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Medula
Published by Universitas Lampung
ISSN : -     EISSN : 97726154     DOI : -
Core Subject : Health, Science, Education,
Education Medicine & Pharmacology Neuroscience Public Health
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 24 Documents
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Search results for , issue "Vol 14 No 8 (2024): Medula" : 24 Documents clear
Penggunaan Dinamometer Tangan Sebagai Instrumen Asesmen Klinis Ilhamy, Satria Rizqi; Setiorini, Anggi; Ratna, Maya Ganda; Ismunandar, Helmi
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1254

Abstract

Hand is one of the system organs in the human bodies consisting of bones, muscles, and nerves that works in unison in order to function well. Hand plays a crucial role in daily activities hence it needs to have a good function. One of the main method to assess one’s hand function is by their handgrip strength measured by a hand dynamometer. Hand grip strength measured by a hand dynamometer can be used as a certain health indicator in clinical settings either as a diagnostic tool or as a prognostic predictor for some diseases. One of the use of hand grip strength measured by a hand dynamometer is to diagnose sarcopenia, a musculoskeletal degenerative disease that affects the elderly because of their aging process. Research showed a relationship between a low results of hand grip measurement with an increase of the risk of death in pneumonia patients caused by COVID-19. The results from the dynamometer can also be used as a predictor of success for weaning off a ventilator. Other research also found a correlation between the hand grip measurement with the degree of severity in type 3 spinocerebellar ataxia. Hand grip measurement is relevant for assessing clinical outcomes in patients with incurable cancer. Another study found that hand grip strength measurement can be used to assess chronic kidney disease patient’s vascular diameter for their vascular access in order to continue their hemodialysis. Therefore, dynamometer has a potential as a clinical assessment instrument to support diagnostic and prognostic accuracy.
Article Review: Pendekatan Holistik Manajemen Obesitas: Aspek Psikologis dan Kesehatan Mental Syarel, Radin Ghefira Naura; Berawi, Khairun Nisa; Febriani, Wiwi
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1255

Abstract

Obesity is a complicated and multifaceted medical disorder defined by excess fat buildup, which can have a severe impact on an individual's physical and mental health. In 2022, the World Health Organization (WHO) reported that around 2.5 billion persons globally are overweight, with obesity incidence in Indonesia reaching 23.1%. This number indicates a notable rise and raises major public health concerns. Obesity has a significant effect on a person's mental health, including sadness, anxiety, and low self-esteem, in addition to raising the risk of several chronic diseases like type 2 diabetes, hypertension, and cardiovascular disease. According to recent studies, psychological variables are crucial in the emergence and maintenance of obesity. Unhealthy eating habits, such as consuming foods high in calories and low in nutrients, can be brought on by stress, social stigma, and environmental pressure. As a result, obesity management requires a multidisciplinary strategy that not only focuses on physical therapies such as food and exercise, but also takes into account the psychological factors that influence eating behavior. Acceptance and Commitment Therapy (ACT), which aims to help people manage psychological stress and build mental resilience, is one promising strategy. Accepting challenging emotional situations and resolving to act in line with one's own ideals are the main goals of ACT. It is believed that removing the stigma attached to weight and offering sufficient psychological assistance can enhance the lives of those who suffer from obesity and stop the rise in obesity rates in Indonesia. Better outcomes in controlling this condition can be accomplished by improving our understanding of the link between mental health and obesity and implementing comprehensive intervention techniques. This comprehensive strategy is anticipated to offer a more successful way to deal with the issue of obesity in society by incorporating a number of academic fields, such as psychology, nutrition, and sports.
Literature Review: Manfaat Intervensi Home Visit oleh Tenaga Kesehatan Terhadap Pencegahan Stunting Nadifa, Shallu Afdha; Sutarto, Sutarto; Kusumaningtyas, Intan
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1259

Abstract

Stunting is a condition of children with a type of short stature caused by chronic malnutrition which is related to low socio-economic conditions, lack of nutritional intake, poor maternal health, a history of recurrent illnesses, and child feeding practices that do not meet standards. Stunting can be prevented through optimizing nutrition and health, namely home visit nutritional interventions by health workers. Home visits by health workers or trained cadres carried out during pregnancy or after the baby is born aim to educate parents directly and intensely. A review of the journal is necessary to find out the benefits of home visit interventions in reducing stunting so that the stunting problem in Indonesia can be resolved in an effective way. The method used in this research, the Systemic Literature Review (SLR), comes from national journals and international journals regarding the benefits of home visit interventions in the 2014-2024 time period. The results obtained from this study are that home visits can effectively increase mothers' knowledge and health behavior in caring for their babies and increase fathers' confidence in caring for children. Furthermore, due to the provision of correct parenting practices from health workers to families, home visits have been proven to be able to prevent stunting, increase weight gain, height, and child development scores, be able to increase the average IQ (Intelligence Quotient) score, children's executive function, and make children have higher pre-academic skills.
Pengaruh HbA1c Terhadap Profil Lipid pada Pasien Diabetes Melitus Tipe 2 Suci, Maghfirly Juniarti Eka; Tjiptaningrum, Agustyas; Setiawan, Gigih; Kurniati, Intanri
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1263

Abstract

Diabetes Mellitus (DM) is characterized by a state of hyperglycemia due to insulin resistance, decreased insulin production, or both of these conditions which are classified into metabolic diseases. When checking the condition of type 2 DM, HbA1c can be checked as an indicator. High and uncontrolled HbA1c levels will cause disturbances in lipid profiles such as increased triglycerides, LDL, total cholesterol, and decreased HDL. The purpose of this study is to determine whether or not there is an effect of HbA1c on lipid profiles in type 2 DM patients. This method uses scientific publication search media such as Google Scholar, Pubmed, and old medical scientific journals using the keywords “lipid profile, HbA1c, type 2 diabetes mellitus, and dyslipidemia” obtained 15,700 articles and scientific journals. In patients with type 2 diabetes mellitus, glycemic control can be determined by HbA1c examination, high HbA1c levels are associated with disruption of lipid profile levels. The results of the study discuss the effect of HbA1c levels on lipid profiles in patients with type 2 diabetes and determine the relationship between the two.
Faktor-Faktor Penyebab Terjadinya Syndrome Dyspepsia Pada Remaja Putri Habsari, Maharani Kusuma; Angraini, Dian Isti; Yuningrum, Hesti; Wardani, Dyah Wulan Sumekar Rengganis
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1266

Abstract

One of the most common non-communicable diseases is dyspepsia syndrome. A collection of symptoms in the upper gastrointestinal tract known as dyspepsia syndrome includes pain or discomfort in the upper abdominal area, a burning sensation in the chest, a feeling of fullness and early satiety, nausea, and vomiting. Indonesia ranks third after the United States as the country with the highest prevalence of dyspepsia syndrome, reaching 40–50%. Various risk factors, such as age, gender, dietary patterns, breakfast habits, consumption of spicy and sour foods, fast food, irritative beverages (soda, coffee, alcohol), exercise habits, smoking, nutritional status, and socioeconomic factors, can lead to the occurrence of dyspepsia syndrome. Adolescence is one of the risk factors that influence the occurrence of dyspepsia syndrome. Adolescents who are at higher risk of developing dyspepsia syndrome are those of the female gender. Teenage girls are more likely to pay attention to body shape and have a desire to emulate their online idols, which can lead them to adopt strict diets and irregular eating habits. Excessive physical activity contributes to the poor eating habits and breakfast habits of teenagers. The consumption of unhealthy foods, such as spicy and sharp-flavoured dishes, will increase stomach acid production. Stress in adolescents can be one of the triggers for dyspepsia syndrome. Prolonged stress can disrupt the digestive system and cause symptoms in healthy individuals. Every teenager with a busy schedule must be able to manage their time and schedule to avoid dyspepsia syndrome by bringing a packed lunch during activities.
Review Article: Potensi Farmakologi Bunga Telang (Clitoria ternatea) Athallah, Dimas Rifqi; Rudiyanto, Waluyo; Wijaya, Sofyan Musyabiq; Angraini, Dian Isti
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1267

Abstract

Clitoria ternatea, commonly known as butterfly pea flower, is a tropical plant with high historical and cultural value, particularly in traditional medicine in Indonesia and Asia. This plant is rich in bioactive compounds such as phenols, terpenoids, and alkaloids, which contribute to its various pharmacological activities, including antioxidant, antidiabetic, antihyperlipidemic, anticancer, anti-inflammatory, antimicrobial, hepatoprotective, and neuroprotective effects. The phenolic compounds in the flower function as natural antioxidants, while terpenoids and alkaloids support antidiabetic and anticancer effects. This review aims to evaluate the pharmacological potential of C. ternatea based on literature published in the last decade (2014–2024), sourced from PubMed, Google Scholar, Science Direct, and ResearchGate. Inclusion criteria were articles in English and Indonesian, while exclusion criteria included incomplete access articles, secondary reviews, and studies with weak methodologies. Based on this review, C. ternatea shows great potential as an alternative modern therapy, with consistent research demonstrating significant therapeutic activity and low side effects. Its bioactive compounds work through mechanisms such as enzyme inhibition, glucose regulation, inflammation modulation, and protection from oxidative stress, making it a promising candidate for innovative therapeutic development.
Pengaruh Ekstrak Buah Adas (Foeniculum vulgare) terhadap Pertumbuhan Bakteri Salmonella typhi Secara In Vitro Akbar, Muhammad Zakky Putra; Wijaya, Sofyan Musyabiq; Carolia, Novita; Sukohar, Asep
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1271

Abstract

Bacterial infections, especially those caused by Salmonella typhi, are a global health challenge, including in Indonesia, where there is a high prevalence of typhoid fever. Treatment of this infection generally relies on antibiotics, but increasing antibiotic resistance is becoming a big problem. Therefore, there is a need for alternative treatments that are safer and more effective. This study aims to evaluate the ability of ethanol extract of fennel fruit (Foeniculum vulgare) to inhibit the growth of Salmonella typhi. Extraction was carried out using the maceration method using 70% ethanol, followed by evaporation of the solvent to obtain a stock solution. The extract concentrations tested included 5%, 10%, 20%, 40%, and 80%, with distilled water as a negative control and antibiotics as a positive control. Antibacterial testing was carried out using the disk diffusion method on Mueller Hinton Agar media, and the inhibition zone was measured after 48 hours of incubation. The results showed that fennel fruit extract effectively inhibited the growth of Salmonella typhi at an extract concentration of 20%, with the diameter of the inhibition zone increasing as the concentration increased, reaching 4.75 mm at a concentration of 80%. Statistical tests with Kruskal-Wallis showed significant differences between treatments. This research proves that ethanol extract of fennel fruit has antibacterial potential which can be used as an alternative in treating Salmonella typhi infections, especially considering that it is safer than synthetic antibiotics.
Manfaat Ekstrak Buah Adas (Foeniculum vulgare) Terhadap Bakteri Cutibacterium acnes Amourisva, Azqiya Putri; Carolia, Novita
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1274

Abstract

Fennel fruit (Foeniculum vulgare) is known for its antibacterial properties, making it a promising natural remedy for acne treatment, particularly against Cutibacterium acnes, the primary acne-causing bacterium. The increasing issue of antibiotic resistance highlights the need for safer and more effective natural alternatives. The essential oil of fennel contains major compounds such as anethole (83.64%), fenchone (3.58%), and l-limonene (3.75%), which have been shown to exhibit significant antibacterial activity. Research indicates that a 2% fennel oil concentration produces an inhibition zone of 7.5 mm, while an 8% concentration increases this to 19 mm, demonstrating its effectiveness in inhibiting bacterial growth. In addition to its antibacterial activity, fennel extract also possesses anti-inflammatory properties, which help reduce inflammation and redness caused by acne. Fennel oil-based cream formulations have also been developed, showing good physical stability and strong antibacterial effects against C. acnes. One key advantage of fennel extract is its natural composition, making it safer compared to synthetic antibiotics, which may cause side effects and bacterial resistance. Therefore, fennel extract holds great potential as an active ingredient in anti-acne skincare formulations. However, further research is necessary to confirm its long-term efficacy and applications in cosmetic and pharmaceutical formulations to ensure its safety and benefits for long-term use.
a Comparison Between Dexamethasone and Prednisolone in ARDS Patients: Literature Review Aqil, Faiq Akhmad; Oktarlina, Rasmi Zakiah; Junando, Mirza; Pardilawati, Citra Yuliyanda
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1275

Abstract

During the COVID-19 pandemic, dexamethasone and methylprednisolone are used to treat COVID-19 patients, particularly those who have acute respiratory distress syndrome (ARDS). Numerous studies have demonstrated that dexamethasone significantly improves respiratory function and lowers mortality in COVID-19 patients, particularly those who need mechanical ventilation. Patients with ARDS with COVID-19 who received dexamethasone had fewer days alive and ventilator-free days, according to a randomized study like the CoDEX trial. But methylprednisolone has also demonstrated encouraging outcomes in treating severe COVID-19 pneumonia, particularly when used as a short-term treatment. The dosage and mode of administration of the two medications differ; dexamethasone is more frequently used to treat the systemic inflammation brought on by this viral infection.
Review Article: Antibacterial Activity of Mangrove Lindur Extract (Bruguiera gymnorrhiza) Against Staphylococcus aureus Setyadi, Yudha Putra; Kurniawaty, Evi; Kusumaningtyas, Intan
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1300

Abstract

Infectious diseases remain prevalent in Indonesia, influenced by environmental factors such as poor sanitation, low public awareness of clean and healthy living behaviors, and a tropical climate. Infectious diseases are health issues caused by microorganisms, such as bacteria, viruses, or parasites, that enter the body. Staphylococcus aureus is one of the primary pathogens for humans and can cause various infections. The main treatment for Staphylococcus aureus infections is antibiotics. However, bacterial resistance to methicillin antibiotics (Methicillin-Resistant Staphylococcus aureus or MRSA) is increasingly common in Indonesia. Therefore, alternative antibiotic treatments based on plant-derived compounds are highly needed. One plant with potential antibacterial activity is Bruguiera gymnorrhiza. Commonly known as bakau lindur, various parts of Bruguiera gymnorrhiza, such as its bark, leaves, and roots, have antibacterial properties. This is attributed to the bioactive compounds present in its extracts, including flavonoids, saponins, alkaloids, phenols, steroids, terpenoids, and tannins.. This article aims to determine whether Bruguiera gymnorrhiza extract exhibits antibacterial activity against Staphylococcus aureus. Based on the literature review, Bruguiera gymnorrhiza extract has been proven to possess antibacterial activity against Staphylococcus aureus. The best antibacterial activity was observed in the 96% ethanol extract of Bruguiera gymnorrhiza bark at a concentration of 15,000 ppm, resulting in a 13.62 mm inhibition zone categorized as strong.

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