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Jurnal Biosains Pascasarjana
Published by Universitas Airlangga
ISSN : 14121433     EISSN : 26214849     DOI : http://dx.doi.org/10.20473/jbp.v22i1.2020.1-10
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology
Jurnal Biosains Pascasarjana is published not only for the publication of research results from graduates, as one of the graduation requirements but also for public that contains a discussion of the natural content, responses of living things, and their environment.
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 199 Documents
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EFFECT OF DIFFERENCES BROMELAIN ENZYME CONSENTRATION ON PROTEIN HYDROLYSATE FROM WASTE OF TILAPIA VISCERA (Oreochromis sp.) ON ANTIOXIDANT ACTIVITY Muhammad Athoillah Sholahuddin; Lastuti, Nunuk Dyah Retno; Amin, Muhamad
Jurnal Biosains Pascasarjana Vol. 26 No. 1 (2024): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v26i1.2024.15-22

Abstract

Tilapia is a commodity that is widely consumed by the public, especially in Indonesia. Fresh tilapia offal has a protein content composition of 55.55%, so to increase its selling value it is often made into protein hydrolysate. Protein hydrolysis using enzymes is an effective way, because it can make protein hydrolysates avoid damage to certain amino acids. Proteolytic enzymes have many types and one that can be used as a hydrolyzer, in producing protein hydrolysates is bromelain enzyme. The purpose of this study was to determine the effect of proteolytic enzyme type and hydrolysis time on antioxidant activity of protein hydrolysate from Oreochromis sp. offal waste. This study used RAL 2 factors and each was repeated 3 times. The first factor was the concentration of bromelain enzyme used, namely control concentration, 1%, 2% and 3%. The second factor was the hydrolysis time, which was 4 hours, 6 hours and 8 hours. The data obtained were analyzed and continued with antioxidant activity test, hydrolysis degree test and protein content test. The best concentration of bromelain enzyme as antioxidant was 3% concentration for 6 hours hydrolysis with IC50 value of 82.53µg/mL, the best DH of 82.25%±4.03 and the highest protein content of 54.55%. Keywords: Antioxidant, bromelain enzyme, tilapia offal, protein hydrolysate
LOTION PROTECTIVE EFFECT USING LEMONGRASS ESSENTIAL OIL (Cymbopogon citratus) AGAINST Aedes aegypti Ainun Sida; Ni Luh Arpiwi; Anak Agung Ketut Darmadi
Jurnal Biosains Pascasarjana Vol. 25 No. 2 (2023): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v25i2.2023.146-155

Abstract

Lemongrass consists of two types that have many benefits. Its use in research or in processing using its stems alone causes lemongrass leaf waste which can be used as an essential oil and used as an anti-mosquito lotion to reduce the use of chemicals as repellent. The purpose of this study was to determine the yield of lemongrass essential oil, to determine the protective power of each concentration of citronella essential oil in lotion in repelling mosquito bites, and to determine the level of preference for mosquito repellent lotion. The average yield with three repetitions followed by standard deviation (SD) was 0.1% ± 0.0024% b/b. Lotion preparation provides different protection during 6 hours of exposure, namely K- and F1 no protection, F2 for 2 hours, F3 and K+ 4 hours and F4 5 hours. Based on all parameters, the most preferred formulation is F1 and does not give sensitive reactions. Keyword: Aedes aegypti, essential oils, lemongrass, lotions.
TEICHMANN TEST: ASSESSMENT OF HEMOGLOBIN CRYSTALS ON BLOOD SPOTS EXPOSED TO POWDER DETERGENT Abid, Istiana Firqah; Rezakola, Erik; Hanura, Imam Yusuf
Jurnal Biosains Pascasarjana Vol. 26 No. 1 (2024): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v26i1.2024.23-27

Abstract

Evidence found at the crime scene (TKP) in the form of bloodstains needs to be examined to ensure that the evidence is really blood so that it can assist the investigation process. However, in some cases, criminals can remove or remove bloodstains using detergents that are used daily which contain surfactants. The purpose of this study was to find out how to examine and describe hemoglobin crystals in blood spots exposed to several powder detergents using the Teichmann test. This study used an experimental method using 3 different brands of detergent with 2 controls, namely a positive control with the presence of blood spots and a negative control without blood spots. The examination results obtained positive control results in all experiments as much as 100% still giving a brown rhombus-shaped appearance of hemoglobin crystals like needles even though the blood spots had been exposed to powder detergent. Keywords: Blood spot, Detergent, Hemoglobin, Teichmann test
D-DIMER AS A PROGNOSIS OF THE SEVERITY OF COVID-19 PATIENTS AT BEKASI REGENCY HOSPITAL Kurniawati, Dyah Eka
Jurnal Biosains Pascasarjana Vol. 26 No. 1 (2024): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v26i1.2024.28-37

Abstract

The increase in D-dimer is the most significant change in coagulation parameters in Covid-19 patients and can be a marker of poor prognosis.  The purpose of this study was to see the average significant D-dimer levels in patients with confirmed Covid-19 with severity. The method used is Retrospective Research with a purposive sampling technique based on the criteria of the severity of Covid-19 disease. Patient data was taken from medical records and D-dimer levels from the Laboratory Information System and then analyzed using a one-way Anova test. The results showed an average D-dimer level of 2.66 mg/L at critical degrees, 2.02 mg/L at severe degrees, 0.30 at moderate degrees and 0.26 at mild degrees. Male patients occupy a larger percentage than female patients with a total of 62.5%. The age of 46-65 years occupies the highest percentage of 55% for the abnormal category because the immune system as a protector of the body does not work as strongly as when it was young. This study showed a significant average difference in the groups of mild severity with severe, mild with critical, moderate with severe, and moderate with critical. For the next researcher, it is expected to be able to analyze other hemostasis examination parameters with variables of disease severity. Kata kunci: Coronavirus, COVID-19, D-dimer, parameter koagulasi, pembekuan darah
EFFECT OF HIGH-FAT DIET ON SERUM TNF-ALPHA LEVELS, A MARKER OF LOW-GRADE INFLAMMATION Cut Indriputri
Jurnal Biosains Pascasarjana Vol. 26 No. 1 (2024): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v26i1.2024.38-51

Abstract

A high-fat diet is a pattern of excessive fat consumption that can cause various metabolic function disorders, such as hypertension, dyslipidemia, obesity, and increased glucose levels. The aim of this study was to analyze the effect of a high-fat diet on serum tumor necrosis factor alpha (TNF-α) levels as a marker of low-grade inflammation in Wistar rats. The study was designed using a true experimental randomized posttest-only control group. Sixteen male Wistar rats weighing 150-250g and aged 4-5 months were divided into two groups. Group K1 was a negative control group that was given normal diet, while group K2 was a group that was given a high-fat diet, with a fat content of 66.28%. This treatment was controlled for 50 days. The mean TNF-α levels in K1 (290.912 ± 1.87) pg/mL and K2 (295.149 ± 2.76) pg/mL. Based on the results of independent T-test analysis, TNF-α levels in groups K1 and K2 were significantly different (P = 0.034 or P < 0.05). This means that a high-fat diet increases serum levels of TNF-a, a marker of low-grade inflammation.
SKELETON ANALYSIS OF Tursiops truncatus REGIO COSTAE AND SCAPULA STRANDED ON SENGGIGI BEACH, WEST LOMBOK Qodri, Hasby faizul; Rahmawati, Septyana Eka; Riwu, Katty Hedriana Priscilia; Barmawi, Muhammad; Kholik
Jurnal Biosains Pascasarjana Vol. 26 No. 1 (2024): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v26i1.2024.52-63

Abstract

The dolphin (Tursiops truncatus) is the most studied and most common species of cetacean in captivity. In this study, the size results obtained were the ribs and scapula. The first measure is a difference from the proximal to the distal end between the literature and this study. the second and third sizes have long, short, and longer proximal to distal differences. The fourth, fifth and sixth sizes show that the bones of T.truncatus are smaller than those of the Numataphocoena yamashitai species and the seventh size shows that the differences between T.truncatus and the Numataphocoena yamashitai species are several short and long costae. For the scapula, the dimensions of the first and second bones are larger than the present study species T.truncatus and Numataphocoena yamashitai. The sizes of the three results from this study are almost the same as the species Numataphocoena yamashitai except for the species Prosqualodon marplesi, which is larger than this study and research in California. The fourth size, which is 49.0 mm from head to tuberculum, is larger than the species T.truncatus and Numataphocoena yamashitai studied. The fifth size, the diameter of the rib head of this research species is smaller than the species Numataphocoena yamashitai and Prosqualodon marplesi, both of which are smaller than T.truncatus, and some of these differences are caused by food, habitat and environmental conditions.  
NURSING INTERVENTION GIVING WARM COMPRESS TO LARGE VEINS AREAS WITH ABDOMEN WALLS TO DECREASE TEMPERATURE OF HYPERTHERMIC PATIENTS Handayani, Risanti; Hariyono; Hargono, Arief
Jurnal Biosains Pascasarjana Vol. 26 No. 1 (2024): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v26i1.2024.64-71

Abstract

Intra-abdominal organs are receptors that are more sensitive to temperature, cold. While the large vein area is effective because of the vasodilation process by giving warm compresses to reduce body temperature on the body surface. The purpose of this study was to determine the effectiveness of giving warm compresses to the abdominal wall (abdomen) and large vein (axilla) area to decrease the body temperature in fever patients. The design of this research is Quast-Experiment, Design with Nonequivalent Control Group Design approach. The population of this study was all patients with fever as many as 26 respondents. Samples were taken by consecutive sampling technique as many as 20 patients. The research variable is a warm compress in the axilla and abdomen and the independent variable is a decrease in body temperature. Data were collected by observing body temperature and analyzed by using the T-test. The results showed that abdominal compresses were more effective because the number of patients who did not experience a decrease was 1 respondent, while the axilla compression had 2 respondents. The results of the normality test of the data showed that the data were not normally distributed so that the hypothesis testing used the T-test and the results showed that the data was p = 0.000, = 0.05 so that p < a means Ho is rejected, meaning that the difference in body temperature decrease between giving axillary compresses and abdominal compresses is not too significant. and not that much different. Keywords: Warm Compress, Fever, Body Temperature.
DIFFERENCES IN INTERFERON GAMMA LEVELS IN TREATMENT OF TUBERCULOSIS IN INTENSIVE PHASE AND ADVANCED PHASE Kuncara, Rachmad Bayu; SY. Didik Widiyanto; Ririh Jatmi Wikandari; Wiwit Sulistyasmi
Jurnal Biosains Pascasarjana Vol. 26 No. 1 (2024): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v26i1.2024.72-76

Abstract

Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis complex (MTBC). Anti-tuberculosis drugs given to active TB sufferers consist of 3 or 4 combinations. Tuberculosis treatment is divided into intensive phase treatment (2 weeks) and continuation phase (16 weeks / 4 months). Interferon gamma (IFN γ) is a protein belonging to the cytokine family which plays a role in eliminating MTB bacteria through a cell-mediated immunity mechanism. The aim of this study was to analyze differences in gamma interferon levels in the intensive phase and advanced phase of tuberculosis treatment. This research method is an analytical observational study with a cross-sectional design (cross sectional study). The research design used was a randomized post test only control group design. Data were analyzed using the Kruskal Wallis test with statistical test results obtained with a p value of 0.033 (> 0.05), meaning there was a difference in IFN γ levels in the intensive phase and advanced phase of tuberculosis treatment.
DNA TOUCH STR CODIS AS LEGITIMATE EVIDENCE IN UNCOVERING CRIMINAL ACTS Nurdianto, Arif Rahman; Setiawan, Fery; Yudianto, Ahmad; Nurdianto, Rizal Fauzi; Sunariani, Jenny
Jurnal Biosains Pascasarjana Vol. 26 No. 1 (2024): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v26i1.2024.77-86

Abstract

The identification process at the crime scene (TKP) is one of the essential tasks carried out by police investigators. One critical aspect is the collection and analysis of evidence found at the crime scene, referred to as biological evidence (BB). This evidence serves as a crucial source for determining whether an incident occurred and, if so, whether it was a suicide or another criminal act (such as murder, etc.). The biological evidence found can be analyzed using molecular serobiology approaches, which are rapidly advancing in the fields of forensic medicine and medicolegal practice. One such approach involves utilizing DNA traces, although a common challenge is that often the DNA recovered at crime scenes is degraded. Therefore, a DNA amplification method utilizing the Polymerase Chain Reaction (PCR) technique, along with the short tandem repeat (STR) – CODIS identification approach, is necessary. The analysis of DNA traces using the STR-CODIS approach enables investigators to determine whether the incident was purely criminal, a suicide, or another type of accident involving the victim. Furthermore, the DNA analysis using the STR-CODIS method can also aid in identifying the victims discovered at the crime scene.
BRAIN IMAGING OF PSYCHOPATHY: A NARRATIVE LITERATURE REVIEW Angkawidjaja, Katharina Merry Apriliani; Suryadinata, Rivan Virlando
Jurnal Biosains Pascasarjana Vol. 26 No. 2 (2024): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v26i2.2024.133-142

Abstract

The general definition of psychopathic is an individual who focuses on self-perspective, is feelingless, without compassion, lacks empathy, lacks/disloyalty, and lacks the ability to form close relationships (less intimacy). Psychopathy is also known as psychopathic, antisocial, disocial, and sociopathic personality disorder. In Indonesia, clinical diagnosis guidelines for psychopathic individuals still refer to Dissocial Personality Disorder according to the Guidelines for Classification and Diagnosis of Mental Disorders Edition III (PPDGJ-III), coupled with other commonly used supporting examinations, namely the MMPI (Minnesota Multiphasic Personality Inventory), LSRP (Levensone Self-Report Psychopathy Scales), PCL:SV (Psychopathy Checklist: Screening Version). This Narrative Literature Review aims to summarize findings about brain imaging in Psychopath. As for psychopathic-related brain imaging, namely aberrant brain activity was found in the prefrontal area, temporal cortex, limbic (amygdala- hippocampus complex), striatum, corpus callosum, and insular. These findings hope to be able to explain the basic etiological of deviant behavior in psychopathic perpetrators. Thus, psychopathic neuroanatomy is a research area that has the potential to contribute as a preventive and curative measure of psychopathy on a scientific basis.

Page 17 of 20 | Total Record : 199

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