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Jurnal Ilmiah Farmasi
Published by Universitas Islam Indonesia
ISSN : 16938666     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
JIF merupakan jurnal yang dikelola oleh Prodi Farmasi Universitas Islam Indonesia, dan diterbitkan dua kali dalam setahun. Jurnal ini dirancang sebagai sarana publikasi penelitian yang mencakup secara rinci sejumlah topik dalam bidang farmasi yang berkaitan dengan farmasi sains dan teknologi serta klinik dan komunitas. Jurnal ini menyediakan sebuah forum sebagai sarana pertukaran gagasan dan dan informasi antar peneliti, akademisi dan praktisi sehingga diharapkan mampu mendukung dan menginisiasi berbagai penelitian terkini yang terkait dengan ilmu kefarmasian. Hasil penelitian yang disajikan dalam jurnal ini diharapkan dapat memberikan kontribusi bagi perkembangan ilmu di bidang farmasi dan kesehatan.
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Articles 13 Documents
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Search results for , issue "2023: Special Issue" : 13 Documents clear
Hubungan pengetahuan dan tindakan vaksinasi COVID-19 di Kecamatan Martapura Timur Abdurrahman Sidiq sidiq; Esty Restiana Rusida; Eny Hastuti
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art1

Abstract

Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the infectious disease causes Coronavirus Disease 2019 (COVID-19). The risk of transmission of COVID-19 in the community is increasing. Therefore, it is necessary to carry out educational interventions related to the application of health procedures and vaccination measures. Vaccination activities are expected to inhibit the spread of and prevent the COVID-19 virus. Objective: This study aimed to determine the relationship between knowledge and COVID-19 vaccination behavior in East Martapura Regency.Method: This study was non-experimental analytical descriptive research using a cross-sectional approach in the East Martapura Regency. The questionnaires were given to 397 respondents. A chi-square test was used to analyze the correlation between the study variables.Results: Most respondents (66.5%) showed average knowledge about the COVID-19 vaccination. More than fifty percent (66.6%) of respondents had inappropriate behavior towards the COVID-19 vaccination. There was a relationship between knowledge and behavior regarding COVID-19 vaccination (p < 0.001).Conclusion: There was a relationship between knowledge and COVID-19 vaccination behavior in East Martapura Regency.
PERBANDINGAN KADAR GLUKOSA DARAH DAN HBA1C PADA INSULIN GLARGINE DAN DETEMIR PASIEN DIABETES MELITUS TYPE 2 DI RUMAH SAKIT UMUM DAERAH ULIN BANJARMASIN helmina wati; Karunita Ika Astuti; Syahrizal Ramadhani; Guntur Kurniawan; Aprilia Rahmadina; Sari Wahyunita
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art5

Abstract

Background: Based on the International Diabetes Federation, the prevalence of diabetes in 2030 will be around 438 million people. In 2019, type 2 diabetes mellitus caused 4.2 million deaths in the world. Diabetes mellitus is a metabolic disorder that requires long-term therapy. Insulin is one of the therapies for type 2 diabetes mellitus. Parameters for monitoring the success of therapy were plasma glucose levels and Hba1c values.Objective: This study aimed to compare the values of plasma glucose and glycosylated hemoglobin (Hba1c) in insulin glargine and detemir patients with type 2 diabetes mellitus (DM) at Ulin Regional Public Hospital, Banjarmasin.Method: This study used a cross-sectional study design in March-May 2022 in 60 patients with type 2 DM at Ulin Regional Public Hospital, Banjarmasin. The data taken was in the form of fasting plasma glucose (FPG), 2-hour post-load plasma glucose (OGTT), and Hba1c values for 12 weeks. Statistical analysis was performed using the Mann-Whitney test with a confidence level of 95%. Results: The results showed that the average pre-post glargine FPG values were 212-139,6 mg/dL and the pre-post detemir FPG values were 224.6-159.8 mg/dL. Hba1c values in patients using glargine pre-post were 9.1% and 8.3%, and the average Hba1c values on insulin detemir pre-post were 9.28% and 8.29%.Conclusion: In therapy using insulin glargine compared to detemir, there was no significant difference between KGDP, KGD2PP, and Hba1C (p> 0.05). Intisari Latar belakang: Berdasarkan International Diabetes Federation (IDF), prevalensi DM tipe 2 tahun 2030 berkisar 438 juta orang. Pada tahun 2019, DM tipe 2 menyebabkan 4,2 juta kematian di dunia. Diabetes mellitus merupakan penyakit gangguan metabolisme yang membutuhkan terapi jangka panjang, dan insulin merupakan salah satu terapi DM tipe 2. Parameter untuk monitoring keberhasilan terapi dapat dilihat berdasar nilai kadar glukosa darah dan nilai Hba1c. Tujuan: Membandingkan nilai Kadar Glukosa Darah Puasa (KGDP), Kadar Glukosa Darah 2 jam Post Prandial (KGD2PP), dan Hba1c pada insulin glargine dan insulin detemir pasien DM tipe 2 di Rumah Sakit Umum Daerah (RSUD) Ulin, Banjarmasin.Metode: Penelitian menggunakan rancangan cross sectional selama bulan Maret-Mei 2022 pada 60 pasien rawat jalan DM tipe 2 di RSUD Ulin Banjarmasin. Data yang diambil berupa nilai KGDP, KGD2PP dan Hba1c selama 12 minggu. Analisis statistik dilakukan menggunakan analisis mann-whitney test dengan tingkat kepercayaan 95%. Hasil: Hasil penelitian menunjukkan nilai rata-rata nilai KGDP glargine pre-post adalah 212 – 139,6 mg/dL dan nilai KGDP detemir pre-post adalah 224,6 – 159,8 mg/dL. Hba1c pada pasien yang menggunakan glargine pre-post adalah 9,1% dan 8,3% serta rata-rata nilai Hba1c pada insulin detemir pre-post adalah 9,28% dan 8,29%.Kesimpulan: Terapi menggunakan insulin glargine dibandingkan detemir tidak terdapat perbedaan yang signifikan antara nilai KGDP, KGD2PP, dan Hba1C p>0,05).Kata kunci: KGDP, KDG2PP, Hba1c, glargine, detemir
Kajian in silico aktivitas antioksidan-antikanker senyawa fenolik dan flavonoid spesies mangifera menggunakan molecular docking PLANTs: Bahasa Indonesia Hafiz Ramadhan; Dyera Forestryana; Putri Indah Sayakti; Mahmud Riyad; Ratna Restapaty
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art2

Abstract

Background: The development of science and technology has created a study of anticancer drug discovery through molecular docking. This method can be applied to screening natural compounds that have antioxidant properties as anticancer candidates.Objective: The aim of the in-silico study is to find out the potential antioxidant-anticancer activities using molecular docking of phenolic and flavonoid compounds contained in the Mangifera species.Methods: Mangiferin, homomangiferin, isomangiferin, quercitrin, kaempferol 3-O-glucoside, catechin, epicatechin, daidzein, genistein, α-tocopherol, gallic acid as the test compounds and Vitamin C, doxorubicin, and hydroxyurea as comparison were prepared with MarvinSketch. The targeted protein data bank (PDB) codes used are 1V4S, 1XAN, 2BEL, 4K7O, 5M2F, 6COX, and 2W3L which were prepared with YASARA. The prepared compounds and proteins docked with each other using PLANTs software.Result: The in-silico results showed that only vitamin C can exceed the native ligand docking against the 1V4S receptor. α-tocopherol has a better binding affinity compared to vitamin C on 1XAN, 2BEL, and 5M2F but could not reach the native ligand score. All of the test compounds have potential antioxidant activity against the 4K7O protein receptor, but α-tocopherol is the only one that has the ability to inhibit the 6COX protein receptor. α-tocopherol also has better anticancer activity against breast cancer initiator (2W3L) compared to other test compounds, doxorubicin, hydroxyurea, and native ligands. Conclusion: The conclusion is that α-tocopherol has the most potential as an antioxidant and anticancer candidate through in silico studies.
Pengaruh Perbedaan Pelarut dan Optimasi Waktu Inkubasi Bakteri Propionibacterium acnes Terhadap Ekstrak Etanol 96% Umbi Bawang Dayak (Eleutherine americana Merr.) M. Andi Chandra; Didik Rio Pambudi; Fitriyanti; Siti Kholilah; Wahyudin Bin Jamaludin
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art7

Abstract

Background: Acne (acne vulgaris) is still a major health problem. Treatment with antibiotics raises problems in the form of resistance, irritation, and immune hypersensitivity. Alternatives derived from natural ingredients are needed to avoid these problems, namely Dayak onions.Objective: To find out the activity of the ethanol extract of onion bulbs in inhibiting the growth of P. acnes based on the variation of the incubation time duration of the bacteria as well as the solvent.Method: Phytochemical screening tests looked for alkaloids, flavonoids, phenols, steroids, tannins, and saponins. Testing of the extract’s ability to inhibit bacteria was carried out with variations in the incubation times (24 and 48 hours) and solvents, namely Na-CMC and DMSO. The bacteria growth inhibition test employed the well-diffusion method, and the resulting data was analyzed using SPSS software.Results: Dayak onion extract contains alkaloids, saponins, flavonoids, and triterpenoids. Na-CMC solvent obtained the highest inhibition ability of Dayak onion extract at a concentration of 40% with an inhibition value of 10.12±1.840mm (24 hours), and 11.575±1.694 mm (48 hours) while DMSO solvent showed the highest inhibition at a concentration of 20% with inhibition values of 15.48±1.198 mm (24 hours) and 15.91±1.625 mm (48 hours). Interpretation of the results of the Wilcoxon test based on ranking showed a positive difference at 48 hours of incubation.Conclusion: The optimal incubation time of P. acnes was 48 hours with dimethyl sulfoxide (DMSO) as the best solvent. Intisari Latar belakang: Jerawat (acne vulgaris) masih menjadi masalah kesehatan utama. Penannganan dengan antibiotik memunculkan masalah berupa resistensi, iritasi hingga imunohipersensitivitas. Diperlukan alternatif yang berasal dari bahan alam untuk menghindari masalah-masalah tersebut, yaitu bawang dayak (Eleutherine americana Merr.). Tujuan: mengetahui aktivitas ekstrak etanol umbi bawang Dayak dalam menghambat pertumbuhan P. acnes berdasar variasi lama waktu inkubasi bakteri P. acnes dan variasi pelarut.Metode: Pengujian skrining fitokimia meliputi uji alkaloid, flavonoid, triterpenoid, tanin dan saponin. Pengujian aktivitas ekstrak dalam menghambat bakteri dilakukan dengan variasi waktu inkubasi yaitu 24 jam dan 48 jam, serta penggunaan pelarut yang berbeda yaitu Na-CMC dan DMSO. Uji penghambatan bakteri menggunakan metode difusi sumuran dan dilanjutkan dengan analisis data menggunakan SPSS.Hasil: Ekstrak bawang dayak mengandung alkaloid, saponin, flavonoid dan triterpenoid. Pengujian menggunakan pelarut Na-CMC didapatkan kemampuan hambat esktrak bawang dayak tertinggi pada konenstrasi 40% dengan nilai penghambatan 10,12±1,840mm (inkubasi 24jam) dan 11,575±1,694mm (inkubasi 48jam) sedangkan dengan pelarut DMSO didapatkan daya hambat tertinggi pada konsentrasi 20% dengan nilai penghambatan 15,48 ±1,198mm (inkubasi 24jam) dan 15,91±1,625mm (inkubasi 48jam). Interpretasi hasil dari uji Wilcoxon berdasarkan peringkat, menunjukkan perbedaan yang positif pada inkubasi 48 jam. Kesimpulan: Berdasarkan hasil penelitian ini diperoleh waktu inkubasi optimal dari bakteri P. acnes adalah 48 jam dengan pelarut terbaik yang dapat digunakan adalah dimetil sulfoksida (DMSO).Kata kunci: Bawang Dayak, antibakteri, DMSO, Na-CMC, waktu inkubasi
ANALISIS KUALITAS PELAYANAN KEFARMASIAN DAN TINGKAT KEPUASAN PASIEN BADAN PENYELENGGARA JAMINAN SOSIAL ( BPJS) DI RSUD HADJI BOEJASIN PELAIHARI Depy Oktapian Akbar; Rahmayanti Fitriah; Muhammad Luthfi Aditya; Reny Marliadi; Wahyudi; Aesty Rahayu
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art13

Abstract

Background: Pharmaceutical services are services that are provided directly and responsibly to patients, related to medicines, to achieve accurate results that enhance patient quality of life. Hospitals are required to provide health services that meet optimal service standards. The quality of service in the hospital is very important because, with good service, patient satisfaction will also have a positive impact on the hospital.Objective: The purpose of this research is to analyze the quality of pharmaceutical services and the level of satisfaction of BPJS patients at Hadji Boejasin Pelaihari Hospital.Method: A cross-sectional survey design with a targeted sampling design was used in this study. The research method was a questionnaire containing structured questions to quantify each variable studied. Results: According to the quality survey results, pharmaceutical services were 85.96% (according) and 14.03% (not appropriate), while patient satisfaction had a reliability dimension of 78.63% (very satisfied), responsiveness of 77.82% (very satisfied), assurance of 83.01% (very satisfied), empathy of 80.47% (very satisfied), and tangible of 82.53% (very satisfied).Conclusion: From the average of the five dimensions, a result of 547.4 was obtained with an average patient satisfaction index of 80.49% Intisari Latar belakang: Pelayanan kefarmasian di rumah sakit merupakan kegiatan yang memberikan bantuan secara spontan, konsekuen dan konsisten untuk pasien mengenai obat-obatan agar hasil yang diperoleh sahih dan bermanfaat untuk menaikkan mutu hidup pasien menjadi lebih baik. Rumah sakit dituntut untuk memberikan pelayanan kesehatan yang memenuhi standar pelayanan yang optimal. Kualitas pelayanan di rumah sakit merupakan hal yang sangat penting karena dengan pelayanan yang baik maka kepuasan pasien juga akan berdampak positif bagi rumah sakit.Tujuan: Studi ini bertujuan untuk mengetahui kualitas pelayanan kefarmasian dan tingkat kepuasan pasien BPJS di RSUD Hadji Boejasin Pelaihari. Metode: Studi ini menggunakan rancangan survey cross sectional dengan memanfaatkan desain purposive sampling. Instrumen penelitian adalah kuesioner yang berisi pertanyaan terstruktur untuk menghitung setiap variabel yang diteliti.Hasil: Hasil penelitian pada kualitas pelayanan kefarmasian sebesar 85,96% (sesuai) dan 14,03% (tidak sesuai), sedangkan untuk tingkat kepuasan pasien pada dimensi reliability 78,63% (sangat puas), responsiveness 77,82% (sangat puas), assurance 83,01% (sangat puas), empathy 80,47% (sangat puas), dan tangible 82,53% (sangat puas).Kesimpulan: Dari rata-rata lima dimensi diperoleh hasil sebesar 547,4 dengan indeks rata – rata tingkat kepuasan pasien sebesar 80,49%.Kata kunci: BPJS, kualitas pelayanan, tingkat kepuasan
Bioactivity Guided Isolation from Ethanolic Extract of Faloak Stem Bark (Sterculia quadrifida R.Br) Jennifer Ruskim; Ryanto Budiono; Kartini; Nina Dewi Oktaviyanti; Finna Setiawan
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art11

Abstract

Background: Free radicals consist of one or more unpaired electrons in an outer orbit that causes them to be more reactive. This will lead to oxidative stress, which is one of the major causes of degenerative diseases such as cancer, diabetes mellitus, and stroke. Therefore, consuming sufficient antioxidants can prevent oxidative stress. Faloak (Sterculia quadrifida R. Br.) is one of the endemic medicinal plants in East Nusa Tenggara and is a resource of antioxidants that are supported by scientific evidence. Until now, information about the antioxidant compounds in Faloak was limited. Objective: This study aims to identify active compounds in an 80% ethanol extract from faloak bark as antioxidants based on their TLC-bioautography profiles using an ABTS assay. Method: The methods of this study start with the preparation of simplicia, fractination using kinetic maceration, compound group identification and TLC-bioautography, separation using column chromatography [stationary phase: silica H60; mobile phase: 2-propanol: chloroform: acetic acid glacial (5:1:0,5)], identification using a UV-Vis spectrophotometer, and antioxidant activity determination of the extract and isolate using an ABTS assay. Result: Through this study, a subfraction (SFFE A) with a brown-red color and a blue spot under UV 365 nm and an Rf value of 0.65 was obtained. This subfraction (SFFE A) was predicted to be a polyphenol compound. The inhibition percentages of 125, 250, and 500 ppm successively are 80,93%; 95,54%; and 96,69%.Conclusion: The active isolate of ethanol extracting 80% of the faloak stem bark is suspected to be a polyphenol group and has strong antioxidant activity. Intisari Latar belakang: Radikal bebas merupakan suatu molekul yang terdiri atas satu atau lebih elektron tanpa pasangan pada orbital terluar. Hal ini dapat menyebabkan tubuh mengalami stress oksidatif sehingga memicu munculnya berbagai penyakit degeneratif, seperti kanker, diabetes mellitus, serta stroke. Oleh karena itu, dengan mengonsumsi antioksidan yang cukup dapat mencegah stres oksidatif. Faloak (Sterculia quadrifida R. Br.) merupakan salah satu tanaman obat endemik di NTT (Nusa Tenggara Timur) yang berpotensi digunakan sebagai sumber antioksidan kuat yang didukung oleh studi ilmiah. Hingga saat ini, informasi terkait senyawa yang berperan langsung sebagai antioksidan pada tanaman ini masih terbatas. Tujuan: Penelitian ini bertujuan untuk mengidentifikasi senyawa aktif dari ekstrak etanol 80% kulit batang faloak yang berperan sebagai antioksidan berdasarkan profil KLT-bioautografi dengan metode ABTS. Metode: Metode kerja dimulai dengan preparasi simplisia, fraksinasi dengan metode maserasi kinetik, identifikasi golongan senyawa dan KLT bioautografi, pemisahan dengan kromatografi kolom [(fase diam: silika H60; fase gerak: 2-propanol:kloroform:asam asetat glasial (5:1:0,5)], dan identifikasi senyawa menggunakan spektrofotometer UV-Vis, dan pengujian aktivitas antioksidan pada ekstrak dan isolate menggunakan metode ABTS. Hasil: Melalui penelitian ini, didapatkan subfraksi (SFFE A) berwarna merah-kecoklatan yang memiliki noda berfluoresensi biru pada UV 366 dengan nilai Rf 0,65 dengan pengamatan UV 365 nm. Sub fraksi (SFFE A) yang didapatkan diduga merupakan senyawa golongan polifenol. Persentase inhibisi subfraksi pada konsentrasi 125, 250, dan 500 ppm secara berturut-turut adalah 80,93; 95,54; dan 96,69%. Kesimpulan: Isolat aktif dari ekstrak etanol 80% kulit batang faloak diduga merupakan golongan polifenol dan memiliki aktivitas antioxidan yang kuat. Kata kunci: faloak (Sterculia quadrifida R.Br), antioksidan, isolasi, maserasi kinetik, kromatografi kolom
Uji Aktivitas Antioksidan Ekstrak Etanol 70% dan 96% Kulit Batang Tandui (Mangifera rufocostata Kosterm.) dengan Metode DPPH Revita Saputri; Eka Fitri Susiani; Souva Asvia
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art8

Abstract

Background: The genus Mangifera has been reported to have many activities as a natural antioxidant; one of them is the tandui plant (Mangifera rufucostata Kosterm). The study of 70% and 96% ethanol extracts of tandui leaves has shown potential as an antioxidant with the DPPH method, which is a strong category. The potential as an antioxidant in leaves is also possible in other parts, such as stem bark.Objective: This study is to determine the antioxidant potential of tandui stem bark in 70% and 96% ethanol solvents with the DPPH method.Methods: The tandui stem bark was extracted using the soxhletation method with 70% and 96% ethanol solvents. Potential antioxidant activity was measured using a UV-Vis spectrophotometer and the positive control, quercetin.Results: Antioxidant activity results showed that the IC50 of 70% ethanol extract of tandui stem bark (EE70%KBT) was 9.657 µg/mL, the IC50 of 96% ethanol extract of tandui stem bark (EE96% KBT) was 6.362 µg/mL and the IC50 of positive control quercetin was 3.441 µg/mL.Conclusion: The results showed that tandui stem bark extracted using 70% and 96% ethanol has a strong potential as a natural antioxidant (very strong category) using the DPPH method. Intisari Latar belakang: Genus Mangifera dilaporkan telah memiliki banyak aktivitas sebagai antioksidan alami, salah satu jenis dari genus tersebut adalah tumbuhan tandui (Mangifera rufocostata Kosterm.). Penelitian terhadap ekstrak etanol 70% dan 96% daun tandui telah terbukti berpotensi sebagai antioksidan dengan metode DPPH dengan kategori kuat. Potensi sebagai antioksidan pada daun juga dimungkinkan pula pada bagian lainnya seperti kulit batang. Tujuan: Tujuan penelitian ini adalah melihat potensi antioksidan kulit batang tandui menggunakan pelarut etanol 70% dan etanol 96% dengan metode DPPH.Metode: Kulit batang tandui diekstraksi secara sokletasi dengan pelarut etanol 70% dan etanol 96%. Potensi aktivitas antioksidan dianalisis menggunakan spektrofotometer UV-Vis dan kontrol positif yaitu kuersetin. Hasil: Hasil penelitian menunjukkan bahwa nilai IC50 ekstrak etanol 70% kulit batang tandui (EE70%KBT) sebesar 9,657 µg/mL, nilai IC50 ekstrak etanol 96% kulit batang tandui (EE96%KBT) sebesar 6,362 µg/mL dan nilai IC50 kontrol positif kuersetin yaitu 3,441 µg/mL.Kesimpulan: Hasil penelitian tersebut menunjukkan bahwa kulit batang tandui yang diekstraksi menggunakan etanol 70% dan etanol 96% memiliki potensi yang besar sebagai antioksidan alami (kategori yang sangat kuat) berdasarkan metode DPPH.Kata kunci : Mangifera rufocostata Kosterm., kulit batang tandui, antioksidan, DPPH
The relationship between patient knowledge and behavior of NSAID self-medication at Pharmacy X in Banjarmasin Guntur Kurniawan; Muhammad Reza Pahlevi; Helmina Wati; Wulan Ageng Sujatmiko
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art10

Abstract

Background: Self-medication is a way of providing treatment for oneself without a doctor's prescription or the unwanted effects of a drug. Knowledge about diseases and drugs is needed to determine the right behavior for self-medication. One of the drugs used by the public is the non-steroidal anti-inflammatory drug (NSAID).Objective: The purpose of this research was to evaluate the correlation between patient knowledge of using NSAIDs and patient behavior at Pharmacy X, located in Banjarmasin. Method: This research used a quantitative method with a cross-sectional approach. This study included 40 patients who visited Pharmacy X in Banjarmasin for 1 month. The respondents were enrolled using the accidental sampling technique. The data was obtained with a questionnaire and analyzed with the Pearson Chi Square method. Results: The outcomes of this study indicated that the knowledge level of respondents on NSAIDs was classified as poor (40%). The behavior of subjects who use NSAIDs for self-medication was categorized as negative (62.5%). This study also showed an association between knowledge and habits of self-medication using NSAIDs at pharmacy X in Banjarmasin, with a significance value of 0.003 (p <0.05).Conclusion: There is a direct proportional relationship between knowledge and self-medication behavior when taking NSAIDs, with a significance value of 0.003 (p < 0.05). Intisari Latar belakang: Swamedikasi adalah cara melakukan pengobatan sendiri tanpa resep dokter maupun pengetahuan tentang reaksi obat yang tidak diinginkan. Pengetahuan tentang penyakit dan obat sangat dibutuhkan untuk menentukan perilaku yang benar dalam pemilihan obat secara mandiri. Salah satu jenis obat yang digunakan oleh masyarakat adalah obat golongan Non-Steroidal Anti-Inflammatory Drugs (NSAID).Tujuan: Penelitian bertujuan untuk mengetahui hubungan antara pengetahuan pasien tentang swamedikasi obat golongan NSAID dengan perilaku pasien di Apotek X Banjarmasin.Metode: Penelitian ini menggunakan metode kuantitatif dengan pendekatan cross-sectional. Studi ini melibatkan 40 responden yang berkunjung di Apotek X Banjarmasin selama 1 bulan. Pengambilan sampel menggunakan teknik accidental sampling. Pengumpulan data menggunakan kuesioner dan data dianalisis dengan uji Pearson Chi Square.Hasil: Hasil riset menunjukkan bahwa pengetahuan responden tentang NSAID termasuk dalam kategori “kurang baik” sebanyak 40%. Perilaku pasien yang menggunakan swamedikasi obat NSAID termasuk dalam kategori “berperilaku negatif” sebanyak 62,5%. Pengetahuan berhubungan dengan perilaku swamedikasi NSAID di Apotek X Banjarmasin dengan nilai signifikansi 0,003 (p<0,05). Kesimpulan: Pengetahuan pasien berbanding lurus dengan perilaku swamedikasi obat golongan NSAID.Kata kunci: tingkat pengetahuan, perilaku, swamedikasi, NSAID
Analisis Guessability Score dan Pemahaman Piktogram Kefarmasian pada Pasien Tuberkulosis Ema Rachmawati; Dhea Nanda Aliefia; Fransiska Maria Christianty
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art3

Abstract

Background: Pharmaceutical pictograms can be used to help tuberculosis patients understand treatment information, especially those with low reading skills.Objective: This study aimed to analyze the guessability score and the level of understanding of pharmaceutical pictograms related to the use of TB drugs.Method: This was an observational study with a cross-sectional design. The sample used was 96 TB patients who were actively undergoing treatment. The guessability score and level of understanding were analyzed descriptively, while the relationship between socio-demographic characteristics and the level of understanding of pharmaceutical pictograms was analyzed using the Chi-square test.Results: The results showed that the guessability score of 23 pictograms tested on respondents varied greatly, with a score range of 29.2%–99%. Meanwhile, the level of respondents' understanding of pharmaceutical pictograms related to TB treatment was in the "fair" category. The Chi-square test showed a significant relationship between the level of respondents’ education and their understanding of pharmaceutical pictograms.Conclusion: The findings of this study demonstrated that not all pictogram images were simple for respondents to understand. It is necessary to choose pictogram images that are easy for respondents to understand or redesign pictogram images so that they can be used to improve the effectiveness of drug information delivery to patients. Intisari Latar belakang: Gambar piktogram kefarmasian dapat digunakan untuk membantu pasien tuberkulosis memahami informasi pengobatan, khususnya untuk pasien dengan tingkat literasi rendah. Tujuan: Penelitian bertujuan untuk mengukur kemampuan menerka (guessability score) dan pemahaman responden terhadap piktogram kefarmasian terkait pengobatan tuberkulosis.Metode: Penelitian observasional cross-sectional terhadap 96 responden pasien TB yang aktif menjalani pengobatan. Guessability score dan tingkat pemahaman dianalisis secara deskriptif, sedangkan hubungan karakteristik sosio-demografi dengan tingkat pemahaman dianalisis dengan uji Chi-square.Hasil: Hasil penelitian menunjukkan kemampuan menerka (guessability score) terhadap 23 gambar piktogram sangat beragam, dengan rentang skor 29,2% – 99%. Sedangkan tingkat pemahaman responden terhadap piktogram kefarmasian terkait pengobatan TB masuk dalam kategori “cukup”. Uji Chi-square menunjukkan adanya hubungan yang signifikan antara tingkat pendidikan terhadap tingkat pemahaman responden.Kesimpulan: Tidak semua gambar piktogram kefarmasian mudah dipahami oleh responden. Untuk itu perlu memilih gambar piktogram yang mudah dipahami reponden atau melakukan desain ulang gambar piktogram sehingga dapat digunakan untuk meningkatkan efektivitas pemberian informasi obat pada pasien.Kata kunci: guessability score, pemahaman, piktogram kefarmasian, tuberculosis
Pengetahuan, sikap, dan perilaku konsumsi suplemen dan obat tradisional mahasiswa Universitas Jember saat pandemi COVID-19 Dhita Evi Aryani; Agnes Jovanka; Ema Rachmawati; Sinta Rachmawati; Ika Norcahyanti; Antonius Nugraha Widhi Pratama; Afifah Machlaurin; Fransiska Maria C.
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art6

Abstract

Background: The COVID-19 pandemic has been going on for 3 years since it was established by the WHO in 2020. COVID-19 can be prevented by improving the immune system by consuming supplements and traditional medicines.Objective: This study aimed to determine knowledge, attitudes, and behaviors towards supplements and traditional medicines used by Jember University students during the COVID-19 pandemic.Method: This research design was a cross-sectional observational analytic study. The sample size was 606 Jember University students. Samples were taken using the convenience sampling method with online questionnaire instruments. The data obtained were analyzed by Chi-Square, Fisher’s Exact, and descriptive.Results: During the pandemic, 45.9% of respondents consumed supplements and/or traditional remedies to maintain health (80.6%). Knowledge and attitudes showed a significant difference (p≤0.05), so it was concluded that knowledge affects attitudes towards supplements and traditional medicines used. Supplement use behavior showed that some were taking supplements and some were not for various reasons.Conclusion: The majority of respondents have knowledge and attitudes in the medium category. Sociodemographic factors that influence the knowledge and attitudes of Jember University students toward supplements and traditional medicine used during the COVID-19 pandemic were level of education and discipline. Respondents' behavior showed that most of them did not take supplements because they had been vaccinated. Intisari Latar belakang: COVID-19 sudah berlangsung selama 3 tahun semenjak WHO menetapkan sebagai pandemi di tahun 2020. COVID-19 dapat dicegah dengan meningkatkan daya tahan tubuh yang salah satu caranya adalah mengkonsumsi suplemen dan obat tradisional.Tujuan: Penelitian ini bertujuan mengetahui pengetahuan, sikap, dan perilaku konsumsi suplemen dan obat tradisional mahasiswa Universitas Jember saat pandemi COVID-19. Metode: Penelitian ini bersifat analitik observasional dengan jumlah sampel 606 mahasiswa Universitas Jember dengan desain cross-sectional yang diambil metode convenience sampling dengan instrumen pengumpulan data berupa kuesioner daring. Data yang didapatkan dianalisis dengan uji Chi-square, Fisher’s Exact dan deskriptif. Hasil: Terdapat 45,9% responden mengkonsumsi suplemen dan/atau obat tradisional selama masa pandemi untuk untuk menjaga kesehatan (80,6%). Pengetahuan dan sikap menunjukkan perbedaan signifikan (p≤0,05), sehingga diketahui bahwa pengetahuan dapat memengaruhi sikap. Perilaku pengunaan suplemen menunjukkan ada yang mengkonsumsi suplemen dan ada yang tidak dengan berbagai alasan.Kesimpulan: Mayoritas responden mempunyai pengetahuan dan sikap dalam kategori sedang (45,5%; 50,8%), dengan faktor sosiodemografi yang memengaruhi pengetahuan dan sikap mahasiswa Universitas Jember dalam konsumsi suplemen dan obat tradisional adalah tingkat pendidikan dan rumpun ilmu. Perilaku responden menunjukkan mayoritas mereka tidak mengkonsumsi suplemen karena sudah vaksin.Kata kunci: Pengetahuan, perilaku, suplemen, obat tradisional, mahasiswa, COVID-19

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