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Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Published by SEKOLAH TINGGI ILMU KESEHATAN SAMARINDA
ISSN : 2443115X     EISSN : 24771821     DOI : https://doi.org/10.51352/jim
Core Subject : Health, Science,
Chemistry Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Jurnal Ilmiah Manuntung is a journal on pharmaceutical and health sciences published by Sekolah Tinggi Ilmu Kesehatan Samarinda which includes the study of pharmaceutical sciences, medicine, synthetic organic chemistry, organic chemistry of natural materials, biochemistry, analytical chemistry, physical chemistry, biology, microbiology, tissue culture, botany and animals related to pharmaceutical products, nursing, midwifery, health analysts, nutrition and public health.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 326 Documents
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ANALISIS RISIKO REAKSI OBAT YANG TIDAK DIKEHENDAKI PADA PASIEN HIPERTENSI GERIATRI DI RSUD ARIFIN ACHMAD PROVINSI RIAU Septi Muharni; Erniza Pratiwi; Yuwanda Iswari
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i1.224

Abstract

Adverse Drug Reaction (ADR) is every adverse event related to the use of a drug in humans. Geriatrics have a 7 times greater risk of developing ADR. Hypertension is the most common disease suffered by geriatric patients. The purpose of this study was to analyze the risk of ADR occurrence in geriatric hypertension patients and also to analyze the relationship of demographic data with the incidence of ADR. This study was carried out in an observational manner which was descriptive analytic with a cross sectional approach in 88 medical record samples of geriatric hypertension patients in inpatient installations using gerontoNET scores. Based on the ADR risk variable according to the gerontoNET score, there was 1 patient with ≥4 comorbid, 45 patients had heart failure, 5 patients had liver disorders, 19 patients received 6-7 drugs and 37 patients received ≥8 drugs, no patients with ADR history, and 28 patients developed kidney problems. From the results of this study, there are 37 patients who have a high risk of ADR events which are marked by gerontoNET score ≥4. Based on the correlation analysis of gender and age range on ADR risk obtained a weak relationship and no significant correlation (r = 0.116, p = 0.116; r = 0.017, p = 0.847), so that gender and age in geriatric hypertension patients are not related to the risk of ADR.
ANALISIS PENGARUH KUALITAS PELAYANAN TERHADAP KEPUASAN PASIEN RAWAT JALAN DI INSTALASI FARMASI RUMAH SAKIT X KOTA SURAKARTA Habel Roy Sulo; Elina Hartono; R. A. Oetari
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i1.226

Abstract

The development and improvement of pharmacy service has become consumer concern, since this quality of service will affect on consumer satisfaction. The study aimed at assessing the level of outpatient satisfaction at Department of Pharmacy X Hospital In Surakarta City. This study was a survey research, which was conducted using questionnaire by direct interview. A total of 323 respondent were recruited conveniently in the study. The obtained data was then analyzed using Gap analysis to assess the differences in level of quality services between customer perceptions and customer expectations. The study investigates the five dimensions of service quality and identifies the gap between the perception and expectation. The data was analyzed by using SPPS for windows. In general, the result shows that service quality was lower than the expectations of the patients in the studied hospital. The study finding indicated that gap or differences exist on various dimensions between perception and expectation in level quality services. The highest service quality gap was given to Responsiveness followed by Reliability, Empathy, Tangibles and Assurance with the value of - 0,129; - 0,125; - 0,115; - 0,114; and - 0,108 respectively. Patient satisfactions was influenced by health service quality, with the assurance and responsiveness dimensions as the greatest influence on patient satisfaction.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN KEDONDONG HUTAN (Spondias pinnata (L.F.) Kurz.) DENGAN BERBAGAI METODE UJI Suhaimi Azizah; Nursamsiar Nursamsiar; Syamsu Nur
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i1.227

Abstract

The leaf of kedondong hutan (Spondias pinnata (L.F.) Kurz.) Contain of flavonoid compound, which capable as antioxidants that function for preventing free radicals. The purpose of this study was to determine the antioxidant activity profile of ethanol extract of kedondong hutan leaf with DPPH, ABTS radical and iron reduction methode (FRAP). This study used experimental research with stages of sample collection, plant determination, simplicia preparation, maceration with 70% ethanol, phytochemical screening and antioxidant activity assay with UV-Vis spectrophotometry. The results obtained from the ethanol extract of kedondong hutan leaves had antioxidant activity on DPPH and ABTS with IC50 of 32.83 ppm and 45.84 ppm respectively. In FRAP method kedondong hutan leaves had antioxidant activity which is equivalent to quarcetin of 2936.7 µmol QR /g sample. Ethanol extract of kedondong hutan leaves has very strong antioxidant power against DPPH, ABTS radical and iron reduction.
ANALISIS PERSPEKTIF PEMBELAJARAN DAN PERTUMBUHAN DALAM MENGUKUR KINERJA INSTALASI FARMASI RSUD A.M. PARIKESIT TENGGARONG KUTAI KARTANEGARA KALIMANTAN TIMUR DENGAN PENDEKATAN Balanced Scorecard: Analisis Perspektif Pembelajaran Dan Pertumbuhan Dalam Mengukur Kinerja Instalasi Farmasi RSUD A.M. Parikesit Tenggarong Kutai Kartanegara Kalimantan Timur Dengan Pendekatan Balanced Scorecard Tria Saputra Saharuddin; Satibi Satibi; Tri Murti Andayani
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i1.234

Abstract

Pharmacy Department A.M. Parikesit Regional General Hospital always working to improve the quality of service, analyses is need to find the performance in Pharmacy Department A.M. Parikesit Regional Public Hospital. The concept of the balanced scorecard is a performance evaluation tool that is comprehensive, coherent and relevant to be applied in hospitals for improving the performance of every aspect of total. The study to evaluate the performance Pharmacy Department A.M. Parikesit Regional General Hospital through learning and growth perspective. This research used non experimental case study arrangement research the explorative descriptive approach. Data collection was retrospective and prospectively in the form of quantitive data. Qualitative data was obtained by questionnaires, depth interview with the head of Pharmacy Departmen A.M. Parikesit. The quantitative data obtained through direct observation and personnel file. The results of research with the used balanced scorecard at a performance perspective learning and growth shown that: a. human capital: Good category productivity of employess, the level of employee productivity is 86.73%, the percentage of employees who received training in 2013, 2014 and from January to July 2015 is respectively for 15.38%, 32.25% and 97, 72%, the average value of the high category in morale, job satisfaction, knowledge, empskill and talent; b. information capital showed the average category of high on the aspect of information technology, a database and network, but need the information management system updates for support the management and drug reporting and need to improve communication with the customer network.; c. organization capital showed the value of the average category of high on the aspect of cultural organization ,leadership and alignment.
OPTIMASI CAMPURAN PATI JAGUNG DAN AVICEL PH 101 SEBAGAI BAHAN PENGHANCUR PADA TABLET EKSTRAK BUAH PARE (Momordica charantia L.) SECARA GRANULASI BASAH Dwi Saryanti; Heny Ismawati; Iwan Setiawan
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i1.239

Abstract

Bitter melon fruit (Momordica charantia L.) can be used as traditionally to reduce blood sugar levels. Avicel PH 101 and corn starch are efficacious as fillers, disintegration excipient and binders. The combination of Avicel PH 101 with corn starch is expected to be able accelerate the tablet disintegration time of tablet. This research was aimed to get the optimum formula tablets of bitter melon extract tablets using combination of corn starch and avicel PH 101. Bitter melon extract was formulated in tablet with wet granulation method. Bitter melon extract was obtained by maceration with ethanol 70% as solvent. Tablet formula based on the Simplex Lattice Desaign method uses Design Expert software version 11 with parameters that are used weight uniformity, hardness, friability and disintegration time. The results obtained from the simplex lattice design compared with the results of testing using the SPSS 18 program using the One Sample T-Test with a confidence level of 95%. The result of this research indicate bitter melon extract was made by tablets with wet granulation method with a combination of Avicel PH 101and corn starch, a formula with a ratio of 51% : 49% selected as the optimum formula with weight uniformity, hardness, friability and disintegration time meeting the requirements. Keywords : bitter melon extract, tablets, corn starch, avicel PH 101, simplex lattice design
FORMULASI DAN EVALUASI LIP BALM LIOFILISAT BUAH TOMAT (SOLANUM LYCOPERSICUM L.) SEBAGAI PELEMBAB BIBIR Nurul Arfiyanti Yusuf; Besse Hardianti; Indah Ayu Lestari; Amriani Sapra
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i1.244

Abstract

The research on formulation and evaluation of lypholized tomato (Solanum lycopersicum L) as lip balm has been conducted. The objective of this research was to investigate the physical stability of lip balm formula from lypholized tomato that could enhance the lips’ humidity. The formulation of lip balm was made into three concentration i.e 1%, 3%, and 5%. The physical stability evaluations that were performed before and after stress condition. Which is included organoleptic, homogeneity, and melting point test. The stable formula was then evaluated as skin moisture enhancer using skin analyzer. The results of this research showed that all three formula was physically stable. On the third formula (lypholized concentration of 5%) had the highest percentation of moisture enhancement with the significant difference among the three formulas.
EFEKTIVITAS EKSTRAK KULIT JERUK NIPIS (Citrus Aurantifolia) TERHADAP DAYA PROTEKSI NYAMUK Marjan Wahyuni; Ricky Adiwanto
Jurnal Ilmiah Manuntung Vol 5 No 2 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i2.247

Abstract

Dengue Hemorrhagic Fever (DHF) is an acute fever caused by the dengue virus that enters human blood circulation through mosquito bites from the genus Aedes. Until now there is no cure for dengue disease, so people often panic if contracting the dengue virus. Various methods are used to prevent transmission of the dengue virus, one of which is the use of plants as a natural mosquito repellent. Continuous use of chemicals, besides adversely affecting health, will also make mosquitoes resistant. Therefore, it is necessary to use various alternative anti-mosquito drugs from plant species, one of which is lime. Lime skin contains one of the mosquito repellent substances so that it is possible for the lime peel to be effective as a mosquito repellent. This study aims to determine whether the extract from lime peel is effective as a mosquito protection power. The research method used was Quasi Experiment with 4 treatment activities and 3 replications, namely A (0%), B (15%), C (30%) D (45%). The object in this study was the aedes aegipty mosquito. Reppelent is considered effective if the protection power is ≥ 90%. The results showed that lime peel extract at a concentration of 15%, had a protective ability of 60%. At a concentration of 30% lime peel extract has a protection power of 90%. The protection of lime peel extract is very effective at a concentration of 45%, because it has a protective ability of 98%. With a concentration of 98% lime peel extract can be said as a mosquito repellent. The greater the concentration of orange peel extract, the greater the protection power obtained.
OPTIMASI HYDROXYPROPYL METHYLCELLULOSE DAN CHITOSAN PADA TABLET FLOATING-MUCOADHESIVE SIMETIDIN DENGAN METODE DESAIN FAKTORIAL Mohammad Zulfikhar A.; Dwi Nurahmanto; Lusia Oktora R.K.S.
Jurnal Ilmiah Manuntung Vol 5 No 2 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i2.256

Abstract

Cimetidine is an H2 receptor antagonist which can be used to reduce acid secretion in the stomach by inhibiting selective binding of histamine to H2 receptors so that it can reduce the concentration of cyclic-adenosine monophosphate (c-AMP) which plays a role in the proton pump mechanism. The combination of floating and mucoadhesive systems is used to increase drug retention in the stomach so that it can reduce the drug interval and increase bioavailability of the drug. The purpose of this study was to make floating-mucoadhesive cimetidine tablets using Hydroxypropyl Methylcellulose (HPMC) as a floating polymer and chitosan as a mucoadhesive polymer. Tablets are expected to have the ability to maintain the dosage form in the stomach for approximately 12 hours. The evaluations carried out included the flow characteristics and the angle repose of the powder mixture, tablet weight uniformity, tablet hardness, tablet friability, floating lag time, floating duration time and tablet mucoadhesive strength. The responses observed were the ability to float and the mucoadhesive strength of tablets. The tablet release test (dissolution) for the optimum formula was performed to determine the character of tablet release. The optimum amount for HPMC is 146,686 mg and chitosan are 50 mg. The combination of polymers with this amount produces a floating lag time of 43,458 seconds, floating duration time >12 hours and the strength of mucoadhesive is 100 grams. The release of the optimum formula in the 720th minute is about 73,180% following the Higuchi release model with dissolution efficiency (DE720) about 67,855%.
PENGARUH VARIASI KONDISI FERMENTASI TERHADAP PRODUKSI METABOLIT ANTIBAKTERI EKSTRAK ISOLAT I5 FUNGI ENDOFIT Anredera cordifolia (Ten.) Steenis Ismail Ismail; Megawati Megawati; Alimuddin Ali; Fuji Asmiati Ningsih
Jurnal Ilmiah Manuntung Vol 5 No 2 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i2.260

Abstract

Endophytic fungi are one of the microorganisms that live in plants and symbiotic with their host plant produce secondary metabolites. This study aims to determine the optimum growth profile of endophytic fungus isolated from the leaf of Anredera cordifolia (Ten.) Steenis namely isolate I5 as antibacterial. The fungus growth profile optimization analyzed by a correlation between fermentation time and mycelium weight, which collected every 24 hours for 15 days. The media were varied at pH conditions of 4, 7, and 8 in each PDYB medium (glucose and fructose substrates). The results showed that isolate I5 grew optimally on the 13th day on the PDYB medium pH 8. Ethyl acetate extract 5% of isolate I5 could inhibit bacteria growth with the largest inhibition zone diameter against Staphylococcus aureus of 9.96 mm (± 0.60) and Escherichia coli of 9.03 mm (± 0.46).
EVALUASI PENGGUNAAN ANTIBIOTIK PROFILAKSIS PADA PASIEN BEDAH SESAR (SECTIO CAESAREA) DI RSUD ULIN BANJARMASIN TAHUN 2017 Saftia Aryzki; Hidayatun Nisa; Dian Yunita Gamaliana
Jurnal Ilmiah Manuntung Vol 5 No 2 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i2.263

Abstract

Cesarean section (Sectio Caesarea) is an attempt to remove the fetus through surgery on the abdominal wall and uterus. The use of inappropriate prophylactic antibiotics will lead to infection and resistance. The purpose of this study was to determine prophylactic antibiotic use, in cesarean section patients, to know prophylactic antibiotic use in cesarean section patients in accordance with antibiotic use guidelines (PPAB) Ulin Hospital in 2017, to know prophylactic antibiotic use in cesarean section patients in accordance with Permenkes RI Number 2406 / PER / XII / 2011. This research is a non-experimental type of descriptive study retrospectively by taking medical record data of cesarean section patients at Ulin Banjarmasin Hospital in 2017 with saturated sampling method, obtained a population of 99 medical records of cesarean section with a total sample of 99 medical records. The use of prophylactic antibiotics in Ulin Banjarmasin Public Hospital is a class of third generation cephalosporins namely ceftriaxone and cefotaxime with doses of 1-2 grams / day and duration of 3-5 days. Comparison of the percentage of prophylactic antibiotic use with the guidelines for drug use in Ulin Hospital in Banjarmasin in 2017 is the name and class of 100% is appropriate and 0% is not appropriate, the dose is 100% appropriate and 0% is not appropriate, the duration of administration is 69.70% is appropriate and 30.30% is not corresponding. Comparison of the percentage of prophylactic antibiotic use with Permenkes RI Number 2406 / PER / XII / 2011 is the name and class of 0% is appropriate and 100% is not appropriate, the dose is 0% is appropriate and 100% is not appropriate, the duration of giving 0% is appropriate and 100 % it is not in accordance with.

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