cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Erma Sulistyaningsih
Contact Email
sulistyaningsih.fk@unej.ac.id
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kab. jember,
Jawa timur
INDONESIA
e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
Health Professions Library & Information Science
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
Arjuna Subject : -
Articles 621 Documents
 37   38   39   40   41 
Pengaruh Lama Pemberian Distres Kronis terhadap Aktivitas Sel Osteoklas pada Tulang Alveolar Tikus Sprague-Dawley (The Effect of Chronic Distress Duration to Osteoclast Cells Activity in Alveolar Bone of Sprague-Dawley Rats) Maria Devitha; Didin Erma Indahyani; Happy Harmono
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Excessive and prolonged distress (chronic) can cause damage to periodontal tissues, specifically alveolar bone resorption. Alveolar bone resorption is caused by osteoclast cells activity. The purpose of the research is to determine effect of chronic distress duration to osteoclast cells activity in alveolar bone of male Sprague-Dawley rats attain the age of 3-4 months. The rats were given an electric shock stressor (Electrical Foot Shock) as distress chronic for 7, 14, and 28 days. Stressors were given for 30 minutes at 9 a.m every day during the treatment period. The amount of electrical current is 2-8 mA, 48 V voltages and 0.5 Hz frequency. Osteoclasts activity were observed histologically with 400x magnification using osteoclast Bone Interface (OBI) Index by dividing the length of howship's lacunae with osteoclasts. Result showed signifficant difference at 0.00 (p<0.05) beetwen the variable.Activity of osteoclasts in alveolar bone of Sprague-Dawley rats which were exposed to the stressor is increased when compared to the group that were not exposed to electrical shock stressor, but at day 14 decreased when compared to the other treatment groups. Keyword : chronic distress, osteoclast activity, alveolar bone
Uji Aktivitas Protein Larut Air Umbi Porang (Amorphophallus muelleri Blume) terhadap Escherichia coli dan Staphylococcus aureus Putu Gita Maya Widyaswari Mahayasih; Tri Handoyo; Mochammad Amrun Hidayat
Pustaka Kesehatan Vol 2 No 2 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The objective of this study was to determine antibacterial activity of water soluble protein of Porang (Amorphalus muelleri Blume) tuber. The water soluble protein extract was tested against both Eschericia coli and Staphylococcus aureus using filter paper disk method. The inhibition zone of bacterial growth was calculated for both of bacterial cultures. It was found that water soluble protein exhibited antibacterial activity at linear range 0.3-1.9 μg and 0.1-1.9 μg for E. coli and S. aureus respectively, sugesting that S. aureuswas more susceptible than E. coli to this protein. From the electrophoretic profile using 12.5% sodium dodecyl sulfate (SDS) and comassie blue staining (CBS), two protein bands were observed with molecular weight 17 and 19 kDa respectively. The water soluble protein were further evaluated using periodic acid staining (PAS). Pink band with molecular weight 250 kDa and > 250 kDa was found in PAS profile, sugesting the availability of carbohydrate molecule in water soluble protein extract of porang tubers.
Daya Hambat Ekstrak Buah Delima Merah (Punica granatum Linn) terhadap Pertumbuhan Staphylococcus aureus (The Inhibition of Red Pomegranate Fruit Extract (Punica granatum Linn) on The Growth of Staphylococcus aureus) Erlita Prestiandari; Sri Hernawati; Leni Rohma Dewi
Pustaka Kesehatan Vol 6 No 1 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i1.7157

Abstract

Background: Staphylococcus aureus is the most common microorganism in angular cheilitis. Angular cheilitis is inflammation in one corner of the mouth or both corners of the mouth may extend involving the lips commisura and surrounding skin. The prevalence of angular cheilitis is 0.2-15.1% in children and 0.7-3.8% in adults. One of alternative treatment by using herbal plants, namely red pomegranate. Red pomegranate contains flavonoids, tannins, and alkaloids as antibacterial. Objective: to determine the inhibition of red pomegranate extract on growth of Staphylococcus aureus. Methods: disk diffusion method with 6 samples in each study group. The study group consisted of 4 treatment groups (25%, 50%, 75% and 100% red pomegranate extract), positive control group (fusidic acid), and negative control group (sterile aquades). Data were analyzed using One Way Anova test and LSD (Least Significant Difference) test. Results and conclusions: red pomegranate extract has the ability to inhibit the growth of Staphylococcus aureus. The concentration of red pomegranate extract has the greatest inhibitory effect on S. aureus growth, that is 75% and 100%. Keyword: Antibacterial activity, red pomegranate fruit extract, Staphylococcus aureus, disk diffusion method
Deteksi Gelatin Babi pada Sampel Permen Lunak Jelly Menggunakan Metode Fourier Transform Infra Red (FTIR) dan Kemometrik (Detection of Porcine Gelatin in Jelly Soft Candy Sample Using Fourier Transform Infra Red and Chemometrics) Annisa Rahmawati; Bambang Kuswandi; Yuni Retnaningtyas
Pustaka Kesehatan Vol 3 No 2 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Gelatin is widely used in some food products as gelling agent, including jelly soft candy. Most of commercial gelatin is derived from pork skin. Islam prohibits their followers to consume any food products containing pig derivates, including porcine gelatin. Therefore, it is necessary to develop some rapid and reliable methods for detection of porcine gelatin in jelly soft candy. FTIR method combined with chemometrics were chosen because it is rapid, easy and reliable. The purpose of this study was to classify of porcine gelatin in jelly soft candy using FTIR method combined with multivariate statistical methods (chemometrics). The classification method of chemometrics used to test porcine gelatin in commercial product of jelly soft candy was succesful and also in a good assessment with Xematest Pork. Keywords: bovine gelatin, jelly soft candy, porcine gelatin, FTIR, chemometrics.
Uji Aktivitas Fraksi N-Heksana Ekstrak Metanol Bangle (Zingiber cassumunar Roxb.) sebagai Terapi Komplementer Malaria secara In Vivo (The Activity Test of N-Hexane Fraction of Bangle (Zingiber cassumunar Roxb.) Methanolic Extract as Complementary Thera Sarah Andriani; Bagus Hermansyah; Sugiyanta Sugiyanta
Pustaka Kesehatan Vol 5 No 2 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Malaria is one of endemic disease in Indonesia that caused many deaths. Immune system plays important rules in preventing malaria severity. Bangle has been proven as an immunostimulant and could reduce parasitaemia in malaria infection. This study aimed to determine the activity of n-hexane fraction of bangle methanolic extract as complementary therapy of malaria. This study used 28 mice, divided into one positive control group, one negative control group, and five treatment groups. Bangle stimulation before induction was given to five treatment groups with dose: 0,005625mg/grbw, 0,01125mg/grbw, 0,0225mg/grbw, 0,045mg/grbw, and 0,09mg/grbw for 14 days. Plasmodium berghei induction was given to all groups, and then treatment groups were given ACT and bangle fraction, and positive control group was given ACT without fraction for three days. Parasitaemia was observed everyday, then plasmodium growth inhibition percentation was counted. Bangle fraction stimulation gave lower parasitaemia at the begining and Pearson correlation test showed strong positive correlation between dose of bangle fraction and plasmodium growth inhibition percentation (p<0,01). We can conclude that n-hexane fraction of bangle methanolic extract was active as complementary therapy of malaria (IC50=0,013 mg/grbb). Keywords: malaria, bangle, n-hexane, complementary therapy
Pengaruh Posisi Kerja terhadap Kejadian Low Back Pain pada Pekerja di Kampung Sepatu Kelurahan Miji-Prajurit Kulon-Mojokerto Khulaida Fatila Hayati; Irawan Fajar Kusuma; Muhammad Hasan
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Low Back Pain merupakan gejala utama yang dilaporkan kepada praktisi kesehatan berkaitan dengan menurunnya produktivitas kerja. Posisi kerja yang ergonomi menjadi faktor penentu terjadinya Low Back Pain. Penelitian ini bertujuan mengetahui adanya pengaruh posisi kerja terhadap kejadian Low Back Pain. Sebanyak 60 responden dibagi menjadi 2 kelompok kerja: berdiri dan duduk. Indeks nyeri diukur dengan Visual Analog Scale (VAS) diikuti dengan Pain Assessment Scale. Data dianalisis dengan Chi Square Test dan didapatkan nilai 0,037. Nilai X2 hitung pada posisi kerja duduk lebih tinggi yaitu 14,267  dibandingkan dengan posisi kerja berdiri yaitu 13,467. Kedua posisi kerja baik berdiri maupun duduk sama-sama mempunyai pengaruh yang signifikan terhadap kejadian Low Back Pain. Namun posisi kerja duduk lebih tinggi pengaruhnya dibanding dengan posisi kerja berdiri. Berdasarkan data hasil penelitian menunjukkan bahwa posisi kerja memang memiliki pengaruh terhadap kejadian Low Back Pain. Kata kunci: posisi kerja, low back pain, kampung sepatu, ergonomi
Efek Angiogenesis Beraprost terhadap Gambaran Histopatologi Jantung Tikus Galur Wistar Hipertensi (Angiogenesis Effect of Beraprost on the Cardiac Histopathology of Hypertensive Wistar Rat) Cynthia Damayanti; Suryono Suryono; Arief Suseno
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hypertension is a state where there is an increase of blood pressure above normal threshold,120/80 mmHg. The phatophysiology of hypertension involves the changes of vascular structure. Therefore, the beraprost drug was created. It is a vasodilator and antitrombolytic which is able to induce angiogenesis. The study aimed to investigate the effect of Beraprost on angiogenesis as a hypertension therapy agent. In true experimental design, 22 males wistar rat were divided into control group and treatment group (Beraprost 100mcg/KgBW/day). The results showed that the systolic blood pressure decrease after therapy with Beraprost from 180 mmHg to 143 mmHg whereas diastolic blood pressure consistant at 80 mmHg after induction of hypertension as well as therapy of Beraprost. An examination of cardiac histopathology, there was an increasing number of blood vessels in the treatment group, 16.637.29 compared to 7.45 1.21 in control group. It can be concluded that Beraprost had an angiogenesis effect and decrease systolic blood pressure in hypertensive rat model. Keyword : Hypertension, Beraprost, vascular structure, angiogenesis.
Aktivitas Antioksidan dan Kemampuan Proteksi terhadap Kerusakan DNA dari Protein Isolat Biji Melinjo (Gnetum Gnemon L.) Terhidrolisis Menggunakan Alkalase Terimobilisasi (Antioxidant Activity and Protection Ability Against DNA Damage of Isolate Protein Me Anandini Aulia Safiera; Endah Puspitasari; Tri Agus Siswoyo
Pustaka Kesehatan Vol 5 No 2 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v5i2.5870

Abstract

Hydrolyzed protein isolates of melinjo seed using free alcalase has been known to have antioxidant potential. However, free alcalase can only be used once. Enzymes immobilization technique with entrapment method would overcome this problem. The immobilized enzyme characteristic was observed by SEM and hydrolysis degree value. The success of hydrolysis process was observed by SDS-PAGE. Antioxidant activity test was determined by the ability to inhibit hydroxyl radical and protection against DNA damage in 1% agarose gel. The result showed that protein isolates from melinjo seed had been successfully hydrolyzed by immobilized alcalase. Following hydrolysis showed that immobilized alcalase was effective to hydrolyze protein up to four times. Based on hydroxyl radical reduction activity test, antioxidant activity of hydrolyzed protein using immobilized alcalase had the same as that of glutathione as positive control antioxidant activity. In addition, hydrolyzed protein using immobilized alcalase had the ability toprotect DNA damage which showed by reversible change of supercoil band. Keywords: melinjo seed, hydrolyzed protein, immobilized alcalase, antioxidant
Respon Imunogenitas Protein Permukaan 19 kDa Streptococcus pneumoniae (Immunogenicity Response of Streptococcus pneumoniae 19 kDa Surface Protein) Muhammad Dimas Arya Candra Permana; Dini Agustina; Bagus Hermansyah
Pustaka Kesehatan Vol 3 No 1 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pneumonia is the main common cause of children death in the world. Microbiological studies found the major causes of pneumonia is Streptococcus pneumoniae. Infection of S.pneumoniae influenced by several virulence factors, one of which is surface protein. The purpose of this study was to determine the immunogenicity of 19 kDa S.pneumoniae surface protein through hemagglutination inhibition and adhesion inhibition test. Adhesion inhibition test used antibodies that is formed from surface protein, to inhibit bacterial adhesion to the enterocytes. Hemagglutination inhibition test also used antibodies that formed from surface protein, to inhibit the agglutination of erythrocytes caused by S.pneumoniae. The results showed that antibodies, which was formed from 19 kDa S.pneumoniae surface protein, were able to inhibit hemagglutination process up to 1X dilution. Adhesion inhibition test showed that the higher antibody dilution, the greater the adhesion index. Pearson correlation analysis of the adhesion test showed that there was a significant correlation between antibody dilution with bacterial adhesion index (R= -0,787; p=0,036). It can be concluded that the 19 kDa surface protein of S.pneumoniae was immunogenic.   Keywords: Streptococcus pneumoniae, surface protein, antibody
Pengaruh Vitamin C terhadap Fragilitas Osmotik Eritrosit pada Mahasiswa Kedokteran Universitas Jember yang Mengalami Stres Psikologis Zulfahmi Muslim; Aris Prasetyo; Septa Surya Wahyudi
Pustaka Kesehatan Vol 7 No 1 (2019): Volume 7 No. 1, 2019
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v7i1.17585

Abstract

Medical students are constantly getting stress that could lead to oxidative stress where the level of free radicals is higher than the level of antioxidants in the body. Free radicals can bind to erythrocyte membranes and alter membrane structure that lead to the integrity of the erythrocyte membrane resulting in decreased erythrocyte ability in preventing hemolysis. Vitamin C is an antioxidant that could prevent free radicals bond to erythrocyte membrane. Vitamin C works by donating electrons to free radicals and prevent binding to erythrocyte membranes. The purposed of this study was to determine the effect of vitamin C consumption on osmotic fragility of erythrocytes in medical students with psychological stress. This research was clinical trial research with quasi experimental with pretest-posttest control group design. Researchers used Depression Anxiety Stress Scale (DASS) questionnaire to measure the stress level. Data analysis using T test obtained mean of percentage of hemolysis between pretest and posttest was p= 0,02. It can be concluded that there is significant difference on osmotic fragility due to Vitamin C consumption in medical Student of Jember University with psychological stress.

Page 39 of 63 | Total Record : 621

 37   38   39   40   41 

Filter by Year

2013 2025


Reset
Filter By Issues
All Issue Vol. 13 No. 1 (2025): Volume 13 No. 1, 2025 Vol. 12 No. 3 (2024): Volume 12 No. 3, 2024 Vol 12 No 2 (2024): Volume 10 No.2, 2024 Vol 12 No 1 (2024): Volume 12 No.1, 2024 Vol 11 No 3 (2023): Volume 11 No.3, 2023 Vol 11 No 2 (2023): Volume 11 No.2, 2023 Vol 11 No 1 (2023): Volume 11 No.1, 2023 Vol 10 No 3 (2022): Volume 10 No.3, 2022 Vol 10 No 2 (2022): Volume 10 No.2, 2022 Vol 10 No 1 (2022): Volume 10 No.1, 2022 Vol 9 No 3 (2021): Volume 9 No.3, 2021 Vol 9 No 2 (2021): Volume 9 No.2, 2021 Vol 9 No 1 (2021): Volume 9 No.1, 2021 Vol 8 No 3 (2020): Volume 8 No. 3, 2020 Vol 8 No 2 (2020): Volume 8 No. 2, 2020 Vol 8 No 1 (2020): Volume 8 No. 1, 2020 Vol 7 No 3 (2019): Volume 7 No.3, 2019 Vol 7 No 2 (2019): Volume 7 No. 2, 2019 Vol 7 No 1 (2019): Volume 7 No. 1, 2019 Vol 6 No 3 (2018) Vol 6 No 2 (2018) Vol 6 No 1 (2018) Vol 5 No 3 (2017) Vol 5 No 2 (2017) Vol 5 No 1 (2017) Vol 4 No 3 (2016) Vol 4 No 2 (2016) Vol 4 No 1 (2016) Vol 3 No 3 (2015) Vol 3 No 2 (2015) Vol 3 No 1 (2015) Vol 2 No 3 (2014) Vol 2 No 2 (2014) Vol 2 No 1 (2014) Vol 1 No 1 (2013) More Issue