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Suryani Dyah Astuti
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Jurnal Biosains Pascasarjana
Published by Universitas Airlangga
ISSN : 14121433     EISSN : 26214849     DOI : http://dx.doi.org/10.20473/jbp.v22i1.2020.1-10
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology
Jurnal Biosains Pascasarjana is published not only for the publication of research results from graduates, as one of the graduation requirements but also for public that contains a discussion of the natural content, responses of living things, and their environment.
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 199 Documents
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A REVIEW: EXPERIMENTAL ANIMAL MODEL OF HELICOBACTER PYLORI IN 2018-2023 Cheardi, Natallensi Deara
Jurnal Biosains Pascasarjana Vol. 27 No. 1 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i1.2025.49-64

Abstract

H. pylori is a Gram-negative bacterium that has colonized the stomachs of approximately 50% of the human population worldwide. H. pylori is a major pathogen associated with gastrointestinal diseases, including gastritis, peptic ulcers, and gastritis, gastric adenocarcinoma, and mucosa-associated lymphoid tissue (MALT). To study the pathogenesis, prevention and therapy of H. pylori infection, ideal, safe and stable animal model experiments are needed. Therefore, in this text we summarize several important aspects in successfully creating experimental animal models of H. pylori. The method used is literature study through two electronic databases, namely Sciencedirect and Pub Med. A total of 50 articles were used in this study. Full text assessment was carried out according to inclusion and exclusion criteria. The C57BL/6 and BALB/c animal models are capable of producing gastritis, metaplasia and hyperplasia and rarely produce cancer, while Mongolian gerbils and transgenic mice are considered more susceptible to creating cancer models. The strains commonly used in research on H. pylori infection are SS1 and PMSS1 because they are considered to be CagA-positive. The non-invasive method for confirming H. pylori that is most often used in experimental animal models is the ELISA serological test, while the invasive methods that are often used are RUT and H&E and other additional staining.
PHYSICS OF BLOODSTAIN PATTERN ANALYSIS Afdhila, Zakia
Jurnal Biosains Pascasarjana Vol. 27 No. 1 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i1.2025.43-48

Abstract

Bloodstain patterns are one of the pieces of evidence that can be found at the scene. Bloodstain pattern analysis is carried out to help reconstruct the events or occurrences that caused the formation of the pattern. Analysis is based on a combination of physics, biology and mathematics. Factors that influence the formation of bloodstain patterns are: surface tension and viscosity, drag and gravity and their influence on speed, and the shape of bloodstains when falling. In addition, surface conditions can affect the pattern of blood produced. Determining the area of "‹"‹origin of the bloodstain is carried out based on the impact angle calculated from the length and width of the bloodstain pattern. The analysis carried out in the experiment shows that there is closure in the bloodstain pattern analysis due to the assumption of a linear trajectory and determining the angle of the bloodstain. Different impact speeds will produce different bloodstain patterns.
ALTERNATIVE MATRICES FROM THE ORAL CAVITY AS A SOURCE FOR DRUG DETECTION Ambarioni, Agnes; Prayudha, Anggy
Jurnal Biosains Pascasarjana Vol. 27 No. 1 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i1.2025.65-75

Abstract

Forensic toxicology plays a crucial role in law enforcement by detecting xenobiotic substances in the human body, aiding in legal decisions. Traditional matrices like blood and urine have significant drawbacks, such as invasiveness, susceptibility to adulteration, and limited detection windows. This paper explores alternative matrices from the oral cavity, including oral fluid, teeth, dental plaque, and dental calculus, for drug detection. Oral fluid offers non-invasive collection and reliable pharmacokinetic data, while teeth provide long-term drug detection in postmortem cases. Dental plaque and dental calculus can trap substances over time, offering insights into past drug use with less invasive sampling. These matrices reflect the overall condition of the body and provide valuable forensic information. Continued research and technological advancements are necessary to optimize their application in various forensic scenarios.
ANALYSIS OF THE IMPACT OF FOOT-AND-MOUTH DISEASE ON PRODUCTION MANAGEMENT AND BUSINESS FEASIBILITY OF SAPI SONOK IN SUMENEP REGENCY Wulandari, Islami; Sri Hidanah; Soeharsono
Jurnal Biosains Pascasarjana Vol. 27 No. 1 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i1.2025.36-42

Abstract

This study aims to determine the impact of foot and mouth disease (FMD) on production management consisting of maintenance management, cage management, health management, feed management and business analysis of sonok cattle in Potre Koning Sonok Cattle Association in Lenteng Sub-district, Sumenep District. This study used 21 respondents consisting of 20 association members and one paramedic. The primary and secondary data were obtained from the distribution of questionnaires and interviews. Questionnaire data are divided into three groups: before FMD, during FMD, and post-FMD, which were then analyzed using the Manova test and the Duncan test. The results showed significant differences in housing management, health management, feed management, and business analysis (p<0.05). Housing management showed no significant difference in the time before, during and after FMD, while business analysis during FMD suffered losses due to decreased productivity of sonok cattle. Health management is the most influential management during FMD. Farmers ignore the profitability of raising sonok cattle because sonok cattle are a hobby for farmers.
ANALYSIS OF REPRODUCTIVITY OF MADRASIN CATTLE BEFORE AND AFTER FOOT AND MOUTH DISEASE ON GILI IYANG ISLAND, SUMENEP, MADURA Zulfah; Sabdoningrum, Emy Koestanti; Hidanah, Sri; Lokapirnasari, Widya Paramita; Mufasirin; Yudanianyi, Ira Sari
Jurnal Biosains Pascasarjana Vol. 27 No. 1 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i1.2025.32-35

Abstract

This research aims to analyze reproductivity (S/C and Pregnancy) and supply and demand for Madrasin cattle before and after FMD disease on Gili Iyang Island, Sumenep, Madura. This research used data from 450 madrasin cattle on Gili Iyang Island, Sumenep. The research was carried out by comparing data obtained before the FMD outbreak in January 2022 – May 2022 and after the FMD outbreak in June 2022 – November 2022. The results of the research showed that the reproductivity of Madrasin cattle before and after the FMD disease on Gili Iyang Island, Sumenep, Madura in S/C increased, while during pregnancy there is a decrease. The supply and demand for the Madrasin cattle business before and after the FMD on Gili Iyang Island, Sumenep, Madura, decreased.
THE EFFECT OF LED MAGNETIC ON STAPHYLOCOCCUS AUREUS BACTERIA Yonatan; Astuti, Suryani Dyah; Ain, Khusnul; Arifianto, Deni; Yaqubi, Ahmad Khalil
Jurnal Biosains Pascasarjana Vol. 27 No. 1 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i1.2025.25-31

Abstract

Nosocomial infections, caused by viruses, bacteria, and fungal pathogens, often occur during treatment in health facilities due to cross-contamination from healthcare workers or medical equipment. The study explores the efficacy of static magnetic fields and photodynamic inactivation in inactivating Staphylococcus aureus bacteria, a crucial step in sterilization. The study used high-power blue LEDs and static magnetic fields generated by neodymium magnets. The highest reduction percentage observed was 81.92 ± 7.92%, found in the combination treatment of static magnetic fields (SMF) with LED illumination at the F8 microplate location, with a treatment time of 40 minutes, an LED dose of 11.72 J/cm², and a magnetic field dose of 25.61 mT. The lowest reduction percentage, 52.41 ± 7.64%, was observed at the F8 microplate location with a treatment time of 10 minutes, an LED dose of 2.93 J/cm², and a magnetic field dose of 25.61 mT.
DETERMINATION OF DIASTASE ENZYME ACTIVITY AND WATER CONTENT OF HONEY FOREST OF SULA ISLAND, NORTH MALUKU Yasin, Fazrul M.; Afriadi, Denni; Qutni, Iqbal Abdul; Algeri, Ezi Fedila; Karepoan, Maria Alexandra
Jurnal Biosains Pascasarjana Vol. 27 No. 1 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i1.2025.1-4

Abstract

The experiment that has been carried out aims to determine the quality of forest honey originating from the Sula Islands, North Maluku based on the parameters set by the Indonesian National Standards Agency (SNI) 8864:2018, which includes organoleptic parameters (odour and taste), water content and Diastase Number. These parameters can indicate the originality of a forest honey product. The research was conducted at the Forensic Laboratory Center of the Criminal Investigation Department of the Republic of Indonesia Police, using the laboratory experiment method, using the UV-Vis Spectrophotometry instrument, forest honey originating from the Sula Islands district, North Maluku Province was used as material in this experiment. Organoleptic tests including odour and taste were carried out using the sense of smell and taste, water content testing using an oven drying technique, and DN value determination using the UV-Vis Spectrophotometry instrument. The experiment results showed that some parameters met the requirements and did not meet the criteria. Tests on Sula Islands forest honey's taste and water content parameters did not meet the criteria, but the odour and DN parameters met the requirements. Keywords:  Forest honey, honey quality, UV-Vis spectrophotometry
ANTI-INFLAMMATORY POTENTIAL OF FUNGUS COMBS FROM INDO-MALAYAN TERMITE MACROTERMES GILVUS HAGEN MOUND: REVIEW ARTICLE Rahayu, Retno Pudji; Mulyani, Sri Wigati Mardi; Imannia, Ristya Sylva; Caesario, Jefferson; Loverita, Dyta; Nuzulistina, Elvin
Jurnal Biosains Pascasarjana Vol. 27 No. 1 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i1.2025.18-24

Abstract

There is evidence that termite colonies of the subfamily Termitomyces produce an unusual structure called a fungus comb, especially Termite mounds in Indo-Malaysian regions. This comb may include bioactive components that the termites use to investigate if they might aid in the body's inflammatory response. The anti-inflammatory potential, concentration, and bioavailability of fungal comb from the Indo-Malayan termite macrotermes gilvus Hagen mound will be further discussed in this research. We utilized databases to review the current evidence related to anti-inflammatory potential of fungus combs and termite macrotermes gilvus hagen mound. We discussed the most recent evidence of fungus combs and termite macrotermes gilvus mound regarding the anti-inflammatory potential, concentration, and bioavailability. This study concludes that ethyl acetate extract from fungus comb could enhance the immune system. Phenolic compounds have a positive effect on health indicators. These mechanisms may account for the decreased prevalence of chronic degenerative disorders in populations.
REVIEW OF THE USE OF DNA BARCODING IN AVIFAUNA RESEARCH: CONSERVATION, AUTHENTIFICATION, AND DISEASE DETECTION I Wayan Rosiana; Made Pharmawati; I Made Murna; Putu Angga Wiradana; Ni Wayan Ayu Wiartini; Fransiskus Jimmy Roga
Jurnal Biosains Pascasarjana Vol. 27 No. 1 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i1.2025.10-17

Abstract

DNA barcoding is an effective tool for identifying species, with additional uses for measuring molecular diversity, authentication of illegal products, and early detection of disease types. In this review, we discussed the use of DNA barcoding for Avifauna research, that is known to have an important impact on environmental health. The existence of Avifauna is threatened with extinction due to human anthropogenic activities. This review starts by providing a general overview of DNA barcoding, focusing on its application in Avifauna research, metabarcoding, as a tool in detecting food samples from the Avifauna, tracking enandgered and protected exotic birds, and tracking avifauna diseases. This review concludes with definitive statements and challenges regarding the use of DNA barcoding, especially in regions with high levels of avifauna diversity. This review can contribute to a better understanding of DNA barcoding and its potential in managing Avifauna genetic resources in the wild and conservation institutions.
RECENT DEVELOPMENT OF POTENTIAL THERAPY FROM NATURAL COMPOUNDS IN Helicobacter pylori INFECTION: A SYSTEMATIC REVIEW Susanti; Afifudin, Alfin Fatwa M.
Jurnal Biosains Pascasarjana Vol. 27 No. 2 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i2.2025.76-90

Abstract

This work performs a systematic literature review on potential Natural Product in Helicobacter pylori (H. pylori) and discusses the development of potential therapy from various natural resources. A search method was used to locate papers published between 2019 and 2024 in Web of Science and PubMed databases, and 14 studies were selected. Reports on potential Natural Product in H. pylori, in vitro and in vivo study design are included. Articles not written in English or whose full text could not be accessed were excluded. The remaining publications were checked and evaluated to determine whether they contain supportive natural product in H. pylori infection. The majority of articles are used non RCT study design and Minimum Inhibitory Concentration (MIC) was the most commonly utilized parameter in these studies. These studies generally focus on in vitro investigation using natural product such as licorice root extract, C. striata extract, propolis extract, and virgin olive oil extract on the certain strains of H. pylori. Different extracts of natural products were reported to have different particular effects on H. pylori including antimicrobial activity, the regulation of inflammatory cytokines and genes, and the association of protection and histopathology effects.There has been numerous research on potential Natural Product in H. pylori infection, but it is not yet applicable in health practice. In the future, the potential Natural Product studies expected to reach the clinical study stage and to contribute to the invention on the treatment of H. pylori infection.

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