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INDONESIA
Biomedical Journal of Indonesia
Published by Universitas Sriwijaya
ISSN : 24077097     EISSN : -     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Biomedical Journal of Indonesia is an open access, peer-reviewed journal that focus on basic medical sciences, emphasizing on providing the molecular studies of biomedical problems and molecular mechanisms to integrate researches in all aspects of human health. BJI is dedicated to publishing original research and review articles covering all aspects of biomedical sciences.
Arjuna Subject : Kedokteran - Anatomi
Articles 392 Documents
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The Relationship of Obesity with Range Of Motion (ROM) On The Ankle Indriyani Indriyani; Mellyana Cahyadi
Biomedical Journal of Indonesia Vol. 9 No. 3 (2023): Vol 9, No 3, 2023
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v9i3.171

Abstract

Introduction. Obesity is weight gain beyond the limits of physical and skeletal needs due to excessive accumulation of body fat that may increase risk factors for musculoskeletal disorders. A musculoskeletal disorder that can occur is a limited range of motion of a joint. This study aimed to identify the relationship between obesity and ankle range of motion (ROM). Methods. This study was conducted using an analytical observational study with an overall sample of 311 students who met the inclusion criteria. The sample for this study was students’ class of the Muhammadiyah Palembang's School of Medicine from 2018 to 2020 and was extracted using the total extraction method. The population of this study is Palembang students. Results. The study found that 238 students (76.5%) were not obese and 65 students (20.9%) were obese. Among obese college students, 51 college students (69.9%) had normal dorsiflexion ROM and 22 college students (30.1%) had abnormal dorsiflexion ROM. Obese students had normal plantarflexion ROM in her 20 students (27.4%) and students with abnormal plantarflexion ROM in her 53 students (72.6%). 195 students (81.9%) had normal dorsiflexion ROM and 43 students (49.7%) had abnormal dorsiflexion ROM. 185 students (77.7%) had normal plantarflexion ROM and 53 students (22.3%) had abnormal plantarflexion ROM. Conclusion. Suggesting an association between obesity and the Range of Motion (ROM) in the ankle joint.
Excessive Sodium and Insufficient Potassium Consumption Can Elevate the Risk of Developing Hypertension Nanda Maharani Saqadifa; Ardesy Melizah Kurniati; Sadakata Sinulingga; Syarif Husin; Rizma Adlia Syakurah; Syarinta Adenina
Biomedical Journal of Indonesia Vol. 9 No. 3 (2023): Vol 9, No 3, 2023
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v9i3.172

Abstract

Introduction. Physiologically, there are setbacks and weaknesses in body functions in the elderly. This can cause inadequate food intake or eating imbalances in the elderly. Increased blood pressure is influenced by many factors such as sodium and potassium intake and less potassium intake can increase blood pressure. The purpose of this study was to determine the relationship of sodium and potassium intake from food with blood pressure in the elderly in the community dr. Mohammad Hoesin Hospital. Methods. An observational-analytic study was conducted on 120 elderly people using a cross-sectional research design conducted in the elderly community of dr. Mohammad Hoesin Hospital in October-November 2019. The sample of this study were members of the elderly community aged over 60 years, present when the study was conducted, willing to become a respondent and signed an informed consent. Data was obtained through filling out food record questionnaires, food recall interviews, personal data interviews, and direct measurement of blood pressure and nutritional status. To meet the research objectives, data were analyzed by Chi-square test. Results. In this study, there were 120 elderly people consisting of 3 men and 117 women. There was a significant relationship between sodium and potassium intake and blood pressure (p=0,003 and p=0,0001). Conclusion. There is a significant relationship between sodium and potassium intake with blood pressure in the elderly.
Knowledge Level of Dry Skin Care in The Elderly at The Koto Tangah Regional Health Center Fuji Lestari Kursiussamawati; Irma Primawati; Sriwahyuni Sriwahyuni
Biomedical Journal of Indonesia Vol. 10 No. 1 (2024): Vol 10, No 1, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v10i1.169

Abstract

Introduction. The occurrence of dry skin in the elderly requires good and extra skin care. The incidence and severity of dry skin increases with age. Dry skin conditions in the elderly can cause discomfort and can even cause disease, such as atopic dermatitis which is a disease caused by inflammation of the skin. This research aims to determine the level of knowledge of dry skin care in the elderly at the Koto Tangah Health Center in the city of Padang. Methods. This research was a descriptive observational study with a cross-sectional design. The sample in this study was selected by technique consecutive sampling and this research requires a minimum of 100 samples. Results. The knowledge level of dry skin care of the respondents is mostly in the medium category  (62%), the age of the majority of respondents was in the age category of 60-70 years (65%), the sex of the majority of respondents was male (53%), most respondents had primary school education (56%), worked as laborer (26%), and live with their families (83%). Conclusion. The level of knowledge of nursing for most of the elderly dry skin is in the medium category.
Risk of Vitamin D Deficiency in Medical Students Based on The Characteristics of Food Intake and Sun Exposure Vienna Dwinda Putri; Syarif Husin; Ardesy Melizah Kurniati; Julius Anzar; Ziske Maritska; Syarinta Adenina
Biomedical Journal of Indonesia Vol. 10 No. 1 (2024): Vol 10, No 1, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v10i1.173

Abstract

Introduction. The need for Vitamin D can be fulfilled through direct synthesis from Vitamin D stores in the skin with the help of ultraviolet B rays. Therefore, sufficient Vitamin D intake and sun exposure are needed. Most of the activities of medical students on campus are indoors from morning to evening, so it is suspected that there is a risk of Vitamin D deficiency. The purpose of this study was to identify the risk of Vitamin D deficiency based on the characteristics of Vitamin D from food intake and sun exposure in Faculty of Medicine students, Universitas Sriwijaya. Methods. This research was a descriptive study using a questionnaire and observation. Age, sex, BMI and use of related drugs were recorded. The food survey method used was the repeated food recall which was then analyzed using Nutrisurvey 2007. Subjects filled out a questionnaire to obtain data on exposure scores and sun protection scores. The research subjects were students of the Faculty of Medicine, Universitas Sriwijaya who were willing to sign informed consent and were present at the time of sampling. Results. The results from the data of 259 subjects showed that 98.8% of the subjects did not meet their vitamin D intake needs, with an average consumption of 123 ± 142 IU. Types of food that contribute the most Vitamin D are catfish (40%) and eggs (20%). None of the subjects took supplements containing Vitamin D. Sun exposure was sufficient for most subjects (62.9%), but most subjects were at risk of deficiency due to the use of sun protection (62.2%) Conclusion. There is a risk of deficiency in most medical students due to a lack of Vitamin D intake and the use of sun protection.
Inhibition Effect of N-Hexane Extract of Cherry Mistletoe Leaves (Dendropthtoe pentandra (L) Miq.) on Xanthine Oxidase Mario Saputra; Sadakata Sinulingga; Subandrate Subandrate
Biomedical Journal of Indonesia Vol. 10 No. 1 (2024): Vol 10, No 1, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v10i1.175

Abstract

Introduction. Cherry leaf extract has been found to have the potentiality to impede the xanthine oxidase enzyme. It is believed that cherry mistletoe leaves also possess similar properties as they are hemiparasites of their host. This study aims to determine the inhibition effect of N-Hexane extract of mistletoe cherry leaves on the xanthine oxidase. Methods. This research was conducted as an experimental in-vitro study. Cherry mistletoe leaves were extracted by N-Hexane solvent. The extract was divided into five doses, i.e. 40 mg/L, 20 mg/L, 10 mg/L, 5 mg/L, and 2.5 mg/L. Phytochemical screening was conducted to identify secondary metabolites. The impact of xanthine oxidase inhibition was quantified using a UV-vis spectrophotometer at wavelength of 400 nm. Results. N-Hexane extract of cherry mistletoe leaves contains alkaloids and triterpenoids. N-Hexane extract of mistletoe cherry leaves at a dose of 40 mg/L, 20 mg/L, 10 mg/L, 5 mg/L, and 2.5 mg/L was able to inhibit the xanthine oxidase enzyme with the line equation y = -0.2543x+ 91.305. The IC50 value for the N-Hexane extract of cherry mistletoe leaves is 162 mg/L Conclusion. N-Hexane extract of cherry mistletoe leaves has the potency to inhibit the xanthine oxidase enzyme in the medium category.
Blood Transfusion Incidence and Sociodemographics Relationship with Anxiety Levels of Thalassemia Major Parents Safyudin; Dita Tri Ramadianti; Subandrate; Liniyanti D. Oswari; Eka Handayani Oktharina
Biomedical Journal of Indonesia Vol. 10 No. 1 (2024): Vol 10, No 1, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v10i1.177

Abstract

Introduction. Thalassemia is inherited anemia in an autosomal recessive manner with a disruption in hemoglobin synthesis that causes a decreased amount of hemoglobin and anemia. Routine blood transfusions carried out by sufferers and parents' sociodemographic factors can cause an increased psychological burden on the patient's parents. This study investigated the relationship between the incidence of blood transfusions in pediatric patients and parents' sociodemographics with the anxiety level of parents in pediatric thalassemia major patients at RSMH Palembang. This study used an observational analytical method with a cross-sectional study design. Methods. This study used an observational analytical method with a cross-sectional study design. This study consisted of 42 respondents. This study used primary data from interviews and filling out the Z-SAS questionnaire and secondary data from medical records. Results. The distribution of blood transfusion found in thalassemia major children who had transfusions £1 time/month was 40.5%. Based on sociodemographics, 81% of respondents were women, 26.2% had a low level of education, 28.6% were in early adulthood, 61.9% had less income, 81% had 1 child, and 14.3% had thalassemia Major children diagnosed £1 year. The level of anxiety that dominated the results was normal/not anxious (72.8%) and mild anxiety (26.2%). (P Value= 0.305; 0.174; 1.00; 0.095; 0.158; 0.657; 0.644). Conclusion. There was no relation between blood transfusion incidence in children with thalassemia major and sociodemographic of parents with anxiety levels of children with thalassemia major parents in RSMH Palembang.
Comparison of Oxygen Saturation Dynamics Between Types of Acute Stroke in Early Hospitalization Period Naura Waliya Maharani; Ita Muharram Sari; Patwa Amani
Biomedical Journal of Indonesia Vol. 10 No. 1 (2024): Vol 10, No 1, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v10i1.181

Abstract

Introduction. Stroke is the number one cause of death and disability in Indonesia. It was found that the incidents of stroke were higher at ages over 45 years. The use of pulse oximeter is an efficient step in monitoring oxygenation in stroke patients. Decreased oxygen levels can cause neurological deficits such as cognitive impairment, causing patients to have problems in attention and executive functions. This study aims to determine the relationship between the type of acute stroke and oxygen saturation in early hospitalization period. Methods. This research was carried out from November to December 2023 at the National Brain Center Hospital, Jakarta, using a cross sectional approach. Information on diagnosis and oxygen saturation values were obtained through medical records, with a total of 70 patients as subjects. Subjects selected through simple random sampling with patients age over 45 years. Statistical analysis used the Mann Whitney test with a significantly different p value <0.05. Results. A total of 68.6% of the subjects were male with ages of 45-59 dominated the subjects at 51.4%. Statistical tests on the type of acute stroke with oxygen saturation values produced a value of p = 0.044 (p < 0.05) on the 3rd day of hospitalization. These results indicate a significant relationship between the type of acute stroke and the oxygen saturation value on the 3rd day of hospitalization. Conclusion. There is a significant correlation between the type of acute stroke and oxygen saturation in the 3rd day of hospitalization.
Quality of Life in Pelvic Organ Prolapse Patients with Operative Therapy at RSUP Dr. Mohammad Hoesin Mutia Adilah Almenata; Hadrians Kesuma Putra; Septi Purnamasari; Ratih Krisna; Abarham Martadiansyah
Biomedical Journal of Indonesia Vol. 10 No. 1 (2024): Vol 10, No 1, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v10i1.183

Abstract

Introduction. Pelvic organ prolapse is a condition where the pelvic organs descend from their original position and protrude into the vagina. This condition causes several complaints in the patients that can interfere with their daily activities and have an impact on their quality of life. One of the treatments that can be given to patients with POP is operative therapy, which one of the goals is to improve patient's quality of life. This study aims to determine the quality of life of pelvic organ prolapse patients with operative therapy at Dr. Mohammad Hoesin Hospital Palembang. Methods. This study used an observational analytical method with a cross-sectional study design. This study consisted of 17 respondents. This study used primary data from interviews using the P-QOL questionnaire guidelines and secondary data from medical records. Results. This study showed an improvement in the quality of life of pelvic organ prolapse patients in all P-QOL quality of life domains (p<0.05) after receiving operative therapy compared to before receiving operative therapy. Analysis of the effect of confounding factors on the total quality of life score showed that age (p=0.138), BMI (p=0.999), parity (p=0.468), degree of POP (p=0.439), and type of surgery (p=0.814) did not have a significant influence on the quality of life of postoperative POP patients. Conclusion. There was a significant improvement in the quality of life in pelvic organ prolapse patients after receiving operative therapy, and there is no significant relationship between age, BMI, parity, degree of POP, also type of surgery on the quality of life in postoperative POP patients.
General Knowledge or The Use of Menstrual Cycle Tracking App among Medical Students at Sriwijaya University Zafira Alysha; Eka Handayani Oktharina; Liniyanti D. Oswari; Hadrians Kesuma Putra; Rara Inggarsih
Biomedical Journal of Indonesia Vol. 10 No. 2 (2024): Vol 10, No 2, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v10i2.186

Abstract

Introduction. As technology and science develop, the menstrual cycle can be known practically by using menstrual cycle tracking applications on gadgets. The many features in the application are an added value, so many women choose to use menstrual cycle tracking applications compared to other platforms. This research aims to identify the general level of knowledge or use of the menstrual cycle tracking app among medical students at the Faculty of Medicine Sriwijaya University. Methods. This type of research is descriptive using a survey. The sample in this study was female medical students at the Faculty of Medicine Sriwijaya University class 2018—2023 who fulfilled the inclusion and exclusion criteria. Sampling was collected by total sampling. Results.  In this study, 868 respondents participated, it was found that 467 (53.8%) had the highest level of knowledge, namely with “good” category. 685 (78.9%) controlled their menstrual cycles. 450 (65%) used a menstrual cycle tracking application with the most duration of use being ≥ 1 year 311 (49.8%). The most widely used application name is Flo My Health & Period Tracker 308 (66.5%). 294 (63.9%) chose the quite satisfied category for the level of satisfaction with using the application. In addition, 396 (86.1%) chose the sufficient category for the level of accuracy in using the application. Conclusion. Female medical education students at the Faculty of Medicine, Sriwijaya University have a general level of knowledge with the dominance of the category “good” and a usage rate of 467 (53.8%) in the menstrual cycle monitoring application.
Flavonoids and Their Role As Anti-Inflammatory Agents Fatmawati; Aliah Ramadhani Puteri; Humairah Binti Huda
Biomedical Journal of Indonesia Vol. 10 No. 2 (2024): Vol 10, No 2, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v10i2.187

Abstract

The human civilizations have been using plants and herbs for their rich sources of phytonutrients and bioactive compounds. Polyphenols are one of the groups of beneficial compounds found naturally, they include a wide variety of molecules and are divided into 4 main categories, which are flavonoids, phenolic acids, lignans, and stilbenes. It is estimated that more than 10,000 flavonoid compounds have been isolated and then identified, with the results finding that the majority of flavonoids are widely accepted as therapeutic agents. It is found in various flowers, fruits, and leaves such as red peppers, celery, parsley, chamomile, mint, and ginkgo biloba. Flavonoids are known for their anti-inflammatory properties using a mechanism that is thought to be different. The mechanism used may include an enzyme inhibition mechanism for enzymes that regulate transcription factors. This has a very important role, one of the roles being the control of mediators involved in an inflammatory process. The study for this systematic review was conducted without a time constraint using scientific databases such as Google Scholar and ScienceDirect, with 5 years’ time limitation. Previous research has validated the pharmacological characteristics of some flavonoids and their potential health advantages.

Page 35 of 40 | Total Record : 392

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