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Journal of Agromedicine and Medical Sciences
Published by Universitas Jember
ISSN : 24609048     EISSN : 27145654     DOI : -
Core Subject : Health,
Jurnal Agromedicine and Medical Sciences (AMS) adalah jurnal berkala empat bulan (Februari, Juni dan Oktober) yang berisi berbagai artikel dalam bentuk penelitian, tinjauan sistematis dan laporan kasus dalam bidang kedokteran dengan fokus pada ilmu-ilmu kedokteran dasar, kedokteran klinis dan agromedis.
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Articles 11 Documents
Search results for , issue "Vol 8 No 2 (2022)" : 11 Documents clear
Effective Dose of Moringa Leaf Extract (Moringa oleifera Lamk.) to Descrease Total Cholesterol Levels in Streptozotocin-Induced Male Wistar Rats Pipiet Wulandari; Athiyah Fi Ramadani; Suryono Suryono; Ali Santosa
Journal of Agromedicine and Medical Sciences Vol 8 No 2 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i2.27402

Abstract

Lipid metabolic disorder in hyperlipidemia characterized by an increase in the entire lipid profile in the blood. In 2019, the global prevalence of hyperlipidemia was 64.2%. Many patients with diabetes mellitus developed to hyperlipidemia. Diabetes mellitus characterized by hyperglycemia that caused by insulin production defects or decreased insulin resistance. Hyperglycemia in this study resulted from the injection of a streptozotocin dose of 45mg/kgBB intraperitoneally. Hyperglycemia could induced hyperlipidemia. It is due to increased lipid synthesis resulting in overproduction of HMG-CoA and ROS. Moringa leaves contain active substances such as flavonoids and vitamin C that act as antioxidants. This study was conducted to find out the effective dose of moringa leaf extract to lower the total cholesterol levels of male Wistar rats induced by streptozotocin. The dose of moringa leaf extract was divided into 5 groups, namely 62.5 mg/kgBW, 125 mg/kgBW, 250 mg/kgBW, 500 mg/kgBW, and 1000 mg/kgBW. The analysis of the data in this study was a Pearson correlation test that showed p< 0.05. It demonstrated that administration of moringa leaf extract correlated with decreased cholesterol levels of male Wistar rats. The effective dose of moringa leaf extract was calculated using a linear regression test. The equation obtained from the regression test was y= 0.0739x + 153.59, so the dose of moringa leaf extract that effectively lowers the total cholesterol levels of male Wistar rats was 528.96 mg/kgBW. Keywords: hyperlipidemia, diabetes mellitus, cholesterol, Moringa oleifera Lamk., streptozotocin
Risk Factors of Postoperative Nausea and Vomiting on General Anesthesia in RSUD Abdul Wahab Sjahranie Samarinda Christopher Kevin Susanto; Eva Rachmi; Muhammad Rizqan Khalidi
Journal of Agromedicine and Medical Sciences Vol 8 No 2 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i2.29227

Abstract

Postoperative Nausea and Vomiting (PONV) is the nauseous feeling within 24 hours after surgery. PONV increases the risk of fluid and electrolyte imbalance, re-opening of the surgical wound, and aspiration of gastric fluid. This study aimed to analyze the effect of postoperative opioid administration, duration of anesthesia, type of surgery, and BMI on the incidence of nausea and vomiting after surgery under general anesthesia, at Abdul Wahab Sjahranie Hospital, Samarinda. The research design employed in this research was a retrospective cohort study. The number of samples was 92 patients. The results of the analysis showed an increased risk of PONV in underweight – normal BMI patients (1.45 times higher risk; p=0.035), patients who received postoperative opioids (1.64 times higher risk; p=0.005), patients who underwent surgery that was potentially stimulating the vagus nerve (1.52 times riskier; p=0.02), and patients with anesthetic duration of more than 2 hours (1.93 times greater risk; p=0.007). Therefore, it could be concluded that BMI, postoperative opioid use, type of surgery, and duration of anesthesia influenced PONV incident on the use of general anesthesia at RSUD Abdul Wahab Sjahranie, Samarinda. Keywords: postoperative nausea and vomiting, BMI, opioid after surgery, type of surgery, anesthesia duration
High Degree of Parasitemia Induces Placental Hypoxia and Low Birth Weight Nurfianti Indriana; Zainabur Rahmah; Alvi Milliana
Journal of Agromedicine and Medical Sciences Vol 8 No 2 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i2.31243

Abstract

Placental malaria causes low fetal weight associated with infiltration of monocytes and parasites in the placenta resulting in placental hypoxia. Hypoxia is characterized by HIF expression. HIF-1α expression responds early to the occurrence of hypoxia (<24 hours) and HIF-2α promotes chronic hypoxia (>24 hours). There were two groups in this study, namely the control group (10 pregnant mice without Plasmodium berghei infection) and the treatment group (10 pregnant mice infected with Plasmodium berghei). Pregnant mice were operated on on the 18th day after mating. The degree of parasitemia was measured by Giemsa staining. Expression of HIF-1α and HIF-2α in placental tissue was measured by immunohistochemistry. Results by paired t test, HIF-1α expression in the placental tissue in the treatment group was higher than the control group (p=0.02), HIF-2α expression in the placental tissue was higher in the treatment group than in the control group (0, 01) the fetal weight in the treatment group was lower than in the control group (p=0.01). By using SEM analysis, the degree of parasitemia caused high expression of HIF-1α in placental tissue (tcount = 4.625, ttable = 1.96). High expression of HIF-2α in placental tissue (tcount = 2.672 ttable = 1.96). The degree of parasitemia causes low fetal weight (tcount = 27.764 ttable = 1.96). The results also showed that HIF-1 caused low birth weight (tcount = 2.376 ttable=1.96) also HIF-2α caused low fetal weight (tcount = 4.267 ≥ 1.96). Conclusions the degree of parasitemia causes high expression of HIF-1α and HIF-2α in placental tissue and low birth fetuses. Expression of HIF-1α and HIF-2 also causes low birth weight. Keywords: malaria in pregnancy, degree of parasitemia, HIF-1α , HIF-2α , birth weight
Comparison of Student Anxiety Levels in Facing CBT Exams Based on Gender Wahyuni Dyah Parmasari; Nauval Hakim; Ayly Soekanto
Journal of Agromedicine and Medical Sciences Vol 8 No 2 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i2.31212

Abstract

Anxiety is assumed to be an unclear feeling, which causes worry, fear of everything that does not necessarily happen. This anxiety has a psychological impact on a person including it can affect learning achievement. Various studies related to anxiety theory state that gender affects the level of anxiety. Women are considered more prone to anxiety than men. In this study, researchers measured men's anxiety degrees compared to women when taking computer-based tests (CBT) during the pandemic. Exams with this method are suspected to be one of the triggers for anxiety in medical students. The purpose of this study was to compare the level of anxiety of students and female students in facing CBT at Wijaya Kusuma University Surabaya during the pandemic. This study used a cross-sectional approach with a total sampling technique. The total number of respondents was 60 people, 16 men and 44 women. Respondents' anxiety degrees were measured by a measurement scale of depression, anxiety, and stress or what is known as the Depression Anxiety and Stress Scale 21 (DASS-21). The results showed that 12.5% of men and 31.8% of women were in the heavy and very heavy group. The conclusion of this study is that the level of anxiety of women is higher than those men. Keywords: anxiety levels, medical students, gender, computer based test exam
The Correlation Between Mother's Knowledge about Complementary Feeding with The Incidence of Stunting in Toddlers Under Two in Mayang, Jember Dwita Aryadina Rachmawati; Ranindya Putri Cipta Indraswari; Elly Nurus Sakinah
Journal of Agromedicine and Medical Sciences Vol 8 No 2 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i2.25606

Abstract

Stunting is a condition of toddlers who have a height-for-age less than -2 SD WHO Z-score. The period from a newborn until two years is also known as the golden period. Nutrition obtained after birth affects the growth and development of them. Complementary feeding was given when they were 6 months old. The level of mother's knowledge about complementary foods has an impact on complementary feeding. Inappropriate complementary feeding can lead to stunting. The research objective was to determine the correlation between mother's knowledge about complementary feeding and the incidence of stunting in toddlers under two in Mayang. The research was an analytical observational with a cross sectional study design. The sample was 90 respondents taken using consecutive sampling method. Data collection using a questionnaire on the mother and using height-for-age data from the toddlers. Statistical test using the Spearman test, showed that there was a significant correlation between the level of mother's knowledge about complementary feeding and the incidence of stunting (p=0.024.; rho=-0.238). Due to this result, we recommend continuous health promotion and education among mothers to decrease the risk of stunting in their children. Keywords: stunting, complementary feeding, toddlers under two, mother’s knowledge
Symptoms Improvement of Cerebral Venous Sinus Thrombosis: A Case Report Komang Yunita Wiryaning Putri; Novan Krisno Adji; Azham Purwandhono; Muhammad Yudha Nugraha; Salsabila Maula Zalfa El Hamzah
Journal of Agromedicine and Medical Sciences Vol 8 No 2 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i2.30193

Abstract

Cerebral venous sinus thrombosis (CVT) is a rare cause of stroke, a life-threatening disorder that occurs in approximately 0,5-1% of all stroke incidents. Various clinical presentations, risk factors, and neuroimaging findings of this disease may cause a delay in the early diagnosis and treatment of CVT. We discuss a case of a 34-year-old female who was admitted to the emergency room (ER) with the onset of a generalized tonic-clonic seizure with a progressive headache in the occipitotemporal region. Based on head CT, there was multiple hyperdense and cerebral venous infarction in the posterior left parietal lobe. D-dimer evaluation, there was an increasing level of D-dimer (>10.000 ng/mL). The patient was treated with the primary therapy heparin. After 15 days of being hospitalized, the patient was discharged without any sequelae. Keywords: CVT, heparin, stroke
Effectiveness of Kenikir (Cosmos caudatus Kunth.) Leaf Extract on Duodenal Epithelial Damage of Aspirin Induced Male White Rats (Rattus norvegicus) Siti Alfina; Husnarika Febriani; Syukriah Syukriah
Journal of Agromedicine and Medical Sciences Vol 8 No 2 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i2.31304

Abstract

Aspirin or acetylsalicylic acid is one of the most common types of anti-inflammatory drugs used by people to relieve pain and inflammation. However, aspirin consumption can cause damage to the duodenal mucosal epithelium because it is acidic and inhibits the production of prostaglandins that are important in maintaining the mucosa. Duodenal damage due to aspirin consumption can be repaired using natural ingredients from plants with antioxidant and anti-ulcer effects, one of which is kenikir (Cosmos caudatus Kunth.) leaves. This study aims to determine the effectiveness of kenikir leaf extract against aspirin-induced histopathology and histomorphometry of the duodenum of male white rats. The research design used a completely randomized design (CRD) with 5 treatments and 5 replications. The treatments consisted of a normal group (feed and drink ad libitum), an aspirin group (induction of aspirin 200 mg/kgBW), and a treatment group with kenikir leaf extract at a dose of 700 mg/kgBW, 800 mg/kgBW, and 900 mg/kgBW. Preparation of histopathological preparations of the duodenum used the paraffin method with Hematoxylin-Eosin staining. Data were analyzed using one-way ANOVA and Duncan's follow-up test. The results of the histopathology study showed a significant difference (p<0.05) on the integrity score of duodenal mucosal epithelial cells. Histomorphometry had a significant effect on the height villi, basal width, apical width, and villous area (p<0.05). It can be concluded that administration of kenikir leaf extract at a dose of 900 mg/kgBW was most effective in improving the histopathology and duodenal histomorphometry of aspirin-induced male white rats. Keywords: aspirin, duodenum, kenikir (Cosmos caudatus Kunth.)
Cover AMS Vol. 8 No. 2 (2022)
Journal of Agromedicine and Medical Sciences Vol 8 No 2 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

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The Effect of Shallot Peel Ethanol Extract in Reducing Kidney MDA Levels in Diazinon-induced Wistar Rats Mukhammad Arif Hadi Khoiruddin; Dina Helianti; Muhammad Hasan; Rosita Dewi; Sheilla Rachmania
Journal of Agromedicine and Medical Sciences Vol 8 No 2 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i2.27424

Abstract

Diazinon is an organophosphate pesticide often used by farmer. The residue of diazinon may contaminate agricultural products and if accidentally consumed in a long term, may potentially led to health problems such as kidney disorders. Shallot (Allium cepa) peel was recently proposed to help recover the kidney damage due to its high flavonoid antioxidant content. This study aims to determine the antioxidant effect of shallot peel extract in reducing oxidative stress caused by diazinon with malondialdehyde (MDA) level indicator on the kidney of Wistar rats (Rattus norvegicus). This research was a true experimental with an in-vivo posttest-only control group design. The 28 rats were divided using a simple random sampling technique. The groups were the control group (K0), the diazinon group (K1), SPEE (Shallot Peel Ethanol Extract) groups which are P1 (300 mg/kg BW), P2 (600 mg/kg BW), P3 (900 mg/kg BW), P4 (1200 mg/kg BW) and P5 (2400 mg/kg BW). At the end of the study, the MDA kidney levels was analysed using the TBARS method. Effective doses were found in 600 mg/kg BW/day, 900 mg/kg BW/day, 1200 mg/kg BW/day, and 2400 mg/kg BW/day. The optimal dose of shallot peel extract in this study was 600 mg/kg BW/day. This study showed the effectiveness of shallot peel extract in reducing kidney MDA levels in diazinon-induced Wistar rats. Keywords: shallot peel, diazinon, kidney MDA level
Correlation between the Use of Shared Goods with Pediculosis Capitis among Students in Pondok Pesantren Subulussalam Palembang Rifka Purnama Sari; Dwi Handayani; Gita Dwi Prasasty; Chairil Anwar; Fatmawati Karim
Journal of Agromedicine and Medical Sciences Vol 8 No 2 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i2.29113

Abstract

Pediculosis capitis is a parasitic infection caused by the parasite Pediculus humanus var. capitis, which commonly found in densely crowded areas such as boarding schools. It is possible to contract pediculosis capitis by coming into direct or indirect contact with sufferers' hair. The goal of this study was to assess the prevalence of pediculosis capitis in students at Pondok Pesantren Subulussalam Palembang, as well as the association between the use of shared goods and the occurrence of pediculosis capitis. This study is a cross-sectional observational analytic study including 116 students who live permanently in Pondok Pesantren Subulussalam Palembang. A questionnaire was used to collect data, as well as direct observation of hair samples. The Chi-Square test, Fisher's exact test, and logistic regression were used to examine the results. The findings revealed that 35.3% of people had pediculosis capitis, and that there was a significant association between the use of mattresses (p=0.007), combs (p=0.024), and shared veils (p=0.006) and the occurrence of pediculosis capitis. The use of combs (p=0.018) and shared veils (p=0.001) were the most influential variables on the occurrence of pediculosis capitis, according to the results of the logistic regression test. The spread of pediculosis capitis disease is predicted to be reduced and prevented with improved personal hygiene, environment sanitation, and treatment. Keywords: Pediculosis capitis, boarding schools, Subulussalam, shared goods

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