Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Folia Medica Indonesiana

FMI
Website

Published by Universitas Airlangga

ISSN : 23558393 EISSN : 2599056X DOI : -

Core Subject : Education,

Other

Folia Medica Indonesiana publishes articles in the field of medical science in particular and health sciences in general, as well as a variety of other fields related to those two disciplines. Most of the articles are research article, and others are articles on case reports and literature review. In their presentation in the journal, the articles have passed meticulous editing process by the editors and review process and by competent peer reviewers, with national and international reputation, making the articles presented in this journal qualified, updated, and informative.

Arjuna Subject : -

Articles 547 Documents

4 5 6 7 8

RELATION BETWEEN LENGTH OF STAY AND ANTI-FILARIAL IgG4 LEVEL IN PONDOK GEDE SUB-DISTRICT, BEKASI DISTRICT, WEST JAVA Susatyo, Jeffry Adijaya; Wibowo, Heri
Folia Medica Indonesiana Vol. 53 No. 3 (2017): September 2017
Publisher : Universitas Airlangga

Filariasis is a contagious disease caused by worms of the genus Filaria which transmitted through the bite of various species of mosquitoes. In Indonesia, the existence of filariasis cases are still very concerning. Jati Sampurna and Jati Karya villages in Pondokgede Sub-district, Bekasi District, West Java have been known as filariasis endemic area. Length of stay is presumed as one of many factors that affects filariasis occurrence in those villages. This study aimed to determine the distribution of anti-filarial IgG4 on the region and its comparison with the length of stay and residence status. This study was based on secondary data. Secondary data were obtained from primary research data done by cross-sectional method. These data were used to assess the correlation of filarial infection risk factors in pregnant women living in endemic areas based on the distribution of anti-filarial IgG4 in Pondok Gede, Bekasi district, West Java. The study showed that there was an increase in anti-filarial IgG4 against residence status (p=0.017) and a positive correlation between the number of anti-filarial IgG4 with length of stay in years (p=0.003).

The Role of HIF-1alpha in Regional Lymph Nodes Metastasis in Colorectal Adenocarcinoma Ladyna Rumapar; Sjahjenny Mustokoweni; Alphania Rahniayu
Folia Medica Indonesiana Vol. 54 No. 1 (2018): March
Publisher : Faculty of Medicine, Universitas Airlangga

Colorectal carcinoma has high morbidity and mortality rate worldwide, in which over 90% are adenocarcinoma. Colorectal carcinoma is one of the most cancer that metastasize to the lymph node. Angiogenesis have an important role in tumor growth and metastasis. Hypoxia is the trigger factor for angiogenesis. Hypoxia induced factor-1 (HIF-1) is one critical protein directly reacting to hypoxia. HIF-1alpha, a HIF-1 subunit, is an important regulator of angiogenesis. This study analyzed HIF-1a expression in colorectal adenocarcinoma with and without regional lymph node metastasis. This study was to prove that HIF-1a has a role in regional lymph node metastasis in colorectal adenocarcinoma. An analytical observational study was conducted on thirty formalin fixed paraffin-embedded colorectal adenocarcinoma tissues from Anatomic Pathology Laboratory of Dr. Soetomo Hospital. Detection of HIF-1alpha expressions were performed with immunohistochemistry method, using HIF-1alpha antibody. It were statistically analyzed using Mann-Whitney and Kruskal- Wallis methods. There were no significant differences in the expression of HIF-1alpha in colorectal adenocarcinoma with or without lymph node (LN) metastasis (p>0.05). As a conclusion, this study showed that HIF-1alpha has no role in LN metastasis in colorectal adenocarcinoma.

IMPLEMENTATION ON STIMULATION, DETECTION, AND EARLY INTERVENTION OF CHILD GROWTH AND DEVELOPMENT (SDIDTK) PROGRAM IN PUSKESMAS MOJO, SURABAYA STILL EMPHASIZE ON GROWTH SCREENING Susanti, Dwi; Sustini, Florentina
Folia Medica Indonesiana Vol. 52 No. 1 (2016): JANUARY - MARCH 2016
Publisher : Universitas Airlangga

It's Important to conduct child development screening regularly in primary health services, so child developmental delay cases can be detected and treated as early as possible. Child development screening program in Puskesmas should been carried out integrated with growth screening in Stimulation, Detection, and Early Intervention of Child Growth and Development (SDIDTK) Program. Aims of this study was to gathering informations about the implementation of child development screening activity conducted by Puskesmas Mojo. This was a cross sectional study with kualitatif method. Primary data taken from under 5 years old child's mothers, kindergarten teachers, cadres, and health staff of Puskesmas Mojo. Secondary data gotten from PWS KIA report of Puskesmas Mojo.Results of SDIDTK activities in Puskesmas Mojo according to PWS KIA report, achieve 88.1% in 2013 and 95.2% in 2014. Child development screening activities done infrequenly in Posyandu. Routine activities of Posyandu was growth/nutrition screening. Child development screening activities done by visiting kindergarten school every 6 month but not every child getting development screen, only those who suspicious have developmental delay because of minimum number of staff and aids. Results of SDIDTK activities in Puskesmas Mojo only represents child growth screening activities.

Case Report: ENDOVASCULAR STENTING IN PERIPHERAL ARTERIAL DISEASE OF LOWER EXTREMITY Oktaviono, Yudi Her
Folia Medica Indonesiana Vol. 52 No. 2 (2016): APRIL - JUNE 2016
Publisher : Universitas Airlangga

Peripheral arterial disease (PAD) is usually caused by multilevel atherosclerotic disease, typically in patients with a history of cigarette smoking, diabetes mellitus, or both. Intermittent claudication (IC), an early manifestation of PAD, commonly leads to reduced quality of life for patients who are limited in their ambulation. Percutaneous intervention for peripheral artery disease has evolved from balloon angioplasty for simple focal lesions to multimodality techniques that enable treatment of severe arterial insufficiency. Especially for high-grade stenoses or short arterial occlusions, percutaneous transluminal angioplasty (PTA) should be the method of first choice followed by the best surgical procedure later on. To achieve good long-term efficacy, a close follow-up including objective tests of both the arterial lesion and hemodynamic status, surveillance of secondary preventive measures and risk factor control is mandatory.

THE EFFECT OF ADMINISTERING MANGOSTEEN RIND EXTRACT (Garnicia mangostana l) COMPARED WITH GLIMEPIRIDE TO THE BLOOD SUGAR LEVELS OF WHITE MALE RAT (Rattus norwegicus l) INDUCED BY STREPTOZOTOCIN As'ari, Hasyim; Mahartini, Dewi Mutmainnah
Folia Medica Indonesiana Vol. 52 No. 4 (2016): OCTOBER - DECEMBER 2016
Publisher : Universitas Airlangga

The purpose of this study is to prove the differential effect of administering the mangosteen Rind extract due to lowering the blood sugar levels of Winstar white male rats induced by streptozotosin (STZ). This study used a randomized design of the ramdomized posttest only control group design. The sample consisted of 4 groups with a sample size of 7 animals each group of rats. All samples were prepared STZ induction of diabetes with a single dose of 50 mg/Kg BW through intraperitoneal (IP). K0 (control group; given 1% CMC 1 cc/day), K1 (treatment group 1; given 0,054 mg glimepiride/200 grBW, K2 (treatment group 2; given mangosteen Rind extract 50 mg/Kg BW), K3 (treatment group 3; given the mangosteen Rind extract 100 mg/Kg BW). Timing of therapy in each group was for 7 days. Shapiro-Wilk normality test (a=0.05) in the BW D variable data, pre-post STZ GDP and D GDP. Testing homogeneity used Levene's test. When data distribution was normal and homogenous, it used an ANOVA deferential test. When data distribution was normal and inhomogeneous, it proceed to apply T-test with 2 free samples. The results: 1) There were significant differences between K0 D GDP with K1 (p=0.015), K0 to K2 (p=0.003) and group K0 to K3 (p=0.002), 2) Whereas no difference was shown in the K1 with K2 (p=0.442), K1 to K3 (p=0,401) and K2 to K3 (p=0.878). Conclusion: The administration of mangosteen Rind extract doses of 50 and 100 mg/kg bw/day did not differ in lowering blood sugar levels compared with glimepiride administration of a dose of 0.054 mg/200 grBW rat/day. Mangosteen Rind extract dose of 100 mg/kg bw/day and 50 mg/kg bw/day did not provide a significant difference in lowering blood sugar levels.

EFFECT OF DEACETYLATION DEGREES VARIATION ON CHITOSAN NERVE CONDUIT FOR PERIPHERAL NERVE REGENERATION Qulub, Fitriyatul; Widiyanti, Prihartini; Maulida, Hendita Nur; Indrio, Ludita Woro; Wijayanti, Tia Rahayu
Folia Medica Indonesiana Vol. 53 No. 2 (2017): JUNE 2017
Publisher : Universitas Airlangga

Broken nerves could regenerate when exposed to simple injuries by using a nerve conduit that has appropriate physiological and mechanical ability to support the nerves regeneration around the fissure of trauma. One of the biopolymer for the conduit composition is chitosan because it is biocompatible, biodegradable, non-toxic, and has similarity structure as natural glycosaminoglycans. The aim of research is to synthesize chitosan with variation of Degrees of Deacetylation (DD) and characterize the DD influence on mechanical properties and biocompatibility. Research design is prospective observational. Chitosan was treated with a decrease in the DD method and an increase in the temperature with the strength of alkaline solution, which was NaOH solution with concentrations of 5%, 20%, 35%, and 50% within 2 hours with a heating temperature of 95°C. The results of each DD variation were 23.24, 46.55, 53.48, and 55.06. It was characterized by tensile test with tensile strength values of 0.25 - 1.18 MPa. The degradation test results tend to decrease with the increasing concentration of NaOH proving that samples are biodegradable. The surface morphology of samples shows a pore range of 61.52 Î¼m - 220.3 Î¼m. The best result is the chitosan sample with 35% NaOH because due to the tensile characteristic and a pore in accordance with normal standard. Tensile strength is around 0.41 MPa - 3.69 MPa and pore size around 40 Î¼m – 250 Î¼m to accelerate nerve regeneration. The results are expected to provide alternative solution of nerve conduit development for peripheral nerve defects.

THE EFFECT OF RECOMBINANT VASCULAR ENDOTHELIAL GROWTH FACTOR 121 ON NITRIDE OXIDE LEVEL IN MICE (Mus musculus) MODEL OF PREECLAMPSIA Soetrisno, Soetrisno; Isharyadi, Isharyadi; Sulistyowati, Sri
Folia Medica Indonesiana Vol. 53 No. 3 (2017): September 2017
Publisher : Universitas Airlangga

Preeclampsia is a multifactorial syndrome in pregnancy whose cause is still unknown. Several proangiogenic and antiangiogenic mediators such as Vascular Endothelial Growth Factor (VEGF) and Nitrite Oxide (NO) play important roles in preventing preeclampsia. VEGF can increase NO level that lowers maternal blood pressure, improves endothelial function and reduces placental hypoxia in preeclampsia. Recombinant VEGF 121 is expected to be an option in the prevention and treatment of preeclampsia. This experimental study used mice (Mus musculus) as the model. The objective of this study was to observe the effect of recombinant VEGF 121 in increasing the level of nitric oxide in mice (Mus musculus) model of preeclampsia. This was an experimental analytical study with Randomized Control Trial (RCT) design. The study enrolled 27 pregnant mice (Mus musculus) which met the restriction criteria divided into 3 groups. The first group (K1) were 9 normal pregnant mice. The second group (K2) were 9 pregnant mice of preeclampsia model without treatment. The third group (K3) were 9 pregnant mice of preeclampsia model receiving recombinant VEGF 121 therapy. The independent variable was the administration of recombinant VEGF 121 and the dependent variable was the serum NO level. Statistical analysis was performed by using anova statistics. NO level in the first group (K1) was 1.746±0.347, with minimum value of 1.00 µM, and maximum value of 2.28 µM, CI (1.479-2.013). NO level in second group (K2) was 1.167±0.380, with minimum value of 0.64 µM, and maximum value of 1.94 µM, CI (0.875-1.460). NO level in the third group (K3) was 2.164±0.556, with minimum value of 1.56 µM, and maximum value of 5.96 µM, CI (1.842-2.486). With anova statistical test, there were significant differences between K1 group and K2 group (p value=0.004<0.05), K1 group and K3 group (p value=0.000<0.05) as well as K2 group and K3 group (p value=0.029<0.05). In conclusion, Recombinant VEGF 121 increased the level of nitric oxide in mice (Mus musculus) model of preeclampsia significantly.

EFFECTS OF BLUE LIGHT EMITTING DIODE (LED) AND DOXYCYCLINE TO SEBACEOUS GLAND IN ACNE VULGARIS M Yulianto Listiawan; Cita Rosita Sigit Prakoeswa; Dhyah Aksarani Handamari; Regitta Indira
Folia Medica Indonesiana Vol. 53 No. 4 (2017): December 2017
Publisher : Faculty of Medicine, Universitas Airlangga

Acne vulgaris (AV) is an inflammation of pilosebaceous unit especially in young adult. The pathophysiology is the elevation of sebum production, keratinization of abnormal pilocebaseous follicles, and inflammation caused by immune response to Propionibacterium acnes. Therapy combination of oral antibiotics (doxycycline) and physical therapy (blue light) in moderate-severe acne is one option to reduce antibiotic resistance. Doxycycline is a commonly antibiotic used. The effects of photosensitive can increase the penetration of blue light by sebaceous glands. There was a total decrease in sebum and clinical improvement of combination therapy of blue light and doxycycline in seven patients. The combination therapy has been shown to improve its therapeutic effect, but more clinical trials are needed to prove the effectiveness of blue light with doxycycline than without blue light.

Enhanced Efficacy of Sublingual Immunotherapy in Childhood Allergic Asthma by Probiotics Anang Endaryanto; Mira Irmawati
Folia Medica Indonesiana Vol. 54 No. 1 (2018): March
Publisher : Faculty of Medicine, Universitas Airlangga

It is expected that probiotics may act synergistically to improve the clinical efficacy of sublingual immunotherapy (SLIT). The aim of this study was to investigate the role of probiotics in enhancing efficacy of sublingual immunotherapy in childhood allergic asthma. This was a randomized single blind clinical trial conducted on 6-17 year-old asthmatic children sensitive to house dust mite allergens. Subjects were allocated to Group A receiving SLIT, Group B receiving probiotics and SLIT, Group C receiving probiotics only. Clinical parameters (FEV1 reversibility, medication score, and symptom score) and immunological parameters (total IgE, eosinophil count, IFN-γ, IL-2, IL-4, IL5, IL10, and TGF-b were evaluated in week 0 until 14. Statistical analysis revealed that the difference of clinical parameters (FEV1 reversibility, medication score, and symptom score) between groups were not significant. The difference of the immunological parameters of total IgE, IFN-γ, IL-2, IL-4, IL5, IL10, and TGF-ß were also not significant. Eosinophil count decreased in subjects who received combination SLIT with probiotics. In conclusion, probiotics enhanced the efficacy of sublingual immunotherapy in childhood allergic asthma by decreasing the eosinophil count.

ROLE OF HEPATITIS B AND HEPATITS C VIRUS COINFECTION IN TB DEVELOPMENT Lestari, Pudji; Rahmatullah, Ivan; Susanti, Dwi
Folia Medica Indonesiana Vol. 52 No. 1 (2016): JANUARY - MARCH 2016
Publisher : Universitas Airlangga

Tuberculosis developed differently in each individual. The role of HIV in the disease development is widely known unlike the role of Hepatitis B and Hepatitis C infection. Therefore, this study is aimed at to describe the role of those co-infections in the TB development. The study employed observational – case control design with two groups, case and control group. Data collection include TB condition, whether latent or manifest, and history of Hepatitis B and Hepatitis C co-infection. The study successfully recruited the total of 32 respondents in each group. At the case group, the number of male and respondent is 19 and 13. Meanwhile, at the control group the number male respondent is 10 and the female respondent is 22. The study found that 20 and 12 respondents were positive Hepatitis B at the case and the control group. Chi-square test resulted significant different between two groups (P=0.0455 and a =0.05) with odd ratio p=0.479. Meanwhile, the study only tested one respondent with positive Hepatitis C at case group and one at control group. Comparison analysis found no significant different between groups (P=1 and a =0.05). This study reveals that TB patients are more likely to have history of Hepatitis B 2.7 times than those at the control group with the same infection but without TB development. Therefore, the possibility of Hepatitis B co-infection has role in the TB manifestation, but not for Hepatitis C co-infection.

Page 6 of 55 | Total Record : 547

4 5 6 7 8

Filter by Year

2015 2025

Filter By Issues

All Issue ON PROGRESS Vol. 60 No. 4 (2024): December Vol. 60 No. 3 (2024): September Vol. 60 No. 2 (2024): June Vol. 60 No. 1 (2024): March Vol. 59 No. 4 (2023): December Vol. 59 No. 3 (2023): September Vol. 59 No. 2 (2023): June Vol. 59 No. 1 (2023): March Vol. 58 No. 4 (2022): December Vol. 58 No. 3 (2022): September Vol. 58 No. 2 (2022): June Vol. 58 No. 1 (2022): March Vol. 57 No. 4 (2021): December Vol. 57 No. 3 (2021): September Vol. 57 No. 2 (2021): June Vol. 57 No. 1 (2021): March Vol. 56 No. 4 (2020): December Vol. 56 No. 3 (2020): September Vol. 56 No. 2 (2020): June Vol 56, No 1 (2020): March Vol. 56 No. 1 (2020): March Vol. 55 No. 4 (2019): December Vol. 55 No. 3 (2019): September Vol. 55 No. 2 (2019): June Vol 55, No 1 (2019): March Vol. 55 No. 1 (2019): March Vol. 54 No. 4 (2018): December Vol. 54 No. 3 (2018): September Vol. 54 No. 2 (2018): June Vol. 54 No. 1 (2018): March Vol. 53 No. 4 (2017): December 2017 Vol. 53 No. 3 (2017): September 2017 Vol. 53 No. 2 (2017): JUNE 2017 Vol. 53 No. 1 (2017): JANUARY - MARCH 2017 Vol. 52 No. 4 (2016): OCTOBER - DECEMBER 2016 Vol. 52 No. 3 (2016): JULY - SEPTEMBER 2016 Vol. 52 No. 2 (2016): APRIL - JUNE 2016 Vol. 52 No. 1 (2016): JANUARY - MARCH 2016 Vol. 51 No. 4 (2015): Oktober - December 2015 Vol. 51 No. 3 (2015): July - September 2015 More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota surabaya,

Jawa timur

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

Contact Email -

Phone -

Journal Mail Official -

Editorial Address -

Location Kota surabaya, Jawa timur INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota surabaya,

Jawa timur

INDONESIA