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e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 621 Documents
Hubungan antara Pola Sidik Bibir dengan Jenis Kelamin pada Mahasiswa Fakultas Kedokteran Gigi Universitas Jember (The Correlation between Lip Prints Pattern and Sexual Dimorphism on Students of Faculty of Dentistry, The University of Jember) Sitti Nur Qomariah; Masniari Novita; Erawati Wulandari
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background:Cheiloscopyisaforensicidentificationtechniquesbasedonpatternsofwrinklesandgroovesonthe mucosalsurface ofthelip, calledlipprints. Theunique characteristicsoflipprintsanditsdifferentamonghumanbeingcouldbeusedinidentifypeople.Objective:Theaimofthisstudyistoidentifywhetherthereisacorrelationbetweenlipprintsinsexualdimorphismof studentsofFacultyofDentistry,TheUniversityofJember,ornot.Method:Thedescriptiveobservationalstudyiscrosssectionalapproach.Thesubjectsofthisstudyare80students,comprisingof40malesand40females.Result:Theresultshowedthatthereweredifferenceslipprintspatternbetweenmaleandfemale. Themostdominantlipprint patternin malewastipeIII 16 (40%), whereasthemostdominantlipprintpatterninfemalewastipeI’14(35%).Conclusion:Thedifferencesoflipprintspatternbetweenmaleandfemaleshowedthatlipprintspatterncouldbeused inforensicidentification.Keywords:forensicidentification,lipprintspattern,sexualdimorphism
Uji Aktivitas Anti Hiperurisemia Ekstrak n-Heksana, Etil Asetat, dan Etanol 70% Biji Jinten Hitam (Nigella sativa) terhadap Mencit Hiperurisemia (Anti Hyperuricemic activity of n-Hexane, Ethyl acetate, and Ethanol 70% of Black Cumin Seed (Nigella sativa) Umar Dian Prambudi Kusuma; Siti Muslichah; Evi Umayah Ulfa
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

The aim of this study was to determine the in vivo anti-hyperuricemic effect of black cumin extract. Black cumin was extracted with n-hexane, ethyl acetate, and ethanol 70% continously. Fifteen mice were divided into five groups K-, K+, P1, P2, and P3. Group K- as negative control (chicken liver juice 0,2 % b/v) and group K+ as positive control (allopurinol 10 mg/kg b.w.). Group P1, P2, and P3 received n-hexane, ethyl acetate, and ethanol 70% black cumin extract. The extracts were given to mice in 200 mg/kg b.w dose for 4 days. The blood samples were taken an hour after potassium oxonate injection (300 mg/kg b.w) to inhibit uricase enzym. The data was collected and analyzed using one way ANOVA and LSD test. The result showed that activity of ethyl acetate extract of black cumin has no significant difference of possitive control. Based on phytochemistry screening it has terpenoid, saponin, and alkaoid. Terpenoid has anti-hyperuricemic effect but its mechanism still unknown.   Keywords: hyperuricemic, Nigella sativa, terpenoid.
Hubungan Kadar SGOT dengan Kadar Leukosit pada Pasien NSTEMI di ICCU RSD dr. Soebandi Jember (Correlation between SGOT Level and Leukocytes in NSTEMI Patients at ICCU dr. Soebandi Hospital, Jember) Finty Arfian; Suryono Suryono; Rini Riyanti
Pustaka Kesehatan Vol 6 No 1 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i1.6797

Abstract

Acute Coronary Syndrome (ACS) is a syndrome that occurs because of blockage of the coronary artery causing clinical symptoms due to unfulfilled oxygen supply. Atherosclerosis is suspected as the main cause of ACS. Inflammation is one pathophysiology of atherosclerosis characterized by leukocytosis. NSTEMI is one spectrum of ACS that diagnosed by anamnesis, ECG, and cardiac marker such as troponin. SGOT is also released into the circulation when there is myocardial damage. Studies has reported that SGOT increased from the normal range during a myocardial infarction. The purpose of this study was to determine the relationship between levels of SGOT and leukocytes in patients with NSTEMI. The sample included 10 patients with NSTEMI in July-December 2016 from ICCU RSD dr. Soebandi Jember. The data was collected from medical record. The result showed that the average of SGOT increased from the normal range, while the average levels of leukocytes were in normal range. Pearson correlation test showed that there was no significant relationship between the two variables with p=0.083>0.05. In conclusion, there was no relationship between the levels of SGOT and leukocytes in patients with NSTEMI at ICCU RSD dr. Soebandi Jember. Keywords: NSTEMI, SGOT, Leukocyte
Pengaruh Pemberian Ekstrak Tauge (Vigna radiata (L)) terhadap Kadar Serum Trigliserida pada Tikus Wistar Jantan yang Diinduksi Kuning Telur (The Effect of Mungbean (Vigna radiata (L)) Sprout on Triglyceride Serum Levels of Male Wistar Rats Induced by Eg Fairuztya Naila Maris; Rena Normasari; Rini Riyanti
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Dyslipidemia is a condition of abnormal blood lipid profiles, including hypertriglyceridemia. One of antidislipidemia agent is niasin, that can be found in mungbean (Vigna radiata (L)) sprout. This study aimed to determine the difference in triglyceride serum after treatment with mungbean sprout extract on male wistar rats induced by egg yolk. This was an experimental study with randomized Post-test Only Control Group Design. Twenty five male wistar rats aged 2-3 months, divided into 5 groups: K(-), K(+), P1, P2 and P3. K(-) was treated with standard diet. The other four groups were injected with 0,006 mg/ 200 gram weight IV adrenalin on the first day followed by egg yolk diet for six weeks. P1, P2, and P3 group were treated with 50, 100, and 200 mg/ 200 g/day of mungbean sprout extract simultaneously with the diet. At the end of the treatment, the serum was taken to examine the triglyceride serum. Average levels of triglycerides serum in group K(-) 69,2±15,9; K(+) 92±14,9; P1 63,2±14,1; P2 53±6,9; P3 84,8±23,9. There was significant different of triglyceride serum means between group K(+) and P2 (p=0,014). In conclusion, 100 mg of mungbean sprout extract showed a significant difference in triglyceride serum with control group of male wistar rats induced with egg yolk.   Keywords: Mungbean sprout, egg yolk, triglyceride
Pengaruh Gel Ekstrak dan Serbuk Mentimun (Cucumis sativus) terhadap Angiogenesis pada Penyembuhan Luka Bakar Derajat IIB pada Tikus Wistar (The Effect of Cucumber (Cucumis sativus) Gel Extract and Powder on Angiogenesis of the IIB Degree-Burn Wound He Ardhina Mahadica Nugroho; Ulfa Elfiah; Rena Normasari
Pustaka Kesehatan Vol 4 No 3 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Burns is a serious global health problem. Annually, 265.000 dead occured because of burns. Local burns wound treatment ideally uses material that can act as antimicrobial and antiinflamation, as well conditions moist environtment. Cucumber contains flavonoid and saponin that enhance Vascular Endothelial Growth Factor that can increase angiogenesis. The purpose of this research was to investigate the effect of cucumber extract gel and cucumber powder gel on number of vascular lumen angiogenesis of IIB-burn wound healing in wistar rat. This research was true experimental laboratories with post test control only design by using wistar rats and divided into 8 groups. Rats were burns-induced and then terminated on the 3rd and the 10th day, each group consist of negative control group (normal saline), positive control group (gentamycin eye ointment), treatment group 1 (cucumber extract gel), treatment group 2 (cucumber powder gel). Data analysis using One Way ANOVA test for the 3rd day and the 10th day on vascular lumen number showed 0,031 and 0,036 (p<0,05) significance respectively. In conclusion, there was significant difference for cucumber extract gel and cucumber powder gel towards vascular lumen number in IIB-burns wound healing in wistar rat. Keywords: Burns, wound healing, angiogenesis, cucumber (Cucumis sativus)
Hubungan antara Kebiasaan Merokok dengan Kejadian Hipertensi di RSD dr. Soebandi Jember (Correlation Between Smoking and the Incidence of Hypertension in Department of Cardiovascular Disease RSD dr. Soebandi Jember) Cici Eirmawati; Wiratmo Wiratmo; Prihwanto Budi S
Pustaka Kesehatan Vol 2 No 2 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Hypertension is one of the non-communicable diseases that becoming a very serious health problems at this time. In Indonesia, approximately 6.8% of the causes of death at all ages due to hypertension. Smoking is one of the risk factor of hypertension. The purpose of this study is to determine correlation between smoking and the incidence of hypertension. The method of this research was a case control study. The sampling technique was the lottery technique. This research was conducted in Department of Cardiovascular Disease RSD dr. Soebandi Jember on May 9 to June 9, 2014 with 44 case respondents and 88 control respondents. The data was analyzed using logistic regression. The test results showed that smoking have a significant association with hypertension; 1) Correlation between smoking and hypertension (Sig. = 0.000; OR = 6.429); 2) Correlation between the number of cigarettes smoked and hypertension (Sig. = 0.000; OR = 2.490); 3) Correlation between the type of cigarettes smoked and hypertension (Sig. = 0.000; OR = 3.519); 4) Correlation between the duration of smoking and hypertension (Sig. = 0.000; OR = 2.902). As a conclusion, there is a correlation between smoking and the incidence of hypertension in men aged 30-60 years in Department of Cardiovascular Disease RSD dr. Soebandi Jember. Keywords: hypertension, smoking, number of cigarettes, type of cigarettes, duration of smoking
Pengaruh Pemberian Cuka Apel 'A' terhadap Kadar MDA Hepar Tikus Wistar Jantan yang Diinduksi Parasetamol Dosis Toksik Niki Niki Rahmawati; Sugiyanta Sugiyanta; Elly Nurus Sakinah
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7667

Abstract

High dose of paracetamol is metabolized by cytochrome P-450 become free radical N-acetyl-p-benzoquinoneimine (NAPQI) but liver Glutathione (GSH) is not adequate to change it become nonreactive metabolite so that NAPQI bind to unsaturated fatty acid of cell membrane, causing lipid peroxidation and increase liver Malondialdehyde (MDA). 'A' apple vinegar contains anthocyanin with an antioxidant effect by electron donor to NAPQI and acetic acid to improve liver GSH level. The aim of research was to investigate the effect of 'A' apple vinegar on the rat liver MDA induced by toxic dose of paracetamol. Research groups consist of normal control (CMC Na 1% 1 ml for 14 days), negative control (CMC Na 1% 1ml for 14 days + paracetamol 291.6 mg/200gBW on the day 12nd,13rd,14th), and treatment group ('A' apple vinegar 0.4 ml/150gBW for 14 days + paracetamol 291.6 mg/200gBW on the day 12nd,13rd,14th). Liver MDA was measured on the day 15th with competitive ELISA. The average of normal control group was 21.58 ng/ml, negative control group was 70,71 ng/ml, treatment group was 37,67 ng/ml. One way ANOVA and Post hoc LSD test showed significantly differences between all groups (p<0,05). It can be concluded that 'A' apple vinegar had an effect on the liver MDA induced by toxic dose of paracetamol. Keywords: Paracetamol, NAPQI, MDA, 'A' apple vinegar, antioxidant
Frekuensi Kegagalan Pengisian Saluran Akar dengan Teknik Preparasi Step Back pada Gigi Berakar Ganda di Rumah Sakit Gigi dan Mulut Universitas Jember 2011-2016 (The Frequency of Failure Root Canal Filling with Step Back PreparationTechnique on Multiple Ro Melisa Novitasari; Raditya Nugroho; Sulistiyani .
Pustaka Kesehatan Vol 5 No 2 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background: Most of root canal preparation use step back technique which form the root canal. Thecool lateral condensation technique is a standard technique taught to students, which has the highestcure rate between 87% - 94% and a root canal filling was ended by 0-2 mm from the radiographic apex,which the underfilling cure rate between 68% - 77% and the overfilling cure rate between 75% -76%.Some research suggests that the molars teeth had the highest frequency of failure in root canal filling.Objective: To identify the frequency of failure in root canal filling with preparation step back techniqueson a double-rooted teeth Dental Hospital of the University of Jember from 2011 until 2016. Methods: Thedesign of this study is a descriptive by gathering medical records. The radiograph pictures of doublerootedteeth which underfilling and overfilling were evaluated by researcher, data was calculated withmanual furthermore data was displayed in tables and graphics. Results and Conclusions: Teeth withunderfilling of 68 teeth larger than teeth that overfilled a total of 18 teeth. The maxillary teeth with themost underfilling are the teeth 14 and the tooth mandibular 46 where as the most overfilled teeth in themaxilla are the teeth 26 and the mandibular is the tooth 46. The percentage of root canal treatmentunderfilling and overfilling is 27.3% Overall number of patients with multiple root canal treatment.Keywords: lateral condensation, overfilling, step back, underfilling
Faktor Yang Berhubungan Dengan Kejadian Hipertensi Pada Akseptor Pil KB Di Kelurahan Sumbersari Kabupaten Jember Tahun 2014 (The Associated Factors of Hypertension Occurence in Oral Contraceptives User at Sumbersari District Area in Jember Regency) Dewi Nafisah; Pudjo Wahjudi; Andrei Ramani
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

The hypertension is the main factor of cardiovascular disease in the world. The hypertension has various factors, one of the risk factors is oral contraceptives use in woman. Prevalence of hypertension have increased 30,73% in 2012 at Jember with a high prevalence at Sumbersari by 1519 woman with hypertension. The purpose of this study is to analyze the association between age, the duration of using oral contraceptives, type of oral contraceptives and regularity blood pressure checkup with hypertension among oral contraceptives user at Sumbersari District Area in Jember Regency in 2014. This research was cross sectional study.The sample was 70 women who use oral contraceptives in last two years. The result is presented in the table, text and analyzed by Chi-Square with the level significance 5% (á=0,05). The result showed that the average respondent with hypertension is an age 37 years old with the duration of using oral contraceptives 8 year. The most type of oral contraceptives which is used contain 0.03-0.05 mg estrogens and most of them is not regularity blood pressure checkup. There are significant associated between age and the duration of using oral contraceptives with hypertension. However, there are not significant associated between type of oral contraceptives and regularity blood pressure checkup with hypertension. Keyword: Oral Contraceptive User, Hypertension
Pengembangan Strip Tes Berbasis Pararosanilina untuk Deteksi Formalin pada Sampel Tahu Alni Riskyna; Bambang Kuswandi; Indah Purnama Sary
Pustaka Kesehatan Vol 6 No 3 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i3.9869

Abstract

Test strip based on pararosaniline has been developed for formaldehyde detection in tofu samples. The test strip as a formaldehyde sensors has been fabricated by immobilizing pararosaniline on whatman filter paper. The test strip was characterized for liniearity, detection limit, quantitation limit, selectivity, accuracy and precision. It has response time at 4 minutes and good liniearity was achieved in the concentration range of 2-80 ppm with correlation coefficient of (r) 0.999. The detection limit and quantitation limit were 0.048 ppm and 0.161 ppm, respectively. The RSD of reproducibility was found 8.04%, where recovery was 80-110%. The life time of the test strip was 14 days when it was stored at 40C. The test strip has been successfully applied to detect formaldehyde in tofu samples. The result also shown in agreement with spectrophotometry uv-vis method. Keywords: formalin, pararosaniline, tofu, immobilization, strip test

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