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INDONESIA
ODONTO Dental Journal
Published by Universitas Islam Sultan Agung
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 387 Documents
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Median rhomboid glossitis as a sign of undiagnosed diabetes mellitus - a case report Sulistyani, Erna; Triwahyuni, Iin Eliana; Astuti, Pudji; Swandari, Rindang
Odonto : Dental Journal Vol 10, No 1 (2023): July 2023
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.10.1.7-13

Abstract

Background: Median Rhomboid Glossitis (MRG) is included in the group of nodular-plaque-like candidiasis, a subtype of chronic hyperplastic candidiasis. A lot of literature suggests that MRG is a manifestation of Diabetes Mellitus (DM), but the association between DM and MRG is unclear until now. This article reports an MRG found in an undiagnosed diabetes mellitus patient. Case: In October 2019, A 71-year-old man came to RSGM Universitas Jember to fix his loose denture. In the oral examination, we found a well-bordering, atrophic oval area surrounded by thick- soft white plaque. In his leg, we found itchy papule, ulcer, and crust multiple lesions. The microscopic examination of the white plaque swab showed that the spore and hyphae were found to fill all fields of view. The direct sugar blood level test showed that the sugar blood level was 390 mg/dL. We diagnosed the patient as having an MRG associated with suspected DM. Case Management: The patient was given miconazole oral gel and recommended to use it after cleaning the tongue three times a day. For diabetes management, the patient was referred to the Unit Medical Center University of Jember. The patient was diagnosed with diabetes mellitus and given oral-antidiabetics. After two weeks, the atrophic area had improved, and the white plaque had disappeared. Conclusion: General practitioners must be aware if they find the MRG in their patients caused a probability of underlying undiagnosed systemic disease, particularly diabetes mellitus on them.
The Potency of miRNA 221-3p as a Molecular Biomarker Of Temporomandibular Disoder: Narrative Review Rintoko, Bimo; Tanti, Ira; Bachtiar, Endang Winiati; Bachtiar, Boy Muchlis; Prihastari, Lisa
Odonto : Dental Journal Vol 12, No 3 (2025): December 2025
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.12.3.241-250

Abstract

United States. The trigeminal nerve might be the source of orof facial pain. Pain can be difficult to diagnose and treat due to the variability of pain complaints. miRNA 221-3p could be a potential biomarker for pain. Genetic polymorphisms and genetic mutations can lead to changes in the activity of inflammatory mediators, sex hormones, matrix-degrading enzymes, and the immune system, which affect bone remodeling homeostasis in the temporomandibular joint.Method: Scientific databases PubMed, Scopus, and Google Scholar were searched for articles published between 2013 and 2023 in order to conduct the study. 168 carefully selected publications providing information on possible biomarkers, particularly miRNA 221-3p, were included in the review of the literatureResult: Genetic polymorphisms and genetic mutations can lead to changes in the activity of inflammatory mediators, sex hormones, matrix-degrading enzymes, and the immune system, which affect bone remodeling homeostasis in the temporomandibular joint. In addition, activity changes were also observed in neurotransmitters and pain receptors, which resulted in relatively high pain sensitivity. Thus, this condition also increases susceptibility to TMD. Genetic analysis and biomarkers of temporomandibular disorders may improve sensitivity and specificity measures in diagnosing and treating patients with TMDConclusion: As a multifactorial disease, genetic factors are risk factors for TMD. Genetic polymorphisms and genetic mutations can lead to changes in the activity of inflammatory mediators, sex hormones, matrix-degrading enzymes, and the immune system, which affect bone remodeling homeostasis in the TMD
The Effect Of Bisphosphonate Risedronate Emulgel On The Inhibition Of Relaps Tooth Movement Utari, Tita Ratya; Mirnacantika, Bellinda Aprillia; Zulfikar, Trinadya Muhammad; Syadzanisa, Farah Fauzia; Wulandari, Ika Sukma
Odonto : Dental Journal Vol 10, No 1 (2023): July 2023
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.10.1.90-99

Abstract

Background: Orthodontic treatment is performed to correct the malocclusion, and after treatment is complete. The position of the teeth must be maintained because the teeth can move back to their original position, commonly known as relapse. Various attempts have been made, such as using retainers, and various studies have used pharmacological agents such as bisphosphonate risedronate to inhibit relapse, but these studies still used the injection method, which is inconvenient to apply and has a systemic effect. For this reason, changing the bisphosphonate preparation to an emulgel will facilitate its application and have a local effect, but it is necessary to test and determine its effectiveness in inhibiting the relapse. Method: An experimental laboratory study was conducted on 18 guinea pigs, which were divided into three groups: I (control), II (emulgel without risedronate), and III (emulgel with risedronate). The teeth were moved with open coil springs on both lower incisors for seven days, stabilized for seven days, and emulgel applied in groups II and III. The coil spring was removed, and the distance between the two incisors was measured on the third and seventh days. Result: Using One-Way ANOVA and Post Hoc LSD, the data analysis results showed significant differences between the control and the risedronate emulgel groups on the third and seventh days. The largest relapse occurred in the control group, while the smallest was in the emulgel group with risedronate. Conclusion: These results indicate that risedronate bisphosphonate in the form of emulgel influences inhibiting the movement of tooth relapse
Datura metel SEED NANO CHITOSAN EXTRACT GEL’S EFFECT ON ANGIOGENESIS WOUND HEALING OF WISTAR RAT Asriningrum, Vika; Bramanti, Indra; Ardhani, Retno
Odonto : Dental Journal Vol 12, No 3 (2025): December 2025
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.12.3.269-279

Abstract

Background: Datura metel possesses anti-inflammatory properties useful for treating oral mucosal injuries common in children, where healing relies on angiogenesis. Nano chitosan technology addresses herbal bioavailability issues. This study investigated the effect of 1% Datura metel seed nano chitosan extract gel on angiogenesis in Wistar rats. Methods: Eighteen Wistar rats were divided into three groups: 1% Datura metel seed chitosan extract, 1% nano chitosan extract, and a control group. Gels were applied to mandibular gingival wounds with assessments on days 3 and 5. Histological angiogenesis counts were analyzed using two-way ANOVA (p<0.05). Results: Significant differences in angiogenesis counts were found among the chitosan extract, nano chitosan extract, and positive control groups. Furthermore, variations in angiogenesis counts were observed between day 3 and day 5 across all groups. Conclusion: The 1% Datura metel seed chitosan extract gel demonstrated a greater effect in triggering angiogenesis compared to the 1% nano chitosan extract and the positive control.
Effectiveness of Licorice Extract (Glycyrrhiza glabra L.) on Traumatic Ulcer with Parameter Study: Macrophage, Neutrophil, and Lymphocyte Syifa, Liftia Layyinatus; Sari, Rina Kartika; Ismail, Dea Maynur Shalima; Pradisha, Rizqila Diva
Odonto : Dental Journal Vol 13, No 1 (2026): April 2026
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.13.1.%p

Abstract

Background: Traumatic oral ulcers are common lesions characterized by epithelial loss, pain, and erythematous halos. Healing occurs through four stages: haemostasis, inflammation, proliferation, and remodelling. Licorice root (Glycyrrhiza glabra L.) is known for its anti-inflammatory and immunomodulatory properties. This study aimed to evaluate the effectiveness of licorice extract at various concentrations on macrophage, neutrophil, and lymphocyte cell counts during traumatic ulcer healing.Methods: A post-test only group design was used with five groups: three treatment groups receiving 5%, 10%, and 15% licorice extract, and two control groups (positive: Aloclair; negative: aquadest), each with six mice. Ulcers were induced using a heated burnisher on the labial mucosa. Treatments were applied twice daily using a nano mouth spray. After euthanasia, labial tissues were fixed, processed, and stained with Hematoxylin-Eosin for histological examination under 400× magnification.Result: Phytochemical analysis revealed high flavonoid (44.669) and saponin (38.802) contents in licorice extract. Statistical tests showed significant differences (p < 0.05) in macrophage, neutrophil, and lymphocyte counts among groups. The 10% extract group showed the highest immune cell response, suggesting optimal anti-inflammatory and immunomodulatory effects at this concentration.Conclusion: Licorice extract effectively promotes the healing of traumatic oral ulcers. Among tested concentrations, the 10% extract provided the best therapeutic effect, accelerating healing and regulating inflammatory cell activity more effectively than other doses or controls.
Definitive Endocrown Restoration in First Molar Right Mandibular After Multiple-Visit Endodontic Treatment: A Case Report Mahardika, Christina; Aini, Rizqika Sufi; Asyafiq, Luthfan; Abdurrohman, Muhamat Muhtar S
Odonto : Dental Journal Vol 13, No 1 (2026): April 2026
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.13.1.%p

Abstract

Background: Root canal treatment is a dental procedure aimed at preserving teeth and roots that have been infected by bacteria, with the expectation of restoring the tooth’s normal function and aesthetics. The selection of an appropriate final restoration plays a significant role in supporting the success of root canal therapy.Method: A 22-year-old male patient presented to the conservative dentistry clinic with a chief complaint of a cavity in the lower right molar that had been present for the past two years. The patient reported experiencing pain one year ago when the tooth was used for chewing or exposed to sweet and cold stimuli, accompanied by swelling, but no treatment was sought at that time. Currently, the patient no longer experiences pain but feels discomfort due to food impaction in the cavity. The ICD-10 diagnosis for tooth 46 was necrosis of the pulp.Result: The patient reported comfort during mastication and expressed satisfaction with the final restoration. These findings indicate the clinical success of the endocrown restoration, achieving optimal retention, occlusal function, and esthetic outcome.Conclusion: Endocrowns preserve more remaining tooth structure and provide good marginal adaptation. One week after placement, the evaluation showed satisfactory marginal adaptation with no post-treatment complaints. Therefore, endocrowns can be considered a conservative, functional, and esthetic restorative option for endodontically treated posterior teeth.     
Pharmacotherapy And Behavioural-Modifying-Lifestyle For Oral Lesions Management In Multimorbid Patient Post-Pyelolithotomy: A Case Report Pramitha, Selviana Rizky; Izzati, Arissa; Apriasari, Maharani Laillyza; Carabelly, Amy Nindia; Puspitasari, Dewi
Odonto : Dental Journal Vol 13, No 1 (2026): April 2026
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.13.1.%p

Abstract

Background: Chronic kidney disease (CKD), a recognized complication of pyelolithotomy along with multimorbidity in the elderly population, presents a higher incidence of oral lesions. Further damage to the renal vasculature interchangeably affects oral-systemic conditions. We report oral lesions management in MCC patient post-pyelolithotomy for better outcomes.  Case: A 65-year-old male patient complained of painful ulceration on the atrophic tongue for two weeks with a fair oral hygiene score. The condition had been managed with various topical agents alternately with no improvement. There was a history of pyelolithotomy and emergency room admission. Laboratory examination presented diabetes mellitus, stage 3B kidney disease and anemia of chronic disease. A diagnosis of ulcerative-type uremic stomatitis with atrophic glossitis in multimorbid patient was obtained. Pharmacotherapy of oral lesion including aloe vera extract mouthwash and povidone-iodine mouthwash showed improvement on the following day. Behavioural-modifying lifestyle involved physical activity, healthy eating, and adherence to treatment (oral hygiene maintenance and regular dental appointment). Systemic conditions were managed by multidiscipline treatment with Internal Medicine. Conclusion: Pharmacotherapy and behavioral modifying lifestyle may support a better prognosis for oral manifestation in multimorbid patient post pyelolithotomy

Page 39 of 39 | Total Record : 387

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