu dan teknologi di bidang Ilmu Pengetahuan dan Kesehatan.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 750 Documents
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Evaluasi Pelaksanaan Konseling di Apotek Etika Farma Brebes berdasarkan PERMENKES RI Nomor 73 Tahun 2016 Hanari Fajarini; Apriyanti Ludin
Jurnal Sains dan Kesehatan Vol. 2 No. 4 (2020): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v2i4.207

Abstract

ABSTRACT Counseling services in pharmacies is an activity that is essential to prevent medication errors. Counseling services intended to allow patients can use the drug correctly . Only this time the role of Pharmacists in counseling services not running optimally. Formulation of the problem of the research is how the implementation of counseling by Pharmacists in Etika Farma Pharmacy, while the aim to evaluate the implementation of counseling by Pharmacists at Etika Farma Pharmacy. The method used in this study is qualitative research that is intended to provide a clear picture of the problems studied or answered to solve the current problems faced in the current situation. This type of research is an evaluation (evaluation study) is done by assessing a program that is being. These results indicate that the implementation of counseling at the Etika Farma Pharmacy has not gone well. Key words: Counseling Services, Pharmacies, Pharmaceutical Services Standard ABSTRAK Pelayanan konseling di apotek merupakan kegiatan yang sangat penting untuk mencegah terjadinya medication error. Pelayanan konseling ditujukan agar pasien dapat menggunakan obat secara benar. Hanya saja selama ini pelaksanaan pelayanan konseling belum berjalan maksimal. Metode yang digunakan dalam penelitian ini adalah metode penelitian kualitatif yang dimaksudkan untuk memberikan gambaran secara jelas mengenai masalah-masalah yang diteliti atau menjawab untuk memecahkan permasalahan yang sedang dihadapi pada situasi sekarang. Jenis penelitian ini adalah evaluasi (evaluation study) yang dilakukan dengan menilai suatu program yang sedang dilakukan. Hasil penelitian ini menunjukan bahwa kegiatan konseling diberikan hanya kepada pasien penerima resep. Konseling dilaksanakan oleh apoteker, namun ketika apoteker tidak berada di apotek, konseling dilaksanakan oleh tenaga teknis kefarmasian. Kesulitan dalam melakukan konseling adalah pada saat menyampaikan efek samping obat. Penyampaian tentang efek samping obat harus disampaikan dengan bahasa yang tepat, sehingga tidak membuat pasien merasa khawatir dalam mengkonsumsi obat. Dokumentasi konseling belum dilakukan di apotek Etika Farma, hanya ada dokumentasi resep. Kata kunci : Konseling, Apotek, Standar Pelayanan Kefarmasian
Hubungan Kepatuhan dan Kualitas Hidup Pasien HIV/AIDS di Kota Samarinda Dewi Rahmawati; Jaka Fadraersada; Rani Oktavianir
Jurnal Sains dan Kesehatan Vol. 2 No. 4 (2020): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v2i4.209

Abstract

Adherence to taking antiretroviral drugs is very important to prevent HIV replication in the body. Compliance with taking medication can improve the quality of life of HIV/AIDS patients. This study aims to determine the and quality of life HIV/AIDS patients and the relationship between adherence with the quality of life of HIV/AIDS patients in Samarinda City. The method used in this study was observational with prospectively used quantitative descriptive analysis to explain the adherence and quality of life of HIV/AIDS patients while for the relationship of adherence and quality of life of HIV/AIDS patients using non-parametric statistics with the wilcoxon test. The results showed that Compliance in HIV patients in Abdul Wahab Sjahranie Hospital are moderate compliance and in some puskesmas are low compliance. The quality of life of HIV/AIDS patients in Abdul Wahab Sjahranie Hospital are adequate quality of life and in some puskesmas the quality of life varies. The relationship of adherence with the quality of life of HIV/AIDS patients in Abdul Wahab Sjahranie Hospital and several puskesmas has a p ? 0,05 or can indicate no relationship between adherence with quality of life.
Hubungan Status Gizi dan Kepatuhan Diet dengan Kualitas Hidup pada Pasien Penyakit Ginjal Kronis yang Menjalani Hemodialisis Rutin di RSUD Abdul Wahab Sjahranie Samarinda Silvanus Giovanny Bunga Allo; Meiliati Aminyoto; Yuliana Rahmah Retnaningrum
Jurnal Sains dan Kesehatan Vol. 2 No. 4 (2020): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v2i4.210

Abstract

Penyakit ginjal kronis telah menjadi masalah kesehatan dunia yang salah satu penanganannya adalah hemodialisis. Status gizi pada pasien penyakit ginjal kronis yang menjalani hemodialisis adalah hal yang harus diperhatikan, karena pada pasien tersebut sering terjadi malnutrisi dan dapat mempengaruhi kualitas hidupnya. Penelitian ini bertujuan untuk mengetahui hubungan status gizi dengan kualitas hidup pada pasien penyakit ginjal kronis yang menjalani hemodialisis di RSUD Abdul Wahab Sjahranie Samarinda. Penelitian ini merupakan penelitian analitik observasional dengan metode cross sectional. Metode sampling yang digunakan adalah purposive sampling dengan 50 responden. Data status gizi dan kualitas hidup diperoleh dengan menggunakan kuesioner. Hasil penelitian ini menunjukkan 10 % responden memiliki status gizi normal, 56% responden mengalami malnutrisi ringan-sedang, dan 34% mengalami malnutrisi berat. Responden yang memiliki kualitas hidup baik 66% dan responden yang memilki kualitas hidup buruk 34%. Responden dengan malnutrisi cenderung memiliki kualtias hidup buruk, dan terdapat hubungan bermakna antara status gizi dengan kualitas hidup (p = 0,000).
Gambaran Status Konsumsi Air Minum Pada Pasien Batu Saluran Kemih Syifa Fitria Anggraeny; Boyke Soebhali; Sulistiawati Sulistiawati; Poppy Desra S Nasution; Endang Sawitri
Jurnal Sains dan Kesehatan Vol. 3 No. 1 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i1.211

Abstract

Penyakit batu saluran kemih (BSK) adalah pembentukan batu yang disebabkan oleh pengendapan kristal yang dapat terjadi di ginjal, ureter, buli, dan uretra. Penyakit BSK merupakan penyakit ketiga terbanyak di bidang urologi setelah infeksi saluran kemih dan pembesaran prostat benigna. Salah satu faktor risiko penyakit BSK adalah asupan air minum yang kurang. Asupan air minum yang kurang menyebabkan volume urine yang tidak cukup untuk membuang zat sisa metabolisme dan garam yang berlebihan, serta menyebabkan supersaturasi urine dan retensi endapan zat terlarut dalam urine yang memudahkan terbentuknya BSK. Penelitian ini merupakan penelitian deskriptif observasional dengan pendekatan cross sectional serta menggunakan metode purposive sampling yang bertujuan untuk mengetahui gambaran status konsumsi air minum pada pasien batu saluran kemih di RSUD Abdul Wahab Sjahranie Samarinda. Data yang diperoleh berasal dari hasil wawancara pasien menggunakan kuesioner BEVQ-15 dan data rekam medik RSUD Abdul Wahab Sjahranie Samarinda. Jumlah sampel yang diperoleh sebesar 55 pasien yang telah didiagnosis BSK. Hasil menunjukkan bahwa terdapat 56,4% responden dengan status konsumsi air minum yang masih kurang dengan rata-rata konsumsi air minum sebanyak 2343,5 ml/hari. Jumlah ini masih kurang dari anjuran minum European Association of Urology, yaitu 2500 ml/hari. Kesimpulan yang dapat ditarik dari hasil penelitian adalah status konsumsi air minum pasien BSK sebagian besar berada pada kategori kurang. Kata Kunci: Konsumsi Air Minum, Batu Saluran Kemih
Peranan Sel Limfosit Dalam Imunulogi: Artikel Review Flora Ramona Prakoeswa
Jurnal Sains dan Kesehatan Vol. 2 No. 4 (2020): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v2i4.212

Abstract

Lymphocytes are found in blood and lymph. Besides Natural killer (NK) cells, T cells and B cells are the different forms of lymphocytes. Each of these cells plays fundamental role in the body adaptive immune response. B lymphocytes are central players in the immune response; canonically, they have been recognized as precursors of antibody-producing cells: plasma cells. Recent findings have shown that the role of B lymphocytes goes far beyond the production of antibodies. There are different subtypes of B lymphocytes with different participations in innate and adaptive responses that include the recognition of the antigen, its processing, and its presentation to T lymphocytes, as well as the production of cytokines that impact and modulate the response toward the pathogen. Traditionally, it has been considered that B lymphocytes do not have phagocytic abilities that allow them to internalize, to process, or even to be infected by bacterial pathogens. The new information has shown that B lymphocytes can be readily infected by bacterial pathogens and respond to those infections. T lymphocytes play a role in cytotoxic immune responses. They belong to the adaptive immune system and perform a wide array of functions in immune regulation, inflammation and protective immune responses. In recent years, it has been shown that T cells are involved essentially across the entire spectrum of tissue physiology and pathology, not just in reactions or diseases considered to be bonafide immunological, but also, to cite just some examples, in metabolism, in tissue repair, in dysbiosis, and in pregnancy. Basic research on T cells has also sown the seeds that spawned the new era of immunotherapy that is engaging numerous researchers in finding a cure for cancer. The review of this article aims to further understand the latest findings regarding the formation and work mechanism of lymphocytes, especially on adaptive immunity. It summarizes the various forms of lymphocytes and their immunomodulatory roles in health and diseases.
Hubungan Kejadian Skor Apgar Kurang dari 7 dengan Faktor Risiko Ibu dan Persalinan di RSUD Abdul Wahab Sjahranie Samarinda Tahun 2018-2019: Relationship between Incidence of Apgar Score Less than 7 with Risk Factors for Mother and Childbirth at Abdul Wahab Sjahranie Hospital, Samarinda in 2018-2019 Caecilia Anggi Raharjo; Novia Fransiska Ngo; Annisa Muhyi
Jurnal Sains dan Kesehatan Vol. 3 No. 2 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i2.213

Abstract

Asfiksia neonatorum adalah suatu kondisi dimana terdapat gangguan pertukaran gas karbondioksida dan oksigen yang menyebabkan terjadinya hipoksemia dan hiperkarbia pada janin yang berujung pada asidosis yang biasanya dapat dilihat dari skor apgar yang rendah. Asfiksia neonatorum menempati posisi kedua tertinggi penyebab kematian neonatus dengan angka 4 juta kematian setiap tahunnya. Penelitian ini bertujuan untuk mengetahui hubungan antara kejadian skor apgar kurang dari 7 dengan faktor risiko ibu yang terdiri dari usia ibu, paritas, anemia pada saat hamil, dan faktor risiko persalinan yang terdiri dari partus lama. Desain penelitian yang digunakan adalah kasus kontrol dengan sampel penelitian masing-masing sebanyak 46 untuk kelompok kasus dan kontrol. Analisis dilakukan dengan uji chi-square. Hasil penelitian menunjukan bahwa terdapat hubungan antara kejadian skor apgar kurang dari 7 dengan partus lama, serta tidak terdapat hubungan antara kejadian skor apgar kurang dari 7 dengan Usia Ibu, paritas dan Anemia.
Kehamilan Multipel, Riwayat Preeklamsia, dan Hipertensi Kronik Berhubungan dengan Kejadian Preeklamsia di RSUD Abdul Wahab Sjahranie Samarinda Tahun 2017-2019 Miranda Shaqilla Antareztha; Novia Fransiska Ngo; Nurul Hasanah
Jurnal Sains dan Kesehatan Vol. 3 No. 1 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i1.214

Abstract

Hypertension disorders in pregnancy account for about 14% of all maternal deaths worldwide. Preeclampsia is one of the main causes of maternal and perinatal morbidity and mortality from all disorders of hypertension in pregnancy. Preeclampsia is hypertension that arises after 20 weeks of pregnancy accompanied by proteinuria or other organ system disorders. Risk factors that cause preeclampsia include multiple pregnancy, history of preeclampsia, and chronic hypertension. The purpose of this study was to find the relationship between risk factors and the incidence of preeclampsia in Abdul Wahab Sjahranie Regional Hospital Samarinda. The design in this study used a case-control study with observational analytic methods. Data was taken from medical records of patients who gave birth at Abdul Wahab Sjahranie Hospital Samarinda in the January 2017-December 2019 period and found 48 cases and 48 controls. Bivariate analysis was performed using the chi-square test and fisher test if the expected countless than 5. The analysis results obtained a significant relationship between multiple pregnancies (p = 0.001), history of preeclampsia (0.012), and chronic hypertension (p = 0.007) with the incidence of preeclampsia in Abdul Wahab Sjahranie Regional Hospital Samarinda. Gangguan hipertensi pada kehamilan menyumbang sekitar 14% dari seluruh kematian ibu di seluruh dunia. Preeklamsia adalah salah satu penyebab utama morbiditas dan mortalitas pada maternal dan perinatal dari seluruh gangguan hipertensi pada kehamilan. Preeklamsia merupakan hipertensi yang timbul setelah 20 minggu kehamilan disertai dengan proteinuria atau gangguan sistem organ lainnya. Faktor-faktor risiko yang menjadi penyebab terjadinya preeklamsia diantaranya adalah kehamilan multipel, riwayat preeklamsia, dan hipertensi kronik. Tujuan dari penelitian ini adalah mengetahui hubungan antara faktor risiko dengan kejadian preeklamsia di RSUD Abdul Wahab Sjahranie Samarinda. Desain dalam penelitian ini menggunakan studi kasus kontrol dengan metode analitik observasional. Data diambil dari rekam medik pasien yang melahirkan di RSUD Abdul Wahab Sjahranie Samarinda periode Januari 2017-Desember 2019 dan didapatkan 48 kasus dan 48 kontrol. Analisis bivariat dilakukan menggunakan uji chi-square dan uji fisher’s exact jika nilai harapan kurang dari 5. Hasil analisis diperoleh adanya hubungan bermakna antara kehamilan multipel (p=0,001), riwayat preeklamsia (0,012), dan hipertensi kronik (p=0,007) dengan kejadian preeklamsia.
Analisis Kadar Air dan Kadar Protein pada Surimi Ikan Patin (Pangasius, sp) dengan Variasi Pencucian dan Penambahan Tepung Sagu Rosa Devitria; Harni Sepriyani
Jurnal Sains dan Kesehatan Vol. 3 No. 1 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i1.215

Abstract

Patin Fish (Pangasius, SP), is one type of freshwater fish found in rivers in Riau Province. Patin fish is a source of high quality food, but it is a highly perishable food. Therefore, to overcome this need a way of preservation and processing that can maintain durability and not reduce the nutritional value that is by making surimi. In this research, the basic ingredients of patin fish are made with sago flour. Sago flour has different physical properties from tapioka flour and wheat flour so that it will increase the ability to from in surimi. Surimi is made with washing variations and added sago four. The results of this research were obtained from testing the chemical characteristics of surimi which were made with washing variations and obtained sago flour. The lowest and highest water conten of surimi is 52.1832% and 75.7656%. The lowest and highest protein content of surimi is 8.6631 % and 17.5487%.
Hubungan Kadar Troponin T dengan Lama Perawatan dan Mortalitas Selama Perawatan pada Pasien Infark Miokard Akut di RSUD Abdul Wahab Sjahranie Samarinda Sherin Nadia Khalista; Agustina Rahayu Magdaleni; Diah Purwandini Asmoro
Jurnal Sains dan Kesehatan Vol. 2 No. 4 (2020): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

In the setting of acute myocardial infarction (AMI), an increased in cardiac biomarker levels is a parameter supporting the diagnosis of AMI. There are several types of cardiac biomarkers, including CK-MB, troponin T, troponin I, LDH, and myoglobin. Troponin is one of the recommended cardiac biomarker owing to its high specificity. Besides indicating the occurrence of AMI, troponin T is also known to have an association with ischemic duration, degree of ischemia, extent of infarction, complications, and even mortality among AMI patients. These parameters are thought to be the factors that influence the length of stay and in-hospital mortality in AMI patients. Therefore, the author was interested to determine the relationship between troponin T levels with treatment duration and in-hospital mortality in AMI patients. This analytical study was conducted using cross-sectional approach and secondary data. The study samples are AMI patients treated at Abdul Wahab Sjahranie Hospital in Samarinda between January 1, 2018 - December 31, 2018 who met the inclusion and exclusion criteria. In total, this study involved 86 people. The results show that the average troponin T levels in AMI patients is 1159.93 pg/ml, the average length of stay is 5.11 days, and the percentage of mortality during treatment is 10.5%. Bivariate analysis shows that troponin T does not have a significant relationship with length of stay (p = 0.422) and in-hospital mortality (p = 1,000). Thus, it can be concluded that troponin T levels are not associated with length of stay and in-hospital mortality in AMI patients. Keywords : AMI, Troponin T levels, Length of Stay, In-Hospital Mortality
Efektivitas Antibakteri Senyawa Kurkumin terhadap Foodborne Bacteria: Tinjauan Curcuma longa untuk Mengatasi Resistensi Antibiotik Anak Agung Ayu Dewi Sekarini; Ita Krissanti; Mas Rizky A. A. Syamsunarno
Jurnal Sains dan Kesehatan Vol. 2 No. 4 (2020): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Antibiotic resistance has negatively impacted the food safety with increasing number of resistant foodborne bacteria, especially foods from farm animals. Turmeric or Curcuma longa has curcumin as its main active component, which is known to have wide range biological activities and low toxicity. Curcumin shows better antibacterial effectiveness than C. longa extract in vitro and in vivo studies, so that has big potential as an alternative antibacterial because of its inexpensiveness, easy to find, and safe to use. However, curcumin is hydrophobic, that makes it hard to dissolve in the body, thus it needs other formulation to enhance its bioavailability. This review discusses the antibacterial activity of curcumin against foodborne bacteria including various formulations, mechanisms, and the toxicity of curcumin.

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